Dataset | Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos |
Phenotype | phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos |
Upregulated in class | DMpreB |
GeneSet | REACTOME_DIABETES_PATHWAYS |
Enrichment Score (ES) | -0.6235587 |
Normalized Enrichment Score (NES) | -1.6390623 |
Nominal p-value | 0.0 |
FDR q-value | 0.023496006 |
FWER p-Value | 0.378 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | IGFBP4 | 20670 9160 | 674 | 3.787 | -0.0184 | No | ||
2 | ETFB | 18279 | 960 | 3.019 | -0.0194 | No | ||
3 | VAMP2 | 20826 | 1457 | 2.052 | -0.0364 | No | ||
4 | RPS25 | 13270 | 1473 | 2.031 | -0.0275 | No | ||
5 | PKM2 | 3642 9573 | 1619 | 1.831 | -0.0266 | No | ||
6 | NDUFS5 | 9296 | 1631 | 1.814 | -0.0185 | No | ||
7 | RPL28 | 5392 | 1691 | 1.736 | -0.0134 | No | ||
8 | SRP14 | 9894 | 1901 | 1.516 | -0.0174 | No | ||
9 | DLD | 2097 21090 | 2040 | 1.364 | -0.0184 | No | ||
10 | RPL11 | 12450 | 2068 | 1.339 | -0.0134 | No | ||
11 | RPL39 | 12496 | 2099 | 1.311 | -0.0088 | No | ||
12 | ETFDH | 15313 | 2104 | 1.305 | -0.0027 | No | ||
13 | IQGAP1 | 6619 | 2207 | 1.211 | -0.0025 | No | ||
14 | EXOC8 | 4161 | 2351 | 1.079 | -0.0050 | No | ||
15 | RPS28 | 12009 | 2402 | 1.027 | -0.0028 | No | ||
16 | HSPA5 | 9045 | 2491 | 0.981 | -0.0029 | No | ||
17 | UQCRB | 12545 | 2534 | 0.936 | -0.0007 | No | ||
18 | RPS4X | 9756 | 2598 | 0.876 | 0.0001 | No | ||
19 | RPL5 | 9746 | 2754 | 0.736 | -0.0048 | No | ||
20 | RPS15A | 6476 | 2781 | 0.711 | -0.0028 | No | ||
21 | RPLP1 | 3010 | 2898 | 0.616 | -0.0061 | No | ||
22 | NFYA | 5172 | 2902 | 0.613 | -0.0033 | No | ||
23 | COX8A | 8777 | 2967 | 0.573 | -0.0041 | No | ||
24 | NDUFA6 | 12473 | 3007 | 0.551 | -0.0035 | No | ||
25 | RPS20 | 7438 | 3032 | 0.538 | -0.0023 | No | ||
26 | RPL37A | 9744 | 3195 | 0.452 | -0.0089 | No | ||
27 | NDUFS4 | 9452 5157 3173 | 3225 | 0.439 | -0.0083 | No | ||
28 | RPS21 | 12356 | 3474 | 0.332 | -0.0202 | No | ||
29 | SSR4 | 24303 5519 | 3589 | 0.287 | -0.0250 | No | ||
30 | F2 | 14524 | 3610 | 0.281 | -0.0247 | No | ||
31 | IGFBP5 | 4899 | 3684 | 0.260 | -0.0274 | No | ||
32 | RPS5 | 18391 | 3988 | 0.184 | -0.0430 | No | ||
33 | RPL18A | 13358 | 4002 | 0.181 | -0.0428 | No | ||
34 | OGDH | 9502 1412 | 4152 | 0.154 | -0.0501 | No | ||
35 | KLF4 | 9230 4962 4963 | 4236 | 0.143 | -0.0540 | No | ||
36 | RPL27 | 9740 | 4270 | 0.139 | -0.0551 | No | ||
37 | UQCRFS1 | 21499 | 4321 | 0.132 | -0.0572 | No | ||
38 | PLA2G7 | 23233 | 4367 | 0.123 | -0.0590 | No | ||
39 | RPS13 | 12633 | 4549 | 0.101 | -0.0683 | No | ||
40 | CHRM3 | 21547 | 4608 | 0.095 | -0.0710 | No | ||
41 | PGK1 | 9557 5244 | 4661 | 0.090 | -0.0734 | No | ||
42 | RPS29 | 9754 | 4867 | 0.075 | -0.0841 | No | ||
43 | SDHA | 12436 | 5741 | 0.039 | -0.1313 | No | ||
44 | LEP | 17505 | 7223 | 0.011 | -0.2114 | No | ||
45 | NKX2-2 | 5176 | 7599 | 0.005 | -0.2317 | No | ||
46 | PRKAR2B | 5288 2107 | 7813 | 0.002 | -0.2433 | No | ||
47 | KIF5B | 4955 2031 | 8124 | -0.002 | -0.2600 | No | ||
48 | SYT5 | 17986 | 8182 | -0.003 | -0.2631 | No | ||
49 | MMP2 | 18525 | 8553 | -0.007 | -0.2831 | No | ||
50 | IGFBP1 | 20948 | 8685 | -0.009 | -0.2902 | No | ||
51 | SRP19 | 2004 12341 | 8903 | -0.012 | -0.3019 | No | ||
52 | IGFALS | 9158 | 9094 | -0.015 | -0.3121 | No | ||
53 | PFKFB1 | 9552 | 9249 | -0.017 | -0.3204 | No | ||
54 | NDUFB4 | 22596 7541 | 9397 | -0.019 | -0.3282 | No | ||
55 | PDX1 | 16621 | 9558 | -0.022 | -0.3368 | No | ||
56 | GCG | 14578 | 9571 | -0.022 | -0.3373 | No | ||
57 | EXOC5 | 8370 | 9857 | -0.026 | -0.3527 | No | ||
58 | NDUFA4 | 9451 | 9985 | -0.028 | -0.3594 | No | ||
59 | SRP54 | 6282 | 10085 | -0.030 | -0.3646 | No | ||
60 | RPL17 | 11429 6653 | 10174 | -0.031 | -0.3692 | No | ||
61 | RAP1A | 8467 | 10262 | -0.033 | -0.3738 | No | ||
62 | RPS3 | 6549 11295 | 10826 | -0.043 | -0.4041 | No | ||
63 | FFAR1 | 10583 | 11487 | -0.057 | -0.4396 | No | ||
64 | CTSL1 | 4574 | 11624 | -0.061 | -0.4467 | No | ||
65 | PRKCA | 20174 | 11681 | -0.062 | -0.4494 | No | ||
66 | RPL18 | 450 5390 | 11693 | -0.062 | -0.4497 | No | ||
67 | ADRA2A | 4355 | 11707 | -0.063 | -0.4501 | No | ||
68 | RPSA | 19270 4984 | 12235 | -0.081 | -0.4783 | No | ||
69 | MBTPS1 | 18730 3809 3770 | 12260 | -0.082 | -0.4792 | No | ||
70 | RPS16 | 9752 | 12347 | -0.086 | -0.4834 | No | ||
71 | ERN1 | 8137 | 12954 | -0.116 | -0.5157 | No | ||
72 | SDHB | 2348 12566 14880 | 13036 | -0.121 | -0.5195 | No | ||
73 | RPL19 | 9736 | 13396 | -0.146 | -0.5382 | No | ||
74 | EIF2S1 | 4658 | 13442 | -0.150 | -0.5400 | No | ||
75 | GLP1R | 23304 | 13452 | -0.151 | -0.5397 | No | ||
76 | SLC2A2 | 15623 1880 1855 | 13596 | -0.165 | -0.5467 | No | ||
77 | PCSK2 | 9537 5231 14824 | 13823 | -0.187 | -0.5580 | No | ||
78 | RPL41 | 12611 | 13947 | -0.199 | -0.5637 | No | ||
79 | KCNJ11 | 17822 | 14161 | -0.227 | -0.5742 | No | ||
80 | KLK3 | 16337 | 14579 | -0.302 | -0.5953 | No | ||
81 | IGFBP6 | 9161 | 14613 | -0.310 | -0.5956 | No | ||
82 | RPL37 | 12502 7421 22521 | 14614 | -0.310 | -0.5942 | No | ||
83 | ABCC8 | 9941 11649 | 14670 | -0.324 | -0.5956 | No | ||
84 | IGF1 | 3352 9156 3409 | 14678 | -0.326 | -0.5944 | No | ||
85 | PFKFB2 | 4116 5242 | 14687 | -0.329 | -0.5933 | No | ||
86 | ATP5B | 19846 | 14751 | -0.346 | -0.5950 | No | ||
87 | NDUFC1 | 7287 12339 | 14799 | -0.355 | -0.5959 | No | ||
88 | RPS14 | 9751 | 14830 | -0.364 | -0.5957 | No | ||
89 | RPS17 | 9753 | 14924 | -0.392 | -0.5989 | No | ||
90 | RPL8 | 22437 | 15022 | -0.422 | -0.6021 | No | ||
91 | COX4I1 | 18444 | 15393 | -0.584 | -0.6194 | No | ||
92 | NDUFS3 | 7553 12683 | 15411 | -0.600 | -0.6174 | No | ||
93 | CPE | 18868 | 15525 | -0.666 | -0.6204 | Yes | ||
94 | RPS23 | 12352 | 15582 | -0.699 | -0.6201 | Yes | ||
95 | NDUFS8 | 23950 | 15598 | -0.708 | -0.6175 | Yes | ||
96 | TPI1 | 5795 10212 | 15661 | -0.753 | -0.6172 | Yes | ||
97 | NDUFB10 | 23084 | 15680 | -0.766 | -0.6145 | Yes | ||
98 | SRP72 | 16819 | 15705 | -0.787 | -0.6121 | Yes | ||
99 | ATP5C1 | 8635 | 15756 | -0.827 | -0.6108 | Yes | ||
100 | NDUFA2 | 9450 | 15760 | -0.829 | -0.6070 | Yes | ||
101 | SEC11A | 12144 | 15773 | -0.840 | -0.6036 | Yes | ||
102 | FAU | 8954 | 15902 | -0.940 | -0.6061 | Yes | ||
103 | NDUFB7 | 12429 | 15927 | -0.961 | -0.6028 | Yes | ||
104 | SUCLG1 | 17409 1059 | 16010 | -1.003 | -0.6024 | Yes | ||
105 | ATP5J | 880 22555 | 16024 | -1.008 | -0.5983 | Yes | ||
106 | UQCRC1 | 10259 | 16148 | -1.088 | -0.5997 | Yes | ||
107 | RPS3A | 9755 | 16189 | -1.130 | -0.5965 | Yes | ||
108 | DDOST | 16021 | 16255 | -1.186 | -0.5943 | Yes | ||
109 | COX5B | 4552 | 16259 | -1.193 | -0.5888 | Yes | ||
110 | CS | 19839 | 16370 | -1.292 | -0.5885 | Yes | ||
111 | NDUFA11 | 12832 | 16407 | -1.341 | -0.5841 | Yes | ||
112 | NDUFB5 | 12277 | 16443 | -1.381 | -0.5794 | Yes | ||
113 | NDUFC2 | 18183 | 16451 | -1.403 | -0.5730 | Yes | ||
114 | ATF4 | 22417 2239 | 16551 | -1.513 | -0.5711 | Yes | ||
115 | NDUFB8 | 7418 | 16575 | -1.535 | -0.5650 | Yes | ||
116 | ATP5D | 19949 | 16608 | -1.558 | -0.5593 | Yes | ||
117 | COX7C | 8776 | 16715 | -1.648 | -0.5571 | Yes | ||
118 | NDUFAB1 | 7667 | 16758 | -1.695 | -0.5513 | Yes | ||
119 | COX6A1 | 8774 4553 | 16863 | -1.830 | -0.5482 | Yes | ||
120 | ATP5J2 | 12186 | 16915 | -1.907 | -0.5418 | Yes | ||
121 | SEC61G | 9795 | 17000 | -2.030 | -0.5366 | Yes | ||
122 | ATP5O | 22539 | 17106 | -2.180 | -0.5319 | Yes | ||
123 | COX6B1 | 4283 8479 | 17117 | -2.194 | -0.5219 | Yes | ||
124 | GNAS | 9025 2963 2752 | 17156 | -2.230 | -0.5133 | Yes | ||
125 | ATP5E | 14321 | 17201 | -2.299 | -0.5046 | Yes | ||
126 | UQCRC2 | 18102 | 17206 | -2.306 | -0.4938 | Yes | ||
127 | RPL6 | 9747 | 17219 | -2.333 | -0.4833 | Yes | ||
128 | PDHA1 | 24020 | 17250 | -2.401 | -0.4734 | Yes | ||
129 | ATP5A1 | 23505 | 17266 | -2.447 | -0.4625 | Yes | ||
130 | ATP5F1 | 15212 | 17289 | -2.498 | -0.4517 | Yes | ||
131 | RPS2 | 9279 | 17318 | -2.573 | -0.4409 | Yes | ||
132 | ATP5I | 8637 | 17360 | -2.639 | -0.4305 | Yes | ||
133 | IDH3G | 24132 | 17368 | -2.647 | -0.4182 | Yes | ||
134 | RPLP2 | 7401 | 17406 | -2.715 | -0.4072 | Yes | ||
135 | COX6C | 8775 | 17413 | -2.723 | -0.3945 | Yes | ||
136 | RPL4 | 7499 19411 | 17456 | -2.820 | -0.3833 | Yes | ||
137 | NDUFS7 | 19946 | 17484 | -2.874 | -0.3710 | Yes | ||
138 | RPS19 | 5398 | 17490 | -2.882 | -0.3574 | Yes | ||
139 | NDUFA7 | 12347 | 17595 | -3.072 | -0.3483 | Yes | ||
140 | NDUFS2 | 4089 13760 | 17608 | -3.085 | -0.3342 | Yes | ||
141 | NDUFA8 | 14605 | 17673 | -3.259 | -0.3221 | Yes | ||
142 | RPL27A | 11181 6467 18130 | 17705 | -3.332 | -0.3078 | Yes | ||
143 | COX7B | 7260 | 17731 | -3.397 | -0.2929 | Yes | ||
144 | NDUFA10 | 7420 | 17735 | -3.403 | -0.2767 | Yes | ||
145 | NDUFB3 | 12362 | 17752 | -3.437 | -0.2611 | Yes | ||
146 | MDH2 | 9399 | 17839 | -3.673 | -0.2482 | Yes | ||
147 | NDUFA9 | 12288 | 17848 | -3.704 | -0.2309 | Yes | ||
148 | RPS24 | 5399 | 17906 | -3.903 | -0.2153 | Yes | ||
149 | SEC61B | 12305 7266 | 17938 | -4.001 | -0.1978 | Yes | ||
150 | RPL14 | 19267 | 17960 | -4.073 | -0.1794 | Yes | ||
151 | SSR2 | 15549 | 17989 | -4.162 | -0.1610 | Yes | ||
152 | SDHD | 19125 | 18022 | -4.265 | -0.1423 | Yes | ||
153 | NDUFV1 | 23953 | 18063 | -4.450 | -0.1232 | Yes | ||
154 | SLC30A7 | 15186 | 18085 | -4.530 | -0.1026 | Yes | ||
155 | RPL38 | 12562 20606 7475 | 18200 | -4.955 | -0.0850 | Yes | ||
156 | CYCS | 8821 | 18278 | -5.207 | -0.0643 | Yes | ||
157 | ATP5G1 | 8636 | 18339 | -5.580 | -0.0408 | Yes | ||
158 | UQCR | 12382 | 18358 | -5.672 | -0.0146 | Yes | ||
159 | IDH3A | 19447 | 18394 | -5.954 | 0.0120 | Yes |