Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
| Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
| Upregulated in class | transDMpreB |
| GeneSet | DNA_DEPENDENT_DNA_REPLICATION |
| Enrichment Score (ES) | 0.80179626 |
| Normalized Enrichment Score (NES) | 1.7313687 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.009171967 |
| FWER p-Value | 0.041 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ATR | 19349 | 268 | 5.616 | 0.0548 | Yes | ||
| 2 | MLH1 | 18982 | 353 | 5.103 | 0.1132 | Yes | ||
| 3 | GTPBP4 | 21548 | 370 | 4.995 | 0.1739 | Yes | ||
| 4 | MCM3 | 13991 | 372 | 4.986 | 0.2353 | Yes | ||
| 5 | TIPIN | 3013 7258 | 386 | 4.919 | 0.2952 | Yes | ||
| 6 | MSH2 | 23138 | 583 | 4.074 | 0.3349 | Yes | ||
| 7 | RPA1 | 20349 | 648 | 3.903 | 0.3795 | Yes | ||
| 8 | RFC4 | 1735 22627 | 670 | 3.827 | 0.4256 | Yes | ||
| 9 | RFC1 | 16527 | 696 | 3.717 | 0.4700 | Yes | ||
| 10 | PRIM1 | 19847 | 719 | 3.648 | 0.5138 | Yes | ||
| 11 | GMNN | 21513 | 749 | 3.568 | 0.5562 | Yes | ||
| 12 | RPA2 | 2330 16057 | 895 | 3.168 | 0.5875 | Yes | ||
| 13 | CDT1 | 18437 | 1080 | 2.756 | 0.6115 | Yes | ||
| 14 | MSH6 | 23137 5120 | 1112 | 2.697 | 0.6431 | Yes | ||
| 15 | PMS2 | 16632 | 1148 | 2.641 | 0.6738 | Yes | ||
| 16 | CDK2AP1 | 8858 | 1332 | 2.346 | 0.6928 | Yes | ||
| 17 | POLG2 | 20180 | 1333 | 2.345 | 0.7217 | Yes | ||
| 18 | CDK2 | 3438 3373 19592 3322 | 1447 | 2.143 | 0.7421 | Yes | ||
| 19 | S100A11 | 9771 | 1459 | 2.125 | 0.7677 | Yes | ||
| 20 | ORC5L | 11173 3595 | 1726 | 1.738 | 0.7748 | Yes | ||
| 21 | REV3L | 20050 | 2002 | 1.401 | 0.7772 | Yes | ||
| 22 | RFC3 | 12786 | 2067 | 1.318 | 0.7900 | Yes | ||
| 23 | MUTYH | 2400 7693 | 2132 | 1.233 | 0.8018 | Yes | ||
| 24 | MSH3 | 5119 | 2616 | 0.814 | 0.7858 | No | ||
| 25 | CDC6 | 6221 6220 | 4074 | 0.180 | 0.7096 | No | ||
| 26 | PMS1 | 13958 | 4098 | 0.176 | 0.7105 | No | ||
| 27 | NF2 | 1222 5166 | 4260 | 0.157 | 0.7038 | No | ||
| 28 | ABL1 | 2693 4301 2794 | 4314 | 0.151 | 0.7028 | No | ||
| 29 | ORC4L | 11172 6460 | 4571 | 0.126 | 0.6905 | No | ||
| 30 | GLI2 | 13859 | 4996 | 0.097 | 0.6689 | No | ||
| 31 | RAD51 | 2897 14903 | 5044 | 0.094 | 0.6675 | No | ||
| 32 | NBN | 2485 16268 2408 | 5101 | 0.090 | 0.6656 | No | ||
| 33 | CDC45L | 22642 1752 | 6568 | 0.043 | 0.5872 | No | ||
| 34 | EREG | 4679 16797 | 6648 | 0.041 | 0.5835 | No | ||
| 35 | TFAM | 19739 3330 | 6922 | 0.036 | 0.5692 | No | ||
| 36 | HMGB2 | 13594 | 8194 | 0.017 | 0.5010 | No | ||
| 37 | GLI1 | 19605 | 9456 | 0.001 | 0.4331 | No | ||
| 38 | POLA1 | 24112 | 9653 | -0.002 | 0.4225 | No | ||
| 39 | PURA | 9670 | 10677 | -0.015 | 0.3676 | No | ||
| 40 | WRNIP1 | 21675 3161 | 13226 | -0.069 | 0.2313 | No | ||
| 41 | RAD9A | 913 3674 910 23958 | 14697 | -0.184 | 0.1544 | No | ||
| 42 | ORC2L | 385 13949 | 15082 | -0.255 | 0.1368 | No | ||
| 43 | EXO1 | 14035 4135 | 15128 | -0.263 | 0.1377 | No | ||
| 44 | RAD17 | 21366 | 15569 | -0.410 | 0.1190 | No | ||
| 45 | MSH5 | 23010 1599 | 15631 | -0.435 | 0.1211 | No | ||
| 46 | ORC1L | 327 16144 | 15769 | -0.497 | 0.1198 | No | ||
| 47 | POLB | 9599 | 17541 | -2.711 | 0.0579 | No |
