Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
Upregulated in class | WTpreB |
GeneSet | V$OCT1_B |
Enrichment Score (ES) | -0.6424456 |
Normalized Enrichment Score (NES) | -1.6778848 |
Nominal p-value | 0.0 |
FDR q-value | 0.02740952 |
FWER p-Value | 0.067 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PPARGC1B | 9318 | 487 | 4.498 | 0.0005 | No | ||
2 | CD86 | 1660 22601 | 798 | 3.433 | 0.0042 | No | ||
3 | SERTAD4 | 13715 | 850 | 3.294 | 0.0211 | No | ||
4 | CDK2 | 3438 3373 19592 3322 | 1447 | 2.143 | 0.0016 | No | ||
5 | ITPR3 | 9195 | 1716 | 1.746 | -0.0025 | No | ||
6 | PIM2 | 5249 9564 9565 | 1802 | 1.644 | 0.0027 | No | ||
7 | TSGA14 | 17194 | 1868 | 1.582 | 0.0086 | No | ||
8 | BAT2 | 23006 | 1972 | 1.436 | 0.0116 | No | ||
9 | E2F3 | 21500 8874 | 2288 | 1.048 | 0.0008 | No | ||
10 | BLNK | 23681 3691 | 2670 | 0.771 | -0.0153 | No | ||
11 | NR1D1 | 4650 20258 949 | 2741 | 0.711 | -0.0148 | No | ||
12 | ATF7IP | 12028 13038 | 2763 | 0.694 | -0.0118 | No | ||
13 | NR6A1 | 14596 | 2796 | 0.662 | -0.0096 | No | ||
14 | IFIT2 | 23880 | 3103 | 0.463 | -0.0234 | No | ||
15 | SRF | 22961 1597 | 3107 | 0.457 | -0.0209 | No | ||
16 | HIST2H2AC | 6650 | 3219 | 0.403 | -0.0245 | No | ||
17 | BCL2 | 8651 3928 13864 4435 981 4062 13863 4027 | 3317 | 0.365 | -0.0276 | No | ||
18 | TWIST1 | 21291 | 3357 | 0.347 | -0.0276 | No | ||
19 | COL25A1 | 8056 1837 1844 1915 13376 | 3618 | 0.268 | -0.0401 | No | ||
20 | TBR1 | 83 | 3653 | 0.260 | -0.0404 | No | ||
21 | SP6 | 8178 13678 13679 | 3799 | 0.228 | -0.0469 | No | ||
22 | LRRTM4 | 17405 | 3907 | 0.209 | -0.0515 | No | ||
23 | RGL1 | 9723 4072 | 4129 | 0.173 | -0.0624 | No | ||
24 | PTHLH | 16931 | 4171 | 0.167 | -0.0636 | No | ||
25 | BCDO2 | 19124 | 4194 | 0.164 | -0.0639 | No | ||
26 | TSC1 | 7235 | 4257 | 0.157 | -0.0663 | No | ||
27 | TMOD2 | 6946 | 4492 | 0.133 | -0.0782 | No | ||
28 | MID1 | 5097 5098 | 4512 | 0.131 | -0.0784 | No | ||
29 | LRCH4 | 10544 6090 | 4694 | 0.116 | -0.0876 | No | ||
30 | HOXA13 | 9107 | 4764 | 0.112 | -0.0906 | No | ||
31 | CYR61 | 9159 15145 9311 5024 | 4769 | 0.111 | -0.0902 | No | ||
32 | CDX4 | 24273 | 4818 | 0.108 | -0.0921 | No | ||
33 | SCOC | 3821 12106 | 4853 | 0.106 | -0.0934 | No | ||
34 | SOX2 | 9849 15612 | 4978 | 0.098 | -0.0995 | No | ||
35 | MGAT5B | 20584 11197 | 5060 | 0.093 | -0.1033 | No | ||
36 | CPD | 20344 4556 | 5132 | 0.089 | -0.1067 | No | ||
37 | FES | 17779 3949 | 5137 | 0.089 | -0.1063 | No | ||
38 | ALDH1A1 | 8569 | 5274 | 0.082 | -0.1132 | No | ||
39 | TCF2 | 1395 20727 | 5297 | 0.081 | -0.1139 | No | ||
40 | SFRP2 | 15564 | 5301 | 0.081 | -0.1136 | No | ||
41 | SKIL | 15617 | 5335 | 0.079 | -0.1149 | No | ||
42 | ITSN1 | 9196 | 5649 | 0.066 | -0.1315 | No | ||
43 | ADORA2A | 8557 | 5659 | 0.066 | -0.1316 | No | ||
44 | VSNL1 | 6527 | 5704 | 0.064 | -0.1336 | No | ||
45 | PRKG1 | 5289 | 6114 | 0.053 | -0.1555 | No | ||
46 | FGF14 | 21716 3005 3463 | 6182 | 0.051 | -0.1588 | No | ||
47 | BDNF | 14926 2797 | 6224 | 0.050 | -0.1608 | No | ||
48 | ALK | 8574 | 6231 | 0.050 | -0.1608 | No | ||
49 | SILV | 16130 | 6446 | 0.045 | -0.1721 | No | ||
50 | CSMD3 | 10735 7938 | 6532 | 0.044 | -0.1765 | No | ||
51 | CSF3 | 1394 20671 | 6539 | 0.043 | -0.1765 | No | ||
52 | HIST1H3C | 13633 | 6708 | 0.040 | -0.1854 | No | ||
53 | HOXA10 | 17145 989 | 6757 | 0.039 | -0.1878 | No | ||
54 | PRRX1 | 9595 5271 | 6848 | 0.037 | -0.1924 | No | ||
55 | RRM2B | 6902 6903 11801 | 6928 | 0.036 | -0.1965 | No | ||
56 | STAG1 | 5520 9905 2987 | 7002 | 0.035 | -0.2003 | No | ||
57 | NEUROD6 | 17138 | 7093 | 0.033 | -0.2050 | No | ||
58 | MRAS | 9409 | 7134 | 0.032 | -0.2069 | No | ||
59 | TCEAL1 | 24245 | 7234 | 0.031 | -0.2121 | No | ||
60 | EHF | 4657 | 7731 | 0.023 | -0.2389 | No | ||
61 | SYNPR | 22094 | 7781 | 0.022 | -0.2414 | No | ||
62 | FSTL5 | 10018 | 7817 | 0.022 | -0.2432 | No | ||
63 | SLC1A2 | 5453 | 8035 | 0.019 | -0.2548 | No | ||
64 | IRX4 | 11944 | 8120 | 0.018 | -0.2593 | No | ||
65 | NXPH1 | 17524 | 8202 | 0.017 | -0.2636 | No | ||
66 | TBXAS1 | 17480 1105 | 8272 | 0.016 | -0.2672 | No | ||
67 | RGS13 | 13811 | 8303 | 0.015 | -0.2688 | No | ||
68 | CNNM4 | 14273 | 8384 | 0.014 | -0.2730 | No | ||
69 | FBXO24 | 12918 3649 | 8416 | 0.014 | -0.2746 | No | ||
70 | GNB3 | 9027 | 8548 | 0.012 | -0.2817 | No | ||
71 | KLF12 | 4960 2637 21732 9228 | 8710 | 0.010 | -0.2903 | No | ||
72 | CDH13 | 4506 3826 | 8740 | 0.009 | -0.2919 | No | ||
73 | LIPG | 23407 | 8800 | 0.009 | -0.2950 | No | ||
74 | FGF12 | 1723 22621 | 8850 | 0.008 | -0.2976 | No | ||
75 | LPL | 9283 5003 | 8994 | 0.007 | -0.3053 | No | ||
76 | SH3GL3 | 18201 | 9088 | 0.005 | -0.3104 | No | ||
77 | WNT6 | 5881 | 9202 | 0.004 | -0.3165 | No | ||
78 | DLGAP4 | 2950 10461 | 9307 | 0.003 | -0.3221 | No | ||
79 | OLIG3 | 20084 | 9359 | 0.002 | -0.3248 | No | ||
80 | DNAH5 | 8470 | 9363 | 0.002 | -0.3250 | No | ||
81 | PCDH20 | 5780 | 9370 | 0.002 | -0.3253 | No | ||
82 | MBIP | 21063 2072 | 9602 | -0.002 | -0.3378 | No | ||
83 | NRXN3 | 2153 5196 | 9658 | -0.002 | -0.3408 | No | ||
84 | SLC24A1 | 19080 | 9727 | -0.003 | -0.3445 | No | ||
85 | LYN | 16281 | 9750 | -0.003 | -0.3457 | No | ||
86 | KIF13A | 21475 | 9848 | -0.005 | -0.3509 | No | ||
87 | GPR4 | 18364 | 9928 | -0.006 | -0.3551 | No | ||
88 | PAX6 | 5223 | 10181 | -0.009 | -0.3688 | No | ||
89 | LDB2 | 16538 4989 | 10221 | -0.009 | -0.3708 | No | ||
90 | NRAS | 5191 | 10314 | -0.010 | -0.3758 | No | ||
91 | NRL | 9484 | 10445 | -0.012 | -0.3827 | No | ||
92 | LHX6 | 9275 2914 | 10689 | -0.015 | -0.3958 | No | ||
93 | SLC19A3 | 8152 | 10788 | -0.017 | -0.4010 | No | ||
94 | UPK3A | 22401 | 11090 | -0.021 | -0.4172 | No | ||
95 | EPHB3 | 22816 | 11483 | -0.027 | -0.4384 | No | ||
96 | PRDM1 | 19775 3337 | 11762 | -0.032 | -0.4532 | No | ||
97 | MITF | 17349 | 11768 | -0.032 | -0.4533 | No | ||
98 | NFIA | 16172 5170 | 11870 | -0.034 | -0.4586 | No | ||
99 | SATB2 | 5604 | 11899 | -0.034 | -0.4599 | No | ||
100 | OTX2 | 9519 | 11917 | -0.035 | -0.4606 | No | ||
101 | HIST1H2AC | 6648 | 11960 | -0.035 | -0.4627 | No | ||
102 | SPRR2B | 9869 | 11963 | -0.035 | -0.4626 | No | ||
103 | LRRN1 | 17343 | 12010 | -0.036 | -0.4649 | No | ||
104 | SLC6A15 | 8335 3321 | 12128 | -0.039 | -0.4710 | No | ||
105 | DPYSL3 | 10252 | 12360 | -0.044 | -0.4833 | No | ||
106 | CRISP1 | 22980 | 12542 | -0.049 | -0.4928 | No | ||
107 | PCYT1B | 24289 | 12686 | -0.053 | -0.5002 | No | ||
108 | NRXN1 | 1581 1575 22875 | 12942 | -0.059 | -0.5137 | No | ||
109 | EAF2 | 1727 8383 | 12956 | -0.060 | -0.5141 | No | ||
110 | PIPOX | 20340 | 13087 | -0.064 | -0.5208 | No | ||
111 | ADORA1 | 13831 | 13201 | -0.068 | -0.5265 | No | ||
112 | GPC4 | 24153 | 13224 | -0.069 | -0.5273 | No | ||
113 | HOXC5 | 22340 | 13250 | -0.070 | -0.5282 | No | ||
114 | HOXB6 | 20688 | 13340 | -0.074 | -0.5326 | No | ||
115 | COL23A1 | 10696 | 13483 | -0.079 | -0.5398 | No | ||
116 | POU2F3 | 9602 | 13549 | -0.083 | -0.5428 | No | ||
117 | SLITRK6 | 21724 | 13944 | -0.108 | -0.5636 | No | ||
118 | TLL2 | 23680 | 14068 | -0.116 | -0.5696 | No | ||
119 | PFKFB1 | 9552 | 14081 | -0.117 | -0.5695 | No | ||
120 | GAB2 | 1821 18184 2025 | 14159 | -0.123 | -0.5730 | No | ||
121 | GPRC5B | 17662 | 14187 | -0.126 | -0.5737 | No | ||
122 | CLCA3 | 6224 | 14191 | -0.126 | -0.5731 | No | ||
123 | CDX2 | 16289 | 14431 | -0.150 | -0.5851 | No | ||
124 | KCNN3 | 15538 1913 | 14448 | -0.151 | -0.5851 | No | ||
125 | ASCL3 | 17681 | 14457 | -0.152 | -0.5846 | No | ||
126 | RAB26 | 11609 | 14565 | -0.164 | -0.5895 | No | ||
127 | POU3F4 | 347 | 14590 | -0.168 | -0.5898 | No | ||
128 | THRA | 1447 10171 1406 | 14741 | -0.189 | -0.5968 | No | ||
129 | STAT4 | 14251 9907 | 14776 | -0.195 | -0.5974 | No | ||
130 | DMD | 24295 2647 | 14880 | -0.212 | -0.6018 | No | ||
131 | NR2C2 | 10216 | 15039 | -0.245 | -0.6089 | No | ||
132 | GPM6A | 3834 10618 | 15085 | -0.255 | -0.6098 | No | ||
133 | TRPM1 | 10846 474 9395 494 | 15142 | -0.265 | -0.6112 | No | ||
134 | ETV1 | 4688 8925 8924 | 15380 | -0.333 | -0.6221 | No | ||
135 | NEUROG1 | 21446 | 15382 | -0.333 | -0.6202 | No | ||
136 | HDAC9 | 21084 2131 | 15589 | -0.417 | -0.6289 | No | ||
137 | PDE4D | 10722 6235 | 15809 | -0.523 | -0.6376 | No | ||
138 | HPCAL4 | 16096 | 15822 | -0.525 | -0.6351 | No | ||
139 | SESN3 | 19561 | 15849 | -0.547 | -0.6333 | No | ||
140 | EGR2 | 8886 | 16019 | -0.677 | -0.6384 | Yes | ||
141 | FZD2 | 12179 | 16070 | -0.719 | -0.6368 | Yes | ||
142 | SREBF2 | 5509 | 16103 | -0.749 | -0.6341 | Yes | ||
143 | KCTD6 | 22098 | 16152 | -0.810 | -0.6318 | Yes | ||
144 | REL | 9716 | 16159 | -0.818 | -0.6273 | Yes | ||
145 | BTK | 24061 | 16235 | -0.895 | -0.6260 | Yes | ||
146 | NEDD4 | 19384 3101 | 16246 | -0.907 | -0.6211 | Yes | ||
147 | UBE2S | 17979 | 16264 | -0.933 | -0.6165 | Yes | ||
148 | GUCA1A | 22952 | 16296 | -0.964 | -0.6124 | Yes | ||
149 | HIST1H2BC | 12625 21696 | 16350 | -0.999 | -0.6093 | Yes | ||
150 | HIST1H2AB | 13652 | 16390 | -1.016 | -0.6053 | Yes | ||
151 | NDNL2 | 17804 | 16396 | -1.022 | -0.5995 | Yes | ||
152 | POLM | 20538 | 16440 | -1.057 | -0.5955 | Yes | ||
153 | BIN3 | 21969 | 16546 | -1.168 | -0.5942 | Yes | ||
154 | PIK3CD | 9563 | 16667 | -1.326 | -0.5928 | Yes | ||
155 | H3F3B | 4839 | 16705 | -1.370 | -0.5866 | Yes | ||
156 | GFI1B | 14637 | 16723 | -1.398 | -0.5792 | Yes | ||
157 | HIST1H2AH | 11414 | 16813 | -1.529 | -0.5749 | Yes | ||
158 | CRYZL1 | 1644 12385 | 16852 | -1.600 | -0.5674 | Yes | ||
159 | ARPC5 | 12580 7487 | 16948 | -1.728 | -0.5622 | Yes | ||
160 | SLC25A12 | 14562 | 17151 | -2.042 | -0.5610 | Yes | ||
161 | MAP2K6 | 20614 1414 | 17196 | -2.130 | -0.5506 | Yes | ||
162 | THRAP5 | 19701 | 17227 | -2.183 | -0.5392 | Yes | ||
163 | CSNK1E | 6570 2211 11332 | 17264 | -2.241 | -0.5277 | Yes | ||
164 | KCTD12 | 6240 | 17347 | -2.379 | -0.5180 | Yes | ||
165 | HIST1H2BB | 11417 | 17521 | -2.681 | -0.5113 | Yes | ||
166 | HIST1H2BK | 11423 | 17527 | -2.689 | -0.4955 | Yes | ||
167 | HIST1H3B | 11406 | 17585 | -2.819 | -0.4818 | Yes | ||
168 | AXUD1 | 18967 | 17650 | -2.946 | -0.4676 | Yes | ||
169 | HIST1H2BM | 11425 | 17687 | -3.039 | -0.4514 | Yes | ||
170 | CD79B | 20185 1309 | 17759 | -3.226 | -0.4360 | Yes | ||
171 | ESRRA | 23802 | 17813 | -3.410 | -0.4185 | Yes | ||
172 | SCML4 | 20042 | 17817 | -3.415 | -0.3982 | Yes | ||
173 | SH3BGRL | 24267 | 17831 | -3.462 | -0.3782 | Yes | ||
174 | HIST2H2BE | 6651 | 17861 | -3.552 | -0.3586 | Yes | ||
175 | NFYB | 5173 | 17901 | -3.676 | -0.3387 | Yes | ||
176 | FOXP1 | 4242 | 17922 | -3.738 | -0.3174 | Yes | ||
177 | RRAS | 18256 | 17988 | -3.923 | -0.2975 | Yes | ||
178 | ZHX2 | 11842 | 18038 | -4.076 | -0.2758 | Yes | ||
179 | NOTCH1 | 14649 | 18042 | -4.087 | -0.2515 | Yes | ||
180 | ARHGAP4 | 9343 | 18048 | -4.114 | -0.2272 | Yes | ||
181 | RHOB | 4411 | 18087 | -4.288 | -0.2036 | Yes | ||
182 | PTEN | 5305 | 18232 | -5.045 | -0.1813 | Yes | ||
183 | TCF12 | 10044 3125 | 18254 | -5.152 | -0.1516 | Yes | ||
184 | RHOBTB2 | 3069 6373 10902 | 18385 | -5.883 | -0.1235 | Yes | ||
185 | VPREB3 | 19984 | 18436 | -6.345 | -0.0883 | Yes | ||
186 | ACBD4 | 20637 | 18475 | -6.815 | -0.0496 | Yes | ||
187 | DUSP6 | 19891 3399 | 18611 | -9.573 | 0.0003 | Yes |