Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
| Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
| Upregulated in class | WTpreB |
| GeneSet | TCRPATHWAY |
| Enrichment Score (ES) | -0.77748185 |
| Normalized Enrichment Score (NES) | -1.6746774 |
| Nominal p-value | 0.0020491802 |
| FDR q-value | 0.057878416 |
| FWER p-Value | 0.085 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PTPN7 | 11500 | 1312 | 2.372 | -0.0318 | No | ||
| 2 | MAPK8 | 6459 | 2014 | 1.381 | -0.0470 | No | ||
| 3 | MAP2K1 | 19082 | 2547 | 0.862 | -0.0615 | No | ||
| 4 | CD3D | 19473 | 3436 | 0.320 | -0.1041 | No | ||
| 5 | FOS | 21202 | 4219 | 0.162 | -0.1436 | No | ||
| 6 | SHC1 | 9813 9812 5430 | 4421 | 0.139 | -0.1521 | No | ||
| 7 | HRAS | 4868 | 4707 | 0.115 | -0.1656 | No | ||
| 8 | ZAP70 | 14271 4042 | 6321 | 0.048 | -0.2516 | No | ||
| 9 | CALM1 | 21184 | 6893 | 0.037 | -0.2818 | No | ||
| 10 | CD3G | 19139 | 8313 | 0.015 | -0.3579 | No | ||
| 11 | CD3E | 8714 | 8903 | 0.008 | -0.3895 | No | ||
| 12 | PPP3CA | 1863 5284 | 9030 | 0.006 | -0.3962 | No | ||
| 13 | LAT | 17643 | 9183 | 0.004 | -0.4043 | No | ||
| 14 | SYT1 | 5565 | 9505 | -0.000 | -0.4216 | No | ||
| 15 | PLCG1 | 14753 | 9775 | -0.004 | -0.4360 | No | ||
| 16 | NFATC2 | 5168 2866 | 10619 | -0.014 | -0.4811 | No | ||
| 17 | SOS1 | 5476 | 10751 | -0.016 | -0.4879 | No | ||
| 18 | TRB@ | 1157 | 11556 | -0.028 | -0.5308 | No | ||
| 19 | NFATC4 | 22002 | 11666 | -0.030 | -0.5361 | No | ||
| 20 | PIK3R1 | 3170 | 11694 | -0.031 | -0.5371 | No | ||
| 21 | PIK3CA | 9562 | 13936 | -0.107 | -0.6560 | No | ||
| 22 | FYN | 3375 3395 20052 | 15076 | -0.254 | -0.7131 | No | ||
| 23 | CALM2 | 8681 | 16272 | -0.940 | -0.7621 | Yes | ||
| 24 | RASA1 | 10174 | 16303 | -0.967 | -0.7479 | Yes | ||
| 25 | NFATC3 | 5169 | 16404 | -1.032 | -0.7364 | Yes | ||
| 26 | RAF1 | 17035 | 16625 | -1.259 | -0.7276 | Yes | ||
| 27 | MAPK3 | 6458 11170 | 16645 | -1.295 | -0.7075 | Yes | ||
| 28 | RAC1 | 16302 | 16919 | -1.693 | -0.6945 | Yes | ||
| 29 | GRB2 | 20149 | 17099 | -1.953 | -0.6722 | Yes | ||
| 30 | CALM3 | 8682 | 17112 | -1.978 | -0.6405 | Yes | ||
| 31 | PPP3CB | 5285 | 17175 | -2.093 | -0.6096 | Yes | ||
| 32 | PRKCB1 | 1693 9574 | 17298 | -2.304 | -0.5785 | Yes | ||
| 33 | PPP3CC | 21763 | 17392 | -2.468 | -0.5431 | Yes | ||
| 34 | MAP2K4 | 20405 | 17452 | -2.546 | -0.5046 | Yes | ||
| 35 | PRKCA | 20174 | 17460 | -2.570 | -0.4630 | Yes | ||
| 36 | NFATC1 | 23398 1999 5167 9455 1985 1957 | 17547 | -2.734 | -0.4229 | Yes | ||
| 37 | NFKBIA | 21065 | 17794 | -3.356 | -0.3812 | Yes | ||
| 38 | RELA | 23783 | 17808 | -3.389 | -0.3265 | Yes | ||
| 39 | NFKB1 | 15160 | 17907 | -3.696 | -0.2713 | Yes | ||
| 40 | JUN | 15832 | 17929 | -3.751 | -0.2111 | Yes | ||
| 41 | VAV1 | 23173 | 18053 | -4.129 | -0.1502 | Yes | ||
| 42 | MAP3K1 | 21348 | 18225 | -4.997 | -0.0776 | Yes | ||
| 43 | LCK | 15746 | 18405 | -6.029 | 0.0114 | Yes |
