Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
| Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
| Upregulated in class | WTpreB |
| GeneSet | ST_T_CELL_SIGNAL_TRANSDUCTION |
| Enrichment Score (ES) | -0.7110459 |
| Normalized Enrichment Score (NES) | -1.5368346 |
| Nominal p-value | 0.007952286 |
| FDR q-value | 0.19168502 |
| FWER p-Value | 0.837 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | DTYMK | 5776 | 1230 | 2.487 | -0.0224 | No | ||
| 2 | NFKB2 | 23810 | 1247 | 2.464 | 0.0202 | No | ||
| 3 | FBXW7 | 1805 11928 | 2368 | 0.998 | -0.0226 | No | ||
| 4 | RASGRP2 | 9693 | 2899 | 0.586 | -0.0408 | No | ||
| 5 | CD3D | 19473 | 3436 | 0.320 | -0.0640 | No | ||
| 6 | RASGRP1 | 5360 14476 9694 | 3581 | 0.277 | -0.0669 | No | ||
| 7 | PAK4 | 17909 | 3777 | 0.232 | -0.0733 | No | ||
| 8 | PAK1 | 9527 | 4333 | 0.148 | -0.1005 | No | ||
| 9 | ITK | 4934 | 4876 | 0.104 | -0.1279 | No | ||
| 10 | CD28 | 14239 4092 | 5583 | 0.069 | -0.1647 | No | ||
| 11 | ITPKA | 14898 | 5793 | 0.061 | -0.1748 | No | ||
| 12 | NCK1 | 9447 5152 | 5996 | 0.056 | -0.1847 | No | ||
| 13 | ZAP70 | 14271 4042 | 6321 | 0.048 | -0.2013 | No | ||
| 14 | EPHB2 | 4675 2440 8910 | 6902 | 0.037 | -0.2319 | No | ||
| 15 | GRAP2 | 5113 9398 | 7076 | 0.033 | -0.2406 | No | ||
| 16 | NFAT5 | 3921 7037 12036 | 7402 | 0.028 | -0.2576 | No | ||
| 17 | PAK3 | 9528 | 7456 | 0.027 | -0.2600 | No | ||
| 18 | RASGRP4 | 6119 | 7628 | 0.025 | -0.2688 | No | ||
| 19 | LAT | 17643 | 9183 | 0.004 | -0.3524 | No | ||
| 20 | PLCG1 | 14753 | 9775 | -0.004 | -0.3841 | No | ||
| 21 | PAK7 | 14417 | 9893 | -0.005 | -0.3903 | No | ||
| 22 | SOS1 | 5476 | 10751 | -0.016 | -0.4362 | No | ||
| 23 | CBL | 19154 | 11843 | -0.033 | -0.4943 | No | ||
| 24 | CTLA4 | 14238 | 13463 | -0.078 | -0.5801 | No | ||
| 25 | NFKBIB | 17906 | 13596 | -0.086 | -0.5857 | No | ||
| 26 | LCP2 | 4988 9268 | 14104 | -0.118 | -0.6109 | No | ||
| 27 | ITPKB | 3963 14028 | 15245 | -0.293 | -0.6671 | No | ||
| 28 | PTPRC | 5327 9662 | 15502 | -0.380 | -0.6742 | No | ||
| 29 | DAG1 | 18996 8837 | 16074 | -0.727 | -0.6921 | No | ||
| 30 | NFKBIL1 | 23002 | 16426 | -1.049 | -0.6926 | Yes | ||
| 31 | RAF1 | 17035 | 16625 | -1.259 | -0.6810 | Yes | ||
| 32 | PAK2 | 10310 5875 | 16671 | -1.335 | -0.6599 | Yes | ||
| 33 | SOS2 | 21049 | 16958 | -1.731 | -0.6448 | Yes | ||
| 34 | RASGRP3 | 10767 | 17096 | -1.946 | -0.6179 | Yes | ||
| 35 | GRB2 | 20149 | 17099 | -1.953 | -0.5836 | Yes | ||
| 36 | NFKBIA | 21065 | 17794 | -3.356 | -0.5618 | Yes | ||
| 37 | NFKB1 | 15160 | 17907 | -3.696 | -0.5027 | Yes | ||
| 38 | VAV1 | 23173 | 18053 | -4.129 | -0.4378 | Yes | ||
| 39 | CSK | 8805 | 18265 | -5.201 | -0.3575 | Yes | ||
| 40 | LCK | 15746 | 18405 | -6.029 | -0.2587 | Yes | ||
| 41 | NFKBIE | 23225 1556 | 18406 | -6.064 | -0.1519 | Yes | ||
| 42 | MAPK1 | 1642 11167 | 18603 | -9.259 | 0.0007 | Yes |
