Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
| Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
| Upregulated in class | WTpreB |
| GeneSet | SIG_BCR_SIGNALING_PATHWAY |
| Enrichment Score (ES) | -0.6975369 |
| Normalized Enrichment Score (NES) | -1.5272435 |
| Nominal p-value | 0.003968254 |
| FDR q-value | 0.18082148 |
| FWER p-Value | 0.885 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PDK1 | 14987 | 244 | 5.797 | 0.0658 | No | ||
| 2 | ITPR3 | 9195 | 1716 | 1.746 | 0.0104 | No | ||
| 3 | FLOT2 | 1247 8975 1430 | 2493 | 0.903 | -0.0191 | No | ||
| 4 | BLNK | 23681 3691 | 2670 | 0.771 | -0.0181 | No | ||
| 5 | ITPR1 | 17341 | 2923 | 0.571 | -0.0239 | No | ||
| 6 | BCL2 | 8651 3928 13864 4435 981 4062 13863 4027 | 3317 | 0.365 | -0.0401 | No | ||
| 7 | AKT1 | 8568 | 4184 | 0.164 | -0.0845 | No | ||
| 8 | SHC1 | 9813 9812 5430 | 4421 | 0.139 | -0.0953 | No | ||
| 9 | CR2 | 3942 13707 | 6213 | 0.051 | -0.1911 | No | ||
| 10 | AKT2 | 4365 4366 | 8327 | 0.015 | -0.3046 | No | ||
| 11 | PPP3CA | 1863 5284 | 9030 | 0.006 | -0.3423 | No | ||
| 12 | LYN | 16281 | 9750 | -0.003 | -0.3810 | No | ||
| 13 | PPP1R13B | 10211 20980 | 10457 | -0.012 | -0.4189 | No | ||
| 14 | NFATC2 | 5168 2866 | 10619 | -0.014 | -0.4273 | No | ||
| 15 | SOS1 | 5476 | 10751 | -0.016 | -0.4342 | No | ||
| 16 | PIK3R1 | 3170 | 11694 | -0.031 | -0.4845 | No | ||
| 17 | NR0B2 | 16050 | 11856 | -0.033 | -0.4927 | No | ||
| 18 | PIK3CA | 9562 | 13936 | -0.107 | -0.6032 | No | ||
| 19 | GSK3A | 405 | 14869 | -0.210 | -0.6505 | No | ||
| 20 | FLOT1 | 23249 1613 | 14922 | -0.221 | -0.6503 | No | ||
| 21 | BCR | 8478 3384 19990 | 14943 | -0.225 | -0.6483 | No | ||
| 22 | PTPRC | 5327 9662 | 15502 | -0.380 | -0.6732 | No | ||
| 23 | ITPR2 | 9194 | 15707 | -0.466 | -0.6778 | No | ||
| 24 | DAG1 | 18996 8837 | 16074 | -0.727 | -0.6876 | Yes | ||
| 25 | BTK | 24061 | 16235 | -0.895 | -0.6841 | Yes | ||
| 26 | CD22 | 17881 | 16316 | -0.978 | -0.6751 | Yes | ||
| 27 | RAF1 | 17035 | 16625 | -1.259 | -0.6745 | Yes | ||
| 28 | MAPK3 | 6458 11170 | 16645 | -1.295 | -0.6579 | Yes | ||
| 29 | PIK3CD | 9563 | 16667 | -1.326 | -0.6410 | Yes | ||
| 30 | MAP4K1 | 18313 | 16826 | -1.546 | -0.6284 | Yes | ||
| 31 | CD19 | 17640 | 16921 | -1.697 | -0.6104 | Yes | ||
| 32 | SOS2 | 21049 | 16958 | -1.731 | -0.5887 | Yes | ||
| 33 | GRB2 | 20149 | 17099 | -1.953 | -0.5697 | Yes | ||
| 34 | PPP3CB | 5285 | 17175 | -2.093 | -0.5452 | Yes | ||
| 35 | PLCG2 | 18453 | 17303 | -2.308 | -0.5206 | Yes | ||
| 36 | PPP3CC | 21763 | 17392 | -2.468 | -0.4918 | Yes | ||
| 37 | AKT3 | 13739 982 | 17441 | -2.539 | -0.4598 | Yes | ||
| 38 | NFATC1 | 23398 1999 5167 9455 1985 1957 | 17547 | -2.734 | -0.4282 | Yes | ||
| 39 | BAD | 24000 | 17607 | -2.854 | -0.3925 | Yes | ||
| 40 | INPP5D | 14198 | 17733 | -3.147 | -0.3564 | Yes | ||
| 41 | GSK3B | 22761 | 17749 | -3.186 | -0.3139 | Yes | ||
| 42 | SYK | 21636 | 17785 | -3.326 | -0.2705 | Yes | ||
| 43 | VAV1 | 23173 | 18053 | -4.129 | -0.2286 | Yes | ||
| 44 | CD81 | 8719 | 18143 | -4.545 | -0.1715 | Yes | ||
| 45 | CSK | 8805 | 18265 | -5.201 | -0.1072 | Yes | ||
| 46 | MAPK1 | 1642 11167 | 18603 | -9.259 | 0.0007 | Yes |
