Details for gene set HSA04650_NATURAL_KILLER_CELL_MEDIATED

Table: GSEA Results Summary

Dataset	Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB
Phenotype	phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	HSA04650_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY
Enrichment Score (ES)	-0.66095537
Normalized Enrichment Score (NES)	-1.5999932
Nominal p-value	0.0
FDR q-value	0.08922386
FWER p-Value	0.433

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PIK3CB	19030	489	4.489	0.0115	No
2	CD48	14051	563	4.157	0.0427	No
3	PIK3R3	5248	656	3.876	0.0704	No
4	HCST	6237	1464	2.109	0.0447	No
5	FCER1G	13759	1722	1.741	0.0455	No
6	BID	17017 435	2337	1.007	0.0208	No
7	MAP2K1	19082	2547	0.862	0.0168	No
8	FCGR3A	8960	2982	0.537	-0.0021	No
9	CASP3	8693	3078	0.475	-0.0032	No
10	MAP2K2	19933	3294	0.375	-0.0116	No
11	IFNA14	11917	3701	0.248	-0.0314	No
12	TNFRSF10B	21971 10205 5781 10204	4004	0.192	-0.0461	No
13	PIK3R2	18850	4208	0.163	-0.0557	No
14	ITGAL	9187	4303	0.152	-0.0595	No
15	PAK1	9527	4333	0.148	-0.0598	No
16	SHC1	9813 9812 5430	4421	0.139	-0.0633	No
17	HRAS	4868	4707	0.115	-0.0778	No
18	IFNA1	9147	4892	0.103	-0.0868	No
19	PPP3R2	9612	4958	0.099	-0.0895	No
20	IFNA7	9152	5040	0.094	-0.0931	No
21	SHC3	21465	5545	0.070	-0.1197	No
22	RAC3	20561	6100	0.053	-0.1492	No
23	PIK3R5	11507	6227	0.050	-0.1555	No
24	ZAP70	14271 4042	6321	0.048	-0.1602	No
25	SH2D1B	14061	6515	0.044	-0.1702	No
26	IFNB1	15846	6703	0.040	-0.1800	No
27	KLRC1	9242	6752	0.039	-0.1822	No
28	IFNA4	9150	7125	0.033	-0.2020	No
29	KIR3DL1	2611 6365	7172	0.032	-0.2042	No
30	CD247	4498 8715	7180	0.032	-0.2044	No
31	NCR1	18409	7362	0.028	-0.2139	No
32	NFAT5	3921 7037 12036	7402	0.028	-0.2158	No
33	PRF1	20011	8226	0.017	-0.2601	No
34	PPP3CA	1863 5284	9030	0.006	-0.3034	No
35	LAT	17643	9183	0.004	-0.3115	No
36	PLCG1	14753	9775	-0.004	-0.3434	No
37	PPP3R1	9611 489	10273	-0.010	-0.3702	No
38	NRAS	5191	10314	-0.010	-0.3722	No
39	NFATC2	5168 2866	10619	-0.014	-0.3885	No
40	IFNAR1	22703	10662	-0.015	-0.3907	No
41	SOS1	5476	10751	-0.016	-0.3953	No
42	IFNA2	9149	10783	-0.017	-0.3968	No
43	KLRC3	16975	10871	-0.018	-0.4014	No
44	IFNA13	15844	11381	-0.025	-0.4286	No
45	TNFSF10	15626	11601	-0.029	-0.4402	No
46	NFATC4	22002	11666	-0.030	-0.4434	No
47	PIK3R1	3170	11694	-0.031	-0.4446	No
48	IFNA6	17749	11961	-0.035	-0.4587	No
49	GZMB	21810	12082	-0.038	-0.4648	No
50	PTPN11	5326 16391 9660	12087	-0.038	-0.4647	No
51	CSF2	20454	12281	-0.042	-0.4748	No
52	TNF	23004	12665	-0.052	-0.4950	No
53	KLRC2	9243	12821	-0.056	-0.5029	No
54	VAV3	1774 1848 15443	13236	-0.069	-0.5247	No
55	SH2D1A	9810	13637	-0.088	-0.5456	No
56	PIK3CA	9562	13936	-0.107	-0.5607	No
57	LCP2	4988 9268	14104	-0.118	-0.5688	No
58	KLRK1	6544 16976 11281	14143	-0.122	-0.5698	No
59	VAV2	5848 2670	14239	-0.130	-0.5738	No
60	FASLG	13789	14463	-0.153	-0.5846	No
61	TYROBP	18302	14544	-0.162	-0.5875	No
62	IFNA5	9151	14810	-0.200	-0.6001	No
63	ARAF	24367	14823	-0.202	-0.5991	No
64	FYN	3375 3395 20052	15076	-0.254	-0.6105	No
65	IFNG	19869	15250	-0.294	-0.6174	No
66	IFNAR2	22705 1699	15335	-0.319	-0.6192	No
67	FAS	23881 3750	15827	-0.529	-0.6413	No
68	IFNGR1	20083	15943	-0.608	-0.6424	No
69	KLRD1	17266	16086	-0.734	-0.6438	No
70	NFATC3	5169	16404	-1.032	-0.6522	Yes
71	ITGB2	19978	16481	-1.105	-0.6470	Yes
72	RAF1	17035	16625	-1.259	-0.6441	Yes
73	MAPK3	6458 11170	16645	-1.295	-0.6342	Yes
74	PIK3CD	9563	16667	-1.326	-0.6241	Yes
75	IFNGR2	9155 22702	16815	-1.530	-0.6192	Yes
76	RAC1	16302	16919	-1.693	-0.6104	Yes
77	SOS2	21049	16958	-1.731	-0.5979	Yes
78	GRB2	20149	17099	-1.953	-0.5889	Yes
79	ICAM1	19545	17174	-2.093	-0.5752	Yes
80	PPP3CB	5285	17175	-2.093	-0.5576	Yes
81	PRKCB1	1693 9574	17298	-2.304	-0.5447	Yes
82	PLCG2	18453	17303	-2.308	-0.5254	Yes
83	PPP3CC	21763	17392	-2.468	-0.5093	Yes
84	PRKCA	20174	17460	-2.570	-0.4913	Yes
85	NFATC1	23398 1999 5167 9455 1985 1957	17547	-2.734	-0.4728	Yes
86	SH3BP2	16874	17663	-2.971	-0.4540	Yes
87	SYK	21636	17785	-3.326	-0.4324	Yes
88	VAV1	23173	18053	-4.129	-0.4120	Yes
89	ICAM2	20183	18110	-4.383	-0.3780	Yes
90	PTK2B	21776	18273	-5.239	-0.3425	Yes
91	RAC2	22217	18374	-5.782	-0.2991	Yes
92	LCK	15746	18405	-6.029	-0.2498	Yes
93	KRAS	9247	18444	-6.421	-0.1976	Yes
94	PTPN6	17002	18509	-7.257	-0.1398	Yes
95	PIK3CG	6635	18554	-7.967	-0.0749	Yes
96	MAPK1	1642 11167	18603	-9.259	0.0007	Yes