Details for gene set HSA04630_JAK_STAT_SIGNALING

Table: GSEA Results Summary

Dataset	Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB
Phenotype	phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	HSA04630_JAK_STAT_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.60485446
Normalized Enrichment Score (NES)	-1.5315245
Nominal p-value	0.0044247787
FDR q-value	0.18042025
FWER p-Value	0.868

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CCND1	4487 4488 8707 17535	25	9.348	0.0686	No
2	PIK3CB	19030	489	4.489	0.0771	No
3	PIK3R3	5248	656	3.876	0.0972	No
4	SOCS2	5694	883	3.192	0.1088	No
5	IL10	14145 1510 1553 22902	1820	1.629	0.0704	No
6	IL12RB1	3916 18582	2452	0.937	0.0432	No
7	STAM2	7095 2845	2793	0.665	0.0298	No
8	IL2RB	22219	3098	0.465	0.0168	No
9	IL6ST	4920	3188	0.416	0.0151	No
10	IL6R	1862 4919	3230	0.397	0.0159	No
11	IL9R	20505	3410	0.327	0.0087	No
12	IFNA14	11917	3701	0.248	-0.0052	No
13	TYK2	12058 19215	3748	0.238	-0.0059	No
14	IL15RA	2899 2717 15118 2792	3805	0.227	-0.0072	No
15	IL4	9174	3912	0.208	-0.0114	No
16	IL24	976 13841	3923	0.206	-0.0104	No
17	IL15	18826 3801	4142	0.172	-0.0209	No
18	AKT1	8568	4184	0.164	-0.0219	No
19	PIK3R2	18850	4208	0.163	-0.0219	No
20	SPRED2	8539 4332	4420	0.139	-0.0323	No
21	STAT5A	20664	4510	0.131	-0.0361	No
22	IFNA1	9147	4892	0.103	-0.0560	No
23	IL5	20884 10220	5008	0.096	-0.0615	No
24	IFNA7	9152	5040	0.094	-0.0624	No
25	SPRY1	15606 1901	5908	0.058	-0.1089	No
26	CSF2RA	23631	5925	0.058	-0.1093	No
27	CNTFR	2515 15906	5947	0.057	-0.1101	No
28	IL6	16895	6126	0.053	-0.1193	No
29	PIK3R5	11507	6227	0.050	-0.1243	No
30	CSF3	1394 20671	6539	0.043	-0.1408	No
31	SPRY4	23448	6615	0.042	-0.1446	No
32	IFNB1	15846	6703	0.040	-0.1490	No
33	IL19	13839	6913	0.036	-0.1600	No
34	IL3	20453	6994	0.035	-0.1641	No
35	EPO	8911	6998	0.035	-0.1640	No
36	TPO	21092	7011	0.035	-0.1644	No
37	IFNA4	9150	7125	0.033	-0.1702	No
38	IFNK	11837	7302	0.030	-0.1795	No
39	IL13	20461	7370	0.028	-0.1830	No
40	IL23R	17127	7448	0.027	-0.1869	No
41	IL22RA1	16037	7715	0.023	-0.2011	No
42	CNTF	3741 8761 3680 3736	7809	0.022	-0.2060	No
43	AKT2	4365 4366	8327	0.015	-0.2339	No
44	CBLC	17938	8588	0.012	-0.2478	No
45	IL9	21444	8717	0.010	-0.2547	No
46	IL12B	20918	8911	0.007	-0.2651	No
47	GHR	22336	8939	0.007	-0.2665	No
48	IFNE1	15842	9356	0.002	-0.2890	No
49	IL5RA	17051	9451	0.001	-0.2941	No
50	IL11	17981	9890	-0.005	-0.3177	No
51	SOCS7	5308 20679	9964	-0.006	-0.3216	No
52	STAT5B	20222	10037	-0.007	-0.3255	No
53	IL22RA2	20082	10072	-0.008	-0.3272	No
54	LEPR	2531 2349	10090	-0.008	-0.3281	No
55	IL20	13840	10097	-0.008	-0.3284	No
56	MPL	15780	10175	-0.009	-0.3325	No
57	IL22	11948	10470	-0.013	-0.3483	No
58	IL13RA2	24036	10567	-0.014	-0.3534	No
59	IFNAR1	22703	10662	-0.015	-0.3583	No
60	SOS1	5476	10751	-0.016	-0.3630	No
61	IL13RA1	24361	10779	-0.017	-0.3643	No
62	IFNA2	9149	10783	-0.017	-0.3644	No
63	LEP	17505	10909	-0.019	-0.3710	No
64	PRL	21690	11180	-0.022	-0.3854	No
65	IFNA13	15844	11381	-0.025	-0.3961	No
66	TSLP	23604 1955	11419	-0.026	-0.3979	No
67	IL21	12241	11629	-0.029	-0.4089	No
68	PIK3R1	3170	11694	-0.031	-0.4122	No
69	CTF1	18064	11814	-0.033	-0.4184	No
70	CBL	19154	11843	-0.033	-0.4196	No
71	IFNA6	17749	11961	-0.035	-0.4257	No
72	IL7	4921	11984	-0.036	-0.4266	No
73	IL12RB2	17128	12000	-0.036	-0.4272	No
74	PTPN11	5326 16391 9660	12087	-0.038	-0.4315	No
75	CSF2	20454	12281	-0.042	-0.4417	No
76	IL2	15354	12608	-0.050	-0.4589	No
77	SPRY2	21725	12763	-0.054	-0.4669	No
78	LIF	956 667 20960	12854	-0.056	-0.4713	No
79	PIAS2	1948 5102	12912	-0.058	-0.4740	No
80	IL23A	19598	12995	-0.061	-0.4779	No
81	LIFR	22515 9277	13042	-0.063	-0.4800	No
82	OSMR	22333	13150	-0.066	-0.4853	No
83	EPOR	19204	13643	-0.088	-0.5112	No
84	PIK3CA	9562	13936	-0.107	-0.5262	No
85	SOCS5	1619 23141	14043	-0.114	-0.5311	No
86	JAK2	23893 9197 3706	14343	-0.140	-0.5462	No
87	STAT6	19854 9909	14362	-0.141	-0.5461	No
88	IL28RA	10823 16038	14393	-0.144	-0.5467	No
89	IL21R	1398 18084	14492	-0.155	-0.5508	No
90	STAT4	14251 9907	14776	-0.195	-0.5647	No
91	IFNA5	9151	14810	-0.200	-0.5650	No
92	SPRED1	4331	14947	-0.225	-0.5706	No
93	IL2RG	24096	14951	-0.226	-0.5691	No
94	MYC	22465 9435	14983	-0.233	-0.5690	No
95	JAK3	9198 4936	15055	-0.249	-0.5710	No
96	SOCS4	7424	15229	-0.288	-0.5782	No
97	IFNG	19869	15250	-0.294	-0.5771	No
98	SOCS3	20131	15281	-0.304	-0.5765	No
99	CLCF1	12160 3742	15289	-0.306	-0.5745	No
100	IFNAR2	22705 1699	15335	-0.319	-0.5746	No
101	CSF3R	8804 8803 2326 4565	15501	-0.380	-0.5807	No
102	PRLR	9620 5291	15864	-0.551	-0.5961	No
103	IFNGR1	20083	15943	-0.608	-0.5958	No
104	JAK1	15827	16111	-0.760	-0.5992	Yes
105	CRLF2	16442	16134	-0.788	-0.5945	Yes
106	PIAS4	19681	16292	-0.960	-0.5958	Yes
107	PIAS3	15491 672 1906	16421	-1.044	-0.5949	Yes
108	IL3RA	22091	16439	-1.057	-0.5879	Yes
109	PIK3CD	9563	16667	-1.326	-0.5903	Yes
110	STAM	2912 15117	16814	-1.529	-0.5867	Yes
111	IFNGR2	9155 22702	16815	-1.530	-0.5753	Yes
112	SOS2	21049	16958	-1.731	-0.5700	Yes
113	IL10RA	19137	16984	-1.766	-0.5581	Yes
114	CCND2	16987	17040	-1.850	-0.5473	Yes
115	GRB2	20149	17099	-1.953	-0.5358	Yes
116	STAT2	19840	17120	-1.990	-0.5220	Yes
117	CISH	8743	17180	-2.104	-0.5094	Yes
118	IL4R	18085	17270	-2.250	-0.4974	Yes
119	PIM1	23308	17289	-2.292	-0.4812	Yes
120	IL10RB	9169	17406	-2.493	-0.4688	Yes
121	AKT3	13739 982	17441	-2.539	-0.4517	Yes
122	CREBBP	22682 8783	17516	-2.659	-0.4358	Yes
123	CCND3	4489 4490	17589	-2.825	-0.4185	Yes
124	SOCS1	4522	17909	-3.698	-0.4081	Yes
125	IL2RA	4918	18055	-4.139	-0.3850	Yes
126	PIAS1	7126	18126	-4.458	-0.3554	Yes
127	CBLB	5531 22734	18286	-5.302	-0.3244	Yes
128	IL12A	4913	18294	-5.328	-0.2849	Yes
129	BCL2L1	4440 2930 8652	18346	-5.613	-0.2456	Yes
130	STAT1	3936 5524	18359	-5.675	-0.2038	Yes
131	STAT3	5525 9906	18377	-5.818	-0.1612	Yes
132	PTPN6	17002	18509	-7.257	-0.1140	Yes
133	PIK3CG	6635	18554	-7.967	-0.0567	Yes
134	IL7R	9175 4922	18559	-8.025	0.0031	Yes