Details for gene set HSA00230_PURINE

Table: GSEA Results Summary

Dataset	Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB
Phenotype	phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB
Upregulated in class	transDMpreB
GeneSet	HSA00230_PURINE_METABOLISM
Enrichment Score (ES)	0.6750062
Normalized Enrichment Score (NES)	1.6808797
Nominal p-value	0.0
FDR q-value	0.030098615
FWER p-Value	0.076

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	POLR1B	14857	9	10.065	0.0375	Yes
2	APRT	8620	44	8.604	0.0681	Yes
3	NME2	9468	49	8.321	0.0992	Yes
4	NME1	9467	68	7.855	0.1279	Yes
5	IMPDH2	10730	69	7.844	0.1575	Yes
6	POLD2	20537	78	7.693	0.1861	Yes
7	ADA	2703 14361	89	7.521	0.2139	Yes
8	PPAT	6081	93	7.493	0.2420	Yes
9	POLE	16755	111	7.095	0.2678	Yes
10	ATIC	14231 3968	130	6.917	0.2929	Yes
11	NME4	23065 1577	165	6.514	0.3157	Yes
12	PDE6D	13897 3945	174	6.436	0.3395	Yes
13	GUK1	20432	179	6.377	0.3633	Yes
14	ADSL	4358	181	6.342	0.3872	Yes
15	NUDT5	15121	183	6.323	0.4110	Yes
16	PAICS	16820	226	5.909	0.4310	Yes
17	POLE3	7200	276	5.588	0.4494	Yes
18	POLR2H	10888	296	5.463	0.4690	Yes
19	NME6	3139 19297	352	5.107	0.4853	Yes
20	RRM1	18163	391	4.897	0.5017	Yes
21	POLA2	23988	396	4.885	0.5199	Yes
22	ENTPD4	7449	455	4.622	0.5342	Yes
23	NUDT9	7897	482	4.521	0.5498	Yes
24	RFC5	13005 7791	568	4.143	0.5609	Yes
25	GMPS	15578	598	4.048	0.5746	Yes
26	GART	22543 1754	706	3.684	0.5827	Yes
27	PRIM1	19847	719	3.648	0.5958	Yes
28	POLD3	17742	746	3.578	0.6079	Yes
29	NT5M	8345 4175	778	3.508	0.6194	Yes
30	POLR2J	16672	793	3.452	0.6317	Yes
31	PRPS1	24233	811	3.405	0.6436	Yes
32	NUDT2	16239	1174	2.584	0.6338	Yes
33	PDE8A	18202	1273	2.426	0.6376	Yes
34	POLR3H	13460 8135	1275	2.423	0.6467	Yes
35	POLR3A	21900	1307	2.378	0.6540	Yes
36	POLR2K	9413	1342	2.339	0.6610	Yes
37	PKM2	3642 9573	1435	2.171	0.6642	Yes
38	RRM2	5401 5400	1481	2.084	0.6696	Yes
39	PRPS2	24003	1523	2.022	0.6750	Yes
40	HPRT1	2655 24339 408	1927	1.506	0.6589	No
41	IMPDH1	17197 1131	1971	1.436	0.6620	No
42	POLR1A	9749 5393	2044	1.341	0.6631	No
43	POLR1D	3593 3658 16623	2342	1.005	0.6509	No
44	POLR2I	12839	2417	0.967	0.6505	No
45	ECGF1	22160	2592	0.833	0.6442	No
46	POLR2E	3325 19699	2644	0.791	0.6445	No
47	POLR2A	5394	2663	0.775	0.6464	No
48	PNPT1	20936	2768	0.688	0.6434	No
49	NT5E	19360 18702	3241	0.392	0.6193	No
50	PDE10A	23387	3325	0.363	0.6162	No
51	XDH	22897	3454	0.313	0.6105	No
52	ENTPD6	4496 2678	3839	0.221	0.5905	No
53	AK3L1	8564	4177	0.166	0.5729	No
54	AK5	6042	4178	0.166	0.5736	No
55	GUCY1A3	7216 12245 15310	5030	0.095	0.5279	No
56	ADCY4	2980 21818	5320	0.079	0.5126	No
57	AMPD2	1931 15197	5322	0.079	0.5128	No
58	GDA	4764	5663	0.066	0.4947	No
59	ITPA	9193	5988	0.056	0.4773	No
60	ENTPD3	19266	6163	0.052	0.4681	No
61	AMPD1	5051	6243	0.050	0.4640	No
62	ENTPD8	12996	6283	0.049	0.4621	No
63	PDE2A	18170	6388	0.046	0.4567	No
64	POLR3K	12447 7372	6894	0.037	0.4295	No
65	RRM2B	6902 6903 11801	6928	0.036	0.4278	No
66	PDE6G	20119	7118	0.033	0.4177	No
67	PDE5A	15431	7149	0.032	0.4162	No
68	ADCY8	22281	7337	0.029	0.4062	No
69	GUCY2F	24045	7454	0.027	0.4001	No
70	PAPSS2	6258	7461	0.027	0.3998	No
71	GUCY1A2	19580	7613	0.025	0.3918	No
72	POLE2	21053	7814	0.022	0.3810	No
73	ALLC	21093 2130	7947	0.020	0.3740	No
74	POLR2C	9750	8109	0.018	0.3653	No
75	ENTPD1	4495	8186	0.017	0.3613	No
76	NPR1	9480	8679	0.010	0.3347	No
77	PDE1A	9541 5234	8950	0.007	0.3201	No
78	POLA1	24112	9653	-0.002	0.2822	No
79	NP	22027 9597 5273 5274	9774	-0.004	0.2757	No
80	ADCY3	21329 894	9900	-0.005	0.2689	No
81	NPR2	16230	10933	-0.019	0.2132	No
82	GUCY2C	1140 16954	11013	-0.020	0.2090	No
83	CANT1	13304	11171	-0.022	0.2006	No
84	ADK	3302 3454 8555	11262	-0.023	0.1958	No
85	PKLR	1850 15545	11428	-0.026	0.1870	No
86	ENPP3	19803	11642	-0.030	0.1756	No
87	POLR3B	12875	11699	-0.031	0.1727	No
88	ENTPD2	8713	11875	-0.034	0.1633	No
89	POLR2B	16817	12062	-0.037	0.1534	No
90	AK1	4363	12129	-0.039	0.1500	No
91	PDE8B	5756	12167	-0.039	0.1481	No
92	ADCY5	10312	12495	-0.047	0.1306	No
93	PDE9A	23301	12656	-0.052	0.1222	No
94	PDE1C	5235	12675	-0.052	0.1214	No
95	PDE6H	17257	13109	-0.065	0.0982	No
96	GUCY1B3	15311	13357	-0.074	0.0851	No
97	PDE11A	10805	13526	-0.082	0.0764	No
98	PDE4A	3037 19542 3083 3023	13623	-0.087	0.0715	No
99	PDE7B	19807	13696	-0.091	0.0679	No
100	ADCY6	22139 2283 8551	13737	-0.094	0.0661	No
101	AMPD3	4383 2110	13809	-0.098	0.0627	No
102	NME7	926 4101 14070 3986 3946 931	13867	-0.102	0.0600	No
103	ADCY2	21412	14026	-0.113	0.0518	No
104	NT5C1B	21315	14066	-0.116	0.0502	No
105	PDE3B	5236	14856	-0.207	0.0083	No
106	PDE4C	8481	15676	-0.453	-0.0343	No
107	ENPP1	19804	15800	-0.517	-0.0390	No
108	PDE4D	10722 6235	15809	-0.523	-0.0375	No
109	GMPR2	2711	15865	-0.551	-0.0384	No
110	NT5C3	17136	16129	-0.777	-0.0497	No
111	PDE4B	9543	16149	-0.808	-0.0477	No
112	POLR2G	23753	16179	-0.839	-0.0461	No
113	ADCY9	22680	16314	-0.976	-0.0496	No
114	ADCY7	8552 448	16511	-1.133	-0.0560	No
115	NT5C	20151	16582	-1.203	-0.0552	No
116	GMPR	21651	16679	-1.342	-0.0553	No
117	DGUOK	17099 1041	16691	-1.355	-0.0508	No
118	AK2	8563 2479 16073	16931	-1.712	-0.0573	No
119	PAPSS1	15419	17023	-1.824	-0.0553	No
120	POLD1	17847	17042	-1.851	-0.0493	No
121	FHIT	21920	17491	-2.617	-0.0637	No
122	POLE4	12441	17502	-2.639	-0.0543	No
123	NT5C2	3768 8052	17618	-2.872	-0.0497	No
124	ZNRD1	1491 22987	17682	-3.030	-0.0416	No
125	ENTPD5	4497	17744	-3.169	-0.0330	No
126	PDE7A	9544 1788	17870	-3.580	-0.0263	No
127	DCK	16808	18181	-4.761	-0.0251	No
128	ADSSL1	21136 2087	18411	-6.116	-0.0144	No
129	POLD4	12822	18466	-6.742	0.0081	No