Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
| Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
| Upregulated in class | transDMpreB |
| GeneSet | DNA_REPLICATION_REACTOME |
| Enrichment Score (ES) | 0.77319145 |
| Normalized Enrichment Score (NES) | 1.6529386 |
| Nominal p-value | 0.004140787 |
| FDR q-value | 0.026806854 |
| FWER p-Value | 0.131 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | POLD2 | 20537 | 78 | 7.693 | 0.0639 | Yes | ||
| 2 | NACA | 9444 5147 | 105 | 7.228 | 0.1264 | Yes | ||
| 3 | POLE | 16755 | 111 | 7.095 | 0.1889 | Yes | ||
| 4 | ORC6L | 18539 | 235 | 5.854 | 0.2341 | Yes | ||
| 5 | MCM3 | 13991 | 372 | 4.986 | 0.2709 | Yes | ||
| 6 | POLA2 | 23988 | 396 | 4.885 | 0.3129 | Yes | ||
| 7 | MCM2 | 17074 | 445 | 4.703 | 0.3519 | Yes | ||
| 8 | MCM10 | 14694 | 448 | 4.697 | 0.3934 | Yes | ||
| 9 | RFC5 | 13005 7791 | 568 | 4.143 | 0.4237 | Yes | ||
| 10 | RPA1 | 20349 | 648 | 3.903 | 0.4539 | Yes | ||
| 11 | RFC4 | 1735 22627 | 670 | 3.827 | 0.4867 | Yes | ||
| 12 | RFC1 | 16527 | 696 | 3.717 | 0.5182 | Yes | ||
| 13 | PRIM1 | 19847 | 719 | 3.648 | 0.5493 | Yes | ||
| 14 | POLD3 | 17742 | 746 | 3.578 | 0.5796 | Yes | ||
| 15 | GMNN | 21513 | 749 | 3.568 | 0.6110 | Yes | ||
| 16 | PRIM2A | 13986 | 834 | 3.346 | 0.6361 | Yes | ||
| 17 | MCM5 | 18564 | 842 | 3.327 | 0.6652 | Yes | ||
| 18 | RPA2 | 2330 16057 | 895 | 3.168 | 0.6904 | Yes | ||
| 19 | RPA3 | 12667 | 932 | 3.065 | 0.7156 | Yes | ||
| 20 | CDT1 | 18437 | 1080 | 2.756 | 0.7321 | Yes | ||
| 21 | PCNA | 9535 | 1127 | 2.676 | 0.7533 | Yes | ||
| 22 | CDK2 | 3438 3373 19592 3322 | 1447 | 2.143 | 0.7551 | Yes | ||
| 23 | MCM7 | 9372 3568 | 1539 | 1.995 | 0.7678 | Yes | ||
| 24 | ORC5L | 11173 3595 | 1726 | 1.738 | 0.7732 | Yes | ||
| 25 | RFC3 | 12786 | 2067 | 1.318 | 0.7666 | No | ||
| 26 | CDC6 | 6221 6220 | 4074 | 0.180 | 0.6602 | No | ||
| 27 | ORC4L | 11172 6460 | 4571 | 0.126 | 0.6346 | No | ||
| 28 | UBB | 10240 | 6104 | 0.053 | 0.5526 | No | ||
| 29 | CDC45L | 22642 1752 | 6568 | 0.043 | 0.5280 | No | ||
| 30 | POLE2 | 21053 | 7814 | 0.022 | 0.4612 | No | ||
| 31 | UBC | 14 14 10241 15 16 | 13217 | -0.069 | 0.1710 | No | ||
| 32 | UBA52 | 10239 | 14209 | -0.128 | 0.1188 | No | ||
| 33 | ORC2L | 385 13949 | 15082 | -0.255 | 0.0741 | No | ||
| 34 | RPS27A | 13433 | 15243 | -0.292 | 0.0681 | No | ||
| 35 | ORC3L | 6941 | 15735 | -0.482 | 0.0459 | No | ||
| 36 | MCM6 | 4000 13845 4119 | 15750 | -0.489 | 0.0495 | No | ||
| 37 | ORC1L | 327 16144 | 15769 | -0.497 | 0.0529 | No | ||
| 38 | MCM4 | 22655 1708 | 16371 | -1.005 | 0.0294 | No | ||
| 39 | CDC7 | 16765 3477 | 16934 | -1.719 | 0.0144 | No | ||
| 40 | POLD1 | 17847 | 17042 | -1.851 | 0.0250 | No | ||
| 41 | POLD4 | 12822 | 18466 | -6.742 | 0.0081 | No |
