Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
| Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
| Upregulated in class | transDMpreB |
| GeneSet | REACTOME_PURINE_METABOLISM |
| Enrichment Score (ES) | 0.7834874 |
| Normalized Enrichment Score (NES) | 1.6510849 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.010860295 |
| FWER p-Value | 0.203 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | APRT | 8620 | 44 | 8.604 | 0.0678 | Yes | ||
| 2 | NME2 | 9468 | 49 | 8.321 | 0.1354 | Yes | ||
| 3 | NME1 | 9467 | 68 | 7.855 | 0.1985 | Yes | ||
| 4 | IMPDH2 | 10730 | 69 | 7.844 | 0.2624 | Yes | ||
| 5 | ADA | 2703 14361 | 89 | 7.521 | 0.3227 | Yes | ||
| 6 | PPAT | 6081 | 93 | 7.493 | 0.3836 | Yes | ||
| 7 | ATP5G1 | 8636 | 101 | 7.285 | 0.4427 | Yes | ||
| 8 | ATIC | 14231 3968 | 130 | 6.917 | 0.4976 | Yes | ||
| 9 | GUK1 | 20432 | 179 | 6.377 | 0.5470 | Yes | ||
| 10 | ADSL | 4358 | 181 | 6.342 | 0.5986 | Yes | ||
| 11 | PAICS | 16820 | 226 | 5.909 | 0.6444 | Yes | ||
| 12 | RRM1 | 18163 | 391 | 4.897 | 0.6755 | Yes | ||
| 13 | GMPS | 15578 | 598 | 4.048 | 0.6974 | Yes | ||
| 14 | GART | 22543 1754 | 706 | 3.684 | 0.7217 | Yes | ||
| 15 | ATP5A1 | 23505 | 815 | 3.395 | 0.7436 | Yes | ||
| 16 | ATP5O | 22539 | 1145 | 2.647 | 0.7474 | Yes | ||
| 17 | ATP5I | 8637 | 1283 | 2.411 | 0.7597 | Yes | ||
| 18 | RRM2 | 5401 5400 | 1481 | 2.084 | 0.7661 | Yes | ||
| 19 | ATP5J2 | 12186 | 1596 | 1.907 | 0.7755 | Yes | ||
| 20 | HPRT1 | 2655 24339 408 | 1927 | 1.506 | 0.7700 | Yes | ||
| 21 | IMPDH1 | 17197 1131 | 1971 | 1.436 | 0.7794 | Yes | ||
| 22 | TXNRD1 | 19923 | 2092 | 1.289 | 0.7835 | Yes | ||
| 23 | ATP5D | 19949 | 2903 | 0.583 | 0.7446 | No | ||
| 24 | XDH | 22897 | 3454 | 0.313 | 0.7176 | No | ||
| 25 | ATP5E | 14321 | 3762 | 0.235 | 0.7030 | No | ||
| 26 | ATP5J | 880 22555 | 4543 | 0.127 | 0.6620 | No | ||
| 27 | AMPD2 | 1931 15197 | 5322 | 0.079 | 0.6208 | No | ||
| 28 | ATP5H | 12948 | 5552 | 0.070 | 0.6090 | No | ||
| 29 | ATP5F1 | 15212 | 6180 | 0.052 | 0.5757 | No | ||
| 30 | AMPD1 | 5051 | 6243 | 0.050 | 0.5728 | No | ||
| 31 | NP | 22027 9597 5273 5274 | 9774 | -0.004 | 0.3828 | No | ||
| 32 | ADK | 3302 3454 8555 | 11262 | -0.023 | 0.3030 | No | ||
| 33 | AK1 | 4363 | 12129 | -0.039 | 0.2567 | No | ||
| 34 | ATP5B | 19846 | 13631 | -0.088 | 0.1766 | No | ||
| 35 | AMPD3 | 4383 2110 | 13809 | -0.098 | 0.1678 | No | ||
| 36 | ATP5C1 | 8635 | 16131 | -0.780 | 0.0493 | No | ||
| 37 | DGUOK | 17099 1041 | 16691 | -1.355 | 0.0302 | No | ||
| 38 | NT5C2 | 3768 8052 | 17618 | -2.872 | 0.0038 | No | ||
| 39 | ADSSL1 | 21136 2087 | 18411 | -6.116 | 0.0110 | No |
