Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
Upregulated in class | transDMpreB |
GeneSet | REACTOME_DIABETES_PATHWAYS |
Enrichment Score (ES) | 0.6445997 |
Normalized Enrichment Score (NES) | 1.657875 |
Nominal p-value | 0.0 |
FDR q-value | 0.010365297 |
FWER p-Value | 0.186 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | RPL38 | 12562 20606 7475 | 0 | 11.156 | 0.0584 | Yes | ||
2 | ATP5G1 | 8636 | 101 | 7.285 | 0.0911 | Yes | ||
3 | UQCR | 12382 | 338 | 5.185 | 0.1054 | Yes | ||
4 | NDUFA10 | 7420 | 467 | 4.568 | 0.1224 | Yes | ||
5 | RPL14 | 19267 | 531 | 4.278 | 0.1413 | Yes | ||
6 | IDH3A | 19447 | 597 | 4.051 | 0.1590 | Yes | ||
7 | RPS2 | 9279 | 610 | 4.006 | 0.1793 | Yes | ||
8 | GNAS | 9025 2963 2752 | 614 | 3.993 | 0.2000 | Yes | ||
9 | MDH2 | 9399 | 644 | 3.915 | 0.2189 | Yes | ||
10 | NDUFS3 | 7553 12683 | 663 | 3.847 | 0.2381 | Yes | ||
11 | NDUFB3 | 12362 | 676 | 3.795 | 0.2573 | Yes | ||
12 | RPL4 | 7499 19411 | 678 | 3.790 | 0.2771 | Yes | ||
13 | RPS24 | 5399 | 693 | 3.723 | 0.2958 | Yes | ||
14 | UQCRB | 12545 | 697 | 3.715 | 0.3151 | Yes | ||
15 | CYCS | 8821 | 708 | 3.673 | 0.3337 | Yes | ||
16 | RPLP2 | 7401 | 757 | 3.552 | 0.3497 | Yes | ||
17 | ATP5A1 | 23505 | 815 | 3.395 | 0.3644 | Yes | ||
18 | EXOC8 | 4161 | 912 | 3.134 | 0.3756 | Yes | ||
19 | NDUFA9 | 12288 | 1004 | 2.896 | 0.3858 | Yes | ||
20 | NDUFS7 | 19946 | 1095 | 2.728 | 0.3952 | Yes | ||
21 | DDOST | 16021 | 1103 | 2.719 | 0.4090 | Yes | ||
22 | ATP5O | 22539 | 1145 | 2.647 | 0.4207 | Yes | ||
23 | ETFB | 18279 | 1151 | 2.632 | 0.4342 | Yes | ||
24 | RPS19 | 5398 | 1168 | 2.594 | 0.4469 | Yes | ||
25 | COX6C | 8775 | 1211 | 2.520 | 0.4578 | Yes | ||
26 | ATP5I | 8637 | 1283 | 2.411 | 0.4666 | Yes | ||
27 | RPL27A | 11181 6467 18130 | 1352 | 2.324 | 0.4750 | Yes | ||
28 | COX7C | 8776 | 1378 | 2.276 | 0.4856 | Yes | ||
29 | PKM2 | 3642 9573 | 1435 | 2.171 | 0.4939 | Yes | ||
30 | NDUFA8 | 14605 | 1479 | 2.088 | 0.5025 | Yes | ||
31 | COX7B | 7260 | 1495 | 2.062 | 0.5125 | Yes | ||
32 | NDUFV1 | 23953 | 1528 | 2.008 | 0.5212 | Yes | ||
33 | SDHD | 19125 | 1545 | 1.990 | 0.5308 | Yes | ||
34 | SLC30A7 | 15186 | 1551 | 1.977 | 0.5409 | Yes | ||
35 | NDUFC2 | 18183 | 1587 | 1.922 | 0.5490 | Yes | ||
36 | ATP5J2 | 12186 | 1596 | 1.907 | 0.5586 | Yes | ||
37 | NDUFS5 | 9296 | 1601 | 1.900 | 0.5683 | Yes | ||
38 | RPS15A | 6476 | 1605 | 1.897 | 0.5780 | Yes | ||
39 | RPL6 | 9747 | 1608 | 1.895 | 0.5878 | Yes | ||
40 | NDUFA7 | 12347 | 1666 | 1.819 | 0.5943 | Yes | ||
41 | SRP72 | 16819 | 1714 | 1.747 | 0.6009 | Yes | ||
42 | SEC61B | 12305 7266 | 1798 | 1.647 | 0.6050 | Yes | ||
43 | RPS23 | 12352 | 1891 | 1.549 | 0.6081 | Yes | ||
44 | IGFBP4 | 20670 9160 | 2058 | 1.326 | 0.6061 | Yes | ||
45 | SSR4 | 24303 5519 | 2066 | 1.318 | 0.6126 | Yes | ||
46 | IQGAP1 | 6619 | 2068 | 1.318 | 0.6194 | Yes | ||
47 | IDH3G | 24132 | 2081 | 1.305 | 0.6256 | Yes | ||
48 | ETFDH | 15313 | 2133 | 1.231 | 0.6293 | Yes | ||
49 | UQCRC2 | 18102 | 2212 | 1.145 | 0.6310 | Yes | ||
50 | COX6B1 | 4283 8479 | 2217 | 1.138 | 0.6368 | Yes | ||
51 | NDUFB5 | 12277 | 2232 | 1.123 | 0.6419 | Yes | ||
52 | NDUFB7 | 12429 | 2425 | 0.959 | 0.6365 | Yes | ||
53 | RPS3A | 9755 | 2442 | 0.946 | 0.6406 | Yes | ||
54 | NDUFA4 | 9451 | 2470 | 0.925 | 0.6440 | Yes | ||
55 | RPS4X | 9756 | 2543 | 0.869 | 0.6446 | Yes | ||
56 | COX6A1 | 8774 4553 | 2654 | 0.784 | 0.6427 | No | ||
57 | NDUFAB1 | 7667 | 2732 | 0.718 | 0.6423 | No | ||
58 | TPI1 | 5795 10212 | 2792 | 0.665 | 0.6426 | No | ||
59 | RPS17 | 9753 | 2876 | 0.607 | 0.6413 | No | ||
60 | ATP5D | 19949 | 2903 | 0.583 | 0.6429 | No | ||
61 | RPL8 | 22437 | 3000 | 0.522 | 0.6405 | No | ||
62 | RPS28 | 12009 | 3019 | 0.506 | 0.6421 | No | ||
63 | RPL39 | 12496 | 3113 | 0.455 | 0.6395 | No | ||
64 | RPL27 | 9740 | 3157 | 0.429 | 0.6394 | No | ||
65 | NDUFB10 | 23084 | 3260 | 0.386 | 0.6359 | No | ||
66 | RPL5 | 9746 | 3280 | 0.380 | 0.6368 | No | ||
67 | RPS29 | 9754 | 3343 | 0.356 | 0.6353 | No | ||
68 | RPL18A | 13358 | 3415 | 0.325 | 0.6332 | No | ||
69 | RPL41 | 12611 | 3429 | 0.321 | 0.6342 | No | ||
70 | RPS3 | 6549 11295 | 3446 | 0.314 | 0.6350 | No | ||
71 | ATP5E | 14321 | 3762 | 0.235 | 0.6191 | No | ||
72 | KLK3 | 16337 | 3881 | 0.214 | 0.6138 | No | ||
73 | PRKAR2B | 5288 2107 | 4138 | 0.172 | 0.6009 | No | ||
74 | SLC2A2 | 15623 1880 1855 | 4203 | 0.163 | 0.5983 | No | ||
75 | NDUFB8 | 7418 | 4250 | 0.158 | 0.5966 | No | ||
76 | EIF2S1 | 4658 | 4310 | 0.151 | 0.5942 | No | ||
77 | RPL28 | 5392 | 4322 | 0.150 | 0.5944 | No | ||
78 | RPS13 | 12633 | 4337 | 0.148 | 0.5944 | No | ||
79 | CTSL1 | 4574 | 4374 | 0.143 | 0.5932 | No | ||
80 | ATP5J | 880 22555 | 4543 | 0.127 | 0.5848 | No | ||
81 | VAMP2 | 20826 | 4730 | 0.114 | 0.5753 | No | ||
82 | NDUFA2 | 9450 | 4786 | 0.110 | 0.5729 | No | ||
83 | RPL37 | 12502 7421 22521 | 4913 | 0.101 | 0.5666 | No | ||
84 | PFKFB2 | 4116 5242 | 5075 | 0.092 | 0.5583 | No | ||
85 | RPS14 | 9751 | 5235 | 0.084 | 0.5502 | No | ||
86 | RPL18 | 450 5390 | 5252 | 0.083 | 0.5497 | No | ||
87 | RPSA | 19270 4984 | 5595 | 0.068 | 0.5316 | No | ||
88 | IGFALS | 9158 | 6071 | 0.054 | 0.5061 | No | ||
89 | ATP5F1 | 15212 | 6180 | 0.052 | 0.5005 | No | ||
90 | FFAR1 | 10583 | 6958 | 0.035 | 0.4586 | No | ||
91 | RAP1A | 8467 | 7142 | 0.032 | 0.4489 | No | ||
92 | EXOC5 | 8370 | 7175 | 0.032 | 0.4473 | No | ||
93 | RPS5 | 18391 | 8029 | 0.019 | 0.4012 | No | ||
94 | NDUFB4 | 22596 7541 | 8064 | 0.019 | 0.3994 | No | ||
95 | SDHB | 2348 12566 14880 | 8065 | 0.019 | 0.3995 | No | ||
96 | NDUFC1 | 7287 12339 | 8111 | 0.018 | 0.3972 | No | ||
97 | SRP19 | 2004 12341 | 8267 | 0.016 | 0.3889 | No | ||
98 | HSPA5 | 9045 | 8451 | 0.013 | 0.3790 | No | ||
99 | UQCRC1 | 10259 | 8509 | 0.013 | 0.3760 | No | ||
100 | PLA2G7 | 23233 | 8620 | 0.011 | 0.3701 | No | ||
101 | SYT5 | 17986 | 8742 | 0.009 | 0.3636 | No | ||
102 | IGF1 | 3352 9156 3409 | 8900 | 0.008 | 0.3551 | No | ||
103 | ABCC8 | 9941 11649 | 8933 | 0.007 | 0.3534 | No | ||
104 | MBTPS1 | 18730 3809 3770 | 9117 | 0.005 | 0.3436 | No | ||
105 | SDHA | 12436 | 9232 | 0.004 | 0.3374 | No | ||
106 | NKX2-2 | 5176 | 9246 | 0.003 | 0.3367 | No | ||
107 | IGFBP1 | 20948 | 9521 | -0.000 | 0.3219 | No | ||
108 | SSR2 | 15549 | 9804 | -0.004 | 0.3066 | No | ||
109 | RPL17 | 11429 6653 | 9805 | -0.004 | 0.3066 | No | ||
110 | PDX1 | 16621 | 10140 | -0.009 | 0.2886 | No | ||
111 | ADRA2A | 4355 | 10205 | -0.009 | 0.2852 | No | ||
112 | UQCRFS1 | 21499 | 10406 | -0.012 | 0.2744 | No | ||
113 | KIF5B | 4955 2031 | 10526 | -0.013 | 0.2680 | No | ||
114 | PGK1 | 9557 5244 | 10544 | -0.014 | 0.2672 | No | ||
115 | LEP | 17505 | 10909 | -0.019 | 0.2475 | No | ||
116 | GLP1R | 23304 | 11582 | -0.029 | 0.2113 | No | ||
117 | GCG | 14578 | 12019 | -0.036 | 0.1879 | No | ||
118 | IGFBP5 | 4899 | 12122 | -0.038 | 0.1825 | No | ||
119 | F2 | 14524 | 12383 | -0.044 | 0.1687 | No | ||
120 | CHRM3 | 21547 | 12669 | -0.052 | 0.1535 | No | ||
121 | KLF4 | 9230 4962 4963 | 12767 | -0.054 | 0.1485 | No | ||
122 | SRP54 | 6282 | 12830 | -0.056 | 0.1455 | No | ||
123 | KCNJ11 | 17822 | 12840 | -0.056 | 0.1453 | No | ||
124 | MMP2 | 18525 | 13525 | -0.081 | 0.1086 | No | ||
125 | ATP5B | 19846 | 13631 | -0.088 | 0.1034 | No | ||
126 | CS | 19839 | 13654 | -0.089 | 0.1027 | No | ||
127 | IGFBP6 | 9161 | 13878 | -0.103 | 0.0911 | No | ||
128 | PFKFB1 | 9552 | 14081 | -0.117 | 0.0808 | No | ||
129 | ERN1 | 8137 | 14176 | -0.124 | 0.0764 | No | ||
130 | RPS16 | 9752 | 14377 | -0.143 | 0.0663 | No | ||
131 | RPS21 | 12356 | 14413 | -0.147 | 0.0651 | No | ||
132 | RPLP1 | 3010 | 14694 | -0.183 | 0.0509 | No | ||
133 | PCSK2 | 9537 5231 14824 | 14862 | -0.208 | 0.0430 | No | ||
134 | CPE | 18868 | 14932 | -0.223 | 0.0404 | No | ||
135 | NDUFS2 | 4089 13760 | 15119 | -0.261 | 0.0317 | No | ||
136 | ATF4 | 22417 2239 | 15195 | -0.279 | 0.0291 | No | ||
137 | NFYA | 5172 | 15535 | -0.397 | 0.0128 | No | ||
138 | RPL37A | 9744 | 15688 | -0.457 | 0.0070 | No | ||
139 | RPS20 | 7438 | 15692 | -0.460 | 0.0092 | No | ||
140 | NDUFS4 | 9452 5157 3173 | 15820 | -0.525 | 0.0051 | No | ||
141 | RPL19 | 9736 | 15828 | -0.530 | 0.0075 | No | ||
142 | COX8A | 8777 | 16043 | -0.693 | -0.0005 | No | ||
143 | RPL11 | 12450 | 16091 | -0.736 | 0.0008 | No | ||
144 | RPS25 | 13270 | 16101 | -0.746 | 0.0042 | No | ||
145 | ATP5C1 | 8635 | 16131 | -0.780 | 0.0067 | No | ||
146 | OGDH | 9502 1412 | 16147 | -0.807 | 0.0101 | No | ||
147 | COX5B | 4552 | 16400 | -1.024 | 0.0018 | No | ||
148 | FAU | 8954 | 16489 | -1.116 | 0.0029 | No | ||
149 | NDUFS8 | 23950 | 16626 | -1.261 | 0.0021 | No | ||
150 | SEC11A | 12144 | 16735 | -1.418 | 0.0037 | No | ||
151 | SEC61G | 9795 | 16800 | -1.512 | 0.0081 | No | ||
152 | DLD | 2097 21090 | 16828 | -1.548 | 0.0148 | No | ||
153 | COX4I1 | 18444 | 16843 | -1.584 | 0.0223 | No | ||
154 | NDUFA6 | 12473 | 16866 | -1.614 | 0.0296 | No | ||
155 | NDUFA11 | 12832 | 17128 | -1.999 | 0.0259 | No | ||
156 | SRP14 | 9894 | 17365 | -2.419 | 0.0257 | No | ||
157 | PDHA1 | 24020 | 17378 | -2.429 | 0.0378 | No | ||
158 | PRKCA | 20174 | 17460 | -2.570 | 0.0469 | No | ||
159 | SUCLG1 | 17409 1059 | 17675 | -3.004 | 0.0510 | No |