Details for gene set PROTEIN_KINASE

Table: GSEA Results Summary

Dataset	Set_04_transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB_repos
Phenotype	phenotype_transDMpreB_versus_DMpreB.cls#transDMpreB_versus_DMpreB_repos
Upregulated in class	transDMpreB
GeneSet	PROTEIN_KINASE_ACTIVITY
Enrichment Score (ES)	0.49525878
Normalized Enrichment Score (NES)	1.5072201
Nominal p-value	0.0
FDR q-value	0.93522555
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PRKCB1	1693 9574	2	3.865	0.0368	Yes
2	LIMK2	9278 1296	47	2.806	0.0612	Yes
3	BRD2	4735 8984 7628	51	2.773	0.0875	Yes
4	MAP4K2	6457	72	2.603	0.1113	Yes
5	MARK2	8899	74	2.595	0.1360	Yes
6	STK11	19950	114	2.391	0.1567	Yes
7	CSNK1G2	19940 3418	246	2.062	0.1693	Yes
8	MAP3K11	11163	275	2.001	0.1869	Yes
9	IRAK1	4916	322	1.872	0.2022	Yes
10	MAPK14	23313	334	1.857	0.2194	Yes
11	CIT	16727	367	1.809	0.2349	Yes
12	ROCK1	5386	409	1.746	0.2493	Yes
13	TRIM27	3264 9720	491	1.636	0.2606	Yes
14	TYK2	12058 19215	563	1.543	0.2714	Yes
15	EIF2AK2	22892	621	1.457	0.2822	Yes
16	RPS6KA1	15725	736	1.314	0.2886	Yes
17	MAP2K1	19082	767	1.285	0.2992	Yes
18	MAP3K3	20626	808	1.254	0.3090	Yes
19	MKNK2	3299 9392	809	1.250	0.3210	Yes
20	STK4	14743	965	1.084	0.3229	Yes
21	MAP3K7	16255	1018	1.035	0.3299	Yes
22	MAP3K7IP1	2193 2171 22419	1041	1.019	0.3385	Yes
23	WNK1	1109 17020 6106	1071	1.007	0.3465	Yes
24	DYRK1A	4649	1113	0.993	0.3537	Yes
25	CHEK2	16751 3587	1190	0.938	0.3586	Yes
26	TLK2	20628	1238	0.905	0.3646	Yes
27	MKNK1	2504	1254	0.891	0.3723	Yes
28	TLK1	14563	1260	0.887	0.3805	Yes
29	MAP3K8	23495	1281	0.872	0.3878	Yes
30	CHUK	23665	1310	0.853	0.3944	Yes
31	SRPK1	23049	1373	0.817	0.3988	Yes
32	TNK2	22784	1375	0.816	0.4066	Yes
33	LTK	14467	1380	0.814	0.4141	Yes
34	PRKACB	15140	1381	0.813	0.4219	Yes
35	EIF2AK3	17421	1388	0.809	0.4293	Yes
36	TEC	16514	1394	0.805	0.4367	Yes
37	CDK5	16591	1415	0.791	0.4432	Yes
38	NLK	5179 5178	1529	0.723	0.4439	Yes
39	SNF1LK	23033	1570	0.699	0.4484	Yes
40	ULK1	16436	1603	0.681	0.4532	Yes
41	PDPK1	23097	1610	0.675	0.4593	Yes
42	PIM1	23308	1691	0.635	0.4610	Yes
43	MAP2K3	20856	1692	0.634	0.4670	Yes
44	STK16	14216	1753	0.596	0.4695	Yes
45	PHKG2	18065	1764	0.591	0.4746	Yes
46	TWF1	5321	1781	0.572	0.4792	Yes
47	IRAK3	19617	1842	0.541	0.4811	Yes
48	CDK2	3438 3373 19592 3322	1865	0.529	0.4849	Yes
49	PRKCZ	5260	1877	0.520	0.4893	Yes
50	PLK3	15790	1938	0.487	0.4907	Yes
51	PTK2B	21776	2197	0.385	0.4803	Yes
52	MAP4K3	22887	2224	0.377	0.4825	Yes
53	MAP3K2	11165	2345	0.340	0.4792	Yes
54	IRAK2	17324	2364	0.332	0.4814	Yes
55	EXOSC10	2482 11943	2402	0.322	0.4824	Yes
56	PHKA1	2645 24089 2582	2405	0.321	0.4854	Yes
57	MARK4	10572	2427	0.313	0.4872	Yes
58	ACVR2B	19276	2436	0.310	0.4898	Yes
59	ALS2CR2	5966 969	2443	0.307	0.4924	Yes
60	CLK2	1883 15544	2477	0.298	0.4934	Yes
61	ROCK2	21309 5387	2496	0.295	0.4953	Yes
62	AXL	17922	2667	0.256	0.4884	No
63	IGF2R	23123	2682	0.253	0.4901	No
64	MAPK12	2182 2215 22164	2721	0.246	0.4904	No
65	MAP3K12	6454 11164	2832	0.229	0.4866	No
66	SNF1LK2	6168 10649	2838	0.228	0.4885	No
67	STK10	5532 9916	2897	0.217	0.4874	No
68	PDGFRB	23539	2909	0.214	0.4888	No
69	MAP3K5	20079 11166	3069	0.191	0.4820	No
70	RIPK1	5381	3213	0.170	0.4758	No
71	CSNK1E	6570 2211 11332	3242	0.166	0.4759	No
72	MAP4K4	11241	3363	0.151	0.4708	No
73	MAP3K10	3831 17916	3402	0.147	0.4701	No
74	PHKA2	8471 24216	3539	0.135	0.4640	No
75	PAK1	9527	3601	0.130	0.4620	No
76	ERN2	17651	3631	0.128	0.4616	No
77	PLK1	9590 5266	3640	0.127	0.4624	No
78	RIPK2	2528 15935	3734	0.119	0.4585	No
79	VRK1	5862 2049	3991	0.103	0.4455	No
80	EIF2AK4	14909	4029	0.100	0.4444	No
81	TXK	16513	4030	0.100	0.4454	No
82	CCL4	1362 20730	4072	0.097	0.4441	No
83	MAPK9	1233 20903 1383	4094	0.096	0.4439	No
84	KIT	16823	4135	0.093	0.4426	No
85	MST1R	19318 3106	4189	0.090	0.4405	No
86	MAP3K9	6872	4297	0.084	0.4355	No
87	MAPK13	23314	4397	0.080	0.4309	No
88	BCR	8478 3384 19990	4523	0.075	0.4248	No
89	STK17B	13957	4545	0.074	0.4244	No
90	CSNK1D	4181 8352 1387	4572	0.073	0.4237	No
91	CCL2	9788	4747	0.067	0.4148	No
92	LIMK1	16350	4789	0.065	0.4132	No
93	RPS6KA5	2076 21005	4837	0.064	0.4113	No
94	MINK1	20802	4840	0.064	0.4118	No
95	PRKAG3	6295	4882	0.063	0.4101	No
96	TTK	19366	5063	0.057	0.4009	No
97	RPS6KA2	9759 9758	5200	0.053	0.3940	No
98	MAPK7	1381 20414	5307	0.050	0.3887	No
99	ERBB3	19593	5331	0.050	0.3879	No
100	ACVR1C	14585	5425	0.048	0.3833	No
101	FGFR1	3789 8968	5469	0.047	0.3814	No
102	EPHB2	4675 2440 8910	5497	0.046	0.3804	No
103	CDC42BPA	10384	5645	0.043	0.3728	No
104	ALK	8574	5658	0.042	0.3725	No
105	NEK4	22061 3687 5534	5659	0.042	0.3729	No
106	TSSK3	4388	5706	0.042	0.3708	No
107	PDK4	17222	5753	0.041	0.3687	No
108	CDK3	20588	5843	0.039	0.3642	No
109	NEK2	5160	5898	0.038	0.3617	No
110	MAP4K1	18313	6010	0.036	0.3560	No
111	RYK	19338 3870	6139	0.034	0.3493	No
112	MAPK11	2264 9618 22163	6170	0.033	0.3480	No
113	MAP3K6	16054	6199	0.033	0.3468	No
114	MAPKAPK5	16387	6436	0.029	0.3342	No
115	CSNK2B	23008	7009	0.020	0.3033	No
116	SGK3	5025 4053 9312 3997 4025	7322	0.016	0.2864	No
117	ACVRL1	22354	7450	0.014	0.2796	No
118	FRK	20056	7633	0.012	0.2698	No
119	EPHA5	16498	7721	0.011	0.2652	No
120	MUSK	5199	7752	0.010	0.2637	No
121	MAP3K4	23126	7801	0.010	0.2612	No
122	ITK	4934	8021	0.007	0.2493	No
123	ACVR2A	8542	8040	0.007	0.2484	No
124	LYN	16281	8372	0.004	0.2304	No
125	PDGFRL	7584 18627	8619	0.000	0.2170	No
126	RIPK4	22526	8667	0.000	0.2145	No
127	ATM	2976 19115	8700	-0.000	0.2127	No
128	NRP2	5194 9486 5195	8763	-0.001	0.2094	No
129	MYLK	22778 4213	8871	-0.002	0.2036	No
130	SNRK	5467 5468 9840	9022	-0.004	0.1954	No
131	EPGN	16798	9113	-0.005	0.1906	No
132	PRKCE	9575	9170	-0.006	0.1876	No
133	ROR2	21462	9226	-0.007	0.1846	No
134	CDK7	21365	9267	-0.007	0.1825	No
135	STK38	23045	9365	-0.009	0.1773	No
136	RPS6KB2	7198	9416	-0.009	0.1747	No
137	HUNK	22708	9526	-0.011	0.1689	No
138	PRKCI	9576	9605	-0.012	0.1647	No
139	AKT1	8568	9662	-0.013	0.1618	No
140	EFNB3	20391	9854	-0.015	0.1516	No
141	TESK2	10504	9879	-0.015	0.1504	No
142	TTN	14552 2743 14553	9974	-0.016	0.1454	No
143	PRKX	9619 5290	10149	-0.019	0.1361	No
144	DAPK2	19395	10195	-0.019	0.1339	No
145	PTK6	14308	10273	-0.020	0.1299	No
146	NEK11	3099 19016	10302	-0.021	0.1286	No
147	DDR1	1625 23000	10513	-0.024	0.1173	No
148	MAP4K5	11853 21048 2101 2142	10536	-0.024	0.1164	No
149	TGFA	17381	10539	-0.024	0.1165	No
150	CSNK2A1	14797	10544	-0.024	0.1165	No
151	TGFBR1	16213 10165 5745	10621	-0.025	0.1126	No
152	PRKCH	21246	10685	-0.026	0.1094	No
153	FLT4	20904 1461	10833	-0.028	0.1017	No
154	TSSK1A	5802	10898	-0.029	0.0985	No
155	PDGFRA	16824	10927	-0.030	0.0973	No
156	TIE1	15779	11035	-0.031	0.0917	No
157	DDR2	13767	11111	-0.033	0.0880	No
158	SGK2	14750	11144	-0.033	0.0865	No
159	CSNK1A1	8204	11168	-0.034	0.0856	No
160	AKT2	4365 4366	11247	-0.035	0.0817	No
161	TRIB1	22467	11393	-0.037	0.0742	No
162	MAP2K7	6453	11507	-0.039	0.0684	No
163	MAPK4	23409	11523	-0.039	0.0679	No
164	KDR	16509	11588	-0.041	0.0648	No
165	PLK4	1870 1874	11649	-0.042	0.0620	No
166	TEK	16175	11723	-0.043	0.0584	No
167	TSSK6	18594	11786	-0.045	0.0555	No
168	ILK	9177 1618	11833	-0.046	0.0534	No
169	TYRO3	5811	11890	-0.047	0.0508	No
170	ROR1	6472	11897	-0.047	0.0509	No
171	TAOK2	10610 3794	12072	-0.051	0.0419	No
172	RPS6KC1	6729	12158	-0.053	0.0378	No
173	EGFR	1329 20944	12205	-0.054	0.0358	No
174	STK38L	17240	12247	-0.055	0.0341	No
175	PRKD1	2074 21075	12420	-0.059	0.0253	No
176	IGF1R	9157	12594	-0.064	0.0165	No
177	CSF1R	8800 23540	12644	-0.066	0.0145	No
178	FLT1	3483 16287	12672	-0.067	0.0136	No
179	FLT3	16288	12713	-0.068	0.0121	No
180	PTK7	22959	12859	-0.073	0.0049	No
181	MAPKAPK2	13838	12872	-0.073	0.0049	No
182	CPNE3	7689	12878	-0.073	0.0054	No
183	ERBB4	13933 4678	12894	-0.074	0.0053	No
184	MERTK	5094	12998	-0.078	0.0004	No
185	NEK6	15018	13233	-0.087	-0.0115	No
186	MAPK10	11169	13511	-0.099	-0.0256	No
187	DAPK3	19932	13525	-0.100	-0.0254	No
188	MAP3K13	22814	13677	-0.108	-0.0326	No
189	TSSK2	10225	13695	-0.109	-0.0325	No
190	EFNA3	15278	13781	-0.114	-0.0360	No
191	CDKL1	12914	13816	-0.116	-0.0368	No
192	EPHB6	17473	13860	-0.119	-0.0380	No
193	HIPK3	14504	14019	-0.129	-0.0453	No
194	INSR	18950	14023	-0.129	-0.0443	No
195	NTRK1	15299	14024	-0.129	-0.0430	No
196	MARK1	5955	14063	-0.131	-0.0438	No
197	MET	17520	14073	-0.132	-0.0431	No
198	GTF2H1	4069 18236	14080	-0.132	-0.0421	No
199	LATS2	11923 6928	14097	-0.134	-0.0417	No
200	CLK1	13951 4127 4529 8748	14160	-0.138	-0.0438	No
201	IKBKE	67	14176	-0.139	-0.0433	No
202	CDK9	14619	14177	-0.139	-0.0420	No
203	ERBB2	8913	14207	-0.142	-0.0422	No
204	CAMKK2	9870	14257	-0.146	-0.0434	No
205	TGFBR2	2994 3001 10167	14270	-0.147	-0.0427	No
206	FGFR4	3226	14308	-0.151	-0.0433	No
207	WNK3	24227	14319	-0.151	-0.0424	No
208	MAST1	12143	14378	-0.157	-0.0440	No
209	TRIB2	21102	14484	-0.168	-0.0481	No
210	MAP2K6	20614 1414	14512	-0.170	-0.0480	No
211	TESK1	16233	14514	-0.171	-0.0464	No
212	CDK5R1	20745	14516	-0.171	-0.0448	No
213	PDK2	20285	14532	-0.172	-0.0440	No
214	ACVR1B	4335 22353	14601	-0.180	-0.0460	No
215	PINK1	12752 15703	14650	-0.185	-0.0468	No
216	ERN1	8137	14698	-0.190	-0.0476	No
217	GSK3B	22761	14988	-0.227	-0.0611	No
218	WNK4	7644	15127	-0.244	-0.0663	No
219	BRDT	4327	15292	-0.272	-0.0726	No
220	CDK10	3818 6157 10635 3894	15345	-0.281	-0.0728	No
221	CSNK2A2	4567 8808	15415	-0.291	-0.0738	No
222	LMTK2	16631	15467	-0.303	-0.0737	No
223	SRPK2	5513	15688	-0.354	-0.0823	No
224	BRSK2	190	15781	-0.373	-0.0837	No
225	RPS6KA3	8490	15832	-0.385	-0.0828	No
226	PIM2	5249 9564 9565	15952	-0.417	-0.0853	No
227	CRIM1	403	16007	-0.433	-0.0841	No
228	UHMK1	4038 4957	16132	-0.467	-0.0863	No
229	EFNA4	1866 15277	16157	-0.474	-0.0831	No
230	EIF2AK1	4869	16300	-0.517	-0.0859	No
231	PXK	26	16395	-0.551	-0.0858	No
232	PDK3	24111	16524	-0.598	-0.0870	No
233	MAPKAPK3	19003	16613	-0.637	-0.0857	No
234	MAPK8	6459	16644	-0.646	-0.0812	No
235	COL4A3BP	3221 7522	16725	-0.687	-0.0790	No
236	PDK1	14987	16809	-0.726	-0.0766	No
237	CDC42BPB	20982	16817	-0.728	-0.0700	No
238	PAK2	10310 5875	16924	-0.783	-0.0683	No
239	ACVR1	4334	17118	-0.886	-0.0703	No
240	CRKL	4560	17208	-0.926	-0.0663	No
241	MAPK1	1642 11167	17667	-1.160	-0.0802	No
242	VRK2	947 20511	17714	-1.192	-0.0713	No
243	BCKDK	18061 1391	17800	-1.254	-0.0640	No
244	PBK	11959	17983	-1.395	-0.0606	No
245	MAPK6	19062	18044	-1.445	-0.0500	No
246	PRKAG1	22135	18092	-1.496	-0.0383	No
247	STK19	23016 1569 1508	18130	-1.543	-0.0256	No
248	PRKD3	13252 7956	18136	-1.550	-0.0111	No
249	STK3	7084	18277	-1.738	-0.0021	No
250	RIPK3	21817	18461	-2.145	0.0084	No