Dataset | Set_04_transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB_repos |
Phenotype | phenotype_transDMpreB_versus_DMpreB.cls#transDMpreB_versus_DMpreB_repos |
Upregulated in class | transDMpreB |
GeneSet | PROTEIN_AMINO_ACID_PHOSPHORYLATION |
Enrichment Score (ES) | 0.4894728 |
Normalized Enrichment Score (NES) | 1.4793981 |
Nominal p-value | 0.0 |
FDR q-value | 0.7276981 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PRKCB1 | 1693 9574 | 2 | 3.865 | 0.0329 | Yes | ||
2 | CDC2L2 | 15964 2419 | 45 | 2.809 | 0.0545 | Yes | ||
3 | MAP4K2 | 6457 | 72 | 2.603 | 0.0753 | Yes | ||
4 | MARK2 | 8899 | 74 | 2.595 | 0.0974 | Yes | ||
5 | MAST2 | 9423 | 112 | 2.400 | 0.1158 | Yes | ||
6 | STK11 | 19950 | 114 | 2.391 | 0.1362 | Yes | ||
7 | BTK | 24061 | 118 | 2.378 | 0.1563 | Yes | ||
8 | PCTK1 | 24369 | 122 | 2.344 | 0.1761 | Yes | ||
9 | CSNK1G2 | 19940 3418 | 246 | 2.062 | 0.1870 | Yes | ||
10 | MAP3K11 | 11163 | 275 | 2.001 | 0.2026 | Yes | ||
11 | ROCK1 | 5386 | 409 | 1.746 | 0.2102 | Yes | ||
12 | PKN1 | 11567 6799 | 508 | 1.624 | 0.2187 | Yes | ||
13 | TYK2 | 12058 19215 | 563 | 1.543 | 0.2289 | Yes | ||
14 | GSG2 | 20356 | 592 | 1.502 | 0.2402 | Yes | ||
15 | ABI3 | 7314 | 691 | 1.380 | 0.2467 | Yes | ||
16 | CCND1 | 4487 4488 8707 17535 | 698 | 1.368 | 0.2580 | Yes | ||
17 | PRKCD | 21897 | 716 | 1.338 | 0.2685 | Yes | ||
18 | MAP3K3 | 20626 | 808 | 1.254 | 0.2742 | Yes | ||
19 | MKNK2 | 3299 9392 | 809 | 1.250 | 0.2849 | Yes | ||
20 | CCND3 | 4489 4490 | 849 | 1.205 | 0.2931 | Yes | ||
21 | RPS6KA4 | 23804 | 933 | 1.130 | 0.2982 | Yes | ||
22 | CSK | 8805 | 940 | 1.117 | 0.3074 | Yes | ||
23 | MAPK3 | 6458 11170 | 961 | 1.090 | 0.3156 | Yes | ||
24 | STK4 | 14743 | 965 | 1.084 | 0.3247 | Yes | ||
25 | CCNT1 | 22140 11607 | 1002 | 1.050 | 0.3317 | Yes | ||
26 | PICK1 | 9560 22424 | 1012 | 1.037 | 0.3400 | Yes | ||
27 | WNK1 | 1109 17020 6106 | 1071 | 1.007 | 0.3455 | Yes | ||
28 | DYRK1A | 4649 | 1113 | 0.993 | 0.3517 | Yes | ||
29 | GMFG | 1590 18319 | 1127 | 0.986 | 0.3594 | Yes | ||
30 | PKN2 | 1909 4271 | 1131 | 0.984 | 0.3676 | Yes | ||
31 | RAF1 | 17035 | 1186 | 0.942 | 0.3727 | Yes | ||
32 | TLK2 | 20628 | 1238 | 0.905 | 0.3777 | Yes | ||
33 | MKNK1 | 2504 | 1254 | 0.891 | 0.3844 | Yes | ||
34 | TLK1 | 14563 | 1260 | 0.887 | 0.3917 | Yes | ||
35 | MAP3K8 | 23495 | 1281 | 0.872 | 0.3981 | Yes | ||
36 | JAK3 | 9198 4936 | 1299 | 0.858 | 0.4045 | Yes | ||
37 | CHUK | 23665 | 1310 | 0.853 | 0.4112 | Yes | ||
38 | SRPK1 | 23049 | 1373 | 0.817 | 0.4148 | Yes | ||
39 | TNK2 | 22784 | 1375 | 0.816 | 0.4217 | Yes | ||
40 | LTK | 14467 | 1380 | 0.814 | 0.4284 | Yes | ||
41 | PRKACB | 15140 | 1381 | 0.813 | 0.4354 | Yes | ||
42 | EIF2AK3 | 17421 | 1388 | 0.809 | 0.4419 | Yes | ||
43 | TEC | 16514 | 1394 | 0.805 | 0.4485 | Yes | ||
44 | IL12A | 4913 | 1462 | 0.763 | 0.4514 | Yes | ||
45 | SRP72 | 16819 | 1479 | 0.753 | 0.4569 | Yes | ||
46 | SNF1LK | 23033 | 1570 | 0.699 | 0.4580 | Yes | ||
47 | ULK1 | 16436 | 1603 | 0.681 | 0.4621 | Yes | ||
48 | PDPK1 | 23097 | 1610 | 0.675 | 0.4675 | Yes | ||
49 | PIM1 | 23308 | 1691 | 0.635 | 0.4686 | Yes | ||
50 | STK16 | 14216 | 1753 | 0.596 | 0.4703 | Yes | ||
51 | TWF1 | 5321 | 1781 | 0.572 | 0.4737 | Yes | ||
52 | IRAK3 | 19617 | 1842 | 0.541 | 0.4751 | Yes | ||
53 | CRKRS | 7608 12779 | 1851 | 0.537 | 0.4792 | Yes | ||
54 | PRKCZ | 5260 | 1877 | 0.520 | 0.4823 | Yes | ||
55 | ITGB2 | 19978 | 1901 | 0.507 | 0.4854 | Yes | ||
56 | PLK3 | 15790 | 1938 | 0.487 | 0.4876 | Yes | ||
57 | CCND2 | 16987 | 2088 | 0.425 | 0.4831 | Yes | ||
58 | TNKS | 5786 | 2193 | 0.385 | 0.4807 | Yes | ||
59 | PTK2B | 21776 | 2197 | 0.385 | 0.4838 | Yes | ||
60 | MAP4K3 | 22887 | 2224 | 0.377 | 0.4856 | Yes | ||
61 | HCLS1 | 22770 | 2314 | 0.350 | 0.4838 | Yes | ||
62 | MAP3K2 | 11165 | 2345 | 0.340 | 0.4850 | Yes | ||
63 | IRAK2 | 17324 | 2364 | 0.332 | 0.4869 | Yes | ||
64 | MARK4 | 10572 | 2427 | 0.313 | 0.4862 | Yes | ||
65 | ALS2CR2 | 5966 969 | 2443 | 0.307 | 0.4880 | Yes | ||
66 | ROCK2 | 21309 5387 | 2496 | 0.295 | 0.4877 | Yes | ||
67 | CAMK2A | 2024 23541 1980 | 2511 | 0.290 | 0.4894 | Yes | ||
68 | ABL1 | 2693 4301 2794 | 2554 | 0.279 | 0.4895 | Yes | ||
69 | RAGE | 6465 2056 2165 | 2624 | 0.265 | 0.4880 | No | ||
70 | MAPK12 | 2182 2215 22164 | 2721 | 0.246 | 0.4849 | No | ||
71 | CDK2AP1 | 8858 | 2787 | 0.234 | 0.4833 | No | ||
72 | MAP3K12 | 6454 11164 | 2832 | 0.229 | 0.4829 | No | ||
73 | SNF1LK2 | 6168 10649 | 2838 | 0.228 | 0.4845 | No | ||
74 | STK10 | 5532 9916 | 2897 | 0.217 | 0.4832 | No | ||
75 | AURKC | 5533 | 3113 | 0.185 | 0.4731 | No | ||
76 | CSNK1E | 6570 2211 11332 | 3242 | 0.166 | 0.4676 | No | ||
77 | FYB | 10717 | 3283 | 0.162 | 0.4668 | No | ||
78 | CLCF1 | 12160 3742 | 3354 | 0.152 | 0.4643 | No | ||
79 | MAP4K4 | 11241 | 3363 | 0.151 | 0.4651 | No | ||
80 | MAP3K10 | 3831 17916 | 3402 | 0.147 | 0.4643 | No | ||
81 | PAK1 | 9527 | 3601 | 0.130 | 0.4546 | No | ||
82 | JAK2 | 23893 9197 3706 | 3607 | 0.130 | 0.4555 | No | ||
83 | ERN2 | 17651 | 3631 | 0.128 | 0.4553 | No | ||
84 | MATK | 3425 19930 | 3883 | 0.109 | 0.4426 | No | ||
85 | NF2 | 1222 5166 | 3945 | 0.105 | 0.4402 | No | ||
86 | TGFB1 | 18332 | 3946 | 0.105 | 0.4411 | No | ||
87 | VRK1 | 5862 2049 | 3991 | 0.103 | 0.4395 | No | ||
88 | PKN3 | 15057 | 4001 | 0.102 | 0.4399 | No | ||
89 | EIF2AK4 | 14909 | 4029 | 0.100 | 0.4393 | No | ||
90 | TXK | 16513 | 4030 | 0.100 | 0.4402 | No | ||
91 | IL3 | 20453 | 4209 | 0.089 | 0.4312 | No | ||
92 | CAMK4 | 4473 | 4269 | 0.086 | 0.4287 | No | ||
93 | MAP3K9 | 6872 | 4297 | 0.084 | 0.4280 | No | ||
94 | FGR | 4723 | 4299 | 0.084 | 0.4287 | No | ||
95 | IL31RA | 21347 | 4518 | 0.075 | 0.4174 | No | ||
96 | BCR | 8478 3384 19990 | 4523 | 0.075 | 0.4179 | No | ||
97 | STK17B | 13957 | 4545 | 0.074 | 0.4173 | No | ||
98 | CSNK1D | 4181 8352 1387 | 4572 | 0.073 | 0.4166 | No | ||
99 | ABL2 | 8509 | 4681 | 0.069 | 0.4113 | No | ||
100 | CCL2 | 9788 | 4747 | 0.067 | 0.4083 | No | ||
101 | LIMK1 | 16350 | 4789 | 0.065 | 0.4066 | No | ||
102 | BMX | 2566 2585 24010 | 4817 | 0.064 | 0.4057 | No | ||
103 | MYOD1 | 18237 | 4820 | 0.064 | 0.4061 | No | ||
104 | RPS6KA5 | 2076 21005 | 4837 | 0.064 | 0.4058 | No | ||
105 | MINK1 | 20802 | 4840 | 0.064 | 0.4063 | No | ||
106 | HCK | 14787 | 4919 | 0.061 | 0.4025 | No | ||
107 | PCTK2 | 19907 | 5225 | 0.053 | 0.3864 | No | ||
108 | CDKL5 | 24019 | 5330 | 0.050 | 0.3812 | No | ||
109 | ERBB3 | 19593 | 5331 | 0.050 | 0.3816 | No | ||
110 | CTBP1 | 16566 | 5414 | 0.048 | 0.3775 | No | ||
111 | RET | 17028 | 5433 | 0.047 | 0.3769 | No | ||
112 | EPHB2 | 4675 2440 8910 | 5497 | 0.046 | 0.3739 | No | ||
113 | BMPR1A | 8660 4450 | 5558 | 0.045 | 0.3710 | No | ||
114 | CDC42BPA | 10384 | 5645 | 0.043 | 0.3667 | No | ||
115 | NEK4 | 22061 3687 5534 | 5659 | 0.042 | 0.3664 | No | ||
116 | TSSK3 | 4388 | 5706 | 0.042 | 0.3642 | No | ||
117 | PRKG1 | 5289 | 5722 | 0.041 | 0.3638 | No | ||
118 | GRK1 | 18677 | 5878 | 0.038 | 0.3556 | No | ||
119 | IL5 | 20884 10220 | 5994 | 0.036 | 0.3497 | No | ||
120 | MAP4K1 | 18313 | 6010 | 0.036 | 0.3492 | No | ||
121 | CARD14 | 20574 1424 | 6133 | 0.034 | 0.3428 | No | ||
122 | MAP3K6 | 16054 | 6199 | 0.033 | 0.3396 | No | ||
123 | ERC1 | 1013 17021 995 1136 | 6527 | 0.027 | 0.3220 | No | ||
124 | TNK1 | 13516 | 6699 | 0.024 | 0.3129 | No | ||
125 | CCL11 | 20742 | 6717 | 0.024 | 0.3122 | No | ||
126 | CBLC | 17938 | 7212 | 0.017 | 0.2855 | No | ||
127 | SGK3 | 5025 4053 9312 3997 4025 | 7322 | 0.016 | 0.2797 | No | ||
128 | ACVRL1 | 22354 | 7450 | 0.014 | 0.2729 | No | ||
129 | FRK | 20056 | 7633 | 0.012 | 0.2631 | No | ||
130 | EPHA5 | 16498 | 7721 | 0.011 | 0.2584 | No | ||
131 | LYN | 16281 | 8372 | 0.004 | 0.2231 | No | ||
132 | DAPK1 | 7632 | 8443 | 0.003 | 0.2193 | No | ||
133 | RIPK4 | 22526 | 8667 | 0.000 | 0.2072 | No | ||
134 | EPHA8 | 15705 | 8807 | -0.002 | 0.1996 | No | ||
135 | MYLK | 22778 4213 | 8871 | -0.002 | 0.1962 | No | ||
136 | SNRK | 5467 5468 9840 | 9022 | -0.004 | 0.1881 | No | ||
137 | PRKCE | 9575 | 9170 | -0.006 | 0.1801 | No | ||
138 | STK38 | 23045 | 9365 | -0.009 | 0.1697 | No | ||
139 | IL20 | 13840 | 9485 | -0.010 | 0.1633 | No | ||
140 | MYO3A | 10065 | 9546 | -0.011 | 0.1601 | No | ||
141 | ADAM10 | 4336 | 9583 | -0.011 | 0.1582 | No | ||
142 | PRKCI | 9576 | 9605 | -0.012 | 0.1572 | No | ||
143 | CAMK1 | 1037 1170 17044 | 9642 | -0.012 | 0.1553 | No | ||
144 | AKT1 | 8568 | 9662 | -0.013 | 0.1544 | No | ||
145 | ABI2 | 4037 6830 | 9877 | -0.015 | 0.1429 | No | ||
146 | TESK2 | 10504 | 9879 | -0.015 | 0.1430 | No | ||
147 | BMPR1B | 8661 15152 4451 | 9935 | -0.016 | 0.1401 | No | ||
148 | TTN | 14552 2743 14553 | 9974 | -0.016 | 0.1382 | No | ||
149 | PRKX | 9619 5290 | 10149 | -0.019 | 0.1289 | No | ||
150 | BMP4 | 21863 | 10151 | -0.019 | 0.1290 | No | ||
151 | DAPK2 | 19395 | 10195 | -0.019 | 0.1268 | No | ||
152 | PTK6 | 14308 | 10273 | -0.020 | 0.1228 | No | ||
153 | NEK11 | 3099 19016 | 10302 | -0.021 | 0.1214 | No | ||
154 | ERG | 1686 8915 | 10402 | -0.022 | 0.1162 | No | ||
155 | MAP4K5 | 11853 21048 2101 2142 | 10536 | -0.024 | 0.1092 | No | ||
156 | CSNK2A1 | 14797 | 10544 | -0.024 | 0.1090 | No | ||
157 | TGFBR1 | 16213 10165 5745 | 10621 | -0.025 | 0.1051 | No | ||
158 | PRKCH | 21246 | 10685 | -0.026 | 0.1019 | No | ||
159 | TSSK1A | 5802 | 10898 | -0.029 | 0.0906 | No | ||
160 | CSNK1A1 | 8204 | 11168 | -0.034 | 0.0763 | No | ||
161 | TRIB1 | 22467 | 11393 | -0.037 | 0.0644 | No | ||
162 | IGFBP3 | 4898 | 11433 | -0.038 | 0.0626 | No | ||
163 | MAPK4 | 23409 | 11523 | -0.039 | 0.0581 | No | ||
164 | PRPF4B | 3208 5295 | 11612 | -0.041 | 0.0537 | No | ||
165 | PLK4 | 1870 1874 | 11649 | -0.042 | 0.0521 | No | ||
166 | TSSK6 | 18594 | 11786 | -0.045 | 0.0450 | No | ||
167 | ILK | 9177 1618 | 11833 | -0.046 | 0.0429 | No | ||
168 | EGFR | 1329 20944 | 12205 | -0.054 | 0.0232 | No | ||
169 | STK38L | 17240 | 12247 | -0.055 | 0.0214 | No | ||
170 | TDGF1 | 5704 10108 | 12350 | -0.057 | 0.0164 | No | ||
171 | PRKD1 | 2074 21075 | 12420 | -0.059 | 0.0131 | No | ||
172 | IGF1R | 9157 | 12594 | -0.064 | 0.0043 | No | ||
173 | LIPE | 17927 | 12721 | -0.068 | -0.0020 | No | ||
174 | FES | 17779 3949 | 12837 | -0.072 | -0.0077 | No | ||
175 | MAPKAPK2 | 13838 | 12872 | -0.073 | -0.0089 | No | ||
176 | MERTK | 5094 | 12998 | -0.078 | -0.0150 | No | ||
177 | NEK6 | 15018 | 13233 | -0.087 | -0.0270 | No | ||
178 | IL22RA2 | 20082 | 13492 | -0.099 | -0.0402 | No | ||
179 | DAPK3 | 19932 | 13525 | -0.100 | -0.0411 | No | ||
180 | MAP3K13 | 22814 | 13677 | -0.108 | -0.0484 | No | ||
181 | TSSK2 | 10225 | 13695 | -0.109 | -0.0484 | No | ||
182 | CDKL1 | 12914 | 13816 | -0.116 | -0.0539 | No | ||
183 | HIPK3 | 14504 | 14019 | -0.129 | -0.0638 | No | ||
184 | INSR | 18950 | 14023 | -0.129 | -0.0629 | No | ||
185 | MARK1 | 5955 | 14063 | -0.131 | -0.0639 | No | ||
186 | LATS2 | 11923 6928 | 14097 | -0.134 | -0.0645 | No | ||
187 | IKBKE | 67 | 14176 | -0.139 | -0.0676 | No | ||
188 | CDK9 | 14619 | 14177 | -0.139 | -0.0664 | No | ||
189 | ERBB2 | 8913 | 14207 | -0.142 | -0.0668 | No | ||
190 | CAMKK2 | 9870 | 14257 | -0.146 | -0.0682 | No | ||
191 | WNK3 | 24227 | 14319 | -0.151 | -0.0702 | No | ||
192 | MAST1 | 12143 | 14378 | -0.157 | -0.0720 | No | ||
193 | GMFB | 21861 | 14439 | -0.164 | -0.0739 | No | ||
194 | TRIB2 | 21102 | 14484 | -0.168 | -0.0749 | No | ||
195 | PRKG2 | 74 | 14506 | -0.170 | -0.0746 | No | ||
196 | MAP2K6 | 20614 1414 | 14512 | -0.170 | -0.0734 | No | ||
197 | CAMK2B | 20536 | 14588 | -0.178 | -0.0760 | No | ||
198 | ACVR1B | 4335 22353 | 14601 | -0.180 | -0.0751 | No | ||
199 | PINK1 | 12752 15703 | 14650 | -0.185 | -0.0761 | No | ||
200 | ERN1 | 8137 | 14698 | -0.190 | -0.0770 | No | ||
201 | GSK3B | 22761 | 14988 | -0.227 | -0.0908 | No | ||
202 | SOCS1 | 4522 | 15021 | -0.231 | -0.0906 | No | ||
203 | FASTK | 16589 3661 3478 3664 | 15066 | -0.236 | -0.0910 | No | ||
204 | DYRK1B | 18321 | 15125 | -0.244 | -0.0921 | No | ||
205 | WNK4 | 7644 | 15127 | -0.244 | -0.0900 | No | ||
206 | LMTK2 | 16631 | 15467 | -0.303 | -0.1059 | No | ||
207 | SRPK2 | 5513 | 15688 | -0.354 | -0.1149 | No | ||
208 | BRSK2 | 190 | 15781 | -0.373 | -0.1167 | No | ||
209 | PIM2 | 5249 9564 9565 | 15952 | -0.417 | -0.1224 | No | ||
210 | STAT1 | 3936 5524 | 15957 | -0.419 | -0.1190 | No | ||
211 | CD80 | 22758 | 16016 | -0.435 | -0.1185 | No | ||
212 | AKTIP | 4738 | 16046 | -0.444 | -0.1163 | No | ||
213 | PRKAA1 | 22520 | 16097 | -0.456 | -0.1151 | No | ||
214 | UHMK1 | 4038 4957 | 16132 | -0.467 | -0.1130 | No | ||
215 | F2 | 14524 | 16153 | -0.473 | -0.1100 | No | ||
216 | EIF2AK1 | 4869 | 16300 | -0.517 | -0.1136 | No | ||
217 | PXK | 26 | 16395 | -0.551 | -0.1140 | No | ||
218 | MAPK8 | 6459 | 16644 | -0.646 | -0.1220 | No | ||
219 | COL4A3BP | 3221 7522 | 16725 | -0.687 | -0.1204 | No | ||
220 | CDC42BPB | 20982 | 16817 | -0.728 | -0.1192 | No | ||
221 | PAK2 | 10310 5875 | 16924 | -0.783 | -0.1183 | No | ||
222 | ABI1 | 4300 | 16997 | -0.827 | -0.1151 | No | ||
223 | PMVK | 15539 | 17005 | -0.832 | -0.1084 | No | ||
224 | IKBKAP | 2540 6045 | 17104 | -0.879 | -0.1063 | No | ||
225 | ACVR1 | 4334 | 17118 | -0.886 | -0.0994 | No | ||
226 | DYRK3 | 5939 | 17650 | -1.148 | -0.1185 | No | ||
227 | AKT3 | 13739 982 | 17683 | -1.172 | -0.1103 | No | ||
228 | VRK2 | 947 20511 | 17714 | -1.192 | -0.1017 | No | ||
229 | CD81 | 8719 | 17724 | -1.201 | -0.0920 | No | ||
230 | AURKA | 14325 | 17767 | -1.228 | -0.0838 | No | ||
231 | PRDX4 | 24026 | 17839 | -1.277 | -0.0768 | No | ||
232 | NDUFS4 | 9452 5157 3173 | 17926 | -1.349 | -0.0699 | No | ||
233 | LCK | 15746 | 17991 | -1.398 | -0.0615 | No | ||
234 | ICK | 7135 12146 | 17995 | -1.401 | -0.0497 | No | ||
235 | MAPK6 | 19062 | 18044 | -1.445 | -0.0400 | No | ||
236 | PRKAG1 | 22135 | 18092 | -1.496 | -0.0298 | No | ||
237 | STK19 | 23016 1569 1508 | 18130 | -1.543 | -0.0187 | No | ||
238 | PRKD3 | 13252 7956 | 18136 | -1.550 | -0.0057 | No | ||
239 | STK3 | 7084 | 18277 | -1.738 | 0.0015 | No | ||
240 | F2R | 21386 | 18408 | -1.981 | 0.0113 | No |