Dataset | Set_04_transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB_repos |
Phenotype | phenotype_transDMpreB_versus_DMpreB.cls#transDMpreB_versus_DMpreB_repos |
Upregulated in class | DMpreB |
GeneSet | OXIDOREDUCTASE_ACTIVITY |
Enrichment Score (ES) | -0.57021475 |
Normalized Enrichment Score (NES) | -1.6854423 |
Nominal p-value | 0.0 |
FDR q-value | 0.0558085 |
FWER p-Value | 0.319 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | VCL | 22083 | 654 | 1.422 | -0.0228 | No | ||
2 | HAAO | 22885 1578 | 699 | 1.368 | -0.0129 | No | ||
3 | P4HA1 | 20017 | 850 | 1.205 | -0.0103 | No | ||
4 | NSDHL | 9489 9488 5198 | 913 | 1.151 | -0.0033 | No | ||
5 | MPO | 5116 20710 1324 | 949 | 1.107 | 0.0047 | No | ||
6 | ALDH2 | 16384 | 985 | 1.065 | 0.0124 | No | ||
7 | EGLN1 | 8504 18707 4298 | 1129 | 0.985 | 0.0135 | No | ||
8 | COX10 | 20408 | 1145 | 0.977 | 0.0214 | No | ||
9 | KMO | 13601 | 1270 | 0.880 | 0.0226 | No | ||
10 | BDH1 | 1714 7773 | 1324 | 0.847 | 0.0273 | No | ||
11 | RDH12 | 21227 | 1412 | 0.793 | 0.0297 | No | ||
12 | RDH11 | 21031 | 1614 | 0.673 | 0.0248 | No | ||
13 | TXNRD1 | 19923 | 1685 | 0.637 | 0.0267 | No | ||
14 | FRRS1 | 15438 | 1686 | 0.637 | 0.0324 | No | ||
15 | ETFA | 4292 8495 3155 | 1711 | 0.621 | 0.0367 | No | ||
16 | GPD2 | 4773 9014 | 1720 | 0.617 | 0.0418 | No | ||
17 | TXNRD2 | 22829 1649 | 1741 | 0.605 | 0.0461 | No | ||
18 | COX8A | 8777 | 1748 | 0.599 | 0.0512 | No | ||
19 | COX7A2L | 9819 | 1965 | 0.474 | 0.0437 | No | ||
20 | EGLN2 | 17920 | 1990 | 0.465 | 0.0466 | No | ||
21 | GPX2 | 9037 | 2054 | 0.438 | 0.0471 | No | ||
22 | HSD3B2 | 4873 4874 15229 4875 9126 | 2059 | 0.437 | 0.0508 | No | ||
23 | SC4MOL | 18867 | 2122 | 0.412 | 0.0511 | No | ||
24 | HMOX1 | 18565 | 2187 | 0.386 | 0.0511 | No | ||
25 | FXN | 23709 | 2285 | 0.358 | 0.0490 | No | ||
26 | GPD1 | 22361 | 2290 | 0.357 | 0.0520 | No | ||
27 | CAT | 14508 | 2329 | 0.347 | 0.0531 | No | ||
28 | XDH | 22897 | 2423 | 0.315 | 0.0508 | No | ||
29 | ACAD8 | 19192 3134 3032 | 2519 | 0.287 | 0.0482 | No | ||
30 | NCF2 | 14098 5151 9446 | 2677 | 0.254 | 0.0420 | No | ||
31 | POR | 16675 9601 | 2689 | 0.252 | 0.0436 | No | ||
32 | HSD17B11 | 3618 3533 8537 | 2799 | 0.233 | 0.0398 | No | ||
33 | IVD | 7102 | 2874 | 0.221 | 0.0378 | No | ||
34 | ALDH4A1 | 16011 | 2937 | 0.209 | 0.0363 | No | ||
35 | SOD2 | 23379 | 3188 | 0.174 | 0.0242 | No | ||
36 | ALOX12B | 20825 | 3209 | 0.171 | 0.0247 | No | ||
37 | OGDH | 9502 1412 | 3215 | 0.170 | 0.0259 | No | ||
38 | HPGD | 4867 | 3507 | 0.138 | 0.0113 | No | ||
39 | SUOX | 19590 | 3722 | 0.120 | 0.0007 | No | ||
40 | FMO2 | 7063 | 3770 | 0.117 | -0.0008 | No | ||
41 | PRODH | 5292 | 3818 | 0.113 | -0.0023 | No | ||
42 | DIO1 | 15814 2391 2414 | 3862 | 0.110 | -0.0037 | No | ||
43 | TDO2 | 12162 | 3881 | 0.109 | -0.0037 | No | ||
44 | COX4I2 | 14791 | 3926 | 0.107 | -0.0051 | No | ||
45 | CP | 4555 | 3935 | 0.106 | -0.0046 | No | ||
46 | JMJD2A | 10505 6058 | 3966 | 0.104 | -0.0053 | No | ||
47 | PLOD3 | 16666 | 4106 | 0.095 | -0.0120 | No | ||
48 | ACOX3 | 3612 16867 | 4230 | 0.088 | -0.0179 | No | ||
49 | MIOX | 22387 | 4267 | 0.086 | -0.0191 | No | ||
50 | HADH | 9075 15165 | 4279 | 0.086 | -0.0189 | No | ||
51 | IDH3B | 9299 | 4288 | 0.085 | -0.0186 | No | ||
52 | IDH3G | 24132 | 4380 | 0.081 | -0.0228 | No | ||
53 | ACADL | 8511 4056 | 4386 | 0.081 | -0.0223 | No | ||
54 | FMO1 | 8976 | 4400 | 0.080 | -0.0223 | No | ||
55 | CYP26A1 | 23871 3695 | 4425 | 0.079 | -0.0229 | No | ||
56 | SC5DL | 6165 | 4429 | 0.079 | -0.0224 | No | ||
57 | UQCRC1 | 10259 | 4631 | 0.071 | -0.0327 | No | ||
58 | WWOX | 13473 18458 18459 | 4746 | 0.067 | -0.0383 | No | ||
59 | HADHA | 16579 | 4929 | 0.061 | -0.0476 | No | ||
60 | AIFM2 | 3320 3407 20006 3317 | 5010 | 0.058 | -0.0515 | No | ||
61 | CYP27A1 | 4096 14222 | 5196 | 0.053 | -0.0610 | No | ||
62 | SDHD | 19125 | 5278 | 0.051 | -0.0650 | No | ||
63 | HSD3B1 | 15227 | 5474 | 0.047 | -0.0752 | No | ||
64 | ASPH | 2498 2460 2396 2370 2357 2502 2516 2375 2337 12276 2381 2454 7246 2480 2393 | 5572 | 0.044 | -0.0801 | No | ||
65 | ACOX2 | 21924 | 5654 | 0.043 | -0.0841 | No | ||
66 | GPX3 | 20880 | 5793 | 0.040 | -0.0912 | No | ||
67 | PHYH | 15124 | 5838 | 0.039 | -0.0933 | No | ||
68 | ALOX12 | 20372 | 5889 | 0.038 | -0.0957 | No | ||
69 | PDHA2 | 15153 | 5919 | 0.037 | -0.0969 | No | ||
70 | HSD17B4 | 23560 | 5978 | 0.036 | -0.0997 | No | ||
71 | PLOD2 | 19352 | 6046 | 0.035 | -0.1031 | No | ||
72 | ALDH3A1 | 20854 | 6209 | 0.032 | -0.1116 | No | ||
73 | ALDH1A1 | 8569 | 6305 | 0.031 | -0.1165 | No | ||
74 | ALDH1A2 | 19386 | 6309 | 0.031 | -0.1164 | No | ||
75 | CYP24A1 | 14328 | 6370 | 0.030 | -0.1194 | No | ||
76 | CYP1B1 | 4581 | 6434 | 0.029 | -0.1225 | No | ||
77 | ADH4 | 15405 | 6640 | 0.025 | -0.1335 | No | ||
78 | NOS1 | 9474 | 6665 | 0.025 | -0.1345 | No | ||
79 | HSD17B14 | 18245 | 6754 | 0.024 | -0.1391 | No | ||
80 | AOC3 | 8595 | 6904 | 0.021 | -0.1470 | No | ||
81 | NDUFS1 | 13940 | 6971 | 0.020 | -0.1504 | No | ||
82 | IMPDH1 | 17197 1131 | 7187 | 0.018 | -0.1620 | No | ||
83 | ALOX15 | 20370 | 7315 | 0.016 | -0.1687 | No | ||
84 | FDXR | 1451 20154 | 7658 | 0.012 | -0.1872 | No | ||
85 | NCF1 | 16354 | 7826 | 0.010 | -0.1962 | No | ||
86 | NOS3 | 16906 885 | 7918 | 0.009 | -0.2011 | No | ||
87 | RDH5 | 19599 8409 4214 4215 19587 | 8074 | 0.007 | -0.2095 | No | ||
88 | CYGB | 20139 | 8140 | 0.006 | -0.2130 | No | ||
89 | SDHA | 12436 | 8267 | 0.005 | -0.2198 | No | ||
90 | ALOX15B | 20397 | 8571 | 0.001 | -0.2363 | No | ||
91 | LDHC | 18235 2235 | 8640 | 0.000 | -0.2400 | No | ||
92 | DIO2 | 21014 2159 | 8884 | -0.002 | -0.2532 | No | ||
93 | TH | 17548 | 8917 | -0.003 | -0.2549 | No | ||
94 | ALDH9A1 | 14064 | 8980 | -0.004 | -0.2582 | No | ||
95 | AIFM1 | 2558 24161 | 9085 | -0.005 | -0.2638 | No | ||
96 | EPX | 20302 | 9142 | -0.006 | -0.2668 | No | ||
97 | DUOX2 | 14453 | 9174 | -0.006 | -0.2685 | No | ||
98 | CYP19A1 | 19112 | 9273 | -0.007 | -0.2737 | No | ||
99 | CYP7B1 | 15373 | 9279 | -0.007 | -0.2739 | No | ||
100 | P4HA2 | 20883 | 9543 | -0.011 | -0.2881 | No | ||
101 | ADH7 | 15408 | 9628 | -0.012 | -0.2926 | No | ||
102 | NQO1 | 18754 3836 | 9687 | -0.013 | -0.2956 | No | ||
103 | MTHFR | 5130 | 9735 | -0.014 | -0.2981 | No | ||
104 | ABP1 | 17455 4598 | 9755 | -0.014 | -0.2990 | No | ||
105 | ALDH1A3 | 17802 | 9918 | -0.016 | -0.3077 | No | ||
106 | CYP46A1 | 21158 | 9922 | -0.016 | -0.3077 | No | ||
107 | GCDH | 3913 18812 | 10113 | -0.018 | -0.3178 | No | ||
108 | SRD5A2 | 22896 | 10143 | -0.019 | -0.3193 | No | ||
109 | PAH | 19911 | 10312 | -0.021 | -0.3282 | No | ||
110 | DMGDH | 21585 | 10363 | -0.022 | -0.3307 | No | ||
111 | TXNDC2 | 22907 | 10502 | -0.024 | -0.3380 | No | ||
112 | TYR | 17763 | 10535 | -0.024 | -0.3396 | No | ||
113 | MTRR | 5568 5569 3180 | 10774 | -0.028 | -0.3523 | No | ||
114 | FADS1 | 23933 | 10835 | -0.028 | -0.3553 | No | ||
115 | DHRS2 | 22011 | 10877 | -0.029 | -0.3572 | No | ||
116 | NOX4 | 18196 | 10975 | -0.030 | -0.3622 | No | ||
117 | NDUFS7 | 19946 | 10999 | -0.031 | -0.3632 | No | ||
118 | ALDH7A1 | 23435 | 11074 | -0.032 | -0.3669 | No | ||
119 | CPOX | 1740 8780 | 11277 | -0.035 | -0.3776 | No | ||
120 | PDHB | 12670 7548 | 11347 | -0.036 | -0.3810 | No | ||
121 | FDX1 | 19117 | 11370 | -0.037 | -0.3819 | No | ||
122 | BBOX1 | 5010 9290 | 11371 | -0.037 | -0.3816 | No | ||
123 | GLDC | 23701 | 11418 | -0.038 | -0.3838 | No | ||
124 | CDO1 | 8731 | 11773 | -0.044 | -0.4026 | No | ||
125 | DHRS9 | 6308 2887 | 11904 | -0.047 | -0.4093 | No | ||
126 | MSRA | 8477 | 11942 | -0.048 | -0.4109 | No | ||
127 | LOX | 23438 | 12086 | -0.051 | -0.4182 | No | ||
128 | ALDH8A1 | 10690 20075 3393 | 12276 | -0.056 | -0.4280 | No | ||
129 | NOX1 | 24066 2622 | 12289 | -0.056 | -0.4281 | No | ||
130 | CYP8B1 | 18959 | 12332 | -0.057 | -0.4299 | No | ||
131 | GMPR | 21651 | 12338 | -0.057 | -0.4296 | No | ||
132 | DHRS3 | 15997 | 12406 | -0.059 | -0.4328 | No | ||
133 | GAPDHS | 4752 | 12606 | -0.065 | -0.4430 | No | ||
134 | BDH2 | 15413 | 12711 | -0.068 | -0.4480 | No | ||
135 | BCDO2 | 19124 | 12804 | -0.071 | -0.4524 | No | ||
136 | UGDH | 10249 | 12839 | -0.072 | -0.4536 | No | ||
137 | CYP1A2 | 19097 | 12978 | -0.077 | -0.4604 | No | ||
138 | HAO1 | 14418 | 13286 | -0.089 | -0.4763 | No | ||
139 | CYP11B2 | 24574 | 13311 | -0.090 | -0.4768 | No | ||
140 | MAOB | 24182 2556 | 13393 | -0.093 | -0.4804 | No | ||
141 | CYBA | 18720 | 13421 | -0.095 | -0.4810 | No | ||
142 | HGD | 22766 | 13463 | -0.097 | -0.4824 | No | ||
143 | CYP17A1 | 23651 | 13674 | -0.108 | -0.4928 | No | ||
144 | AOX1 | 14246 4090 | 13736 | -0.111 | -0.4952 | No | ||
145 | NDUFA13 | 7400 | 13927 | -0.122 | -0.5044 | No | ||
146 | PTGS1 | 2726 5316 15028 | 14120 | -0.135 | -0.5136 | No | ||
147 | CYB5R3 | 2313 22186 | 14163 | -0.138 | -0.5147 | No | ||
148 | IMPDH2 | 10730 | 14256 | -0.146 | -0.5184 | No | ||
149 | INDO | 9141 | 14258 | -0.146 | -0.5171 | No | ||
150 | COX11 | 20705 | 14311 | -0.151 | -0.5186 | No | ||
151 | BLVRB | 18328 | 14674 | -0.188 | -0.5366 | No | ||
152 | CYP39A1 | 1538 23232 | 14675 | -0.188 | -0.5349 | No | ||
153 | MDH1 | 1245 9400 | 14722 | -0.193 | -0.5357 | No | ||
154 | EHHADH | 22635 | 14802 | -0.202 | -0.5381 | No | ||
155 | MTHFD2 | 17100 | 14803 | -0.202 | -0.5363 | No | ||
156 | ALDH3B1 | 12569 23949 | 14816 | -0.204 | -0.5351 | No | ||
157 | COX7B | 7260 | 14837 | -0.207 | -0.5344 | No | ||
158 | LOXL2 | 8256 | 14925 | -0.219 | -0.5371 | No | ||
159 | ACADM | 15133 1800 | 14980 | -0.225 | -0.5381 | No | ||
160 | PPOX | 13761 4104 | 14996 | -0.228 | -0.5368 | No | ||
161 | CYCS | 8821 | 15141 | -0.247 | -0.5424 | No | ||
162 | GSR | 18634 | 15328 | -0.279 | -0.5501 | No | ||
163 | ALDH6A1 | 21025 | 15556 | -0.322 | -0.5595 | No | ||
164 | ETFB | 18279 | 15583 | -0.327 | -0.5580 | No | ||
165 | BCKDHB | 19365 | 15636 | -0.339 | -0.5578 | No | ||
166 | SARDH | 9646 | 15643 | -0.341 | -0.5550 | No | ||
167 | CYB561 | 20189 | 15712 | -0.358 | -0.5555 | No | ||
168 | CYB5R4 | 6475 19361 | 15776 | -0.372 | -0.5556 | No | ||
169 | IDH1 | 4894 | 15895 | -0.401 | -0.5584 | No | ||
170 | NNT | 3273 5181 9471 3238 | 15898 | -0.402 | -0.5549 | No | ||
171 | RDH10 | 8272 | 16180 | -0.481 | -0.5659 | Yes | ||
172 | AOC2 | 20658 1256 | 16187 | -0.483 | -0.5619 | Yes | ||
173 | ADH5 | 8554 15404 | 16262 | -0.501 | -0.5614 | Yes | ||
174 | DHCR7 | 17999 | 16296 | -0.516 | -0.5586 | Yes | ||
175 | SCD | 23662 | 16343 | -0.534 | -0.5563 | Yes | ||
176 | ACADVL | 20375 | 16345 | -0.535 | -0.5515 | Yes | ||
177 | ETFDH | 15313 | 16430 | -0.561 | -0.5511 | Yes | ||
178 | HADHB | 3514 10527 | 16465 | -0.574 | -0.5478 | Yes | ||
179 | ALDH5A1 | 21511 | 16482 | -0.581 | -0.5434 | Yes | ||
180 | COX5A | 19431 | 16505 | -0.589 | -0.5393 | Yes | ||
181 | DECR1 | 15937 | 16562 | -0.617 | -0.5368 | Yes | ||
182 | PYCR1 | 20111 | 16602 | -0.634 | -0.5333 | Yes | ||
183 | NDUFS8 | 23950 | 16721 | -0.685 | -0.5335 | Yes | ||
184 | GSTZ1 | 21193 | 16879 | -0.761 | -0.5352 | Yes | ||
185 | SRD5A1 | 13459 | 16882 | -0.762 | -0.5285 | Yes | ||
186 | COX5B | 4552 | 16899 | -0.772 | -0.5224 | Yes | ||
187 | PRDX3 | 23632 | 16915 | -0.777 | -0.5163 | Yes | ||
188 | HMOX2 | 22871 | 16939 | -0.791 | -0.5104 | Yes | ||
189 | CYC1 | 12348 | 17034 | -0.848 | -0.5079 | Yes | ||
190 | DEGS1 | 8850 | 17105 | -0.879 | -0.5038 | Yes | ||
191 | DLD | 2097 21090 | 17160 | -0.902 | -0.4987 | Yes | ||
192 | MSRB2 | 15111 | 17205 | -0.922 | -0.4928 | Yes | ||
193 | TSTA3 | 22253 | 17227 | -0.936 | -0.4855 | Yes | ||
194 | GLUD1 | 9022 | 17244 | -0.946 | -0.4779 | Yes | ||
195 | UQCRH | 12378 | 17279 | -0.965 | -0.4711 | Yes | ||
196 | PRDX2 | 3871 18542 5705 | 17340 | -0.997 | -0.4654 | Yes | ||
197 | NQO2 | 9469 3167 | 17353 | -0.999 | -0.4571 | Yes | ||
198 | BLVRA | 14868 | 17438 | -1.029 | -0.4524 | Yes | ||
199 | P4HB | 20115 | 17451 | -1.038 | -0.4438 | Yes | ||
200 | NDUFS2 | 4089 13760 | 17480 | -1.054 | -0.4358 | Yes | ||
201 | SPR | 17091 | 17531 | -1.078 | -0.4289 | Yes | ||
202 | ACADSB | 7358 | 17582 | -1.116 | -0.4215 | Yes | ||
203 | SURF1 | 14645 | 17597 | -1.122 | -0.4122 | Yes | ||
204 | NDUFS3 | 7553 12683 | 17602 | -1.123 | -0.4024 | Yes | ||
205 | ECSIT | 11248 | 17609 | -1.129 | -0.3926 | Yes | ||
206 | LDHA | 9269 | 17646 | -1.146 | -0.3842 | Yes | ||
207 | TXNDC1 | 13067 | 17710 | -1.188 | -0.3770 | Yes | ||
208 | TXNL1 | 7002 | 17759 | -1.226 | -0.3686 | Yes | ||
209 | TXN2 | 22227 | 17830 | -1.273 | -0.3610 | Yes | ||
210 | PRDX4 | 24026 | 17839 | -1.277 | -0.3499 | Yes | ||
211 | COX15 | 5931 | 17880 | -1.308 | -0.3404 | Yes | ||
212 | CBR1 | 22697 | 17902 | -1.322 | -0.3296 | Yes | ||
213 | H6PD | 15664 | 17919 | -1.337 | -0.3185 | Yes | ||
214 | NDUFS4 | 9452 5157 3173 | 17926 | -1.349 | -0.3067 | Yes | ||
215 | ME2 | 4202 | 17947 | -1.366 | -0.2955 | Yes | ||
216 | PHGDH | 10675 | 17950 | -1.367 | -0.2834 | Yes | ||
217 | UQCR | 12382 | 17992 | -1.399 | -0.2730 | Yes | ||
218 | CRYZL1 | 1644 12385 | 18023 | -1.429 | -0.2618 | Yes | ||
219 | HSD17B7 | 13768 | 18048 | -1.450 | -0.2501 | Yes | ||
220 | APEX1 | 22028 | 18051 | -1.453 | -0.2372 | Yes | ||
221 | MECR | 16059 | 18054 | -1.456 | -0.2242 | Yes | ||
222 | COX7A1 | 4554 | 18084 | -1.493 | -0.2124 | Yes | ||
223 | SOD1 | 9846 | 18108 | -1.514 | -0.2001 | Yes | ||
224 | GLRX2 | 12795 | 18164 | -1.580 | -0.1889 | Yes | ||
225 | NDUFA9 | 12288 | 18165 | -1.581 | -0.1747 | Yes | ||
226 | COX4I1 | 18444 | 18198 | -1.613 | -0.1619 | Yes | ||
227 | GRHPR | 16224 | 18322 | -1.818 | -0.1523 | Yes | ||
228 | GPX4 | 9038 | 18324 | -1.829 | -0.1359 | Yes | ||
229 | NUDT5 | 15121 | 18336 | -1.845 | -0.1200 | Yes | ||
230 | QDPR | 8482 | 18361 | -1.892 | -0.1043 | Yes | ||
231 | CBR3 | 22696 | 18393 | -1.941 | -0.0885 | Yes | ||
232 | HSD17B10 | 24226 | 18424 | -2.014 | -0.0721 | Yes | ||
233 | DHCR24 | 13228 7932 16159 | 18460 | -2.137 | -0.0548 | Yes | ||
234 | MGST3 | 13771 12349 | 18471 | -2.184 | -0.0357 | Yes | ||
235 | BCKDHA | 17925 | 18527 | -2.404 | -0.0171 | Yes | ||
236 | CYB5A | 23499 | 18537 | -2.442 | 0.0043 | Yes |