Dataset | Set_04_transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB_repos |
Phenotype | phenotype_transDMpreB_versus_DMpreB.cls#transDMpreB_versus_DMpreB_repos |
Upregulated in class | DMpreB |
GeneSet | V$NRF2_Q4 |
Enrichment Score (ES) | -0.39580312 |
Normalized Enrichment Score (NES) | -1.133013 |
Nominal p-value | 0.14212328 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ARHGAP8 | 4268 2196 | 8 | 3.396 | 0.0378 | No | ||
2 | BRD2 | 4735 8984 7628 | 51 | 2.773 | 0.0667 | No | ||
3 | MAST2 | 9423 | 112 | 2.400 | 0.0905 | No | ||
4 | BTK | 24061 | 118 | 2.378 | 0.1170 | No | ||
5 | CSNK1G2 | 19940 3418 | 246 | 2.062 | 0.1333 | No | ||
6 | EIF4G1 | 22818 | 252 | 2.051 | 0.1561 | No | ||
7 | SLC16A6 | 4186 | 292 | 1.944 | 0.1759 | No | ||
8 | TBL1X | 5628 | 472 | 1.665 | 0.1849 | No | ||
9 | BCL9L | 19475 | 495 | 1.633 | 0.2021 | No | ||
10 | BAZ2A | 4371 | 554 | 1.554 | 0.2165 | No | ||
11 | ABCD1 | 24305 | 712 | 1.345 | 0.2231 | No | ||
12 | MAP2K1 | 19082 | 767 | 1.285 | 0.2346 | No | ||
13 | PPP1R9B | 20698 | 947 | 1.108 | 0.2374 | No | ||
14 | HSPG2 | 4884 16023 | 1457 | 0.766 | 0.2184 | No | ||
15 | RAB6A | 18173 3905 | 1495 | 0.744 | 0.2248 | No | ||
16 | H3F3B | 4839 | 1606 | 0.676 | 0.2264 | No | ||
17 | TXNRD1 | 19923 | 1685 | 0.637 | 0.2293 | No | ||
18 | FTSJ3 | 20187 | 1733 | 0.610 | 0.2337 | No | ||
19 | PITPNC1 | 7759 | 1976 | 0.469 | 0.2258 | No | ||
20 | GPX2 | 9037 | 2054 | 0.438 | 0.2266 | No | ||
21 | LAMC1 | 13805 | 2145 | 0.401 | 0.2262 | No | ||
22 | ABCA2 | 15083 | 2556 | 0.279 | 0.2071 | No | ||
23 | NOTCH4 | 23277 9475 | 2649 | 0.260 | 0.2050 | No | ||
24 | ADCK4 | 13364 | 2740 | 0.243 | 0.2029 | No | ||
25 | CDH23 | 3369 19759 3442 | 2742 | 0.242 | 0.2056 | No | ||
26 | SFXN5 | 17090 | 2907 | 0.214 | 0.1991 | No | ||
27 | CD44 | 2881 2847 2893 4499 2724 | 3150 | 0.180 | 0.1880 | No | ||
28 | BACH1 | 8647 | 3151 | 0.179 | 0.1900 | No | ||
29 | SYTL1 | 15728 | 3256 | 0.164 | 0.1862 | No | ||
30 | ALDOA | 8572 | 3405 | 0.147 | 0.1798 | No | ||
31 | SNCG | 21878 | 3416 | 0.146 | 0.1809 | No | ||
32 | PDE4D | 10722 6235 | 3504 | 0.138 | 0.1778 | No | ||
33 | CSMD3 | 10735 7938 | 3626 | 0.129 | 0.1726 | No | ||
34 | PFN2 | 15337 1818 | 3777 | 0.116 | 0.1658 | No | ||
35 | DRP2 | 24254 | 3932 | 0.106 | 0.1587 | No | ||
36 | PKN3 | 15057 | 4001 | 0.102 | 0.1561 | No | ||
37 | PSMD4 | 15251 | 4024 | 0.100 | 0.1561 | No | ||
38 | MDFI | 22950 | 4339 | 0.082 | 0.1400 | No | ||
39 | SLC38A2 | 22149 2219 | 4413 | 0.080 | 0.1369 | No | ||
40 | CLDN15 | 16667 3572 | 4562 | 0.073 | 0.1297 | No | ||
41 | IDS | 9142 2617 | 4597 | 0.072 | 0.1287 | No | ||
42 | IL6 | 16895 | 4753 | 0.067 | 0.1210 | No | ||
43 | OGG1 | 17331 | 4763 | 0.066 | 0.1213 | No | ||
44 | LIMK1 | 16350 | 4789 | 0.065 | 0.1206 | No | ||
45 | MIA2 | 21262 | 4843 | 0.064 | 0.1185 | No | ||
46 | ATP6V0A1 | 8640 4424 1197 | 5141 | 0.055 | 0.1030 | No | ||
47 | CAPN6 | 24041 | 5289 | 0.051 | 0.0956 | No | ||
48 | ELA1 | 22127 | 5313 | 0.050 | 0.0949 | No | ||
49 | TLL1 | 10188 | 5448 | 0.047 | 0.0882 | No | ||
50 | CPNE8 | 22156 | 5455 | 0.047 | 0.0884 | No | ||
51 | EPHB2 | 4675 2440 8910 | 5497 | 0.046 | 0.0867 | No | ||
52 | TFPI2 | 17228 | 5562 | 0.045 | 0.0837 | No | ||
53 | CRYGS | 22628 | 5888 | 0.038 | 0.0665 | No | ||
54 | TNXB | 1557 8174 878 8175 | 5962 | 0.036 | 0.0630 | No | ||
55 | MCF2 | 24147 | 6003 | 0.036 | 0.0612 | No | ||
56 | NUDT11 | 24387 | 6211 | 0.032 | 0.0503 | No | ||
57 | ITM2B | 9192 4935 21753 | 6214 | 0.032 | 0.0506 | No | ||
58 | TIAL1 | 996 5753 | 6360 | 0.030 | 0.0430 | No | ||
59 | GAS2L1 | 8133 | 6743 | 0.024 | 0.0226 | No | ||
60 | KCNH3 | 9207 | 6764 | 0.024 | 0.0218 | No | ||
61 | LOXL4 | 23672 | 6916 | 0.021 | 0.0138 | No | ||
62 | F2RL2 | 21580 | 7073 | 0.019 | 0.0056 | No | ||
63 | LGI3 | 21967 | 7078 | 0.019 | 0.0056 | No | ||
64 | SOST | 20210 | 7341 | 0.016 | -0.0084 | No | ||
65 | NOG | 13663 | 7615 | 0.012 | -0.0231 | No | ||
66 | WNT2 | 17212 | 7705 | 0.011 | -0.0278 | No | ||
67 | CRYBA2 | 13920 | 7791 | 0.010 | -0.0323 | No | ||
68 | RDH5 | 19599 8409 4214 4215 19587 | 8074 | 0.007 | -0.0475 | No | ||
69 | APBA2BP | 14385 | 8199 | 0.005 | -0.0542 | No | ||
70 | FGF11 | 20383 | 8220 | 0.005 | -0.0552 | No | ||
71 | USP13 | 13047 | 8247 | 0.005 | -0.0566 | No | ||
72 | BNIP3 | 17581 | 8252 | 0.005 | -0.0567 | No | ||
73 | TFEC | 17213 | 8330 | 0.004 | -0.0609 | No | ||
74 | EDG1 | 15187 | 8396 | 0.003 | -0.0644 | No | ||
75 | CACNB2 | 4466 8678 | 8470 | 0.002 | -0.0683 | No | ||
76 | TBXAS1 | 17480 1105 | 8565 | 0.001 | -0.0734 | No | ||
77 | FGF12 | 1723 22621 | 8735 | -0.001 | -0.0825 | No | ||
78 | ESRRG | 6447 | 9088 | -0.005 | -0.1016 | No | ||
79 | ZIC1 | 19040 | 9236 | -0.007 | -0.1095 | No | ||
80 | SPTBN4 | 13471 1104 | 9245 | -0.007 | -0.1098 | No | ||
81 | PHLDA2 | 17545 | 9338 | -0.008 | -0.1147 | No | ||
82 | RAN | 5356 9691 | 9465 | -0.010 | -0.1214 | No | ||
83 | INHA | 14214 | 9587 | -0.011 | -0.1279 | No | ||
84 | FLNC | 4302 8510 | 9670 | -0.013 | -0.1322 | No | ||
85 | SYT2 | 14122 | 9697 | -0.013 | -0.1334 | No | ||
86 | GDF8 | 9411 | 9791 | -0.014 | -0.1383 | No | ||
87 | PRX | 3729 9628 | 10035 | -0.017 | -0.1513 | No | ||
88 | FOXN1 | 20337 | 10054 | -0.018 | -0.1521 | No | ||
89 | MASP1 | 1632 22626 | 10115 | -0.018 | -0.1551 | No | ||
90 | TREX1 | 10219 3111 | 10155 | -0.019 | -0.1570 | No | ||
91 | MNT | 20784 | 10331 | -0.021 | -0.1663 | No | ||
92 | MMRN2 | 4194 | 10687 | -0.026 | -0.1852 | No | ||
93 | SMPX | 24220 | 11165 | -0.034 | -0.2107 | No | ||
94 | MRPL32 | 7961 | 11213 | -0.034 | -0.2129 | No | ||
95 | PRDM1 | 19775 3337 | 11223 | -0.034 | -0.2130 | No | ||
96 | MYH14 | 17845 | 11234 | -0.034 | -0.2132 | No | ||
97 | MAPRE3 | 8301 | 11730 | -0.043 | -0.2395 | No | ||
98 | RHOH | 13226 | 11742 | -0.044 | -0.2396 | No | ||
99 | USP14 | 2001 23492 | 11806 | -0.045 | -0.2425 | No | ||
100 | RARG | 22113 | 11828 | -0.045 | -0.2432 | No | ||
101 | SLC26A1 | 16446 | 11925 | -0.047 | -0.2478 | No | ||
102 | LRP1B | 8249 | 12008 | -0.049 | -0.2517 | No | ||
103 | VCP | 11254 | 12012 | -0.049 | -0.2513 | No | ||
104 | RB1CC1 | 4486 14299 | 12028 | -0.049 | -0.2516 | No | ||
105 | HOXA3 | 9108 1075 | 12131 | -0.052 | -0.2565 | No | ||
106 | FCHSD1 | 6661 11435 | 12175 | -0.053 | -0.2583 | No | ||
107 | DMD | 24295 2647 | 12193 | -0.054 | -0.2586 | No | ||
108 | LMO4 | 15151 | 12217 | -0.054 | -0.2592 | No | ||
109 | CAPN12 | 18314 | 12638 | -0.066 | -0.2813 | No | ||
110 | DUSP13 | 21904 | 12696 | -0.068 | -0.2836 | No | ||
111 | MMP19 | 7191 | 12874 | -0.073 | -0.2924 | No | ||
112 | LAMA3 | 23620 2009 | 13027 | -0.079 | -0.2997 | No | ||
113 | YWHAG | 16339 | 13409 | -0.094 | -0.3193 | No | ||
114 | RBBP7 | 10887 6366 10886 | 13450 | -0.096 | -0.3204 | No | ||
115 | KCNA2 | 15458 | 13547 | -0.101 | -0.3245 | No | ||
116 | PLEC1 | 2273 2198 2205 2178 2230 22247 2213 2231 2295 2172 5263 2266 | 13573 | -0.103 | -0.3247 | No | ||
117 | EEF1A2 | 8880 14309 | 13886 | -0.120 | -0.3402 | No | ||
118 | CANX | 4474 | 13946 | -0.124 | -0.3420 | No | ||
119 | FGF1 | 1994 23447 | 14006 | -0.128 | -0.3438 | No | ||
120 | ETV5 | 22630 | 14139 | -0.137 | -0.3494 | No | ||
121 | ZIC4 | 5992 | 14154 | -0.138 | -0.3486 | No | ||
122 | APBA1 | 11483 | 14164 | -0.139 | -0.3476 | No | ||
123 | KCND1 | 4940 | 14170 | -0.139 | -0.3463 | No | ||
124 | FGF9 | 8966 | 14217 | -0.143 | -0.3471 | No | ||
125 | ADCYAP1 | 4348 | 14281 | -0.148 | -0.3489 | No | ||
126 | GPR21 | 15020 | 14321 | -0.151 | -0.3493 | No | ||
127 | BEX2 | 24055 | 14376 | -0.157 | -0.3505 | No | ||
128 | KIF5A | 9222 | 14413 | -0.161 | -0.3506 | No | ||
129 | BLVRB | 18328 | 14674 | -0.188 | -0.3626 | No | ||
130 | GTF2A1 | 2064 8187 8188 13512 | 14827 | -0.206 | -0.3685 | No | ||
131 | PER2 | 3940 13881 | 15008 | -0.229 | -0.3757 | No | ||
132 | UBE2L3 | 5818 22647 | 15040 | -0.233 | -0.3748 | No | ||
133 | SLC11A1 | 5189 9483 5190 | 15109 | -0.242 | -0.3757 | No | ||
134 | RABEP1 | 12016 1344 | 15172 | -0.251 | -0.3763 | No | ||
135 | ROM1 | 23751 | 15429 | -0.294 | -0.3868 | No | ||
136 | ABHD4 | 22021 | 15574 | -0.326 | -0.3910 | No | ||
137 | PSMD12 | 20621 | 15664 | -0.347 | -0.3919 | Yes | ||
138 | UBXD2 | 14150 | 15665 | -0.347 | -0.3880 | Yes | ||
139 | RGS2 | 5379 | 15678 | -0.350 | -0.3847 | Yes | ||
140 | LRP1 | 9284 | 15790 | -0.375 | -0.3865 | Yes | ||
141 | PIAS1 | 7126 | 15828 | -0.383 | -0.3842 | Yes | ||
142 | ITPKC | 17919 | 15940 | -0.414 | -0.3855 | Yes | ||
143 | WBP4 | 21741 | 15986 | -0.428 | -0.3832 | Yes | ||
144 | SMAD6 | 19083 | 15996 | -0.430 | -0.3788 | Yes | ||
145 | NR1D1 | 4650 20258 949 | 16000 | -0.431 | -0.3741 | Yes | ||
146 | XPOT | 13090 | 16192 | -0.484 | -0.3790 | Yes | ||
147 | TOMM70A | 6608 | 16274 | -0.507 | -0.3777 | Yes | ||
148 | CNTN6 | 17346 | 16356 | -0.538 | -0.3761 | Yes | ||
149 | PSMD7 | 18752 3825 | 16614 | -0.638 | -0.3828 | Yes | ||
150 | PSMC5 | 1348 20624 | 16737 | -0.692 | -0.3816 | Yes | ||
151 | ADAM15 | 15275 | 16836 | -0.739 | -0.3786 | Yes | ||
152 | SH3BGRL2 | 5601 | 16850 | -0.746 | -0.3710 | Yes | ||
153 | GADD45G | 21637 | 16902 | -0.773 | -0.3650 | Yes | ||
154 | IPO13 | 15784 | 16935 | -0.789 | -0.3579 | Yes | ||
155 | NR5A1 | 14597 | 17094 | -0.876 | -0.3566 | Yes | ||
156 | DTX2 | 16674 3488 | 17246 | -0.947 | -0.3541 | Yes | ||
157 | PAFAH1B1 | 1340 5220 9524 | 17349 | -0.998 | -0.3484 | Yes | ||
158 | PSMA3 | 9632 5298 | 17363 | -1.000 | -0.3379 | Yes | ||
159 | DCTN2 | 7635 12812 | 17391 | -1.007 | -0.3280 | Yes | ||
160 | ALS2 | 7882 13151 | 17484 | -1.055 | -0.3211 | Yes | ||
161 | ENO1 | 8903 | 17502 | -1.065 | -0.3100 | Yes | ||
162 | AKT3 | 13739 982 | 17683 | -1.172 | -0.3066 | Yes | ||
163 | LRRFIP2 | 3024 3071 19285 | 17787 | -1.243 | -0.2982 | Yes | ||
164 | TUBB | 22998 10237 | 17895 | -1.317 | -0.2892 | Yes | ||
165 | PSMA2 | 9631 | 17925 | -1.349 | -0.2756 | Yes | ||
166 | SQSTM1 | 9517 | 18049 | -1.452 | -0.2659 | Yes | ||
167 | SKP1A | 20889 | 18072 | -1.475 | -0.2505 | Yes | ||
168 | ATP1B1 | 4420 | 18129 | -1.539 | -0.2362 | Yes | ||
169 | MGST1 | 17254 | 18229 | -1.667 | -0.2228 | Yes | ||
170 | SEC24D | 15429 | 18236 | -1.676 | -0.2043 | Yes | ||
171 | BLMH | 20769 | 18403 | -1.972 | -0.1911 | Yes | ||
172 | NDRG2 | 21843 | 18409 | -1.986 | -0.1690 | Yes | ||
173 | ABCB6 | 13162 | 18428 | -2.033 | -0.1471 | Yes | ||
174 | TTC1 | 7342 | 18467 | -2.170 | -0.1247 | Yes | ||
175 | BAG2 | 13985 | 18497 | -2.247 | -0.1010 | Yes | ||
176 | UCHL1 | 16834 | 18526 | -2.404 | -0.0755 | Yes | ||
177 | PSMD2 | 10137 5724 | 18598 | -3.160 | -0.0438 | Yes | ||
178 | PSME4 | 8339 20934 | 18613 | -3.969 | 0.0002 | Yes |