Details for gene set HSA04810_REGULATION_OF_ACTIN

Table: GSEA Results Summary

Dataset	Set_04_transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB_repos
Phenotype	phenotype_transDMpreB_versus_DMpreB.cls#transDMpreB_versus_DMpreB_repos
Upregulated in class	transDMpreB
GeneSet	HSA04810_REGULATION_OF_ACTIN_CYTOSKELETON
Enrichment Score (ES)	0.5378721
Normalized Enrichment Score (NES)	1.5866159
Nominal p-value	0.0
FDR q-value	0.27389315
FWER p-Value	0.829

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	LIMK2	9278 1296	47	2.806	0.0326	Yes
2	SLC9A1	16053	96	2.468	0.0609	Yes
3	WAS	24193	99	2.439	0.0913	Yes
4	MYH9	2252 2244	109	2.414	0.1210	Yes
5	ACTN4	17905 1798 1983	116	2.388	0.1506	Yes
6	RAC2	22217	117	2.387	0.1804	Yes
7	IQGAP1	6619	136	2.288	0.2081	Yes
8	ITGB7	22112	191	2.180	0.2324	Yes
9	PIK3CG	6635	265	2.027	0.2538	Yes
10	ARPC1B	3512 8628	325	1.871	0.2741	Yes
11	PAK4	17909	396	1.777	0.2925	Yes
12	ROCK1	5386	409	1.746	0.3137	Yes
13	WASL	17203	501	1.629	0.3292	Yes
14	FGF13	4720 8963 2627	518	1.613	0.3485	Yes
15	VCL	22083	654	1.422	0.3589	Yes
16	PPP1R12A	3354 19886	668	1.402	0.3758	Yes
17	WASF2	6326	671	1.401	0.3932	Yes
18	ARPC2	14225	677	1.393	0.4104	Yes
19	RRAS	18256	752	1.300	0.4226	Yes
20	MAP2K1	19082	767	1.285	0.4380	Yes
21	MSN	5122	879	1.181	0.4467	Yes
22	CSK	8805	940	1.117	0.4574	Yes
23	MAPK3	6458 11170	961	1.090	0.4700	Yes
24	ARPC5L	15017	1060	1.013	0.4774	Yes
25	RAF1	17035	1186	0.942	0.4824	Yes
26	SOS2	21049	1331	0.845	0.4851	Yes
27	VAV1	23173	1340	0.841	0.4952	Yes
28	PTK2	22271	1498	0.741	0.4960	Yes
29	GNA13	20617	1502	0.738	0.5051	Yes
30	GNG12	4789	1518	0.728	0.5134	Yes
31	TIAM1	22547	1578	0.694	0.5188	Yes
32	MAP2K2	19933	1669	0.648	0.5221	Yes
33	ARAF	24367	1729	0.613	0.5265	Yes
34	ITGAL	9187	1788	0.569	0.5305	Yes
35	EGF	15169	1801	0.561	0.5369	Yes
36	ITGB2	19978	1901	0.507	0.5379	Yes
37	ARHGEF6	13297 13104	2444	0.307	0.5123	No
38	ROCK2	21309 5387	2496	0.295	0.5132	No
39	PXN	5339 3573	2545	0.281	0.5142	No
40	ITGA10	15493	2557	0.279	0.5171	No
41	PIP5K3	14234	2729	0.245	0.5108	No
42	CYFIP1	9814	2792	0.234	0.5104	No
43	FGF3	17997	2866	0.222	0.5092	No
44	RRAS2	12431	2893	0.217	0.5105	No
45	PDGFRB	23539	2909	0.214	0.5124	No
46	PIK3CD	9563	2973	0.204	0.5115	No
47	CFL2	2155 21069	3023	0.197	0.5113	No
48	FGF17	21757	3061	0.193	0.5118	No
49	ITGA6	4930	3269	0.163	0.5026	No
50	BDKRB1	19418	3347	0.153	0.5003	No
51	PAK1	9527	3601	0.130	0.4882	No
52	ITGB3	20631	3713	0.121	0.4837	No
53	PFN2	15337 1818	3777	0.116	0.4817	No
54	PFN3	7968	3812	0.114	0.4813	No
55	PIP5K1C	5250 19929	3843	0.112	0.4811	No
56	VAV2	5848 2670	3906	0.108	0.4791	No
57	CD14	23452	3922	0.107	0.4796	No
58	PFN1	9555	3931	0.106	0.4805	No
59	PPP1CC	9609 5283	4016	0.101	0.4772	No
60	SSH3	3709 10890	4039	0.100	0.4773	No
61	SSH1	10540	4114	0.095	0.4744	No
62	FGF18	4721 1351	4204	0.089	0.4707	No
63	MYL2	16713	4236	0.087	0.4701	No
64	MYL7	9437	4262	0.086	0.4699	No
65	FGD3	11399	4280	0.085	0.4700	No
66	ARHGEF7	3823	4485	0.076	0.4599	No
67	APC2	10704	4489	0.076	0.4607	No
68	FGF10	4719 8962	4595	0.072	0.4559	No
69	FGF5	16785	4618	0.071	0.4556	No
70	RAC3	20561	4683	0.069	0.4530	No
71	LIMK1	16350	4789	0.065	0.4481	No
72	ARPC4	12642	4857	0.063	0.4453	No
73	BDKRB2	21163	4876	0.063	0.4451	No
74	FGF8	23656	4879	0.063	0.4458	No
75	ITGA5	22105	4957	0.060	0.4423	No
76	MRAS	9409	5166	0.054	0.4317	No
77	PDGFA	5237	5187	0.054	0.4313	No
78	NCKAP1	6947	5339	0.050	0.4238	No
79	FGFR1	3789 8968	5469	0.047	0.4174	No
80	FGFR2	1917 4722 1119	5517	0.046	0.4154	No
81	FGF14	21716 3005 3463	5520	0.046	0.4158	No
82	SOS1	5476	5727	0.041	0.4052	No
83	ITGAX	18058	5813	0.040	0.4011	No
84	TMSB4X	24005	5836	0.039	0.4004	No
85	ITGA2B	9186	5847	0.039	0.4003	No
86	BAIAP2	449 4236	5879	0.038	0.3991	No
87	CDC42	4503 8722 4504 2465	5895	0.038	0.3988	No
88	PIK3R5	11507	5998	0.036	0.3937	No
89	ITGAV	4931	6021	0.036	0.3929	No
90	RHOA	8624 4409 4410	6560	0.027	0.3641	No
91	ARHGEF12	19156	6766	0.024	0.3533	No
92	FGF2	15608	6855	0.022	0.3488	No
93	FGF4	8964	6883	0.022	0.3476	No
94	WASF1	13514	6956	0.021	0.3439	No
95	ITGB6	14581 2809	6994	0.020	0.3422	No
96	CHRM4	14945	6996	0.020	0.3424	No
97	TIAM2	10759	7123	0.019	0.3358	No
98	FGFR3	8969 3566	7141	0.018	0.3351	No
99	MOS	16254	7388	0.015	0.3219	No
100	GSN	2784	7436	0.014	0.3196	No
101	CRK	4559 1249	7549	0.013	0.3137	No
102	FGF20	18892	7588	0.013	0.3118	No
103	MYLC2PL	16670	7624	0.012	0.3100	No
104	PIK3R1	3170	7780	0.010	0.3017	No
105	FGF11	20383	8220	0.005	0.2780	No
106	ITGA11	6677 11449	8300	0.004	0.2738	No
107	FGF7	8965	8584	0.001	0.2584	No
108	FGF12	1723 22621	8735	-0.001	0.2503	No
109	CHRM2	10840	8814	-0.002	0.2461	No
110	MYLK	22778 4213	8871	-0.002	0.2431	No
111	ITGA4	4929	8961	-0.003	0.2383	No
112	MYH10	8077	8967	-0.003	0.2381	No
113	CHRM5	10038	8995	-0.004	0.2367	No
114	PDGFB	22199 2311	9172	-0.006	0.2272	No
115	FGF16	24270	9187	-0.006	0.2265	No
116	MYL9	14767 2659	9251	-0.007	0.2232	No
117	PAK7	14417	9538	-0.011	0.2078	No
118	ARHGEF1	1952 18343 3996	9677	-0.013	0.2005	No
119	FGD1	24228	9726	-0.013	0.1980	No
120	ABI2	4037 6830	9877	-0.015	0.1901	No
121	CHRM3	21547	9913	-0.016	0.1884	No
122	FGF21	17830	10314	-0.021	0.1670	No
123	PDGFRA	16824	10927	-0.030	0.1342	No
124	ITGA7	19835	11089	-0.032	0.1258	No
125	MYH14	17845	11234	-0.034	0.1185	No
126	ITGAE	20791 1481 1397 1380 1278 1238 1359	11462	-0.038	0.1066	No
127	PIK3CA	9562	11493	-0.039	0.1055	No
128	ITGA3	20284	11505	-0.039	0.1054	No
129	EGFR	1329 20944	12205	-0.054	0.0681	No
130	PPP1CB	5282 3529 3504	12239	-0.055	0.0670	No
131	PAK3	9528	12282	-0.056	0.0655	No
132	CHRM1	23943	12322	-0.057	0.0641	No
133	NRAS	5191	12495	-0.061	0.0555	No
134	ITGAM	9188	12558	-0.063	0.0529	No
135	PIK3R2	18850	12662	-0.067	0.0482	No
136	GNA12	9023	12854	-0.073	0.0387	No
137	ITGA8	14685	12999	-0.078	0.0319	No
138	ARPC5	12580 7487	13211	-0.086	0.0215	No
139	ACTN2	21545	13310	-0.090	0.0173	No
140	FGF23	17275	13546	-0.101	0.0059	No
141	PIK3R3	5248	13606	-0.105	0.0040	No
142	ACTN3	23967 8540	13926	-0.122	-0.0118	No
143	FGF1	1994 23447	14006	-0.128	-0.0145	No
144	FGF9	8966	14217	-0.143	-0.0241	No
145	FGFR4	3226	14308	-0.151	-0.0271	No
146	FGF22	12468 7385	14687	-0.190	-0.0452	No
147	ITGB4	9669 159	14952	-0.222	-0.0567	No
148	CYFIP2	20485 8045	14966	-0.224	-0.0546	No
149	FN1	4091 4094 971 13929	15177	-0.253	-0.0629	No
150	ITGB5	4932	15363	-0.283	-0.0694	No
151	APC	4396 2022	15464	-0.302	-0.0710	No
152	VAV3	1774 1848 15443	15768	-0.369	-0.0828	No
153	CFL1	4516	15803	-0.378	-0.0799	No
154	MYLPF	18069	15833	-0.385	-0.0767	No
155	ITGB1	3872 18411	15843	-0.387	-0.0723	No
156	KRAS	9247	15861	-0.392	-0.0683	No
157	PIP5K1B	5251 1841	15951	-0.416	-0.0680	No
158	SSH2	6202	15972	-0.423	-0.0637	No
159	SCIN	21079	16068	-0.450	-0.0633	No
160	F2	14524	16153	-0.473	-0.0619	No
161	ITGA9	19280	16241	-0.496	-0.0604	No
162	ARPC3	12109	16258	-0.501	-0.0550	No
163	PPP1CA	9608 3756 914 909	16336	-0.531	-0.0525	No
164	RAC1	16302	16377	-0.547	-0.0479	No
165	PFN4	11798	16863	-0.753	-0.0647	No
166	PIP5K1A	23708	16908	-0.776	-0.0574	No
167	PAK2	10310 5875	16924	-0.783	-0.0484	No
168	HRAS	4868	17006	-0.832	-0.0424	No
169	PIK3CB	19030	17167	-0.904	-0.0398	No
170	CRKL	4560	17208	-0.926	-0.0304	No
171	RDX	9712 5371	17373	-1.002	-0.0267	No
172	MAPK1	1642 11167	17667	-1.160	-0.0281	No
173	DIAPH3	7117	17711	-1.189	-0.0155	No
174	BCAR1	18741	17751	-1.220	-0.0024	No
175	ARPC1A	3541 16628 3519	18395	-1.949	-0.0129	No
176	F2R	21386	18408	-1.981	0.0113	No