Details for gene set HSA00230_PURINE

Table: GSEA Results Summary

Dataset	Set_04_transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB_repos
Phenotype	phenotype_transDMpreB_versus_DMpreB.cls#transDMpreB_versus_DMpreB_repos
Upregulated in class	DMpreB
GeneSet	HSA00230_PURINE_METABOLISM
Enrichment Score (ES)	-0.5657734
Normalized Enrichment Score (NES)	-1.548237
Nominal p-value	0.0017636684
FDR q-value	0.21280041
FWER p-Value	0.909

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	POLD3	17742	204	2.147	0.0205	No
2	HPRT1	2655 24339 408	244	2.067	0.0487	No
3	PKM2	3642 9573	439	1.709	0.0633	No
4	POLR1A	9749 5393	745	1.304	0.0659	No
5	POLA2	23988	819	1.240	0.0802	No
6	AK2	8563 2479 16073	873	1.189	0.0947	No
7	POLE	16755	1140	0.981	0.0947	No
8	POLD1	17847	1169	0.959	0.1073	No
9	POLD4	12822	1404	0.798	0.1063	No
10	NT5C	20151	1883	0.516	0.0881	No
11	PRPS2	24003	1912	0.501	0.0939	No
12	PDE8A	18202	2417	0.317	0.0713	No
13	XDH	22897	2423	0.315	0.0756	No
14	PDE2A	18170	2430	0.312	0.0799	No
15	RRM1	18163	2497	0.295	0.0806	No
16	RRM2	5401 5400	2892	0.217	0.0625	No
17	NME1	9467	2961	0.206	0.0619	No
18	PDE7A	9544 1788	3212	0.170	0.0508	No
19	ECGF1	22160	3245	0.166	0.0515	No
20	CANT1	13304	3395	0.148	0.0457	No
21	PDE4D	10722 6235	3504	0.138	0.0418	No
22	POLR3A	21900	3508	0.137	0.0437	No
23	NT5E	19360 18702	3904	0.108	0.0239	No
24	AMPD1	5051	3916	0.107	0.0249	No
25	POLR2C	9750	4458	0.078	-0.0032	No
26	ENTPD6	4496 2678	4460	0.077	-0.0022	No
27	GDA	4764	4626	0.071	-0.0100	No
28	PDE6H	17257	4689	0.069	-0.0124	No
29	ITPA	9193	4759	0.066	-0.0151	No
30	ADCY8	22281	4797	0.065	-0.0162	No
31	NPR2	16230	4955	0.060	-0.0238	No
32	PAPSS2	6258	5386	0.049	-0.0463	No
33	POLE2	21053	5882	0.038	-0.0726	No
34	ADCY4	2980 21818	5954	0.036	-0.0759	No
35	PDE4C	8481	6098	0.034	-0.0831	No
36	ADCY9	22680	6166	0.033	-0.0862	No
37	ENTPD2	8713	6584	0.026	-0.1084	No
38	AMPD2	1931 15197	6692	0.025	-0.1138	No
39	PKLR	1850 15545	7037	0.020	-0.1321	No
40	POLR3K	12447 7372	7063	0.019	-0.1332	No
41	IMPDH1	17197 1131	7187	0.018	-0.1396	No
42	NT5C1B	21315	7311	0.016	-0.1460	No
43	POLE3	7200	7444	0.014	-0.1529	No
44	GUCY1A3	7216 12245 15310	7505	0.013	-0.1560	No
45	GUCY2F	24045	7762	0.010	-0.1697	No
46	ENTPD3	19266	8358	0.004	-0.2018	No
47	ENTPD8	12996	8370	0.004	-0.2024	No
48	PDE10A	23387	8440	0.003	-0.2061	No
49	NPR1	9480	8528	0.002	-0.2107	No
50	AK5	6042	8635	0.000	-0.2165	No
51	ALLC	21093 2130	8861	-0.002	-0.2286	No
52	GUCY1A2	19580	8869	-0.002	-0.2289	No
53	POLA1	24112	8962	-0.003	-0.2339	No
54	NT5M	8345 4175	9073	-0.005	-0.2398	No
55	PDE1C	5235	9189	-0.006	-0.2459	No
56	GUCY2C	1140 16954	9454	-0.010	-0.2600	No
57	POLR2B	16817	9610	-0.012	-0.2682	No
58	ENPP3	19803	9728	-0.013	-0.2744	No
59	RRM2B	6902 6903 11801	10432	-0.023	-0.3121	No
60	ADCY5	10312	10596	-0.025	-0.3205	No
61	PDE7B	19807	10626	-0.026	-0.3217	No
62	PDE11A	10805	10649	-0.026	-0.3225	No
63	PDE1A	9541 5234	10813	-0.028	-0.3309	No
64	ADK	3302 3454 8555	11121	-0.033	-0.3470	No
65	ADCY6	22139 2283 8551	11490	-0.039	-0.3664	No
66	ENTPD1	4495	11525	-0.039	-0.3676	No
67	POLR3H	13460 8135	11584	-0.041	-0.3702	No
68	PDE4A	3037 19542 3083 3023	11997	-0.049	-0.3917	No
69	POLR2A	5394	12113	-0.052	-0.3972	No
70	PRIM1	19847	12164	-0.053	-0.3991	No
71	DGUOK	17099 1041	12229	-0.055	-0.4018	No
72	PDE9A	23301	12232	-0.055	-0.4011	No
73	GMPR	21651	12338	-0.057	-0.4059	No
74	AK1	4363	12500	-0.061	-0.4137	No
75	PDE6G	20119	12577	-0.064	-0.4169	No
76	PDE5A	15431	12802	-0.071	-0.4280	No
77	AMPD3	4383 2110	13060	-0.080	-0.4407	No
78	ADCY7	8552 448	13118	-0.082	-0.4426	No
79	PDE8B	5756	13249	-0.087	-0.4483	No
80	GUCY1B3	15311	13256	-0.087	-0.4474	No
81	NUDT9	7897	13302	-0.090	-0.4485	No
82	ADCY2	21412	13602	-0.104	-0.4631	No
83	PDE3B	5236	13786	-0.114	-0.4714	No
84	IMPDH2	10730	14256	-0.146	-0.4946	No
85	GMPR2	2711	14558	-0.175	-0.5083	No
86	NME7	926 4101 14070 3986 3946 931	14664	-0.187	-0.5112	No
87	AK3L1	8564	14724	-0.193	-0.5116	No
88	PNPT1	20936	14928	-0.219	-0.5194	No
89	ADCY3	21329 894	15106	-0.241	-0.5254	No
90	PAICS	16820	15673	-0.349	-0.5509	No
91	RFC5	13005 7791	15700	-0.356	-0.5471	No
92	PDE4B	9543	15910	-0.406	-0.5524	No
93	POLE4	12441	16004	-0.432	-0.5511	No
94	POLR2E	3325 19699	16276	-0.508	-0.5583	Yes
95	GART	22543 1754	16281	-0.510	-0.5511	Yes
96	PPAT	6081	16471	-0.577	-0.5528	Yes
97	ENPP1	19804	16584	-0.626	-0.5497	Yes
98	PDE6D	13897 3945	16796	-0.717	-0.5506	Yes
99	ENTPD5	4497	16843	-0.741	-0.5422	Yes
100	ENTPD4	7449	16858	-0.750	-0.5320	Yes
101	PAPSS1	15419	17035	-0.850	-0.5290	Yes
102	POLR2J	16672	17132	-0.889	-0.5211	Yes
103	ADSL	4358	17255	-0.952	-0.5138	Yes
104	ATIC	14231 3968	17439	-1.030	-0.5086	Yes
105	ADSSL1	21136 2087	17492	-1.059	-0.4958	Yes
106	ZNRD1	1491 22987	17540	-1.081	-0.4825	Yes
107	POLR3B	12875	17620	-1.135	-0.4701	Yes
108	POLD2	20537	17687	-1.174	-0.4565	Yes
109	POLR2I	12839	17691	-1.175	-0.4394	Yes
110	POLR1B	14857	17713	-1.191	-0.4231	Yes
111	NT5C2	3768 8052	17752	-1.221	-0.4072	Yes
112	NUDT2	16239	17821	-1.266	-0.3923	Yes
113	PRPS1	24233	17827	-1.272	-0.3739	Yes
114	ADA	2703 14361	17876	-1.307	-0.3573	Yes
115	DCK	16808	17881	-1.308	-0.3384	Yes
116	FHIT	21920	17890	-1.314	-0.3195	Yes
117	GMPS	15578	18028	-1.431	-0.3060	Yes
118	GUK1	20432	18041	-1.442	-0.2854	Yes
119	APRT	8620	18225	-1.660	-0.2710	Yes
120	NME6	3139 19297	18231	-1.669	-0.2468	Yes
121	NT5C3	17136	18251	-1.698	-0.2229	Yes
122	POLR1D	3593 3658 16623	18284	-1.749	-0.1990	Yes
123	NME2	9468	18309	-1.791	-0.1740	Yes
124	POLR2H	10888	18321	-1.818	-0.1479	Yes
125	NME4	23065 1577	18334	-1.844	-0.1215	Yes
126	NUDT5	15121	18336	-1.845	-0.0945	Yes
127	POLR2G	23753	18407	-1.978	-0.0693	Yes
128	NP	22027 9597 5273 5274	18493	-2.234	-0.0411	Yes
129	POLR2K	9413	18599	-3.250	0.0009	Yes