Dataset | Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB |
Phenotype | phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB |
Upregulated in class | LMproB |
GeneSet | HYDROLASE_ACTIVITY__ACTING_ON_ESTER_BONDS |
Enrichment Score (ES) | -0.53614175 |
Normalized Enrichment Score (NES) | -1.5263829 |
Nominal p-value | 0.0 |
FDR q-value | 0.4025166 |
FWER p-Value | 0.999 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PTP4A3 | 22460 2304 | 192 | 2.305 | 0.0165 | No | ||
2 | MBD4 | 17033 | 242 | 2.119 | 0.0386 | No | ||
3 | PTPN6 | 17002 | 269 | 2.004 | 0.0606 | No | ||
4 | POP1 | 2214 7482 | 519 | 1.474 | 0.0642 | No | ||
5 | HAGH | 9020 | 911 | 1.012 | 0.0548 | No | ||
6 | PDE1B | 9542 | 947 | 0.996 | 0.0645 | No | ||
7 | PDE4B | 9543 | 957 | 0.993 | 0.0756 | No | ||
8 | MTMR3 | 7908 13193 | 1432 | 0.668 | 0.0577 | No | ||
9 | PLA2G4B | 14896 | 1603 | 0.579 | 0.0552 | No | ||
10 | PLD3 | 17917 | 1671 | 0.550 | 0.0580 | No | ||
11 | DBR1 | 19341 | 1708 | 0.533 | 0.0622 | No | ||
12 | RNASEH1 | 21302 | 1738 | 0.521 | 0.0667 | No | ||
13 | ISG20 | 18210 | 1804 | 0.496 | 0.0690 | No | ||
14 | USP21 | 13762 | 1953 | 0.434 | 0.0660 | No | ||
15 | NT5C2 | 3768 8052 | 1969 | 0.429 | 0.0702 | No | ||
16 | LYPLA3 | 18482 | 2084 | 0.386 | 0.0685 | No | ||
17 | ARSA | 4416 | 2240 | 0.343 | 0.0641 | No | ||
18 | GALNS | 11945 | 2400 | 0.298 | 0.0589 | No | ||
19 | OTUB2 | 7537 12654 | 2485 | 0.279 | 0.0576 | No | ||
20 | ACP2 | 4318 | 2548 | 0.263 | 0.0573 | No | ||
21 | PTPRM | 22904 | 2552 | 0.263 | 0.0602 | No | ||
22 | N4BP2 | 16837 | 2586 | 0.257 | 0.0614 | No | ||
23 | PDE4C | 8481 | 2700 | 0.231 | 0.0580 | No | ||
24 | APTX | 2455 7291 | 2842 | 0.207 | 0.0527 | No | ||
25 | CTDP1 | 23399 1969 | 2869 | 0.203 | 0.0537 | No | ||
26 | RPP38 | 14698 | 2895 | 0.200 | 0.0547 | No | ||
27 | PTPRO | 1093 17256 | 2962 | 0.192 | 0.0533 | No | ||
28 | AOAH | 11296 | 2967 | 0.191 | 0.0554 | No | ||
29 | POP4 | 7261 | 3046 | 0.180 | 0.0532 | No | ||
30 | DFFA | 4627 | 3109 | 0.173 | 0.0519 | No | ||
31 | PTPLA | 11403 6636 14680 | 3177 | 0.164 | 0.0501 | No | ||
32 | PRDX6 | 4389 8596 | 3335 | 0.147 | 0.0433 | No | ||
33 | DUSP7 | 10661 | 3348 | 0.145 | 0.0444 | No | ||
34 | MAP1S | 11279 | 3496 | 0.131 | 0.0379 | No | ||
35 | PTPRA | 14844 | 3501 | 0.131 | 0.0392 | No | ||
36 | DNASE1L1 | 24128 | 3513 | 0.130 | 0.0401 | No | ||
37 | NT5E | 19360 18702 | 3552 | 0.126 | 0.0395 | No | ||
38 | FEN1 | 8961 | 3604 | 0.122 | 0.0382 | No | ||
39 | PTEN | 5305 | 3651 | 0.119 | 0.0371 | No | ||
40 | PTPN1 | 5325 | 3722 | 0.113 | 0.0346 | No | ||
41 | PTPN5 | 17817 | 3739 | 0.112 | 0.0350 | No | ||
42 | PTP4A2 | 9659 2463 2518 5324 | 3769 | 0.111 | 0.0347 | No | ||
43 | PTPRS | 1507 1565 1602 22928 | 3776 | 0.111 | 0.0357 | No | ||
44 | PDE4A | 3037 19542 3083 3023 | 3793 | 0.109 | 0.0361 | No | ||
45 | INPP4B | 18557 | 3941 | 0.099 | 0.0293 | No | ||
46 | PDE7B | 19807 | 3945 | 0.099 | 0.0303 | No | ||
47 | PTPRD | 11554 5330 | 3961 | 0.098 | 0.0306 | No | ||
48 | PTPN21 | 21009 | 4100 | 0.091 | 0.0242 | No | ||
49 | PNLIPRP1 | 23835 | 4225 | 0.085 | 0.0184 | No | ||
50 | PLA2G2E | 16016 | 4229 | 0.084 | 0.0192 | No | ||
51 | PTPN7 | 11500 | 4257 | 0.083 | 0.0187 | No | ||
52 | PPP1R3C | 23688 | 4368 | 0.079 | 0.0137 | No | ||
53 | ACHE | 16665 | 4451 | 0.075 | 0.0101 | No | ||
54 | ARSB | 4415 439 | 4491 | 0.074 | 0.0088 | No | ||
55 | LPL | 9283 5003 | 4667 | 0.068 | 0.0001 | No | ||
56 | ENPP2 | 9548 | 5029 | 0.058 | -0.0189 | No | ||
57 | DUSP4 | 18632 3820 | 5036 | 0.058 | -0.0185 | No | ||
58 | DUSP8 | 9493 | 5223 | 0.053 | -0.0280 | No | ||
59 | SMPD1 | 18145 2658 | 5296 | 0.051 | -0.0313 | No | ||
60 | CES2 | 18505 | 5297 | 0.051 | -0.0307 | No | ||
61 | PTPRK | 5332 20066 | 5351 | 0.050 | -0.0330 | No | ||
62 | WRN | 5882 10315 | 5399 | 0.049 | -0.0350 | No | ||
63 | XRN2 | 2936 6302 2905 | 5458 | 0.047 | -0.0376 | No | ||
64 | ERN2 | 17651 | 5508 | 0.046 | -0.0397 | No | ||
65 | PTPRU | 15738 | 5638 | 0.044 | -0.0463 | No | ||
66 | DUSP13 | 21904 | 5876 | 0.039 | -0.0587 | No | ||
67 | BDKRB2 | 21163 | 5964 | 0.038 | -0.0630 | No | ||
68 | PLD2 | 20803 | 6057 | 0.036 | -0.0676 | No | ||
69 | PTPN2 | 23414 | 6121 | 0.035 | -0.0706 | No | ||
70 | RAD9A | 913 3674 910 23958 | 6163 | 0.034 | -0.0724 | No | ||
71 | TPTE | 3875 3866 10615 3777 | 6333 | 0.031 | -0.0812 | No | ||
72 | MTMR2 | 8069 3003 | 6512 | 0.028 | -0.0906 | No | ||
73 | CCKBR | 8706 | 6636 | 0.027 | -0.0970 | No | ||
74 | EDNRA | 18834 | 6641 | 0.027 | -0.0969 | No | ||
75 | PLCD1 | 18972 | 6685 | 0.026 | -0.0989 | No | ||
76 | PLA2G3 | 20968 | 6690 | 0.026 | -0.0988 | No | ||
77 | PDE1C | 5235 | 6711 | 0.026 | -0.0996 | No | ||
78 | PDE10A | 23387 | 6965 | 0.023 | -0.1131 | No | ||
79 | PTPRH | 11861 | 7089 | 0.021 | -0.1195 | No | ||
80 | PLA2G1B | 9581 | 7133 | 0.021 | -0.1216 | No | ||
81 | PLA1A | 1737 22594 | 7155 | 0.020 | -0.1225 | No | ||
82 | PTPRJ | 9664 | 7220 | 0.020 | -0.1258 | No | ||
83 | LYPLA1 | 4107 9580 | 7221 | 0.020 | -0.1256 | No | ||
84 | ACP1 | 4317 | 7375 | 0.018 | -0.1337 | No | ||
85 | AADAC | 15584 | 7430 | 0.017 | -0.1364 | No | ||
86 | PLA2G2D | 16018 | 7490 | 0.016 | -0.1394 | No | ||
87 | PLA2G2A | 16017 | 7527 | 0.016 | -0.1412 | No | ||
88 | MTMR7 | 12032 | 7674 | 0.014 | -0.1490 | No | ||
89 | CDKN3 | 16965 | 7698 | 0.014 | -0.1501 | No | ||
90 | PNLIP | 23830 | 7728 | 0.014 | -0.1515 | No | ||
91 | MINPP1 | 3663 5100 9389 3748 9388 | 8110 | 0.009 | -0.1721 | No | ||
92 | CES1 | 18789 | 8264 | 0.007 | -0.1804 | No | ||
93 | C3AR1 | 8668 | 8273 | 0.007 | -0.1807 | No | ||
94 | F2RL2 | 21580 | 8455 | 0.005 | -0.1905 | No | ||
95 | PLD1 | 15624 | 8473 | 0.005 | -0.1914 | No | ||
96 | PNPLA3 | 22406 | 8550 | 0.004 | -0.1954 | No | ||
97 | PFKFB1 | 9552 | 8573 | 0.004 | -0.1966 | No | ||
98 | PTPRG | 22097 3151 | 8637 | 0.003 | -0.2000 | No | ||
99 | GNS | 19865 | 8701 | 0.003 | -0.2034 | No | ||
100 | CASR | 22602 | 8753 | 0.002 | -0.2061 | No | ||
101 | RNASE2 | 16758 | 8877 | 0.001 | -0.2128 | No | ||
102 | PLCB2 | 5262 | 8945 | 0.000 | -0.2164 | No | ||
103 | DUSP12 | 13765 | 8990 | -0.000 | -0.2188 | No | ||
104 | PLA2G4C | 147 | 9011 | -0.000 | -0.2199 | No | ||
105 | PNLIPRP2 | 23836 | 9085 | -0.001 | -0.2239 | No | ||
106 | PTPRF | 5331 2545 | 9244 | -0.003 | -0.2324 | No | ||
107 | PTPN4 | 13856 | 9269 | -0.003 | -0.2337 | No | ||
108 | TREX2 | 24137 | 9295 | -0.003 | -0.2350 | No | ||
109 | DNASE2 | 8855 | 9430 | -0.005 | -0.2423 | No | ||
110 | DUSP3 | 1358 13022 | 9567 | -0.006 | -0.2496 | No | ||
111 | PTPN3 | 9661 | 9749 | -0.007 | -0.2593 | No | ||
112 | USP29 | 18398 | 10032 | -0.010 | -0.2746 | No | ||
113 | PPEF2 | 16481 | 10294 | -0.013 | -0.2886 | No | ||
114 | PPP2R2A | 3222 21774 | 10353 | -0.013 | -0.2916 | No | ||
115 | OGG1 | 17331 | 10363 | -0.014 | -0.2919 | No | ||
116 | PTPN11 | 5326 16391 9660 | 10601 | -0.016 | -0.3046 | No | ||
117 | PLCE1 | 13156 | 10699 | -0.018 | -0.3097 | No | ||
118 | PSPH | 16362 | 10810 | -0.019 | -0.3155 | No | ||
119 | CHRM5 | 10038 | 10814 | -0.019 | -0.3154 | No | ||
120 | NANP | 12511 | 10822 | -0.019 | -0.3156 | No | ||
121 | POP7 | 16329 | 10889 | -0.020 | -0.3190 | No | ||
122 | TREX1 | 10219 3111 | 11042 | -0.021 | -0.3270 | No | ||
123 | SULF1 | 6285 | 11193 | -0.023 | -0.3349 | No | ||
124 | PTPN12 | 16597 3502 3586 3665 | 11449 | -0.026 | -0.3484 | No | ||
125 | USP12 | 5825 5824 | 11541 | -0.028 | -0.3530 | No | ||
126 | PTPRR | 3436 19876 | 11549 | -0.028 | -0.3531 | No | ||
127 | PTPRT | 5333 | 11609 | -0.029 | -0.3560 | No | ||
128 | CHRM1 | 23943 | 11626 | -0.029 | -0.3565 | No | ||
129 | DFFB | 15654 | 11664 | -0.029 | -0.3582 | No | ||
130 | HIBCH | 14250 | 11764 | -0.031 | -0.3632 | No | ||
131 | USP5 | 17004 | 11813 | -0.031 | -0.3655 | No | ||
132 | PTPRN | 13914 | 11869 | -0.032 | -0.3681 | No | ||
133 | LIPG | 23407 | 11889 | -0.032 | -0.3687 | No | ||
134 | ACP5 | 19200 | 12089 | -0.035 | -0.3791 | No | ||
135 | DLG1 | 22793 1672 | 12221 | -0.037 | -0.3858 | No | ||
136 | PTPRE | 1662 18039 | 12225 | -0.037 | -0.3856 | No | ||
137 | CILP | 19404 | 12310 | -0.039 | -0.3897 | No | ||
138 | ACOT9 | 24221 | 12406 | -0.040 | -0.3944 | No | ||
139 | EXOSC7 | 19256 | 12409 | -0.040 | -0.3940 | No | ||
140 | PTPRB | 19875 | 12480 | -0.041 | -0.3973 | No | ||
141 | UCHL3 | 6956 | 12494 | -0.042 | -0.3976 | No | ||
142 | SMPD2 | 5462 | 12643 | -0.044 | -0.4051 | No | ||
143 | PTPRN2 | 9666 | 12738 | -0.046 | -0.4097 | No | ||
144 | ACOT12 | 21591 | 12825 | -0.047 | -0.4138 | No | ||
145 | DNASE1L2 | 960 23092 | 12934 | -0.049 | -0.4191 | No | ||
146 | CCR5 | 8754 4534 | 13005 | -0.051 | -0.4223 | No | ||
147 | PTPN14 | 14012 | 13133 | -0.054 | -0.4286 | No | ||
148 | EPM2A | 20090 | 13186 | -0.055 | -0.4308 | No | ||
149 | ENPP3 | 19803 | 13530 | -0.065 | -0.4487 | No | ||
150 | PDE1A | 9541 5234 | 13638 | -0.068 | -0.4537 | No | ||
151 | PPAP2B | 7503 16161 | 13642 | -0.068 | -0.4531 | No | ||
152 | STS | 5542 | 13650 | -0.068 | -0.4527 | No | ||
153 | LCK | 15746 | 13709 | -0.070 | -0.4550 | No | ||
154 | DUSP2 | 14865 | 13868 | -0.077 | -0.4627 | No | ||
155 | RAD50 | 1198 20460 | 14006 | -0.082 | -0.4692 | No | ||
156 | PLA2G5 | 9583 | 14165 | -0.088 | -0.4768 | No | ||
157 | PDE3A | 7045 | 14207 | -0.089 | -0.4780 | No | ||
158 | MGLL | 17368 1145 | 14328 | -0.095 | -0.4834 | No | ||
159 | PPAP2C | 6938 | 14376 | -0.097 | -0.4848 | No | ||
160 | ACOT11 | 2432 6836 | 14541 | -0.106 | -0.4925 | No | ||
161 | PTPN18 | 14279 | 14557 | -0.106 | -0.4921 | No | ||
162 | LIPE | 17927 | 14563 | -0.107 | -0.4911 | No | ||
163 | ERCC4 | 6927 11921 | 14641 | -0.111 | -0.4940 | No | ||
164 | PLA2G10 | 22658 | 14649 | -0.111 | -0.4931 | No | ||
165 | RPP40 | 21491 | 14691 | -0.114 | -0.4940 | No | ||
166 | PPAP2A | 21562 3258 3244 | 14767 | -0.118 | -0.4967 | No | ||
167 | IMPA1 | 12066 | 14851 | -0.124 | -0.4997 | No | ||
168 | LIPF | 23883 | 14890 | -0.127 | -0.5003 | No | ||
169 | USP53 | 5245 8283 | 14978 | -0.134 | -0.5035 | No | ||
170 | PDE4D | 10722 6235 | 15012 | -0.136 | -0.5037 | No | ||
171 | IDS | 9142 2617 | 15020 | -0.137 | -0.5025 | No | ||
172 | RNASE1 | 21845 | 15059 | -0.141 | -0.5029 | No | ||
173 | PPP2CB | 18636 | 15083 | -0.143 | -0.5025 | No | ||
174 | PTPN9 | 19434 | 15189 | -0.152 | -0.5064 | No | ||
175 | FBP2 | 21422 | 15282 | -0.162 | -0.5095 | No | ||
176 | EXO1 | 14035 4135 | 15317 | -0.165 | -0.5094 | No | ||
177 | CHRM3 | 21547 | 15339 | -0.168 | -0.5086 | No | ||
178 | SBF1 | 13420 | 15343 | -0.168 | -0.5068 | No | ||
179 | INPP5E | 14650 | 15471 | -0.184 | -0.5116 | No | ||
180 | APOC2 | 8616 | 15479 | -0.185 | -0.5098 | No | ||
181 | MIR16 | 17663 1354 | 15544 | -0.195 | -0.5110 | No | ||
182 | PPP1CA | 9608 3756 914 909 | 15565 | -0.198 | -0.5098 | No | ||
183 | PTPRC | 5327 9662 | 15705 | -0.217 | -0.5148 | No | ||
184 | G6PC | 20656 | 15935 | -0.258 | -0.5242 | No | ||
185 | BPNT1 | 4082 14015 | 16015 | -0.276 | -0.5253 | No | ||
186 | NT5C | 20151 | 16079 | -0.290 | -0.5253 | No | ||
187 | RPP30 | 23877 | 16216 | -0.323 | -0.5290 | No | ||
188 | CDC14B | 3227 5750 | 16305 | -0.347 | -0.5297 | No | ||
189 | MRE11A | 3014 19560 | 16396 | -0.372 | -0.5303 | No | ||
190 | DULLARD | 20816 | 16451 | -0.385 | -0.5287 | No | ||
191 | PPP5C | 17952 | 16458 | -0.387 | -0.5245 | No | ||
192 | PDE7A | 9544 1788 | 16673 | -0.458 | -0.5308 | Yes | ||
193 | PPM1A | 5279 9607 | 16712 | -0.471 | -0.5274 | Yes | ||
194 | PPM1G | 16571 | 16778 | -0.501 | -0.5250 | Yes | ||
195 | DUSP11 | 17086 7785 | 16805 | -0.514 | -0.5205 | Yes | ||
196 | PPP6C | 7491 | 16849 | -0.535 | -0.5165 | Yes | ||
197 | PLA2G6 | 22209 | 16867 | -0.541 | -0.5112 | Yes | ||
198 | NT5C3 | 17136 | 16967 | -0.577 | -0.5098 | Yes | ||
199 | SULF2 | 12988 | 16977 | -0.581 | -0.5035 | Yes | ||
200 | PDE2A | 18170 | 16983 | -0.583 | -0.4970 | Yes | ||
201 | PPM1D | 20721 | 17001 | -0.588 | -0.4910 | Yes | ||
202 | RAD1 | 22507 | 17025 | -0.599 | -0.4853 | Yes | ||
203 | NTHL1 | 23357 | 17128 | -0.645 | -0.4833 | Yes | ||
204 | CYCS | 8821 | 17152 | -0.657 | -0.4769 | Yes | ||
205 | DICER1 | 20989 | 17229 | -0.696 | -0.4729 | Yes | ||
206 | ACP6 | 12394 | 17250 | -0.710 | -0.4657 | Yes | ||
207 | ERCC1 | 1235 1045 1646 | 17286 | -0.728 | -0.4590 | Yes | ||
208 | DNASE1L3 | 21925 | 17330 | -0.757 | -0.4525 | Yes | ||
209 | PDE3B | 5236 | 17380 | -0.788 | -0.4460 | Yes | ||
210 | INPP5D | 14198 | 17449 | -0.839 | -0.4399 | Yes | ||
211 | PPP1R8 | 15730 | 17511 | -0.869 | -0.4331 | Yes | ||
212 | RNASEH2A | 12819 | 17549 | -0.890 | -0.4247 | Yes | ||
213 | CNP | 8760 | 17574 | -0.904 | -0.4154 | Yes | ||
214 | EXOSC2 | 15044 | 17827 | -1.065 | -0.4167 | Yes | ||
215 | PON2 | 11637 | 17838 | -1.074 | -0.4047 | Yes | ||
216 | ACOT8 | 14344 2749 | 17970 | -1.186 | -0.3980 | Yes | ||
217 | DLG7 | 21858 | 17978 | -1.190 | -0.3844 | Yes | ||
218 | IMPA2 | 4328 | 18005 | -1.214 | -0.3717 | Yes | ||
219 | DUSP6 | 19891 3399 | 18024 | -1.236 | -0.3582 | Yes | ||
220 | PDIA3 | 14888 | 18067 | -1.293 | -0.3454 | Yes | ||
221 | FBP1 | 21423 | 18126 | -1.384 | -0.3324 | Yes | ||
222 | CDC25B | 14841 | 18131 | -1.397 | -0.3163 | Yes | ||
223 | ERCC5 | 14255 4097 | 18138 | -1.409 | -0.3001 | Yes | ||
224 | RNASE6 | 13439 | 18142 | -1.414 | -0.2838 | Yes | ||
225 | TIMM50 | 17911 | 18190 | -1.498 | -0.2688 | Yes | ||
226 | PTPN22 | 1775 15470 | 18240 | -1.580 | -0.2530 | Yes | ||
227 | NME1 | 9467 | 18275 | -1.635 | -0.2358 | Yes | ||
228 | DUSP1 | 23061 | 18279 | -1.643 | -0.2167 | Yes | ||
229 | INPP1 | 13961 | 18283 | -1.645 | -0.1977 | Yes | ||
230 | PNKP | 4052 18258 | 18306 | -1.684 | -0.1792 | Yes | ||
231 | UCHL1 | 16834 | 18409 | -2.011 | -0.1613 | Yes | ||
232 | PPM1B | 5280 1567 5281 | 18460 | -2.231 | -0.1379 | Yes | ||
233 | PPT1 | 9613 | 18579 | -3.277 | -0.1060 | Yes | ||
234 | APEX1 | 22028 | 18588 | -3.582 | -0.0646 | Yes | ||
235 | TP53 | 20822 | 18609 | -5.657 | 0.0004 | Yes |