Dataset | Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB |
Phenotype | phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB |
Upregulated in class | LMproB |
GeneSet | V$USF_02 |
Enrichment Score (ES) | -0.5228686 |
Normalized Enrichment Score (NES) | -1.4576509 |
Nominal p-value | 0.0022222223 |
FDR q-value | 0.69599813 |
FWER p-Value | 0.971 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PICALM | 18191 | 149 | 2.592 | 0.0259 | No | ||
2 | DCTN4 | 12560 7474 | 373 | 1.724 | 0.0364 | No | ||
3 | GABARAP | 20815 | 688 | 1.206 | 0.0352 | No | ||
4 | SNX8 | 16314 | 785 | 1.114 | 0.0446 | No | ||
5 | DDIT3 | 19857 | 985 | 0.976 | 0.0466 | No | ||
6 | GRN | 20640 | 1012 | 0.952 | 0.0576 | No | ||
7 | GPX1 | 19310 | 1017 | 0.947 | 0.0698 | No | ||
8 | MAP4K1 | 18313 | 1096 | 0.895 | 0.0773 | No | ||
9 | GNB2 | 9026 | 1115 | 0.873 | 0.0878 | No | ||
10 | ZFYVE26 | 9999 | 1118 | 0.872 | 0.0991 | No | ||
11 | ATP6V1A | 8638 | 1248 | 0.780 | 0.1023 | No | ||
12 | MAX | 21034 | 1346 | 0.717 | 0.1065 | No | ||
13 | KBTBD2 | 17137 | 1478 | 0.639 | 0.1077 | No | ||
14 | EGLN2 | 17920 | 1539 | 0.609 | 0.1125 | No | ||
15 | SLC23A2 | 14421 | 1760 | 0.512 | 0.1073 | No | ||
16 | PIP5K1A | 23708 | 1874 | 0.470 | 0.1073 | No | ||
17 | NFX1 | 2475 | 1933 | 0.444 | 0.1100 | No | ||
18 | STK16 | 14216 | 2016 | 0.406 | 0.1108 | No | ||
19 | HIVEP1 | 8486 | 2160 | 0.364 | 0.1078 | No | ||
20 | SIRT1 | 19745 | 2187 | 0.356 | 0.1111 | No | ||
21 | TOPORS | 15920 | 2199 | 0.353 | 0.1151 | No | ||
22 | BRDT | 4327 | 2217 | 0.348 | 0.1188 | No | ||
23 | COMMD8 | 16518 | 2230 | 0.345 | 0.1226 | No | ||
24 | CD164 | 20046 | 2328 | 0.319 | 0.1216 | No | ||
25 | H2AFY | 21447 | 2361 | 0.308 | 0.1239 | No | ||
26 | TOP3A | 5792 | 2632 | 0.246 | 0.1124 | No | ||
27 | HOXB7 | 666 9110 | 2877 | 0.202 | 0.1019 | No | ||
28 | MDM1 | 3306 3370 3316 3405 3376 19870 3429 3398 3406 3428 3346 355 | 2995 | 0.188 | 0.0980 | No | ||
29 | MCAM | 3109 19479 | 3021 | 0.184 | 0.0990 | No | ||
30 | RAB3IL1 | 3723 13229 | 3118 | 0.172 | 0.0961 | No | ||
31 | DDX3X | 24379 | 3230 | 0.158 | 0.0921 | No | ||
32 | DUSP7 | 10661 | 3348 | 0.145 | 0.0877 | No | ||
33 | NDUFA7 | 12347 | 3395 | 0.141 | 0.0871 | No | ||
34 | ILF3 | 3110 3030 9176 | 3457 | 0.136 | 0.0855 | No | ||
35 | FEN1 | 8961 | 3604 | 0.122 | 0.0792 | No | ||
36 | SLC12A6 | 8413 2829 2874 | 3774 | 0.111 | 0.0715 | No | ||
37 | XPO1 | 4172 | 3925 | 0.101 | 0.0647 | No | ||
38 | ALDH6A1 | 21025 | 3930 | 0.100 | 0.0658 | No | ||
39 | LHFP | 24038 | 3984 | 0.097 | 0.0642 | No | ||
40 | DNMT3A | 2167 21330 | 4026 | 0.094 | 0.0632 | No | ||
41 | HOXA11 | 17146 | 4065 | 0.092 | 0.0623 | No | ||
42 | NCOA6 | 2876 14382 | 4235 | 0.084 | 0.0543 | No | ||
43 | ARMET | 19005 | 4707 | 0.067 | 0.0296 | No | ||
44 | PTMA | 9657 | 4722 | 0.066 | 0.0297 | No | ||
45 | DVL2 | 20813 | 4965 | 0.059 | 0.0174 | No | ||
46 | RHOQ | 23142 | 4991 | 0.059 | 0.0168 | No | ||
47 | RNF128 | 24236 2641 | 5179 | 0.054 | 0.0073 | No | ||
48 | DUSP8 | 9493 | 5223 | 0.053 | 0.0057 | No | ||
49 | FGF14 | 21716 3005 3463 | 5686 | 0.043 | -0.0188 | No | ||
50 | UBE2B | 10245 | 5750 | 0.042 | -0.0217 | No | ||
51 | SOX10 | 22211 | 5955 | 0.038 | -0.0322 | No | ||
52 | SSR1 | 4211 | 5969 | 0.038 | -0.0324 | No | ||
53 | NPTX1 | 20126 | 6039 | 0.037 | -0.0357 | No | ||
54 | CAPN6 | 24041 | 6357 | 0.031 | -0.0525 | No | ||
55 | IRS4 | 9183 4926 | 6462 | 0.029 | -0.0577 | No | ||
56 | LRP5 | 23948 9285 | 6503 | 0.029 | -0.0595 | No | ||
57 | TAC1 | 17526 19853 | 6608 | 0.027 | -0.0648 | No | ||
58 | NIT1 | 11293 933 | 6759 | 0.025 | -0.0726 | No | ||
59 | UBXD2 | 14150 | 6775 | 0.025 | -0.0731 | No | ||
60 | SYNPO2L | 7582 | 7006 | 0.022 | -0.0853 | No | ||
61 | SUMF1 | 17049 | 7038 | 0.022 | -0.0867 | No | ||
62 | TYR | 17763 | 7052 | 0.022 | -0.0871 | No | ||
63 | BDNF | 14926 2797 | 7063 | 0.021 | -0.0874 | No | ||
64 | HNRPD | 8645 | 7158 | 0.020 | -0.0922 | No | ||
65 | AP1S2 | 8423 4228 | 7235 | 0.019 | -0.0961 | No | ||
66 | PIK3R1 | 3170 | 7282 | 0.019 | -0.0983 | No | ||
67 | CPT1A | 23756 | 7334 | 0.018 | -0.1009 | No | ||
68 | SMCR8 | 53 | 7364 | 0.018 | -0.1022 | No | ||
69 | CRLF1 | 18588 | 7419 | 0.017 | -0.1049 | No | ||
70 | SLC17A2 | 10163 5744 | 7481 | 0.017 | -0.1080 | No | ||
71 | VNN1 | 20071 | 7664 | 0.014 | -0.1177 | No | ||
72 | HOXD10 | 14983 | 7860 | 0.012 | -0.1281 | No | ||
73 | GTF2A1 | 2064 8187 8188 13512 | 7942 | 0.011 | -0.1323 | No | ||
74 | RAB9A | 12113 7107 | 8099 | 0.009 | -0.1407 | No | ||
75 | APLN | 24164 | 8277 | 0.007 | -0.1502 | No | ||
76 | TAF6L | 5923 | 8301 | 0.007 | -0.1513 | No | ||
77 | GLA | 4362 | 8318 | 0.007 | -0.1521 | No | ||
78 | FOXD3 | 9088 | 8324 | 0.007 | -0.1523 | No | ||
79 | TOM1L2 | 10115 | 8335 | 0.007 | -0.1528 | No | ||
80 | UBXD3 | 15701 | 8380 | 0.006 | -0.1551 | No | ||
81 | PFKFB1 | 9552 | 8573 | 0.004 | -0.1654 | No | ||
82 | HOXC5 | 22340 | 8636 | 0.003 | -0.1687 | No | ||
83 | POGK | 7739 | 8639 | 0.003 | -0.1688 | No | ||
84 | FMR1 | 24321 | 8683 | 0.003 | -0.1711 | No | ||
85 | SEMA3A | 16919 | 8963 | 0.000 | -0.1862 | No | ||
86 | VLDLR | 5858 3763 912 3682 | 9237 | -0.003 | -0.2010 | No | ||
87 | NPM1 | 1196 | 9722 | -0.007 | -0.2272 | No | ||
88 | CARKL | 20789 | 10123 | -0.011 | -0.2487 | No | ||
89 | SLC1A7 | 16147 | 10384 | -0.014 | -0.2626 | No | ||
90 | NRIP3 | 17679 | 10417 | -0.014 | -0.2642 | No | ||
91 | CBX5 | 22108 4485 | 10531 | -0.015 | -0.2701 | No | ||
92 | SEC23IP | 18054 1701 | 10563 | -0.016 | -0.2716 | No | ||
93 | CLCN5 | 24204 | 10619 | -0.016 | -0.2743 | No | ||
94 | CALR | 18814 | 10708 | -0.018 | -0.2789 | No | ||
95 | STC2 | 5526 | 10885 | -0.020 | -0.2882 | No | ||
96 | BMP6 | 8659 | 10897 | -0.020 | -0.2885 | No | ||
97 | KCNE4 | 12196 | 11129 | -0.022 | -0.3007 | No | ||
98 | OMG | 5209 | 11603 | -0.028 | -0.3260 | No | ||
99 | C4A | 4460 8670 9832 8669 | 11654 | -0.029 | -0.3284 | No | ||
100 | TESK2 | 10504 | 11789 | -0.031 | -0.3352 | No | ||
101 | HNRPA1 | 9103 4860 | 11962 | -0.033 | -0.3441 | No | ||
102 | MTHFD1 | 2132 21238 | 12214 | -0.037 | -0.3572 | No | ||
103 | RAI14 | 22327 2191 | 12344 | -0.039 | -0.3637 | No | ||
104 | UROD | 15791 | 12402 | -0.040 | -0.3663 | No | ||
105 | EIF4E | 15403 1827 8890 | 12531 | -0.042 | -0.3727 | No | ||
106 | SLC39A5 | 3364 19596 | 12621 | -0.044 | -0.3769 | No | ||
107 | COQ4 | 15061 | 12717 | -0.045 | -0.3815 | No | ||
108 | GZMK | 21342 | 12786 | -0.047 | -0.3846 | No | ||
109 | HOXB5 | 20687 | 12998 | -0.051 | -0.3953 | No | ||
110 | LIN28 | 15723 | 13046 | -0.052 | -0.3972 | No | ||
111 | COPZ1 | 22338 | 13379 | -0.060 | -0.4144 | No | ||
112 | CREB5 | 10551 | 13540 | -0.065 | -0.4223 | No | ||
113 | ELAVL3 | 9136 | 13548 | -0.065 | -0.4218 | No | ||
114 | GTF2H1 | 4069 18236 | 13701 | -0.070 | -0.4291 | No | ||
115 | BTBD14B | 7344 7343 | 13719 | -0.071 | -0.4291 | No | ||
116 | TGFB2 | 5743 | 13826 | -0.075 | -0.4339 | No | ||
117 | HNRPH2 | 12085 7082 | 13869 | -0.077 | -0.4351 | No | ||
118 | LAMC2 | 4983 9266 13806 3975 | 14107 | -0.085 | -0.4469 | No | ||
119 | NEUROD1 | 14550 | 14275 | -0.092 | -0.4547 | No | ||
120 | MAT2A | 10553 10554 6099 | 14291 | -0.093 | -0.4543 | No | ||
121 | ZIC3 | 10430 | 14395 | -0.098 | -0.4586 | No | ||
122 | TNRC15 | 5971 | 14680 | -0.113 | -0.4725 | No | ||
123 | SUPV3L1 | 11677 | 14726 | -0.116 | -0.4735 | No | ||
124 | DHX35 | 14754 | 14871 | -0.125 | -0.4796 | No | ||
125 | GGN | 2472 1171 18312 | 14935 | -0.131 | -0.4813 | No | ||
126 | TCERG1 | 12075 2027 7068 | 15130 | -0.147 | -0.4899 | No | ||
127 | AKAP12 | 17600 | 15319 | -0.165 | -0.4980 | No | ||
128 | AATF | 20315 | 15610 | -0.205 | -0.5110 | No | ||
129 | LAMA3 | 23620 2009 | 15614 | -0.205 | -0.5085 | No | ||
130 | PTGES2 | 15038 | 15736 | -0.224 | -0.5121 | No | ||
131 | PER1 | 20827 | 15850 | -0.243 | -0.5151 | No | ||
132 | CYR61 | 9159 15145 9311 5024 | 15896 | -0.249 | -0.5142 | No | ||
133 | GPR65 | 21187 | 15962 | -0.263 | -0.5143 | No | ||
134 | TIMM8A | 24062 | 16028 | -0.279 | -0.5142 | No | ||
135 | MTCH2 | 14954 7120 | 16030 | -0.280 | -0.5105 | No | ||
136 | CTNS | 13503 | 16065 | -0.288 | -0.5086 | No | ||
137 | RPS28 | 12009 | 16221 | -0.324 | -0.5128 | No | ||
138 | ETV1 | 4688 8925 8924 | 16408 | -0.374 | -0.5180 | Yes | ||
139 | ATF7IP | 12028 13038 | 16441 | -0.384 | -0.5147 | Yes | ||
140 | DNAJB5 | 16236 | 16448 | -0.385 | -0.5099 | Yes | ||
141 | PPARGC1A | 16533 | 16531 | -0.405 | -0.5091 | Yes | ||
142 | ARPP-19 | 19379 | 16672 | -0.457 | -0.5107 | Yes | ||
143 | PPM1A | 5279 9607 | 16712 | -0.471 | -0.5066 | Yes | ||
144 | FZD6 | 22486 | 16718 | -0.472 | -0.5007 | Yes | ||
145 | ASNA1 | 18810 | 16732 | -0.481 | -0.4951 | Yes | ||
146 | RHEBL1 | 12781 | 16761 | -0.493 | -0.4902 | Yes | ||
147 | MRPL27 | 13573 | 16817 | -0.518 | -0.4864 | Yes | ||
148 | PLS3 | 8332 | 17057 | -0.612 | -0.4913 | Yes | ||
149 | EIF4B | 13279 7979 | 17068 | -0.619 | -0.4837 | Yes | ||
150 | RFC1 | 16527 | 17300 | -0.738 | -0.4866 | Yes | ||
151 | CLN3 | 17635 | 17395 | -0.797 | -0.4812 | Yes | ||
152 | UBE2L6 | 2768 12169 | 17472 | -0.848 | -0.4742 | Yes | ||
153 | SESN3 | 19561 | 17492 | -0.860 | -0.4640 | Yes | ||
154 | UTP14A | 13041 | 17548 | -0.890 | -0.4553 | Yes | ||
155 | CCAR1 | 7454 | 17567 | -0.898 | -0.4445 | Yes | ||
156 | ATF4 | 22417 2239 | 17706 | -0.997 | -0.4389 | Yes | ||
157 | RUNX1 | 4481 | 17719 | -1.000 | -0.4265 | Yes | ||
158 | PABPC1 | 5219 9522 9523 23572 | 17721 | -1.001 | -0.4134 | Yes | ||
159 | EIF3S10 | 4659 8887 | 17729 | -1.005 | -0.4006 | Yes | ||
160 | UBE4B | 2433 15672 | 17770 | -1.029 | -0.3893 | Yes | ||
161 | BLNK | 23681 3691 | 17772 | -1.030 | -0.3759 | Yes | ||
162 | PFDN2 | 9551 | 17801 | -1.048 | -0.3636 | Yes | ||
163 | ATP6V1C1 | 22487 12329 | 17982 | -1.192 | -0.3578 | Yes | ||
164 | RPS2 | 9279 | 18035 | -1.253 | -0.3442 | Yes | ||
165 | COMMD3 | 73 | 18092 | -1.333 | -0.3297 | Yes | ||
166 | SQSTM1 | 9517 | 18145 | -1.416 | -0.3140 | Yes | ||
167 | CDKN2C | 15806 2321 | 18193 | -1.505 | -0.2968 | Yes | ||
168 | ISGF3G | 2686 9184 | 18211 | -1.544 | -0.2775 | Yes | ||
169 | EPC1 | 2039 8907 2033 | 18251 | -1.584 | -0.2589 | Yes | ||
170 | OPRS1 | 9515 2402 | 18256 | -1.592 | -0.2382 | Yes | ||
171 | DUSP1 | 23061 | 18279 | -1.643 | -0.2179 | Yes | ||
172 | CHD4 | 8418 17281 4225 | 18312 | -1.692 | -0.1974 | Yes | ||
173 | SLC31A2 | 9827 | 18319 | -1.713 | -0.1753 | Yes | ||
174 | PRPS1 | 24233 | 18424 | -2.091 | -0.1536 | Yes | ||
175 | TCF12 | 10044 3125 | 18430 | -2.133 | -0.1259 | Yes | ||
176 | NUDC | 9495 | 18454 | -2.205 | -0.0982 | Yes | ||
177 | VPS16 | 2927 14845 2825 | 18489 | -2.315 | -0.0697 | Yes | ||
178 | UMPS | 22606 1760 | 18545 | -2.771 | -0.0364 | Yes | ||
179 | BAX | 17832 | 18570 | -3.065 | 0.0025 | Yes |