Dataset | Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB |
Phenotype | phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB |
Upregulated in class | DMproB |
GeneSet | V$SREBP_Q3 |
Enrichment Score (ES) | 0.5347817 |
Normalized Enrichment Score (NES) | 1.4409477 |
Nominal p-value | 0.0037807184 |
FDR q-value | 0.42677546 |
FWER p-Value | 0.993 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CEBPB | 8733 | 115 | 2.822 | 0.0362 | Yes | ||
2 | FCHSD2 | 18172 | 138 | 2.665 | 0.0751 | Yes | ||
3 | BCL11A | 4691 | 147 | 2.605 | 0.1139 | Yes | ||
4 | ITPR3 | 9195 | 166 | 2.502 | 0.1506 | Yes | ||
5 | TNFRSF19 | 21799 3033 | 224 | 2.206 | 0.1807 | Yes | ||
6 | BCL6 | 22624 | 290 | 1.956 | 0.2066 | Yes | ||
7 | ZFP36L1 | 4453 4454 | 356 | 1.756 | 0.2295 | Yes | ||
8 | APP | 4402 | 365 | 1.743 | 0.2553 | Yes | ||
9 | GADD45G | 21637 | 401 | 1.662 | 0.2784 | Yes | ||
10 | SIPA1 | 9820 | 435 | 1.612 | 0.3009 | Yes | ||
11 | SLC38A5 | 24388 | 455 | 1.576 | 0.3236 | Yes | ||
12 | MAN2B1 | 5077 | 476 | 1.546 | 0.3457 | Yes | ||
13 | REV3L | 20050 | 478 | 1.541 | 0.3689 | Yes | ||
14 | PDCD10 | 15314 | 578 | 1.366 | 0.3841 | Yes | ||
15 | TNNI2 | 18005 | 605 | 1.328 | 0.4026 | Yes | ||
16 | TNNT2 | 14113 | 643 | 1.269 | 0.4197 | Yes | ||
17 | DNMT3B | 2840 14785 | 714 | 1.178 | 0.4337 | Yes | ||
18 | SPI1 | 14949 | 863 | 1.040 | 0.4413 | Yes | ||
19 | GRN | 20640 | 1012 | 0.952 | 0.4476 | Yes | ||
20 | PHF12 | 11192 6483 | 1016 | 0.948 | 0.4617 | Yes | ||
21 | BAZ2A | 4371 | 1059 | 0.921 | 0.4733 | Yes | ||
22 | GNB2 | 9026 | 1115 | 0.873 | 0.4834 | Yes | ||
23 | ADD3 | 23812 3694 | 1117 | 0.873 | 0.4965 | Yes | ||
24 | RAB10 | 2090 21119 | 1129 | 0.862 | 0.5089 | Yes | ||
25 | SREBF2 | 5509 | 1395 | 0.690 | 0.5049 | Yes | ||
26 | VPREB3 | 19984 | 1496 | 0.627 | 0.5089 | Yes | ||
27 | HSPG2 | 4884 16023 | 1505 | 0.624 | 0.5179 | Yes | ||
28 | SRPR | 12525 7433 | 1613 | 0.573 | 0.5207 | Yes | ||
29 | TEAD2 | 18252 | 1733 | 0.524 | 0.5221 | Yes | ||
30 | BLCAP | 14371 | 1770 | 0.509 | 0.5279 | Yes | ||
31 | DTX1 | 16396 | 1786 | 0.502 | 0.5346 | Yes | ||
32 | SLC35A4 | 12588 | 1910 | 0.455 | 0.5348 | Yes | ||
33 | PCF11 | 121 | 2087 | 0.385 | 0.5310 | No | ||
34 | MID1 | 5097 5098 | 2729 | 0.226 | 0.4997 | No | ||
35 | RAB33A | 358 | 2829 | 0.209 | 0.4975 | No | ||
36 | AGER | 23276 1576 | 3017 | 0.185 | 0.4901 | No | ||
37 | RKHD1 | 10693 | 3027 | 0.184 | 0.4924 | No | ||
38 | SERPINI1 | 340 | 3083 | 0.176 | 0.4921 | No | ||
39 | TTC16 | 14618 | 3171 | 0.164 | 0.4898 | No | ||
40 | NDUFS8 | 23950 | 3289 | 0.152 | 0.4858 | No | ||
41 | HIPK1 | 4851 | 3414 | 0.139 | 0.4811 | No | ||
42 | LDLR | 4990 | 3590 | 0.122 | 0.4735 | No | ||
43 | DPT | 14069 | 3597 | 0.122 | 0.4750 | No | ||
44 | SLC6A4 | 20770 | 3646 | 0.119 | 0.4742 | No | ||
45 | KLF12 | 4960 2637 21732 9228 | 3693 | 0.116 | 0.4735 | No | ||
46 | APBB3 | 23454 | 3725 | 0.113 | 0.4735 | No | ||
47 | LGI3 | 21967 | 3764 | 0.111 | 0.4731 | No | ||
48 | MAP2K5 | 19088 | 3943 | 0.099 | 0.4649 | No | ||
49 | LRCH4 | 10544 6090 | 4068 | 0.092 | 0.4596 | No | ||
50 | ADRA1B | 4354 | 4149 | 0.088 | 0.4566 | No | ||
51 | NTRK3 | 2069 3652 3705 9492 | 4173 | 0.087 | 0.4567 | No | ||
52 | LHX1 | 4995 | 4180 | 0.087 | 0.4576 | No | ||
53 | GREM1 | 14485 | 4304 | 0.081 | 0.4522 | No | ||
54 | SMARCA1 | 24165 | 4325 | 0.080 | 0.4523 | No | ||
55 | TLX3 | 20501 | 4348 | 0.079 | 0.4523 | No | ||
56 | NRGN | 19176 | 4433 | 0.076 | 0.4489 | No | ||
57 | PDGFRB | 23539 | 4469 | 0.075 | 0.4481 | No | ||
58 | SV2B | 17795 | 4471 | 0.075 | 0.4492 | No | ||
59 | KCTD15 | 17864 | 4481 | 0.074 | 0.4498 | No | ||
60 | ZIC4 | 5992 | 4746 | 0.065 | 0.4365 | No | ||
61 | LBX1 | 98 23659 | 4791 | 0.064 | 0.4351 | No | ||
62 | WDR13 | 7859 13112 | 4841 | 0.062 | 0.4334 | No | ||
63 | AMHR2 | 8487 22345 | 4977 | 0.059 | 0.4270 | No | ||
64 | POU4F2 | 9603 5276 | 5087 | 0.056 | 0.4219 | No | ||
65 | SLITRK3 | 11816 | 5131 | 0.055 | 0.4204 | No | ||
66 | LRP8 | 16149 2425 | 5184 | 0.054 | 0.4184 | No | ||
67 | SEMA3B | 5422 | 5385 | 0.049 | 0.4083 | No | ||
68 | HOXA10 | 17145 989 | 5401 | 0.049 | 0.4082 | No | ||
69 | KCNJ1 | 3121 12110 | 5405 | 0.049 | 0.4088 | No | ||
70 | SH3KBP1 | 2631 12206 7189 | 5503 | 0.047 | 0.4042 | No | ||
71 | OTX2 | 9519 | 5718 | 0.042 | 0.3933 | No | ||
72 | DNAJC1 | 8854 | 5801 | 0.041 | 0.3894 | No | ||
73 | FBXO24 | 12918 3649 | 6049 | 0.036 | 0.3766 | No | ||
74 | GATA1 | 24196 | 6059 | 0.036 | 0.3766 | No | ||
75 | PRELP | 13833 | 6132 | 0.035 | 0.3733 | No | ||
76 | CDKL3 | 10016 5613 | 6291 | 0.032 | 0.3652 | No | ||
77 | CHN2 | 7652 | 6321 | 0.032 | 0.3641 | No | ||
78 | HYAL1 | 9139 | 6352 | 0.031 | 0.3629 | No | ||
79 | SLC7A11 | 6473 | 6447 | 0.030 | 0.3583 | No | ||
80 | NFATC4 | 22002 | 6517 | 0.028 | 0.3550 | No | ||
81 | PLA2G3 | 20968 | 6690 | 0.026 | 0.3460 | No | ||
82 | MTF1 | 5128 9421 | 7112 | 0.021 | 0.3235 | No | ||
83 | CACNA1D | 4464 8675 | 7635 | 0.015 | 0.2955 | No | ||
84 | PPP1R1B | 1342 20674 | 7694 | 0.014 | 0.2925 | No | ||
85 | GUCA2B | 15773 | 7705 | 0.014 | 0.2922 | No | ||
86 | EGFL9 | 23219 | 7777 | 0.013 | 0.2886 | No | ||
87 | HOXD10 | 14983 | 7860 | 0.012 | 0.2843 | No | ||
88 | PAX2 | 9530 24416 | 7937 | 0.011 | 0.2804 | No | ||
89 | MST1 | 9089 | 8071 | 0.010 | 0.2733 | No | ||
90 | UBXD3 | 15701 | 8380 | 0.006 | 0.2567 | No | ||
91 | PEG3 | 5240 | 8535 | 0.004 | 0.2484 | No | ||
92 | HCRTR1 | 15741 | 8599 | 0.004 | 0.2450 | No | ||
93 | DSG3 | 8866 | 8775 | 0.002 | 0.2356 | No | ||
94 | ADORA1 | 13831 | 8951 | 0.000 | 0.2261 | No | ||
95 | GNAO1 | 4785 3829 | 9038 | -0.001 | 0.2215 | No | ||
96 | PTHLH | 16931 | 9355 | -0.004 | 0.2044 | No | ||
97 | TNNI1 | 14116 | 9558 | -0.006 | 0.1935 | No | ||
98 | RHOA | 8624 4409 4410 | 9584 | -0.006 | 0.1923 | No | ||
99 | INPP4A | 3985 3935 11237 4085 | 9638 | -0.007 | 0.1895 | No | ||
100 | NOTCH2 | 15485 | 9671 | -0.007 | 0.1879 | No | ||
101 | SET | 7070 | 9773 | -0.008 | 0.1825 | No | ||
102 | ADCY4 | 2980 21818 | 10065 | -0.011 | 0.1669 | No | ||
103 | KCNMB1 | 9213 | 10118 | -0.011 | 0.1642 | No | ||
104 | EYA3 | 8936 2352 | 10210 | -0.012 | 0.1595 | No | ||
105 | FADS3 | 7214 | 10263 | -0.012 | 0.1569 | No | ||
106 | EIF5B | 10391 5963 | 10357 | -0.014 | 0.1520 | No | ||
107 | ZIC2 | 21927 | 10483 | -0.015 | 0.1455 | No | ||
108 | GRID2 | 4803 | 10930 | -0.020 | 0.1216 | No | ||
109 | DHH | 4629 | 11352 | -0.025 | 0.0992 | No | ||
110 | GFAP | 4774 | 11377 | -0.026 | 0.0983 | No | ||
111 | C1QTNF7 | 16852 | 11424 | -0.026 | 0.0962 | No | ||
112 | NFE2L3 | 17446 | 11590 | -0.028 | 0.0876 | No | ||
113 | HIF1A | 4850 | 11677 | -0.030 | 0.0834 | No | ||
114 | COL2A1 | 22145 4542 | 12005 | -0.034 | 0.0662 | No | ||
115 | LUM | 19896 | 12256 | -0.038 | 0.0532 | No | ||
116 | PAX7 | 15697 | 12429 | -0.041 | 0.0445 | No | ||
117 | HCN4 | 9080 | 12547 | -0.042 | 0.0388 | No | ||
118 | NEUROD2 | 20262 | 12583 | -0.043 | 0.0376 | No | ||
119 | GAP43 | 9001 | 12751 | -0.046 | 0.0292 | No | ||
120 | MYOG | 14129 | 12920 | -0.049 | 0.0208 | No | ||
121 | CA3 | 4476 8690 | 13259 | -0.057 | 0.0034 | No | ||
122 | GJB1 | 24276 | 13413 | -0.061 | -0.0040 | No | ||
123 | PRKACA | 18549 3844 | 13424 | -0.061 | -0.0036 | No | ||
124 | EMX2 | 23806 | 13616 | -0.067 | -0.0130 | No | ||
125 | MLLT6 | 20678 | 13824 | -0.075 | -0.0231 | No | ||
126 | PVRL1 | 3006 19482 12211 7192 | 13915 | -0.078 | -0.0267 | No | ||
127 | CACNA1A | 4461 | 13941 | -0.079 | -0.0269 | No | ||
128 | FXYD1 | 17874 85 | 14019 | -0.082 | -0.0298 | No | ||
129 | GRM6 | 45 | 14025 | -0.082 | -0.0289 | No | ||
130 | ATP6V0C | 8643 | 14050 | -0.083 | -0.0289 | No | ||
131 | RKHD3 | 18199 | 14080 | -0.084 | -0.0292 | No | ||
132 | PLCB3 | 23799 | 14117 | -0.086 | -0.0299 | No | ||
133 | SYTL2 | 18190 1539 3730 | 14183 | -0.088 | -0.0321 | No | ||
134 | CLSTN3 | 17006 | 14349 | -0.096 | -0.0396 | No | ||
135 | GFRA3 | 23469 | 14630 | -0.110 | -0.0531 | No | ||
136 | EN1 | 387 14155 | 14746 | -0.117 | -0.0576 | No | ||
137 | ZNF289 | 8060 13377 2750 8059 | 14886 | -0.127 | -0.0632 | No | ||
138 | MAP1A | 5124 | 14961 | -0.133 | -0.0652 | No | ||
139 | ST7 | 1054 17519 | 14973 | -0.134 | -0.0638 | No | ||
140 | UBE3A | 1209 1084 1830 | 15011 | -0.136 | -0.0637 | No | ||
141 | DDX6 | 3086 8844 | 15080 | -0.143 | -0.0653 | No | ||
142 | E2F1 | 14384 | 15142 | -0.148 | -0.0664 | No | ||
143 | IDH1 | 4894 | 15162 | -0.150 | -0.0651 | No | ||
144 | FNBP1 | 4732 | 15417 | -0.177 | -0.0762 | No | ||
145 | ANKRD25 | 6161 | 15441 | -0.180 | -0.0748 | No | ||
146 | PHF15 | 20467 8050 | 15540 | -0.195 | -0.0772 | No | ||
147 | HOXB4 | 20686 | 15769 | -0.228 | -0.0861 | No | ||
148 | HOXB2 | 8346 | 15804 | -0.235 | -0.0844 | No | ||
149 | ETV5 | 22630 | 16024 | -0.278 | -0.0921 | No | ||
150 | TXNDC9 | 13972 | 16044 | -0.282 | -0.0889 | No | ||
151 | FBS1 | 18067 | 16391 | -0.370 | -0.1021 | No | ||
152 | DNAJB5 | 16236 | 16448 | -0.385 | -0.0993 | No | ||
153 | HOXC4 | 4864 | 16454 | -0.386 | -0.0938 | No | ||
154 | TBCC | 23215 | 16457 | -0.386 | -0.0881 | No | ||
155 | EIF4G2 | 1908 8892 | 16710 | -0.470 | -0.0947 | No | ||
156 | DCTN1 | 1100 17392 | 16897 | -0.551 | -0.0964 | No | ||
157 | NT5C3 | 17136 | 16967 | -0.577 | -0.0915 | No | ||
158 | PPP1R10 | 6972 11960 6971 | 17069 | -0.619 | -0.0877 | No | ||
159 | PRKAG1 | 22135 | 17428 | -0.824 | -0.0947 | No | ||
160 | KPNB1 | 20274 | 17794 | -1.043 | -0.0987 | No | ||
161 | MRPS18B | 7365 | 17900 | -1.123 | -0.0875 | No | ||
162 | IVNS1ABP | 4384 4050 | 18039 | -1.265 | -0.0760 | No | ||
163 | ISGF3G | 2686 9184 | 18211 | -1.544 | -0.0620 | No | ||
164 | DPYSL2 | 3122 4561 8787 | 18242 | -1.581 | -0.0399 | No | ||
165 | YWHAQ | 10369 | 18378 | -1.909 | -0.0184 | No | ||
166 | ELOVL5 | 19373 | 18418 | -2.079 | 0.0107 | No |