Dataset | Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB |
Phenotype | phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB |
Upregulated in class | DMproB |
GeneSet | V$PEA3_Q6 |
Enrichment Score (ES) | 0.5423682 |
Normalized Enrichment Score (NES) | 1.4574022 |
Nominal p-value | 0.0035587188 |
FDR q-value | 0.4559913 |
FWER p-Value | 0.98 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | LPXN | 8399 | 10 | 5.292 | 0.0584 | Yes | ||
2 | SORL1 | 5474 | 64 | 3.314 | 0.0924 | Yes | ||
3 | VCAM1 | 5851 | 148 | 2.595 | 0.1167 | Yes | ||
4 | PICALM | 18191 | 149 | 2.592 | 0.1456 | Yes | ||
5 | FCGR3A | 8960 | 157 | 2.554 | 0.1736 | Yes | ||
6 | SLC2A3 | 17010 | 183 | 2.386 | 0.1988 | Yes | ||
7 | SELL | 9798 | 244 | 2.106 | 0.2190 | Yes | ||
8 | PTPN6 | 17002 | 269 | 2.004 | 0.2400 | Yes | ||
9 | ARF3 | 22137 | 325 | 1.869 | 0.2578 | Yes | ||
10 | ESRRA | 23802 | 350 | 1.777 | 0.2763 | Yes | ||
11 | HHEX | 23872 | 404 | 1.659 | 0.2919 | Yes | ||
12 | TMEM24 | 19150 | 421 | 1.633 | 0.3092 | Yes | ||
13 | CD84 | 14049 | 428 | 1.624 | 0.3270 | Yes | ||
14 | TRIM8 | 23824 | 432 | 1.616 | 0.3448 | Yes | ||
15 | SIPA1 | 9820 | 435 | 1.612 | 0.3626 | Yes | ||
16 | MARK2 | 8899 | 586 | 1.351 | 0.3695 | Yes | ||
17 | SRRM1 | 6958 | 588 | 1.348 | 0.3845 | Yes | ||
18 | TNNI2 | 18005 | 605 | 1.328 | 0.3984 | Yes | ||
19 | MAP4K2 | 6457 | 660 | 1.244 | 0.4093 | Yes | ||
20 | ADRBK1 | 23960 | 722 | 1.175 | 0.4191 | Yes | ||
21 | CDC14A | 15184 | 845 | 1.058 | 0.4242 | Yes | ||
22 | SPI1 | 14949 | 863 | 1.040 | 0.4349 | Yes | ||
23 | TRIM33 | 8236 13579 15472 8237 | 1036 | 0.935 | 0.4360 | Yes | ||
24 | NUMA1 | 18167 | 1046 | 0.927 | 0.4458 | Yes | ||
25 | RPS6KA4 | 23804 | 1047 | 0.927 | 0.4561 | Yes | ||
26 | SEC24C | 22086 | 1048 | 0.927 | 0.4664 | Yes | ||
27 | TCEB3 | 15707 | 1094 | 0.895 | 0.4740 | Yes | ||
28 | CTSS | 15505 | 1146 | 0.854 | 0.4807 | Yes | ||
29 | ELOVL1 | 16114 2484 12026 | 1220 | 0.799 | 0.4856 | Yes | ||
30 | POU2AF1 | 19455 | 1263 | 0.770 | 0.4919 | Yes | ||
31 | AKT3 | 13739 982 | 1301 | 0.740 | 0.4982 | Yes | ||
32 | FLI1 | 4729 | 1305 | 0.736 | 0.5062 | Yes | ||
33 | KCNAB2 | 15655 | 1306 | 0.736 | 0.5144 | Yes | ||
34 | PBXIP1 | 6028 | 1319 | 0.731 | 0.5219 | Yes | ||
35 | RPS3 | 6549 11295 | 1418 | 0.673 | 0.5240 | Yes | ||
36 | LAMC1 | 13805 | 1521 | 0.619 | 0.5254 | Yes | ||
37 | IRAK4 | 22379 11185 | 1524 | 0.616 | 0.5322 | Yes | ||
38 | SSBP3 | 2439 7814 2431 | 1597 | 0.581 | 0.5347 | Yes | ||
39 | CD53 | 4500 | 1816 | 0.493 | 0.5284 | Yes | ||
40 | LRMP | 17244 | 1916 | 0.452 | 0.5281 | Yes | ||
41 | NT5C2 | 3768 8052 | 1969 | 0.429 | 0.5300 | Yes | ||
42 | XPNPEP1 | 9310 3677 23645 | 2002 | 0.416 | 0.5329 | Yes | ||
43 | CD5 | 23741 | 2021 | 0.406 | 0.5365 | Yes | ||
44 | UNC93B1 | 23760 | 2099 | 0.382 | 0.5365 | Yes | ||
45 | POLD4 | 12822 | 2108 | 0.380 | 0.5403 | Yes | ||
46 | ZDHHC5 | 14547 | 2147 | 0.367 | 0.5424 | Yes | ||
47 | DPP3 | 7954 3746 | 2233 | 0.345 | 0.5416 | No | ||
48 | LTBR | 16993 | 2668 | 0.238 | 0.5207 | No | ||
49 | ELK4 | 8895 4664 3937 | 2672 | 0.238 | 0.5232 | No | ||
50 | ETV3 | 11294 | 2696 | 0.233 | 0.5246 | No | ||
51 | MR1 | 4837 | 2750 | 0.222 | 0.5242 | No | ||
52 | RAB39 | 19113 | 2822 | 0.210 | 0.5227 | No | ||
53 | CACNA1E | 4465 | 3196 | 0.162 | 0.5043 | No | ||
54 | PRDX6 | 4389 8596 | 3335 | 0.147 | 0.4984 | No | ||
55 | HIPK1 | 4851 | 3414 | 0.139 | 0.4957 | No | ||
56 | TCIRG1 | 3700 3752 23951 | 3421 | 0.139 | 0.4970 | No | ||
57 | IL18BP | 17730 | 3600 | 0.122 | 0.4887 | No | ||
58 | FEN1 | 8961 | 3604 | 0.122 | 0.4899 | No | ||
59 | PRF1 | 20011 | 3634 | 0.120 | 0.4896 | No | ||
60 | GPR120 | 23869 | 3664 | 0.117 | 0.4894 | No | ||
61 | FUT11 | 13084 | 4027 | 0.094 | 0.4708 | No | ||
62 | SELP | 14073 | 4265 | 0.083 | 0.4589 | No | ||
63 | RUNX3 | 8702 | 4292 | 0.081 | 0.4584 | No | ||
64 | VPS11 | 193 19148 | 4390 | 0.078 | 0.4540 | No | ||
65 | NRGN | 19176 | 4433 | 0.076 | 0.4526 | No | ||
66 | MFN2 | 15678 2417 | 4637 | 0.069 | 0.4423 | No | ||
67 | ITPKB | 3963 14028 | 4838 | 0.063 | 0.4322 | No | ||
68 | GRIN2B | 16957 | 5009 | 0.058 | 0.4236 | No | ||
69 | TIAL1 | 996 5753 | 5066 | 0.057 | 0.4212 | No | ||
70 | IPO7 | 6130 | 5090 | 0.056 | 0.4206 | No | ||
71 | LRFN4 | 23964 | 5546 | 0.046 | 0.3965 | No | ||
72 | SLC26A9 | 11560 980 4067 | 6081 | 0.036 | 0.3679 | No | ||
73 | SPRR4 | 15264 | 6187 | 0.034 | 0.3626 | No | ||
74 | SLC41A1 | 8269 | 6525 | 0.028 | 0.3447 | No | ||
75 | KAZALD1 | 4206 | 6595 | 0.027 | 0.3413 | No | ||
76 | LALBA | 22141 | 6802 | 0.025 | 0.3304 | No | ||
77 | MMRN2 | 4194 | 6810 | 0.024 | 0.3303 | No | ||
78 | CBL | 19154 | 6906 | 0.023 | 0.3254 | No | ||
79 | BDNF | 14926 2797 | 7063 | 0.021 | 0.3172 | No | ||
80 | NCAM1 | 5149 | 7350 | 0.018 | 0.3019 | No | ||
81 | CTBP2 | 17591 1137 | 7657 | 0.014 | 0.2854 | No | ||
82 | DMBT1 | 18050 | 7742 | 0.013 | 0.2810 | No | ||
83 | CENTD2 | 1758 18169 2284 | 7863 | 0.012 | 0.2747 | No | ||
84 | CD3E | 8714 | 8370 | 0.006 | 0.2473 | No | ||
85 | RNASEL | 6269 | 8372 | 0.006 | 0.2473 | No | ||
86 | CAPZA1 | 8687 | 8803 | 0.002 | 0.2241 | No | ||
87 | CAMK1D | 5977 2948 | 8821 | 0.002 | 0.2232 | No | ||
88 | CPNE8 | 22156 | 8852 | 0.001 | 0.2216 | No | ||
89 | FUCA1 | 16034 | 9253 | -0.003 | 0.1999 | No | ||
90 | GPA33 | 14066 | 9278 | -0.003 | 0.1987 | No | ||
91 | EXTL2 | 15440 | 9645 | -0.007 | 0.1789 | No | ||
92 | MARK1 | 5955 | 9717 | -0.007 | 0.1751 | No | ||
93 | PAX6 | 5223 | 10074 | -0.011 | 0.1560 | No | ||
94 | SV2A | 15498 12250 | 10177 | -0.012 | 0.1506 | No | ||
95 | RHOG | 17727 | 10542 | -0.016 | 0.1310 | No | ||
96 | PAFAH2 | 16045 2429 2483 | 10647 | -0.017 | 0.1256 | No | ||
97 | EHF | 4657 | 10672 | -0.017 | 0.1245 | No | ||
98 | ANKRD1 | 23689 | 11045 | -0.022 | 0.1046 | No | ||
99 | IL2RA | 4918 | 11136 | -0.023 | 0.0999 | No | ||
100 | BCL2L14 | 12412 | 11206 | -0.023 | 0.0965 | No | ||
101 | IVL | 15263 | 11558 | -0.028 | 0.0777 | No | ||
102 | PGM2L1 | 7712 | 11824 | -0.031 | 0.0637 | No | ||
103 | MMP7 | 19568 | 12030 | -0.034 | 0.0530 | No | ||
104 | ANK3 | 8591 3445 3304 3381 | 12288 | -0.038 | 0.0395 | No | ||
105 | ARHGDIB | 16950 | 12865 | -0.048 | 0.0088 | No | ||
106 | LIN28 | 15723 | 13046 | -0.052 | -0.0003 | No | ||
107 | KCNQ1 | 18001 4948 | 13225 | -0.056 | -0.0094 | No | ||
108 | PIK4CB | 1875 15511 | 13461 | -0.062 | -0.0214 | No | ||
109 | SLC35C1 | 14517 | 13656 | -0.069 | -0.0311 | No | ||
110 | CUGBP1 | 2805 8819 4576 2924 | 13682 | -0.069 | -0.0317 | No | ||
111 | GTF2H1 | 4069 18236 | 13701 | -0.070 | -0.0319 | No | ||
112 | LCK | 15746 | 13709 | -0.070 | -0.0315 | No | ||
113 | ADAMTS4 | 10791 | 14012 | -0.082 | -0.0470 | No | ||
114 | PLCB3 | 23799 | 14117 | -0.086 | -0.0516 | No | ||
115 | ITPR2 | 9194 | 14123 | -0.086 | -0.0510 | No | ||
116 | ST7L | 15465 1904 | 14229 | -0.090 | -0.0556 | No | ||
117 | DGKZ | 2836 14522 | 14279 | -0.092 | -0.0573 | No | ||
118 | PDGFD | 7756 | 14300 | -0.093 | -0.0573 | No | ||
119 | ZRANB1 | 6884 11702 | 14442 | -0.100 | -0.0638 | No | ||
120 | IL18 | 9172 | 14486 | -0.103 | -0.0650 | No | ||
121 | GAB2 | 1821 18184 2025 | 14724 | -0.116 | -0.0766 | No | ||
122 | TNFRSF19L | 11498 6727 6726 | 14731 | -0.116 | -0.0756 | No | ||
123 | ABLIM1 | 3717 3766 3679 | 14852 | -0.124 | -0.0807 | No | ||
124 | ELAVL4 | 15805 4889 9137 | 14877 | -0.126 | -0.0806 | No | ||
125 | ZNF289 | 8060 13377 2750 8059 | 14886 | -0.127 | -0.0796 | No | ||
126 | FGF23 | 17275 | 14942 | -0.131 | -0.0812 | No | ||
127 | LAG3 | 17000 | 14987 | -0.135 | -0.0820 | No | ||
128 | PUM1 | 8160 | 15051 | -0.141 | -0.0839 | No | ||
129 | SNCG | 21878 | 15123 | -0.146 | -0.0861 | No | ||
130 | SLAMF9 | 14045 | 15172 | -0.151 | -0.0870 | No | ||
131 | GATA3 | 9004 | 15431 | -0.179 | -0.0990 | No | ||
132 | RIN1 | 10349 | 15512 | -0.190 | -0.1012 | No | ||
133 | TYSND1 | 20007 | 15574 | -0.200 | -0.1023 | No | ||
134 | PTPRC | 5327 9662 | 15705 | -0.217 | -0.1070 | No | ||
135 | TAF5 | 23833 5934 3759 | 15805 | -0.235 | -0.1097 | No | ||
136 | CYR61 | 9159 15145 9311 5024 | 15896 | -0.249 | -0.1118 | No | ||
137 | GFI1 | 16451 | 16048 | -0.283 | -0.1168 | No | ||
138 | CD69 | 16979 8717 | 16322 | -0.351 | -0.1277 | No | ||
139 | XCL1 | 13781 | 16347 | -0.358 | -0.1250 | No | ||
140 | WASF2 | 6326 | 16526 | -0.404 | -0.1302 | No | ||
141 | PRKACB | 15140 | 16593 | -0.426 | -0.1290 | No | ||
142 | MAPKAPK2 | 13838 | 16658 | -0.450 | -0.1275 | No | ||
143 | DCLRE1C | 5976 10411 2858 2852 | 16709 | -0.469 | -0.1249 | No | ||
144 | SYTL1 | 15728 | 16739 | -0.483 | -0.1211 | No | ||
145 | CTSW | 23980 | 17218 | -0.691 | -0.1394 | No | ||
146 | GPD1 | 22361 | 17235 | -0.701 | -0.1324 | No | ||
147 | INPPL1 | 17733 3775 | 17500 | -0.863 | -0.1371 | No | ||
148 | NCF2 | 14098 5151 9446 | 17554 | -0.893 | -0.1301 | No | ||
149 | BLNK | 23681 3691 | 17772 | -1.030 | -0.1303 | No | ||
150 | SPATA6 | 16134 | 17826 | -1.065 | -0.1214 | No | ||
151 | VDAC2 | 22081 | 17873 | -1.097 | -0.1116 | No | ||
152 | SLC30A7 | 15186 | 18080 | -1.321 | -0.1081 | No | ||
153 | CAP1 | 8684 | 18133 | -1.398 | -0.0954 | No | ||
154 | CMAS | 17245 | 18139 | -1.413 | -0.0799 | No | ||
155 | CDKN2C | 15806 2321 | 18193 | -1.505 | -0.0661 | No | ||
156 | EPHA2 | 16006 | 18224 | -1.564 | -0.0503 | No | ||
157 | EPC1 | 2039 8907 2033 | 18251 | -1.584 | -0.0341 | No | ||
158 | NDUFS2 | 4089 13760 | 18485 | -2.303 | -0.0211 | No | ||
159 | LZTS2 | 10362 | 18516 | -2.524 | 0.0054 | No |