Dataset | Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB |
Phenotype | phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB |
Upregulated in class | DMproB |
GeneSet | V$MYB_Q3 |
Enrichment Score (ES) | 0.5287741 |
Normalized Enrichment Score (NES) | 1.4381126 |
Nominal p-value | 0.0017636684 |
FDR q-value | 0.41053343 |
FWER p-Value | 0.997 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CEBPB | 8733 | 115 | 2.822 | 0.0415 | Yes | ||
2 | ALDOA | 8572 | 129 | 2.714 | 0.0867 | Yes | ||
3 | GCAT | 11234 | 150 | 2.592 | 0.1294 | Yes | ||
4 | HEBP1 | 16961 | 188 | 2.333 | 0.1668 | Yes | ||
5 | KLF5 | 4456 | 328 | 1.857 | 0.1907 | Yes | ||
6 | ESRRA | 23802 | 350 | 1.777 | 0.2196 | Yes | ||
7 | GMFG | 1590 18319 | 358 | 1.753 | 0.2489 | Yes | ||
8 | HHEX | 23872 | 404 | 1.659 | 0.2745 | Yes | ||
9 | GTF3C2 | 7749 | 415 | 1.647 | 0.3018 | Yes | ||
10 | LIG4 | 11454 | 505 | 1.489 | 0.3221 | Yes | ||
11 | NDEL1 | 20399 | 717 | 1.177 | 0.3306 | Yes | ||
12 | ZNF148 | 5949 | 749 | 1.147 | 0.3483 | Yes | ||
13 | UBE2H | 5823 5822 | 939 | 1.000 | 0.3550 | Yes | ||
14 | NEDD8 | 21822 | 971 | 0.983 | 0.3699 | Yes | ||
15 | DDIT3 | 19857 | 985 | 0.976 | 0.3857 | Yes | ||
16 | SLC16A6 | 4186 | 1018 | 0.947 | 0.4000 | Yes | ||
17 | PIK3CG | 6635 | 1068 | 0.918 | 0.4129 | Yes | ||
18 | SECISBP2 | 21638 | 1099 | 0.889 | 0.4263 | Yes | ||
19 | FOXP1 | 4242 | 1101 | 0.886 | 0.4412 | Yes | ||
20 | CDCA3 | 17284 | 1114 | 0.876 | 0.4554 | Yes | ||
21 | CD68 | 4501 | 1124 | 0.867 | 0.4695 | Yes | ||
22 | FLI1 | 4729 | 1305 | 0.736 | 0.4722 | Yes | ||
23 | MXD3 | 21455 | 1495 | 0.627 | 0.4726 | Yes | ||
24 | TOB1 | 20703 | 1542 | 0.608 | 0.4804 | Yes | ||
25 | USP52 | 3397 19841 | 1586 | 0.586 | 0.4879 | Yes | ||
26 | DMD | 24295 2647 | 1652 | 0.559 | 0.4939 | Yes | ||
27 | CDK2 | 3438 3373 19592 3322 | 1686 | 0.541 | 0.5012 | Yes | ||
28 | BAP1 | 22057 | 1742 | 0.519 | 0.5070 | Yes | ||
29 | SF3B1 | 13954 | 1800 | 0.498 | 0.5124 | Yes | ||
30 | DSCAM | 1667 4641 22530 | 1807 | 0.496 | 0.5204 | Yes | ||
31 | OAZ2 | 9499 | 2011 | 0.409 | 0.5163 | Yes | ||
32 | ARHGEF6 | 13297 13104 | 2058 | 0.395 | 0.5205 | Yes | ||
33 | RASA3 | 5359 | 2184 | 0.358 | 0.5198 | Yes | ||
34 | SRGAP2 | 13836 17045 6433 17046 | 2262 | 0.337 | 0.5213 | Yes | ||
35 | GBA2 | 15898 | 2327 | 0.319 | 0.5232 | Yes | ||
36 | PREB | 6948 3628 | 2412 | 0.296 | 0.5237 | Yes | ||
37 | PRR3 | 22995 | 2478 | 0.281 | 0.5249 | Yes | ||
38 | SOX5 | 9850 1044 5480 16937 | 2494 | 0.277 | 0.5288 | Yes | ||
39 | PHF7 | 21890 | 2648 | 0.242 | 0.5246 | No | ||
40 | RGS2 | 5379 | 2651 | 0.241 | 0.5285 | No | ||
41 | CNOT2 | 12992 3332 453 3357 | 2748 | 0.222 | 0.5271 | No | ||
42 | CAMK2A | 2024 23541 1980 | 2823 | 0.210 | 0.5266 | No | ||
43 | SHMT1 | 5431 | 2871 | 0.203 | 0.5275 | No | ||
44 | BSCL2 | 23940 | 3015 | 0.185 | 0.5229 | No | ||
45 | AGER | 23276 1576 | 3017 | 0.185 | 0.5260 | No | ||
46 | THRAP1 | 20309 | 3054 | 0.180 | 0.5271 | No | ||
47 | P2RY2 | 17736 1279 | 3163 | 0.166 | 0.5240 | No | ||
48 | MAZ | 1327 17623 | 3332 | 0.147 | 0.5174 | No | ||
49 | CNTF | 3741 8761 3680 3736 | 3464 | 0.135 | 0.5126 | No | ||
50 | CASK | 24184 2618 2604 | 3500 | 0.131 | 0.5129 | No | ||
51 | VAPA | 22908 | 3566 | 0.124 | 0.5115 | No | ||
52 | KLF12 | 4960 2637 21732 9228 | 3693 | 0.116 | 0.5066 | No | ||
53 | ANKRD17 | 13496 3474 8170 | 3837 | 0.106 | 0.5007 | No | ||
54 | XPO1 | 4172 | 3925 | 0.101 | 0.4977 | No | ||
55 | SESN2 | 15733 | 3933 | 0.100 | 0.4990 | No | ||
56 | HOXA11 | 17146 | 4065 | 0.092 | 0.4934 | No | ||
57 | ZSWIM2 | 14548 | 4163 | 0.088 | 0.4897 | No | ||
58 | SCN3B | 39 3117 6163 10646 | 4217 | 0.085 | 0.4882 | No | ||
59 | ETV4 | 20212 | 4291 | 0.081 | 0.4857 | No | ||
60 | NRGN | 19176 | 4433 | 0.076 | 0.4793 | No | ||
61 | FIGN | 14575 | 4512 | 0.073 | 0.4763 | No | ||
62 | HOXB3 | 20685 | 4586 | 0.071 | 0.4736 | No | ||
63 | UBE2R2 | 16240 | 4669 | 0.068 | 0.4703 | No | ||
64 | RFX3 | 9722 5377 3712 3762 | 4726 | 0.066 | 0.4683 | No | ||
65 | GNAS | 9025 2963 2752 | 4797 | 0.064 | 0.4656 | No | ||
66 | SORT1 | 15452 5475 9847 | 5058 | 0.057 | 0.4525 | No | ||
67 | SPAG9 | 1322 12904 7707 | 5171 | 0.054 | 0.4474 | No | ||
68 | GMPR2 | 2711 | 5453 | 0.047 | 0.4329 | No | ||
69 | CACNA1G | 1237 940 20292 | 5708 | 0.042 | 0.4199 | No | ||
70 | ORMDL2 | 19588 | 6047 | 0.036 | 0.4022 | No | ||
71 | STC1 | 21974 | 6375 | 0.031 | 0.3850 | No | ||
72 | NEUROD6 | 17138 | 6384 | 0.031 | 0.3851 | No | ||
73 | BHLHB5 | 15629 | 6433 | 0.030 | 0.3830 | No | ||
74 | RIMS1 | 8575 | 6438 | 0.030 | 0.3833 | No | ||
75 | HRH4 | 23618 | 6456 | 0.030 | 0.3829 | No | ||
76 | PRDM13 | 15933 | 6494 | 0.029 | 0.3814 | No | ||
77 | COL12A1 | 3143 19054 | 6499 | 0.029 | 0.3816 | No | ||
78 | WNT3 | 20635 | 6648 | 0.027 | 0.3741 | No | ||
79 | RPL4 | 7499 19411 | 6687 | 0.026 | 0.3724 | No | ||
80 | SLC6A20 | 18955 | 6820 | 0.024 | 0.3657 | No | ||
81 | PRDM16 | 12893 | 6899 | 0.023 | 0.3619 | No | ||
82 | ZNF462 | 6321 | 6925 | 0.023 | 0.3609 | No | ||
83 | GNG3 | 23752 | 7024 | 0.022 | 0.3560 | No | ||
84 | BDNF | 14926 2797 | 7063 | 0.021 | 0.3543 | No | ||
85 | CANX | 4474 | 7196 | 0.020 | 0.3475 | No | ||
86 | GOLGA7 | 12188 | 7373 | 0.018 | 0.3382 | No | ||
87 | CDH20 | 14168 6222 | 7829 | 0.012 | 0.3138 | No | ||
88 | RHOBTB3 | 7849 | 7964 | 0.011 | 0.3067 | No | ||
89 | ACCN1 | 20327 1194 | 8049 | 0.010 | 0.3023 | No | ||
90 | HMGA2 | 4857 9098 3341 3444 | 8117 | 0.009 | 0.2989 | No | ||
91 | SILV | 16130 | 8128 | 0.009 | 0.2985 | No | ||
92 | NRXN3 | 2153 5196 | 8299 | 0.007 | 0.2894 | No | ||
93 | MYOZ2 | 15174 | 8791 | 0.002 | 0.2628 | No | ||
94 | B3GALT2 | 6498 | 8807 | 0.002 | 0.2620 | No | ||
95 | LYN | 16281 | 8848 | 0.001 | 0.2599 | No | ||
96 | PLXNC1 | 7056 | 8873 | 0.001 | 0.2586 | No | ||
97 | ODF2 | 9501 5205 2862 2949 | 8921 | 0.001 | 0.2561 | No | ||
98 | GNAT1 | 3027 19000 | 9511 | -0.005 | 0.2242 | No | ||
99 | TNNI1 | 14116 | 9558 | -0.006 | 0.2218 | No | ||
100 | TRIM2 | 13485 8157 | 9588 | -0.006 | 0.2204 | No | ||
101 | NR3C2 | 18562 13798 | 9757 | -0.008 | 0.2114 | No | ||
102 | SPOCK2 | 13585 | 10217 | -0.012 | 0.1867 | No | ||
103 | WNT5A | 22066 5880 | 10273 | -0.013 | 0.1840 | No | ||
104 | FGF12 | 1723 22621 | 10779 | -0.018 | 0.1569 | No | ||
105 | NMUR1 | 13898 | 10980 | -0.021 | 0.1464 | No | ||
106 | HNRPF | 13607 | 10982 | -0.021 | 0.1467 | No | ||
107 | HCN1 | 21557 | 11004 | -0.021 | 0.1460 | No | ||
108 | NDUFC1 | 7287 12339 | 11560 | -0.028 | 0.1164 | No | ||
109 | OMG | 5209 | 11603 | -0.028 | 0.1146 | No | ||
110 | C4A | 4460 8670 9832 8669 | 11654 | -0.029 | 0.1124 | No | ||
111 | LEP | 17505 | 11702 | -0.030 | 0.1103 | No | ||
112 | USP5 | 17004 | 11813 | -0.031 | 0.1049 | No | ||
113 | CHGA | 21178 2151 | 12068 | -0.035 | 0.0917 | No | ||
114 | CACNB3 | 22373 8679 | 12341 | -0.039 | 0.0776 | No | ||
115 | FOXF2 | 21677 | 12438 | -0.041 | 0.0731 | No | ||
116 | RAPSN | 2879 14951 | 12522 | -0.042 | 0.0693 | No | ||
117 | RARG | 22113 | 12611 | -0.044 | 0.0653 | No | ||
118 | LHX6 | 9275 2914 | 13615 | -0.067 | 0.0121 | No | ||
119 | LTBP1 | 1536 1604 6503 1559 1564 1518 | 13647 | -0.068 | 0.0116 | No | ||
120 | CUGBP1 | 2805 8819 4576 2924 | 13682 | -0.069 | 0.0109 | No | ||
121 | TMEM27 | 24214 | 13808 | -0.074 | 0.0054 | No | ||
122 | PNOC | 21783 | 13942 | -0.079 | -0.0005 | No | ||
123 | MYO18B | 16434 | 14039 | -0.083 | -0.0043 | No | ||
124 | ESRRG | 6447 | 14264 | -0.092 | -0.0148 | No | ||
125 | MGLL | 17368 1145 | 14328 | -0.095 | -0.0166 | No | ||
126 | LNPEP | 6267 10760 10761 | 14433 | -0.100 | -0.0206 | No | ||
127 | MAMDC1 | 21054 6798 | 14448 | -0.101 | -0.0196 | No | ||
128 | FRAS1 | 16788 3589 | 14799 | -0.120 | -0.0366 | No | ||
129 | EHMT1 | 13401 14670 2756 8090 | 14963 | -0.133 | -0.0432 | No | ||
130 | NCOA5 | 14341 | 14977 | -0.134 | -0.0416 | No | ||
131 | GRK5 | 9036 23814 | 14995 | -0.135 | -0.0402 | No | ||
132 | UBE3A | 1209 1084 1830 | 15011 | -0.136 | -0.0387 | No | ||
133 | ABHD2 | 18208 12043 | 15030 | -0.138 | -0.0374 | No | ||
134 | YWHAE | 20776 | 15156 | -0.149 | -0.0416 | No | ||
135 | PPARGC1B | 9318 | 15209 | -0.154 | -0.0418 | No | ||
136 | RIN1 | 10349 | 15512 | -0.190 | -0.0550 | No | ||
137 | PCSK1N | 6624 | 15541 | -0.195 | -0.0532 | No | ||
138 | LAMA3 | 23620 2009 | 15614 | -0.205 | -0.0536 | No | ||
139 | LMNA | 4999 15290 1778 9280 | 15624 | -0.206 | -0.0506 | No | ||
140 | PIK3R3 | 5248 | 15646 | -0.210 | -0.0482 | No | ||
141 | PCDH9 | 21736 | 15662 | -0.211 | -0.0455 | No | ||
142 | PRICKLE1 | 8379 | 15752 | -0.225 | -0.0465 | No | ||
143 | GPHN | 6492 21232 | 15791 | -0.233 | -0.0446 | No | ||
144 | TAF5 | 23833 5934 3759 | 15805 | -0.235 | -0.0413 | No | ||
145 | SEMA7A | 19426 9803 | 16067 | -0.288 | -0.0506 | No | ||
146 | E4F1 | 8875 | 16151 | -0.306 | -0.0499 | No | ||
147 | ASB7 | 1789 3574 8597 4390 | 16217 | -0.323 | -0.0480 | No | ||
148 | ING3 | 17514 1019 | 16481 | -0.391 | -0.0556 | No | ||
149 | SFRS5 | 9808 2062 | 16570 | -0.419 | -0.0533 | No | ||
150 | NRF1 | 17499 | 16635 | -0.441 | -0.0493 | No | ||
151 | RDH11 | 21031 | 16680 | -0.459 | -0.0439 | No | ||
152 | CSTF1 | 12515 | 17410 | -0.809 | -0.0697 | No | ||
153 | VAV1 | 23173 | 17957 | -1.172 | -0.0795 | No | ||
154 | SSBP2 | 3171 7364 3252 | 18006 | -1.217 | -0.0615 | No | ||
155 | PDAP1 | 16294 | 18296 | -1.670 | -0.0490 | No | ||
156 | YWHAQ | 10369 | 18378 | -1.909 | -0.0211 | No | ||
157 | CCL5 | 20320 | 18406 | -2.006 | 0.0114 | No |