Dataset | Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB |
Phenotype | phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB |
Upregulated in class | LMproB |
GeneSet | V$HSF1_01 |
Enrichment Score (ES) | -0.48355818 |
Normalized Enrichment Score (NES) | -1.3506728 |
Nominal p-value | 0.012987013 |
FDR q-value | 0.86936796 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TNFRSF19 | 21799 3033 | 224 | 2.206 | 0.0147 | No | ||
2 | BCL6 | 22624 | 290 | 1.956 | 0.0350 | No | ||
3 | RAB6B | 11289 | 366 | 1.742 | 0.0522 | No | ||
4 | CYLD | 18532 | 405 | 1.659 | 0.0704 | No | ||
5 | RASGRP2 | 9693 | 441 | 1.604 | 0.0880 | No | ||
6 | PDE6D | 13897 3945 | 446 | 1.588 | 0.1071 | No | ||
7 | SPO11 | 2666 14717 | 452 | 1.580 | 0.1261 | No | ||
8 | MAPK14 | 23313 | 503 | 1.495 | 0.1416 | No | ||
9 | DNAJB1 | 18553 | 559 | 1.400 | 0.1557 | No | ||
10 | MBNL2 | 21932 | 702 | 1.192 | 0.1625 | No | ||
11 | ABCD1 | 24305 | 728 | 1.167 | 0.1754 | No | ||
12 | ZFX | 5984 | 1002 | 0.958 | 0.1723 | No | ||
13 | SUHW3 | 24160 | 1190 | 0.819 | 0.1721 | No | ||
14 | ATP6V1A | 8638 | 1248 | 0.780 | 0.1785 | No | ||
15 | IGFBP5 | 4899 | 1322 | 0.728 | 0.1834 | No | ||
16 | SREBF2 | 5509 | 1395 | 0.690 | 0.1879 | No | ||
17 | EHD1 | 23791 | 1610 | 0.575 | 0.1833 | No | ||
18 | DMD | 24295 2647 | 1652 | 0.559 | 0.1879 | No | ||
19 | FHL1 | 24334 | 1679 | 0.547 | 0.1931 | No | ||
20 | PIP5K1A | 23708 | 1874 | 0.470 | 0.1883 | No | ||
21 | CCM2 | 20950 | 1908 | 0.455 | 0.1921 | No | ||
22 | CREM | 2005 1965 23496 1951 | 2027 | 0.404 | 0.1906 | No | ||
23 | LHFPL2 | 21584 | 2064 | 0.392 | 0.1935 | No | ||
24 | NR2F1 | 7015 21401 | 2232 | 0.345 | 0.1886 | No | ||
25 | BCL9 | 15232 | 2409 | 0.297 | 0.1827 | No | ||
26 | MRPS6 | 8656 | 2731 | 0.225 | 0.1680 | No | ||
27 | ADCY6 | 22139 2283 8551 | 2802 | 0.213 | 0.1668 | No | ||
28 | LENEP | 12181 | 3040 | 0.181 | 0.1562 | No | ||
29 | FSTL3 | 19961 | 3077 | 0.176 | 0.1564 | No | ||
30 | PERQ1 | 7168 | 3258 | 0.155 | 0.1485 | No | ||
31 | HIPK1 | 4851 | 3414 | 0.139 | 0.1418 | No | ||
32 | ADAMTS2 | 5706 20899 1356 | 3451 | 0.136 | 0.1415 | No | ||
33 | CNTF | 3741 8761 3680 3736 | 3464 | 0.135 | 0.1425 | No | ||
34 | LAP3 | 12442 | 3704 | 0.115 | 0.1309 | No | ||
35 | ISYNA1 | 12961 | 3715 | 0.114 | 0.1318 | No | ||
36 | MOBP | 5112 | 3860 | 0.104 | 0.1252 | No | ||
37 | FOXB1 | 12254 19069 | 3967 | 0.098 | 0.1207 | No | ||
38 | GPR17 | 399 | 4055 | 0.093 | 0.1171 | No | ||
39 | OTP | 21582 | 4066 | 0.092 | 0.1177 | No | ||
40 | RNF5 | 63 | 4333 | 0.080 | 0.1042 | No | ||
41 | BNC2 | 15850 | 4563 | 0.072 | 0.0926 | No | ||
42 | TRERF1 | 1546 23213 | 4568 | 0.071 | 0.0933 | No | ||
43 | BMPR2 | 14241 4081 | 4800 | 0.063 | 0.0815 | No | ||
44 | RPH3AL | 11725 | 4927 | 0.060 | 0.0754 | No | ||
45 | ITGA8 | 14685 | 5208 | 0.053 | 0.0609 | No | ||
46 | GAD2 | 15108 | 5245 | 0.052 | 0.0596 | No | ||
47 | PLEKHB1 | 21729 2755 4059 17738 | 5267 | 0.052 | 0.0591 | No | ||
48 | GRM1 | 19822 | 5315 | 0.051 | 0.0572 | No | ||
49 | CBX3 | 8705 4484 | 5334 | 0.050 | 0.0568 | No | ||
50 | DNAJA1 | 4878 16242 2345 | 5340 | 0.050 | 0.0571 | No | ||
51 | FOXD2 | 15802 | 5366 | 0.050 | 0.0564 | No | ||
52 | LUZP1 | 6533 11257 2503 | 5372 | 0.049 | 0.0567 | No | ||
53 | WRN | 5882 10315 | 5399 | 0.049 | 0.0559 | No | ||
54 | DAZL | 22944 | 5463 | 0.047 | 0.0531 | No | ||
55 | PHF6 | 2648 24340 | 5571 | 0.045 | 0.0478 | No | ||
56 | RORB | 10356 | 5668 | 0.043 | 0.0431 | No | ||
57 | ABCC5 | 22639 351 | 5705 | 0.043 | 0.0417 | No | ||
58 | OTX2 | 9519 | 5718 | 0.042 | 0.0416 | No | ||
59 | NFATC3 | 5169 | 5784 | 0.041 | 0.0385 | No | ||
60 | JAM3 | 8197 | 5839 | 0.040 | 0.0361 | No | ||
61 | SLC24A4 | 6223 | 6146 | 0.035 | 0.0199 | No | ||
62 | PTGIS | 9653 | 6168 | 0.034 | 0.0192 | No | ||
63 | STC1 | 21974 | 6375 | 0.031 | 0.0084 | No | ||
64 | NFATC4 | 22002 | 6517 | 0.028 | 0.0011 | No | ||
65 | POU4F3 | 9604 | 6558 | 0.028 | -0.0007 | No | ||
66 | TYR | 17763 | 7052 | 0.022 | -0.0272 | No | ||
67 | TRDN | 20062 | 7195 | 0.020 | -0.0347 | No | ||
68 | HS6ST3 | 21933 | 7379 | 0.018 | -0.0444 | No | ||
69 | GREB1 | 6490 2152 | 7482 | 0.017 | -0.0497 | No | ||
70 | OSR2 | 22492 | 7684 | 0.014 | -0.0604 | No | ||
71 | GLRA3 | 18617 | 7691 | 0.014 | -0.0606 | No | ||
72 | NEK6 | 15018 | 7735 | 0.014 | -0.0628 | No | ||
73 | CRISP1 | 22980 | 7904 | 0.012 | -0.0717 | No | ||
74 | MAP2K1IP1 | 12158 | 7925 | 0.011 | -0.0727 | No | ||
75 | CHML | 13741 | 8172 | 0.009 | -0.0859 | No | ||
76 | CLDN2 | 4527 | 8176 | 0.008 | -0.0860 | No | ||
77 | NRXN3 | 2153 5196 | 8299 | 0.007 | -0.0925 | No | ||
78 | ABHD3 | 23491 | 8317 | 0.007 | -0.0933 | No | ||
79 | NR4A3 | 9473 16212 5183 | 8349 | 0.006 | -0.0949 | No | ||
80 | STX12 | 4140 | 8850 | 0.001 | -0.1220 | No | ||
81 | PLXNC1 | 7056 | 8873 | 0.001 | -0.1232 | No | ||
82 | WDR12 | 13942 | 9095 | -0.001 | -0.1352 | No | ||
83 | FAP | 14577 | 9166 | -0.002 | -0.1390 | No | ||
84 | ADCY8 | 22281 | 9222 | -0.003 | -0.1419 | No | ||
85 | CACNA2D2 | 7154 | 9226 | -0.003 | -0.1420 | No | ||
86 | SMYD1 | 4452 | 9353 | -0.004 | -0.1488 | No | ||
87 | PTHLH | 16931 | 9355 | -0.004 | -0.1488 | No | ||
88 | IL2 | 15354 | 9362 | -0.004 | -0.1491 | No | ||
89 | RFX4 | 7721 3410 | 9495 | -0.005 | -0.1562 | No | ||
90 | DMRT1 | 23899 | 9677 | -0.007 | -0.1659 | No | ||
91 | ADAMTS9 | 17063 | 9699 | -0.007 | -0.1670 | No | ||
92 | CHST8 | 12754 | 9703 | -0.007 | -0.1671 | No | ||
93 | HSPB1 | 4879 | 9741 | -0.007 | -0.1690 | No | ||
94 | WNT8B | 23841 | 9798 | -0.008 | -0.1719 | No | ||
95 | ARHGAP6 | 24207 | 10039 | -0.010 | -0.1848 | No | ||
96 | HOXB8 | 9111 | 10175 | -0.012 | -0.1920 | No | ||
97 | RIMS2 | 4370 | 10510 | -0.015 | -0.2099 | No | ||
98 | SOCS5 | 1619 23141 | 10533 | -0.015 | -0.2109 | No | ||
99 | A2BP1 | 11212 1652 1689 | 10578 | -0.016 | -0.2131 | No | ||
100 | TREX1 | 10219 3111 | 11042 | -0.021 | -0.2380 | No | ||
101 | PPP2R5C | 6522 2147 | 11139 | -0.023 | -0.2429 | No | ||
102 | SIX4 | 5445 | 11454 | -0.027 | -0.2596 | No | ||
103 | NNAT | 2764 5180 | 11612 | -0.029 | -0.2678 | No | ||
104 | BCAP31 | 24134 | 11668 | -0.029 | -0.2704 | No | ||
105 | PLXDC2 | 15114 | 11817 | -0.031 | -0.2780 | No | ||
106 | PAK3 | 9528 | 11842 | -0.032 | -0.2790 | No | ||
107 | NR2C2 | 10216 | 11864 | -0.032 | -0.2797 | No | ||
108 | PAK1IP1 | 21660 | 12078 | -0.035 | -0.2908 | No | ||
109 | DMRTA1 | 16177 | 12351 | -0.039 | -0.3051 | No | ||
110 | PPT2 | 1617 12034 | 12423 | -0.041 | -0.3085 | No | ||
111 | MYOCD | 1382 20406 1401 | 12424 | -0.041 | -0.3080 | No | ||
112 | E2F3 | 21500 8874 | 12512 | -0.042 | -0.3122 | No | ||
113 | HCN4 | 9080 | 12547 | -0.042 | -0.3135 | No | ||
114 | ALS2CR8 | 10793 | 12763 | -0.046 | -0.3246 | No | ||
115 | NOL4 | 2028 11432 | 12911 | -0.049 | -0.3320 | No | ||
116 | SCG2 | 5410 14425 | 12960 | -0.050 | -0.3340 | No | ||
117 | PURG | 7943 | 13125 | -0.054 | -0.3422 | No | ||
118 | H2AFZ | 6957 | 13142 | -0.054 | -0.3424 | No | ||
119 | DMRTB1 | 15813 | 13214 | -0.056 | -0.3456 | No | ||
120 | KCNQ1 | 18001 4948 | 13225 | -0.056 | -0.3455 | No | ||
121 | TRIB1 | 22467 | 13236 | -0.056 | -0.3453 | No | ||
122 | RTN1 | 4177 2099 | 13253 | -0.057 | -0.3455 | No | ||
123 | PCDH10 | 5227 9534 1893 | 13431 | -0.061 | -0.3543 | No | ||
124 | FLNC | 4302 8510 | 13470 | -0.063 | -0.3556 | No | ||
125 | SRP54 | 6282 | 13473 | -0.063 | -0.3550 | No | ||
126 | SMAD1 | 18831 922 | 13805 | -0.074 | -0.3720 | No | ||
127 | ANKRD22 | 6970 | 14005 | -0.082 | -0.3818 | No | ||
128 | TPM2 | 2367 2437 | 14038 | -0.083 | -0.3825 | No | ||
129 | GRIK1 | 22550 1741 | 14277 | -0.092 | -0.3943 | No | ||
130 | ARL6IP2 | 1496 7090 12093 | 14416 | -0.099 | -0.4006 | No | ||
131 | GAD1 | 14993 2690 | 14588 | -0.108 | -0.4086 | No | ||
132 | HNRPA2B1 | 1187 7001 7000 1040 | 14665 | -0.112 | -0.4113 | No | ||
133 | KNTC1 | 16705 | 14677 | -0.113 | -0.4105 | No | ||
134 | ATP1B2 | 20390 | 14701 | -0.114 | -0.4104 | No | ||
135 | HIVEP2 | 9091 | 14813 | -0.121 | -0.4149 | No | ||
136 | ELAVL4 | 15805 4889 9137 | 14877 | -0.126 | -0.4168 | No | ||
137 | ACTN2 | 21545 | 15268 | -0.160 | -0.4360 | No | ||
138 | PIP5K3 | 14234 | 15311 | -0.165 | -0.4363 | No | ||
139 | AGPAT1 | 23275 | 15401 | -0.176 | -0.4390 | No | ||
140 | CCNG1 | 4492 1236 1390 | 15406 | -0.176 | -0.4371 | No | ||
141 | GATA3 | 9004 | 15431 | -0.179 | -0.4362 | No | ||
142 | ANKRD25 | 6161 | 15441 | -0.180 | -0.4345 | No | ||
143 | OPRD1 | 15737 | 15569 | -0.199 | -0.4389 | No | ||
144 | PACSIN3 | 14948 8149 2776 2665 | 15685 | -0.215 | -0.4426 | No | ||
145 | YWHAG | 16339 | 16043 | -0.282 | -0.4585 | No | ||
146 | RBPMS | 5369 | 16099 | -0.293 | -0.4579 | No | ||
147 | EGR3 | 4656 | 16111 | -0.298 | -0.4549 | No | ||
148 | TLK1 | 14563 | 16233 | -0.326 | -0.4574 | No | ||
149 | EOMES | 4669 | 16242 | -0.329 | -0.4539 | No | ||
150 | DNAJB5 | 16236 | 16448 | -0.385 | -0.4603 | No | ||
151 | GSN | 2784 | 16488 | -0.392 | -0.4576 | No | ||
152 | NT5C3 | 17136 | 16967 | -0.577 | -0.4765 | Yes | ||
153 | DBI | 13853 | 16994 | -0.585 | -0.4708 | Yes | ||
154 | SERPINH1 | 8703 | 17002 | -0.588 | -0.4640 | Yes | ||
155 | CHD1 | 23377 | 17027 | -0.600 | -0.4580 | Yes | ||
156 | PIM1 | 23308 | 17127 | -0.645 | -0.4555 | Yes | ||
157 | ASAH2 | 23699 | 17176 | -0.667 | -0.4500 | Yes | ||
158 | UBE2E2 | 21914 | 17375 | -0.783 | -0.4512 | Yes | ||
159 | PRKAG1 | 22135 | 17428 | -0.824 | -0.4440 | Yes | ||
160 | MAP3K7IP2 | 19827 | 17482 | -0.856 | -0.4364 | Yes | ||
161 | AAMP | 10406 | 17572 | -0.902 | -0.4303 | Yes | ||
162 | MORF4L2 | 12118 | 17612 | -0.932 | -0.4210 | Yes | ||
163 | PLXNA2 | 5269 | 17929 | -1.150 | -0.4241 | Yes | ||
164 | HSPD1 | 4078 9129 | 17940 | -1.159 | -0.4106 | Yes | ||
165 | FOS | 21202 | 17967 | -1.183 | -0.3976 | Yes | ||
166 | CHORDC1 | 12430 | 18061 | -1.286 | -0.3869 | Yes | ||
167 | HSPB8 | 16405 | 18141 | -1.413 | -0.3740 | Yes | ||
168 | EPHA2 | 16006 | 18224 | -1.564 | -0.3594 | Yes | ||
169 | EIF5 | 5736 | 18257 | -1.593 | -0.3417 | Yes | ||
170 | HSPA8 | 9124 3072 4871 | 18273 | -1.625 | -0.3227 | Yes | ||
171 | DUSP1 | 23061 | 18279 | -1.643 | -0.3030 | Yes | ||
172 | JUN | 15832 | 18330 | -1.748 | -0.2844 | Yes | ||
173 | ELOVL5 | 19373 | 18418 | -2.079 | -0.2638 | Yes | ||
174 | ST13 | 12865 | 18484 | -2.298 | -0.2393 | Yes | ||
175 | FKBP4 | 4726 | 18514 | -2.486 | -0.2106 | Yes | ||
176 | CCT3 | 8709 | 18555 | -2.896 | -0.1775 | Yes | ||
177 | HSPH1 | 16282 | 18572 | -3.143 | -0.1400 | Yes | ||
178 | CISH | 8743 | 18602 | -4.700 | -0.0844 | Yes | ||
179 | SOCS2 | 5694 | 18613 | -6.981 | 0.0002 | Yes |