Dataset | Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB |
Phenotype | phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB |
Upregulated in class | LMproB |
GeneSet | V$E2F_Q6 |
Enrichment Score (ES) | -0.48679414 |
Normalized Enrichment Score (NES) | -1.32737 |
Nominal p-value | 0.02739726 |
FDR q-value | 0.8365867 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | HIRA | 4852 9090 | 363 | 1.744 | 0.0092 | No | ||
2 | IL4I1 | 8971 | 577 | 1.366 | 0.0203 | No | ||
3 | ZCCHC8 | 3570 7696 | 659 | 1.246 | 0.0366 | No | ||
4 | TBX6 | 1993 18075 | 851 | 1.053 | 0.0437 | No | ||
5 | MCM7 | 9372 3568 | 909 | 1.013 | 0.0574 | No | ||
6 | SFRS1 | 8492 | 1170 | 0.831 | 0.0570 | No | ||
7 | CDC25A | 8721 | 1206 | 0.810 | 0.0686 | No | ||
8 | HIST1H2BK | 11423 | 1268 | 0.763 | 0.0779 | No | ||
9 | PPP1CC | 9609 5283 | 1296 | 0.747 | 0.0888 | No | ||
10 | MCM4 | 22655 1708 | 1343 | 0.719 | 0.0982 | No | ||
11 | MXD3 | 21455 | 1495 | 0.627 | 0.1004 | No | ||
12 | FANCD2 | 17326 464 | 1511 | 0.622 | 0.1099 | No | ||
13 | USP52 | 3397 19841 | 1586 | 0.586 | 0.1156 | No | ||
14 | DMD | 24295 2647 | 1652 | 0.559 | 0.1213 | No | ||
15 | SFRS2 | 9807 20136 | 1700 | 0.535 | 0.1277 | No | ||
16 | MRPL40 | 22641 | 1944 | 0.437 | 0.1217 | No | ||
17 | EED | 17759 | 2004 | 0.415 | 0.1254 | No | ||
18 | RBL1 | 14373 | 2062 | 0.393 | 0.1288 | No | ||
19 | MCM3 | 13991 | 2298 | 0.325 | 0.1215 | No | ||
20 | ATF5 | 17843 | 2309 | 0.322 | 0.1263 | No | ||
21 | SFRS7 | 22889 | 2312 | 0.322 | 0.1315 | No | ||
22 | HMGN2 | 9095 | 2501 | 0.274 | 0.1259 | No | ||
23 | UFD1L | 22825 | 2798 | 0.214 | 0.1134 | No | ||
24 | PHF13 | 15659 | 2810 | 0.211 | 0.1163 | No | ||
25 | BRMS1L | 21268 | 2916 | 0.197 | 0.1139 | No | ||
26 | RQCD1 | 12205 | 2948 | 0.193 | 0.1154 | No | ||
27 | STMN1 | 9261 | 3010 | 0.186 | 0.1152 | No | ||
28 | CTCF | 18490 | 3227 | 0.158 | 0.1061 | No | ||
29 | CORT | 15669 2539 | 3251 | 0.156 | 0.1074 | No | ||
30 | SOAT1 | 13797 | 3278 | 0.153 | 0.1086 | No | ||
31 | MAZ | 1327 17623 | 3332 | 0.147 | 0.1081 | No | ||
32 | DDB2 | 2721 2878 14525 2661 | 3439 | 0.137 | 0.1047 | No | ||
33 | ADAMTS2 | 5706 20899 1356 | 3451 | 0.136 | 0.1063 | No | ||
34 | ILF3 | 3110 3030 9176 | 3457 | 0.136 | 0.1083 | No | ||
35 | STAG2 | 5521 | 3550 | 0.126 | 0.1054 | No | ||
36 | SLC6A4 | 20770 | 3646 | 0.119 | 0.1022 | No | ||
37 | ALDH6A1 | 21025 | 3930 | 0.100 | 0.0886 | No | ||
38 | RHD | 16042 | 3949 | 0.099 | 0.0892 | No | ||
39 | CDC45L | 22642 1752 | 4042 | 0.093 | 0.0858 | No | ||
40 | RAD51 | 2897 14903 | 4111 | 0.090 | 0.0836 | No | ||
41 | STAG1 | 5520 9905 2987 | 4115 | 0.090 | 0.0849 | No | ||
42 | DNMT1 | 19217 | 4193 | 0.086 | 0.0822 | No | ||
43 | PRPF4B | 3208 5295 | 4549 | 0.072 | 0.0641 | No | ||
44 | ZBTB4 | 13267 | 4666 | 0.068 | 0.0590 | No | ||
45 | DNAJC9 | 21912 | 4736 | 0.066 | 0.0563 | No | ||
46 | YBX2 | 20818 | 4833 | 0.063 | 0.0522 | No | ||
47 | FBXO5 | 19830 | 5085 | 0.056 | 0.0395 | No | ||
48 | IPO7 | 6130 | 5090 | 0.056 | 0.0402 | No | ||
49 | SMAD6 | 19083 | 5682 | 0.043 | 0.0089 | No | ||
50 | HCN3 | 4843 1763 | 5998 | 0.037 | -0.0075 | No | ||
51 | HNRPR | 13196 7909 2500 | 6305 | 0.032 | -0.0235 | No | ||
52 | PODN | 15811 | 6440 | 0.030 | -0.0303 | No | ||
53 | GRIA4 | 19249 | 6635 | 0.027 | -0.0404 | No | ||
54 | NUP153 | 21474 | 6702 | 0.026 | -0.0435 | No | ||
55 | NRP2 | 5194 9486 5195 | 6753 | 0.025 | -0.0458 | No | ||
56 | ERBB2IP | 3232 12234 | 6803 | 0.025 | -0.0481 | No | ||
57 | HNRPD | 8645 | 7158 | 0.020 | -0.0669 | No | ||
58 | HS6ST3 | 21933 | 7379 | 0.018 | -0.0785 | No | ||
59 | JPH1 | 13994 | 7489 | 0.016 | -0.0841 | No | ||
60 | ARID4A | 2080 6215 | 8166 | 0.009 | -0.1206 | No | ||
61 | KCND2 | 4941 17515 | 8517 | 0.005 | -0.1395 | No | ||
62 | RPS6KA5 | 2076 21005 | 8609 | 0.004 | -0.1444 | No | ||
63 | MCM8 | 14834 | 8614 | 0.004 | -0.1445 | No | ||
64 | EZH2 | 1092 17163 | 8828 | 0.001 | -0.1560 | No | ||
65 | ATAD2 | 2268 2256 | 8840 | 0.001 | -0.1566 | No | ||
66 | PAQR4 | 23105 | 9093 | -0.001 | -0.1702 | No | ||
67 | FMO4 | 13786 | 9259 | -0.003 | -0.1791 | No | ||
68 | TREX2 | 24137 | 9295 | -0.003 | -0.1810 | No | ||
69 | POLE2 | 21053 | 9793 | -0.008 | -0.2077 | No | ||
70 | CASP8AP2 | 16253 | 9852 | -0.008 | -0.2107 | No | ||
71 | ARHGAP6 | 24207 | 10039 | -0.010 | -0.2206 | No | ||
72 | PAX6 | 5223 | 10074 | -0.011 | -0.2223 | No | ||
73 | SEMA6A | 23439 9802 | 10420 | -0.014 | -0.2408 | No | ||
74 | SP3 | 5483 | 10452 | -0.015 | -0.2422 | No | ||
75 | CBX5 | 22108 4485 | 10531 | -0.015 | -0.2462 | No | ||
76 | PRKDC | 9617 22847 | 10538 | -0.016 | -0.2462 | No | ||
77 | RANBP1 | 9692 5357 | 10703 | -0.018 | -0.2548 | No | ||
78 | PCSK1 | 21600 | 10705 | -0.018 | -0.2546 | No | ||
79 | GABRB3 | 4747 | 10801 | -0.019 | -0.2594 | No | ||
80 | E2F7 | 19884 | 11351 | -0.025 | -0.2887 | No | ||
81 | INSM1 | 14815 | 11368 | -0.026 | -0.2892 | No | ||
82 | HNRPA1 | 9103 4860 | 11962 | -0.033 | -0.3207 | No | ||
83 | STK35 | 14851 | 11969 | -0.033 | -0.3205 | No | ||
84 | E2F3 | 21500 8874 | 12512 | -0.042 | -0.3492 | No | ||
85 | CDC6 | 6221 6220 | 12726 | -0.046 | -0.3599 | No | ||
86 | SYNGR4 | 17825 | 12882 | -0.048 | -0.3675 | No | ||
87 | NELL2 | 12006 7020 22151 | 12894 | -0.049 | -0.3673 | No | ||
88 | KCNA6 | 664 16990 665 4938 | 13086 | -0.053 | -0.3768 | No | ||
89 | H2AFZ | 6957 | 13142 | -0.054 | -0.3789 | No | ||
90 | WEE1 | 18127 | 13195 | -0.055 | -0.3808 | No | ||
91 | EPHB1 | 19024 | 13254 | -0.057 | -0.3830 | No | ||
92 | UXT | 5837 10267 | 13560 | -0.066 | -0.3984 | No | ||
93 | RRM2 | 5401 5400 | 13608 | -0.067 | -0.3999 | No | ||
94 | PVRL1 | 3006 19482 12211 7192 | 13915 | -0.078 | -0.4151 | No | ||
95 | DNAJC11 | 2486 6068 | 13988 | -0.081 | -0.4177 | No | ||
96 | MCM6 | 4000 13845 4119 | 14373 | -0.097 | -0.4369 | No | ||
97 | SLCO3A1 | 17796 4237 8430 | 14526 | -0.105 | -0.4434 | No | ||
98 | CLSPN | 16079 11256 6530 | 14635 | -0.111 | -0.4474 | No | ||
99 | TYRO3 | 5811 | 14772 | -0.118 | -0.4528 | No | ||
100 | HNRPUL1 | 6118 17923 1608 10577 1345 | 14839 | -0.123 | -0.4543 | No | ||
101 | TOPBP1 | 10659 | 14925 | -0.130 | -0.4568 | No | ||
102 | SEMA5A | 22496 5423 | 15094 | -0.143 | -0.4635 | No | ||
103 | SLC38A1 | 22148 | 15129 | -0.147 | -0.4629 | No | ||
104 | E2F1 | 14384 | 15142 | -0.148 | -0.4611 | No | ||
105 | RAB11B | 9676 | 15199 | -0.153 | -0.4616 | No | ||
106 | EFNA5 | 4655 8884 | 15321 | -0.166 | -0.4654 | No | ||
107 | PHF15 | 20467 8050 | 15540 | -0.195 | -0.4740 | No | ||
108 | AP4M1 | 3499 16656 | 15584 | -0.201 | -0.4730 | No | ||
109 | HOXC10 | 22342 | 15638 | -0.209 | -0.4724 | No | ||
110 | POLR2A | 5394 | 15739 | -0.224 | -0.4741 | No | ||
111 | ASXL2 | 7957 | 15838 | -0.241 | -0.4754 | No | ||
112 | PHC1 | 17013 | 15853 | -0.244 | -0.4722 | No | ||
113 | CCNT1 | 22140 11607 | 15926 | -0.256 | -0.4718 | No | ||
114 | PHF5A | 22194 | 15960 | -0.263 | -0.4692 | No | ||
115 | POLD3 | 17742 | 16285 | -0.340 | -0.4812 | Yes | ||
116 | GMNN | 21513 | 16323 | -0.351 | -0.4774 | Yes | ||
117 | SNRPD1 | 23622 | 16386 | -0.368 | -0.4746 | Yes | ||
118 | NUP62 | 9497 | 16415 | -0.377 | -0.4699 | Yes | ||
119 | HIST1H4A | 11590 | 16440 | -0.384 | -0.4648 | Yes | ||
120 | ING3 | 17514 1019 | 16481 | -0.391 | -0.4605 | Yes | ||
121 | MCM2 | 17074 | 16584 | -0.423 | -0.4590 | Yes | ||
122 | ACBD6 | 14089 | 16627 | -0.439 | -0.4540 | Yes | ||
123 | HIST1H2AH | 11414 | 16630 | -0.439 | -0.4469 | Yes | ||
124 | POLE4 | 12441 | 16649 | -0.448 | -0.4404 | Yes | ||
125 | GPRC5B | 17662 | 16662 | -0.452 | -0.4336 | Yes | ||
126 | MYH10 | 8077 | 16724 | -0.474 | -0.4291 | Yes | ||
127 | AK2 | 8563 2479 16073 | 16848 | -0.535 | -0.4269 | Yes | ||
128 | PPM1D | 20721 | 17001 | -0.588 | -0.4254 | Yes | ||
129 | USP37 | 13923 | 17077 | -0.623 | -0.4191 | Yes | ||
130 | PIM1 | 23308 | 17127 | -0.645 | -0.4111 | Yes | ||
131 | FHOD1 | 18772 | 17130 | -0.646 | -0.4005 | Yes | ||
132 | ACO2 | 8527 | 17408 | -0.809 | -0.4021 | Yes | ||
133 | POLA2 | 23988 | 17453 | -0.841 | -0.3905 | Yes | ||
134 | PPP1R8 | 15730 | 17511 | -0.869 | -0.3792 | Yes | ||
135 | CDT1 | 18437 | 17522 | -0.874 | -0.3653 | Yes | ||
136 | CDCA7 | 12437 | 17611 | -0.932 | -0.3546 | Yes | ||
137 | NOLC1 | 7704 | 17688 | -0.989 | -0.3424 | Yes | ||
138 | HTF9C | 4886 1678 | 17690 | -0.992 | -0.3260 | Yes | ||
139 | KPNB1 | 20274 | 17794 | -1.043 | -0.3143 | Yes | ||
140 | NCL | 5153 13899 | 17866 | -1.091 | -0.3001 | Yes | ||
141 | DCK | 16808 | 17883 | -1.106 | -0.2826 | Yes | ||
142 | POLD1 | 17847 | 17890 | -1.117 | -0.2645 | Yes | ||
143 | GSPT1 | 9046 | 17911 | -1.132 | -0.2468 | Yes | ||
144 | PCNA | 9535 | 18149 | -1.424 | -0.2361 | Yes | ||
145 | SUMO1 | 5826 3943 10247 | 18207 | -1.537 | -0.2137 | Yes | ||
146 | UGCGL1 | 6721 | 18270 | -1.619 | -0.1902 | Yes | ||
147 | TMPO | 5778 | 18301 | -1.680 | -0.1640 | Yes | ||
148 | UNG | 10257 16744 | 18367 | -1.876 | -0.1365 | Yes | ||
149 | PRPS1 | 24233 | 18424 | -2.091 | -0.1049 | Yes | ||
150 | MSH2 | 23138 | 18433 | -2.139 | -0.0699 | Yes | ||
151 | SFRS10 | 9818 1722 5441 | 18461 | -2.231 | -0.0344 | Yes | ||
152 | NASP | 2383 2387 6955 | 18526 | -2.581 | 0.0049 | Yes |