Dataset | Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB |
Phenotype | phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB |
Upregulated in class | LMproB |
GeneSet | V$E2F1_Q6 |
Enrichment Score (ES) | -0.49340358 |
Normalized Enrichment Score (NES) | -1.3548167 |
Nominal p-value | 0.006637168 |
FDR q-value | 0.92370546 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | KLF5 | 4456 | 328 | 1.857 | 0.0082 | No | ||
2 | HIRA | 4852 9090 | 363 | 1.744 | 0.0307 | No | ||
3 | HMGA1 | 23323 | 554 | 1.407 | 0.0400 | No | ||
4 | IL4I1 | 8971 | 577 | 1.366 | 0.0579 | No | ||
5 | ZCCHC8 | 3570 7696 | 659 | 1.246 | 0.0709 | No | ||
6 | TBX6 | 1993 18075 | 851 | 1.053 | 0.0752 | No | ||
7 | MCM7 | 9372 3568 | 909 | 1.013 | 0.0863 | No | ||
8 | SFRS1 | 8492 | 1170 | 0.831 | 0.0838 | No | ||
9 | CDC25A | 8721 | 1206 | 0.810 | 0.0932 | No | ||
10 | HIST1H2BK | 11423 | 1268 | 0.763 | 0.1006 | No | ||
11 | FLI1 | 4729 | 1305 | 0.736 | 0.1089 | No | ||
12 | MCM4 | 22655 1708 | 1343 | 0.719 | 0.1169 | No | ||
13 | MXD3 | 21455 | 1495 | 0.627 | 0.1175 | No | ||
14 | FANCD2 | 17326 464 | 1511 | 0.622 | 0.1254 | No | ||
15 | USP52 | 3397 19841 | 1586 | 0.586 | 0.1295 | No | ||
16 | SSBP3 | 2439 7814 2431 | 1597 | 0.581 | 0.1371 | No | ||
17 | DMD | 24295 2647 | 1652 | 0.559 | 0.1420 | No | ||
18 | FANCC | 4712 | 1768 | 0.510 | 0.1429 | No | ||
19 | MRPL40 | 22641 | 1944 | 0.437 | 0.1395 | No | ||
20 | EED | 17759 | 2004 | 0.415 | 0.1421 | No | ||
21 | MAP3K7 | 16255 | 2033 | 0.403 | 0.1462 | No | ||
22 | RBL1 | 14373 | 2062 | 0.393 | 0.1502 | No | ||
23 | MCM3 | 13991 | 2298 | 0.325 | 0.1420 | No | ||
24 | ATF5 | 17843 | 2309 | 0.322 | 0.1459 | No | ||
25 | SFRS7 | 22889 | 2312 | 0.322 | 0.1503 | No | ||
26 | MSH5 | 23010 1599 | 2357 | 0.309 | 0.1523 | No | ||
27 | ATE1 | 388 17602 | 2538 | 0.266 | 0.1462 | No | ||
28 | PHF13 | 15659 | 2810 | 0.211 | 0.1345 | No | ||
29 | BRMS1L | 21268 | 2916 | 0.197 | 0.1316 | No | ||
30 | RQCD1 | 12205 | 2948 | 0.193 | 0.1326 | No | ||
31 | STMN1 | 9261 | 3010 | 0.186 | 0.1319 | No | ||
32 | CTCF | 18490 | 3227 | 0.158 | 0.1224 | No | ||
33 | CORT | 15669 2539 | 3251 | 0.156 | 0.1233 | No | ||
34 | SOAT1 | 13797 | 3278 | 0.153 | 0.1240 | No | ||
35 | MAZ | 1327 17623 | 3332 | 0.147 | 0.1232 | No | ||
36 | FANCG | 15904 | 3442 | 0.137 | 0.1192 | No | ||
37 | ADAMTS2 | 5706 20899 1356 | 3451 | 0.136 | 0.1207 | No | ||
38 | ILF3 | 3110 3030 9176 | 3457 | 0.136 | 0.1223 | No | ||
39 | STAG2 | 5521 | 3550 | 0.126 | 0.1191 | No | ||
40 | ALDH6A1 | 21025 | 3930 | 0.100 | 0.1000 | No | ||
41 | STAG1 | 5520 9905 2987 | 4115 | 0.090 | 0.0913 | No | ||
42 | DNMT1 | 19217 | 4193 | 0.086 | 0.0883 | No | ||
43 | PRPF4B | 3208 5295 | 4549 | 0.072 | 0.0701 | No | ||
44 | ZBTB4 | 13267 | 4666 | 0.068 | 0.0647 | No | ||
45 | DNAJC9 | 21912 | 4736 | 0.066 | 0.0619 | No | ||
46 | YBX2 | 20818 | 4833 | 0.063 | 0.0576 | No | ||
47 | KCNS2 | 4949 2232 | 5001 | 0.058 | 0.0493 | No | ||
48 | FBXO5 | 19830 | 5085 | 0.056 | 0.0456 | No | ||
49 | IPO7 | 6130 | 5090 | 0.056 | 0.0462 | No | ||
50 | CBX3 | 8705 4484 | 5334 | 0.050 | 0.0337 | No | ||
51 | SMAD6 | 19083 | 5682 | 0.043 | 0.0156 | No | ||
52 | CACNA1G | 1237 940 20292 | 5708 | 0.042 | 0.0148 | No | ||
53 | HCN3 | 4843 1763 | 5998 | 0.037 | -0.0003 | No | ||
54 | GATA1 | 24196 | 6059 | 0.036 | -0.0031 | No | ||
55 | SALL1 | 18796 12207 | 6090 | 0.036 | -0.0042 | No | ||
56 | HNRPR | 13196 7909 2500 | 6305 | 0.032 | -0.0154 | No | ||
57 | PODN | 15811 | 6440 | 0.030 | -0.0222 | No | ||
58 | GRIA4 | 19249 | 6635 | 0.027 | -0.0323 | No | ||
59 | ERBB2IP | 3232 12234 | 6803 | 0.025 | -0.0410 | No | ||
60 | SYNCRIP | 3078 3035 3107 | 6830 | 0.024 | -0.0421 | No | ||
61 | HNRPD | 8645 | 7158 | 0.020 | -0.0595 | No | ||
62 | HS6ST3 | 21933 | 7379 | 0.018 | -0.0712 | No | ||
63 | ARID4A | 2080 6215 | 8166 | 0.009 | -0.1137 | No | ||
64 | RPS6KA5 | 2076 21005 | 8609 | 0.004 | -0.1376 | No | ||
65 | MCM8 | 14834 | 8614 | 0.004 | -0.1377 | No | ||
66 | EZH2 | 1092 17163 | 8828 | 0.001 | -0.1492 | No | ||
67 | ATAD2 | 2268 2256 | 8840 | 0.001 | -0.1498 | No | ||
68 | PAQR4 | 23105 | 9093 | -0.001 | -0.1635 | No | ||
69 | ORC1L | 327 16144 | 9197 | -0.002 | -0.1690 | No | ||
70 | FMO4 | 13786 | 9259 | -0.003 | -0.1723 | No | ||
71 | POLE2 | 21053 | 9793 | -0.008 | -0.2010 | No | ||
72 | CASP8AP2 | 16253 | 9852 | -0.008 | -0.2041 | No | ||
73 | NRK | 6559 | 9910 | -0.009 | -0.2070 | No | ||
74 | ARHGAP6 | 24207 | 10039 | -0.010 | -0.2138 | No | ||
75 | PAX6 | 5223 | 10074 | -0.011 | -0.2155 | No | ||
76 | MYC | 22465 9435 | 10272 | -0.013 | -0.2260 | No | ||
77 | SLC9A7 | 24177 | 10346 | -0.013 | -0.2298 | No | ||
78 | SEMA6A | 23439 9802 | 10420 | -0.014 | -0.2335 | No | ||
79 | SP3 | 5483 | 10452 | -0.015 | -0.2350 | No | ||
80 | PRKDC | 9617 22847 | 10538 | -0.016 | -0.2394 | No | ||
81 | RANBP1 | 9692 5357 | 10703 | -0.018 | -0.2480 | No | ||
82 | PCSK1 | 21600 | 10705 | -0.018 | -0.2478 | No | ||
83 | GABRB3 | 4747 | 10801 | -0.019 | -0.2527 | No | ||
84 | E2F7 | 19884 | 11351 | -0.025 | -0.2821 | No | ||
85 | STK35 | 14851 | 11969 | -0.033 | -0.3151 | No | ||
86 | E2F3 | 21500 8874 | 12512 | -0.042 | -0.3438 | No | ||
87 | CDC6 | 6221 6220 | 12726 | -0.046 | -0.3547 | No | ||
88 | SYNGR4 | 17825 | 12882 | -0.048 | -0.3624 | No | ||
89 | NELL2 | 12006 7020 22151 | 12894 | -0.049 | -0.3624 | No | ||
90 | KCNA6 | 664 16990 665 4938 | 13086 | -0.053 | -0.3720 | No | ||
91 | H2AFZ | 6957 | 13142 | -0.054 | -0.3742 | No | ||
92 | EPHB1 | 19024 | 13254 | -0.057 | -0.3794 | No | ||
93 | RRM2 | 5401 5400 | 13608 | -0.067 | -0.3976 | No | ||
94 | PVRL1 | 3006 19482 12211 7192 | 13915 | -0.078 | -0.4131 | No | ||
95 | MCM6 | 4000 13845 4119 | 14373 | -0.097 | -0.4365 | No | ||
96 | SLCO3A1 | 17796 4237 8430 | 14526 | -0.105 | -0.4433 | No | ||
97 | CLSPN | 16079 11256 6530 | 14635 | -0.111 | -0.4476 | No | ||
98 | HNRPA2B1 | 1187 7001 7000 1040 | 14665 | -0.112 | -0.4476 | No | ||
99 | TYRO3 | 5811 | 14772 | -0.118 | -0.4517 | No | ||
100 | HNRPUL1 | 6118 17923 1608 10577 1345 | 14839 | -0.123 | -0.4535 | No | ||
101 | TOPBP1 | 10659 | 14925 | -0.130 | -0.4563 | No | ||
102 | PRPS2 | 24003 | 14976 | -0.134 | -0.4571 | No | ||
103 | E2F1 | 14384 | 15142 | -0.148 | -0.4640 | No | ||
104 | EFNA5 | 4655 8884 | 15321 | -0.166 | -0.4714 | No | ||
105 | PHF15 | 20467 8050 | 15540 | -0.195 | -0.4804 | No | ||
106 | AP4M1 | 3499 16656 | 15584 | -0.201 | -0.4800 | No | ||
107 | HOXC10 | 22342 | 15638 | -0.209 | -0.4799 | No | ||
108 | POLR2A | 5394 | 15739 | -0.224 | -0.4822 | No | ||
109 | ASXL2 | 7957 | 15838 | -0.241 | -0.4842 | No | ||
110 | PHC1 | 17013 | 15853 | -0.244 | -0.4815 | No | ||
111 | CCNT1 | 22140 11607 | 15926 | -0.256 | -0.4818 | No | ||
112 | PHF5A | 22194 | 15960 | -0.263 | -0.4800 | No | ||
113 | RPS20 | 7438 | 16077 | -0.290 | -0.4822 | No | ||
114 | POLD3 | 17742 | 16285 | -0.340 | -0.4887 | Yes | ||
115 | GMNN | 21513 | 16323 | -0.351 | -0.4858 | Yes | ||
116 | SNRPD1 | 23622 | 16386 | -0.368 | -0.4840 | Yes | ||
117 | NUP62 | 9497 | 16415 | -0.377 | -0.4802 | Yes | ||
118 | HIST1H4A | 11590 | 16440 | -0.384 | -0.4762 | Yes | ||
119 | ING3 | 17514 1019 | 16481 | -0.391 | -0.4729 | Yes | ||
120 | MCM2 | 17074 | 16584 | -0.423 | -0.4725 | Yes | ||
121 | ACBD6 | 14089 | 16627 | -0.439 | -0.4687 | Yes | ||
122 | HIST1H2AH | 11414 | 16630 | -0.439 | -0.4626 | Yes | ||
123 | POLE4 | 12441 | 16649 | -0.448 | -0.4574 | Yes | ||
124 | GPRC5B | 17662 | 16662 | -0.452 | -0.4517 | Yes | ||
125 | SLC25A3 | 19644 | 16670 | -0.456 | -0.4457 | Yes | ||
126 | SUV39H1 | 24194 | 16674 | -0.458 | -0.4395 | Yes | ||
127 | MYH10 | 8077 | 16724 | -0.474 | -0.4355 | Yes | ||
128 | AK2 | 8563 2479 16073 | 16848 | -0.535 | -0.4347 | Yes | ||
129 | PPM1D | 20721 | 17001 | -0.588 | -0.4348 | Yes | ||
130 | H2AFV | 1273 20531 | 17017 | -0.596 | -0.4272 | Yes | ||
131 | USP37 | 13923 | 17077 | -0.623 | -0.4217 | Yes | ||
132 | PIM1 | 23308 | 17127 | -0.645 | -0.4154 | Yes | ||
133 | FHOD1 | 18772 | 17130 | -0.646 | -0.4065 | Yes | ||
134 | ACO2 | 8527 | 17408 | -0.809 | -0.4102 | Yes | ||
135 | CDT1 | 18437 | 17522 | -0.874 | -0.4041 | Yes | ||
136 | CDCA7 | 12437 | 17611 | -0.932 | -0.3959 | Yes | ||
137 | NOLC1 | 7704 | 17688 | -0.989 | -0.3862 | Yes | ||
138 | HTF9C | 4886 1678 | 17690 | -0.992 | -0.3724 | Yes | ||
139 | KPNB1 | 20274 | 17794 | -1.043 | -0.3634 | Yes | ||
140 | NCL | 5153 13899 | 17866 | -1.091 | -0.3520 | Yes | ||
141 | DCK | 16808 | 17883 | -1.106 | -0.3375 | Yes | ||
142 | POLD1 | 17847 | 17890 | -1.117 | -0.3222 | Yes | ||
143 | GSPT1 | 9046 | 17911 | -1.132 | -0.3075 | Yes | ||
144 | FKBP5 | 23051 | 18065 | -1.288 | -0.2978 | Yes | ||
145 | PCNA | 9535 | 18149 | -1.424 | -0.2824 | Yes | ||
146 | SUMO1 | 5826 3943 10247 | 18207 | -1.537 | -0.2640 | Yes | ||
147 | UGCGL1 | 6721 | 18270 | -1.619 | -0.2448 | Yes | ||
148 | TMPO | 5778 | 18301 | -1.680 | -0.2230 | Yes | ||
149 | RBBP4 | 5364 | 18347 | -1.797 | -0.2003 | Yes | ||
150 | UNG | 10257 16744 | 18367 | -1.876 | -0.1752 | Yes | ||
151 | PRPS1 | 24233 | 18424 | -2.091 | -0.1490 | Yes | ||
152 | AP1S1 | 3500 3453 16335 | 18426 | -2.099 | -0.1198 | Yes | ||
153 | MSH2 | 23138 | 18433 | -2.139 | -0.0902 | Yes | ||
154 | SFRS10 | 9818 1722 5441 | 18461 | -2.231 | -0.0606 | Yes | ||
155 | CDC5L | 7746 7745 7744 | 18493 | -2.351 | -0.0294 | Yes | ||
156 | NASP | 2383 2387 6955 | 18526 | -2.581 | 0.0049 | Yes |