Details for gene set HSA04530_TIGHT

Table: GSEA Results Summary

Dataset	Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB
Phenotype	phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB
Upregulated in class	LMproB
GeneSet	HSA04530_TIGHT_JUNCTION
Enrichment Score (ES)	-0.5505098
Normalized Enrichment Score (NES)	-1.433801
Nominal p-value	0.01002004
FDR q-value	0.80578804
FWER p-Value	0.999

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PRKCD	21897	229	2.169	0.0357	No
2	PRKCB1	1693 9574	479	1.540	0.0564	No
3	RRAS	18256	739	1.158	0.0681	No
4	TJP3	19677 3298	868	1.039	0.0842	No
5	MYLPF	18069	1021	0.944	0.0970	No
6	ACTN4	17905 1798 1983	1141	0.856	0.1095	No
7	AKT3	13739 982	1301	0.740	0.1173	No
8	CLDN1	22623	1867	0.471	0.0973	No
9	MYL2	16713	2079	0.387	0.0945	No
10	PRKCZ	5260	2200	0.352	0.0958	No
11	CLDN15	16667 3572	2368	0.307	0.0936	No
12	CLDN5	22826	2571	0.260	0.0884	No
13	CSNK2A1	14797	2794	0.214	0.0812	No
14	MYH7	21828 4709	2923	0.196	0.0786	No
15	JAM2	7428 22718 12519	2963	0.192	0.0808	No
16	INADL	2517 2403 165 2347 166	3076	0.176	0.0786	No
17	MYL9	14767 2659	3098	0.174	0.0814	No
18	CLDN23	18893	3255	0.156	0.0764	No
19	EXOC3	9986	3352	0.145	0.0744	No
20	CASK	24184 2618 2604	3500	0.131	0.0694	No
21	VAPA	22908	3566	0.124	0.0686	No
22	MYH9	2252 2244	3601	0.122	0.0695	No
23	PTEN	5305	3651	0.119	0.0695	No
24	CLDN10	21935 2785 2601 2720 7188	3834	0.106	0.0620	No
25	MYL7	9437	3877	0.104	0.0621	No
26	CLDN9	24470	4243	0.084	0.0442	No
27	PPP2R4	15050 2910	4911	0.061	0.0095	No
28	MYH11	22656	5049	0.057	0.0034	No
29	CRB3	23176	5306	0.051	-0.0093	No
30	JAM3	8197	5839	0.040	-0.0371	No
31	CLDN7	20817	5943	0.038	-0.0418	No
32	CLDN11	15616	6223	0.034	-0.0562	No
33	PRKCE	9575	6468	0.029	-0.0687	No
34	ACTG1	8535	6846	0.024	-0.0885	No
35	MRAS	9409	7050	0.022	-0.0990	No
36	AKT1	8568	7183	0.020	-0.1057	No
37	CLDN8	22549 1747	8013	0.010	-0.1502	No
38	CLDN2	4527	8176	0.008	-0.1588	No
39	MYH3	20839	8512	0.005	-0.1768	No
40	CTTN	8817 4575 1035 8818	8823	0.001	-0.1935	No
41	YES1	5930	9040	-0.001	-0.2051	No
42	PRKCQ	2873 2831	9370	-0.004	-0.2228	No
43	MAGI1	19828 4816 1179	9454	-0.005	-0.2272	No
44	RHOA	8624 4409 4410	9584	-0.006	-0.2340	No
45	PRKCI	9576	9792	-0.008	-0.2450	No
46	AKT2	4365 4366	9915	-0.009	-0.2514	No
47	MYH4	20837	10179	-0.012	-0.2653	No
48	GNAI1	9024	10182	-0.012	-0.2652	No
49	RAB13	15535	10212	-0.012	-0.2665	No
50	PPP2R2A	3222 21774	10353	-0.013	-0.2737	No
51	PARD6B	12209	10710	-0.018	-0.2926	No
52	PARD3	8212 13553	10948	-0.020	-0.3049	No
53	CSNK2B	23008	11034	-0.021	-0.3090	No
54	CGN	12896 12897 7701	11205	-0.023	-0.3177	No
55	MYH2	20838	11231	-0.024	-0.3185	No
56	RAB3B	16141	11633	-0.029	-0.3395	No
57	MYH6	9436	11876	-0.032	-0.3519	No
58	CLDN19	16105 472	12028	-0.034	-0.3593	No
59	MPDZ	2497 2366 9406	12086	-0.035	-0.3616	No
60	GNAI3	15198	12279	-0.038	-0.3711	No
61	MPP5	21230 7078	12431	-0.041	-0.3783	No
62	NRAS	5191	12493	-0.042	-0.3807	No
63	CLDN14	12081	12600	-0.043	-0.3855	No
64	SRC	5507	12732	-0.046	-0.3915	No
65	CLDN17	10757	12817	-0.047	-0.3950	No
66	MYH14	17845	13003	-0.051	-0.4039	No
67	CLDN18	19028	13162	-0.054	-0.4112	No
68	CLDN16	22802	13330	-0.059	-0.4189	No
69	CDC42	4503 8722 4504 2465	13369	-0.060	-0.4197	No
70	TJP1	17803	13390	-0.060	-0.4194	No
71	PPM1J	15466 12971	13763	-0.072	-0.4379	No
72	OCLN	21368	14015	-0.082	-0.4496	No
73	TJP2	5761 3699	14043	-0.083	-0.4492	No
74	CLDN3	16680	14046	-0.083	-0.4475	No
75	ACTN3	23967 8540	14262	-0.092	-0.4571	No
76	F11R	9199	14381	-0.097	-0.4613	No
77	PPP2CB	18636	15083	-0.143	-0.4960	No
78	ACTN2	21545	15268	-0.160	-0.5024	No
79	PPP2CA	20890	16118	-0.299	-0.5416	No
80	PPP2R1A	11951	16124	-0.301	-0.5352	No
81	PARD6G	23503	16409	-0.375	-0.5422	Yes
82	PARD6A	12142	16545	-0.411	-0.5404	Yes
83	PRKCA	20174	16682	-0.460	-0.5375	Yes
84	MYH10	8077	16724	-0.474	-0.5292	Yes
85	ASH1L	5311 15546 15547	16772	-0.497	-0.5207	Yes
86	CLDN4	8747	17169	-0.663	-0.5274	Yes
87	KRAS	9247	17394	-0.797	-0.5218	Yes
88	HRAS	4868	17672	-0.978	-0.5151	Yes
89	HCLS1	22770	17831	-1.068	-0.5000	Yes
90	CDK4	3424 19859	17842	-1.076	-0.4766	Yes
91	CSDA	1163 16966 1134	18129	-1.394	-0.4612	Yes
92	PRKCH	21246	18213	-1.553	-0.4312	Yes
93	ACTB	8534 337 337 338	18221	-1.558	-0.3970	Yes
94	CSNK2A2	4567 8808	18260	-1.597	-0.3637	Yes
95	RRAS2	12431	18490	-2.316	-0.3247	Yes
96	EXOC4	17493	18557	-2.919	-0.2635	Yes
97	MYLC2PL	16670	18606	-5.102	-0.1530	Yes
98	AMOTL1	19242	18612	-6.921	0.0002	Yes