Details for gene set HSA04115_P53_SIGNALING

Table: GSEA Results Summary

Dataset	Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB
Phenotype	phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB
Upregulated in class	LMproB
GeneSet	HSA04115_P53_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.63136894
Normalized Enrichment Score (NES)	-1.5428337
Nominal p-value	0.0020491802
FDR q-value	0.52564365
FWER p-Value	0.936

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CD82	8720	17	4.567	0.1085	No
2	GADD45G	21637	401	1.662	0.1276	No
3	CCNB1	11201 21362	1651	0.559	0.0737	No
4	CDK2	3438 3373 19592 3322	1686	0.541	0.0848	No
5	GADD45B	19935	2318	0.321	0.0585	No
6	ATR	19349	2673	0.238	0.0451	No
7	CCNE1	17857	2685	0.235	0.0502	No
8	IGF1	3352 9156 3409	2811	0.211	0.0485	No
9	CCND3	4489 4490	2917	0.197	0.0475	No
10	BID	17017 435	3229	0.158	0.0346	No
11	DDB2	2721 2878 14525 2661	3439	0.137	0.0266	No
12	PTEN	5305	3651	0.119	0.0181	No
13	TNFRSF10B	21971 10205 5781 10204	3714	0.114	0.0174	No
14	MDM2	19620 3327	3820	0.107	0.0144	No
15	SESN2	15733	3933	0.100	0.0107	No
16	CCND1	4487 4488 8707 17535	4372	0.079	-0.0110	No
17	RCHY1	12646	4499	0.074	-0.0160	No
18	CCNB2	19067	5368	0.050	-0.0616	No
19	THBS1	5748 14910	5461	0.047	-0.0654	No
20	SFN	7060 12062	5653	0.044	-0.0747	No
21	GTSE1	11385 2170	5739	0.042	-0.0783	No
22	CASP9	16001 2410 2458	6938	0.023	-0.1423	No
23	IGFBP3	4898	7198	0.020	-0.1558	No
24	ATM	2976 19115	7356	0.018	-0.1638	No
25	LRDD	17555	7957	0.011	-0.1959	No
26	SERPINE1	16333	8035	0.010	-0.1998	No
27	MDM4	5086 5085	8620	0.004	-0.2312	No
28	RPRM	14588	9191	-0.002	-0.2618	No
29	SERPINB5	9861	9780	-0.008	-0.2933	No
30	PERP	2259 22121 20085	10068	-0.011	-0.3085	No
31	CCNB3	24205	10095	-0.011	-0.3097	No
32	RRM2B	6902 6903 11801	11033	-0.021	-0.3597	No
33	BAI1	22459	12338	-0.039	-0.4290	No
34	PMAIP1	23530 12216 7196	12936	-0.049	-0.4600	No
35	CHEK2	16751 3587	13353	-0.059	-0.4810	No
36	RRM2	5401 5400	13608	-0.067	-0.4931	No
37	BBC3	18382 2044	13733	-0.071	-0.4980	No
38	GADD45A	17129	14250	-0.091	-0.5237	No
39	CDKN2A	2491 15841	14297	-0.093	-0.5239	No
40	CCNG1	4492 1236 1390	15406	-0.176	-0.5794	No
41	FAS	23881 3750	15661	-0.211	-0.5880	No
42	CCNG2	16790	15942	-0.259	-0.5969	No
43	CHEK1	19181 3085	16177	-0.313	-0.6021	No
44	CDK6	16600	16722	-0.473	-0.6200	Yes
45	TSC2	23090	16727	-0.475	-0.6089	Yes
46	APAF1	8606	16795	-0.511	-0.6002	Yes
47	PPM1D	20721	17001	-0.588	-0.5972	Yes
48	CYCS	8821	17152	-0.657	-0.5896	Yes
49	SESN3	19561	17492	-0.860	-0.5872	Yes
50	CASP8	8694	17804	-1.050	-0.5788	Yes
51	CDK4	3424 19859	17842	-1.076	-0.5551	Yes
52	SESN1	20045	17884	-1.107	-0.5308	Yes
53	SCOTIN	3136 19299 3102	18047	-1.277	-0.5089	Yes
54	CCNE2	4491	18137	-1.408	-0.4800	Yes
55	EI24	19179	18159	-1.436	-0.4467	Yes
56	CASP3	8693	18250	-1.583	-0.4136	Yes
57	CDKN1A	4511 8729	18443	-2.164	-0.3722	Yes
58	BAX	17832	18570	-3.065	-0.3056	Yes
59	ZMAT3	10305	18581	-3.349	-0.2259	Yes
60	CCND2	16987	18590	-3.849	-0.1341	Yes
61	TP53	20822	18609	-5.657	0.0004	Yes