Details for gene set HSA00240_PYRIMIDINE

Table: GSEA Results Summary

Dataset	Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB
Phenotype	phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB
Upregulated in class	LMproB
GeneSet	HSA00240_PYRIMIDINE_METABOLISM
Enrichment Score (ES)	-0.5828028
Normalized Enrichment Score (NES)	-1.4547814
Nominal p-value	0.0061099795
FDR q-value	0.7781641
FWER p-Value	0.999

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CTPS	2514 15772	226	2.192	0.0420	No
2	RRM1	18163	443	1.598	0.0698	No
3	POLR2E	3325 19699	848	1.057	0.0742	No
4	POLE	16755	1260	0.773	0.0711	No
5	POLR2J	16672	1382	0.698	0.0818	No
6	POLR3A	21900	1533	0.612	0.0889	No
7	TYMS	5810 5809 3606 3598	1714	0.531	0.0923	No
8	NT5C2	3768 8052	1969	0.429	0.0892	No
9	POLR2I	12839	2080	0.387	0.0928	No
10	POLD4	12822	2108	0.380	0.1008	No
11	TK2	18779	2453	0.286	0.0893	No
12	NME6	3139 19297	2935	0.195	0.0681	No
13	POLR2G	23753	3165	0.165	0.0599	No
14	ECGF1	22160	3461	0.136	0.0473	No
15	NT5E	19360 18702	3552	0.126	0.0456	No
16	TXNRD1	19923	3791	0.109	0.0354	No
17	TXNRD2	22829 1649	3975	0.098	0.0280	No
18	ENTPD6	4496 2678	4289	0.082	0.0131	No
19	UPP1	20947 1385	4796	0.064	-0.0126	No
20	PNPT1	20936	4812	0.063	-0.0119	No
21	NT5M	8345 4175	4869	0.062	-0.0134	No
22	NME7	926 4101 14070 3986 3946 931	5139	0.055	-0.0265	No
23	ENTPD8	12996	5324	0.051	-0.0352	No
24	POLR2C	9750	6273	0.033	-0.0855	No
25	POLA1	24112	7186	0.020	-0.1342	No
26	DPYD	15437	7442	0.017	-0.1475	No
27	ENTPD1	4495	7584	0.015	-0.1548	No
28	CAD	16886	7836	0.012	-0.1680	No
29	POLR2B	16817	7994	0.011	-0.1762	No
30	ITPA	9193	8226	0.008	-0.1885	No
31	POLE2	21053	9793	-0.008	-0.2727	No
32	RRM2B	6902 6903 11801	11033	-0.021	-0.3390	No
33	DPYS	22305	11445	-0.026	-0.3606	No
34	UPP2	15009 13346 8032	11613	-0.029	-0.3689	No
35	ENTPD3	19266	11767	-0.031	-0.3763	No
36	POLR3K	12447 7372	12460	-0.041	-0.4127	No
37	ENTPD4	7449	12953	-0.050	-0.4380	No
38	UPB1	19988 3389	13250	-0.057	-0.4525	No
39	RRM2	5401 5400	13608	-0.067	-0.4701	No
40	POLR1D	3593 3658 16623	13620	-0.067	-0.4691	No
41	CTPS2	12060 2571	13800	-0.074	-0.4769	No
42	POLR1B	14857	13878	-0.077	-0.4791	No
43	CANT1	13304	13913	-0.078	-0.4790	No
44	CDA	15702	14042	-0.083	-0.4839	No
45	NT5C1B	21315	14402	-0.098	-0.5008	No
46	AICDA	17295 1087	14659	-0.112	-0.5119	No
47	POLR2A	5394	15739	-0.224	-0.5645	No
48	NT5C	20151	16079	-0.290	-0.5756	Yes
49	NUDT2	16239	16139	-0.303	-0.5713	Yes
50	POLD3	17742	16285	-0.340	-0.5707	Yes
51	DHODH	7152	16332	-0.354	-0.5645	Yes
52	UCK1	10254 5831 10253	16334	-0.355	-0.5558	Yes
53	DTYMK	5776	16607	-0.430	-0.5598	Yes
54	POLE4	12441	16649	-0.448	-0.5510	Yes
55	POLR1A	9749 5393	16667	-0.453	-0.5407	Yes
56	POLR2K	9413	16723	-0.474	-0.5319	Yes
57	POLR3H	13460 8135	16779	-0.501	-0.5225	Yes
58	POLE3	7200	16807	-0.514	-0.5113	Yes
59	NT5C3	17136	16967	-0.577	-0.5056	Yes
60	TK1	1457 10182 5762	17162	-0.661	-0.4997	Yes
61	POLD2	20537	17321	-0.752	-0.4897	Yes
62	DCTD	18620	17333	-0.760	-0.4715	Yes
63	POLA2	23988	17453	-0.841	-0.4571	Yes
64	ZNRD1	1491 22987	17463	-0.845	-0.4367	Yes
65	POLR3B	12875	17628	-0.943	-0.4222	Yes
66	PRIM1	19847	17717	-1.000	-0.4023	Yes
67	POLR2H	10888	17762	-1.025	-0.3793	Yes
68	DCK	16808	17883	-1.106	-0.3584	Yes
69	POLD1	17847	17890	-1.117	-0.3312	Yes
70	NME4	23065 1577	17983	-1.193	-0.3066	Yes
71	ENTPD5	4497	17993	-1.200	-0.2775	Yes
72	NP	22027 9597 5273 5274	18241	-1.580	-0.2517	Yes
73	NME2	9468	18261	-1.599	-0.2132	Yes
74	NME1	9467	18275	-1.635	-0.1735	Yes
75	UMPS	22606 1760	18545	-2.771	-0.1195	Yes
76	RFC5	13005 7791	18605	-4.988	0.0006	Yes