Details for gene set HSA00230_PURINE

Table: GSEA Results Summary

Dataset	Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB
Phenotype	phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB
Upregulated in class	LMproB
GeneSet	HSA00230_PURINE_METABOLISM
Enrichment Score (ES)	-0.569267
Normalized Enrichment Score (NES)	-1.5154941
Nominal p-value	0.0022222223
FDR q-value	0.47260392
FWER p-Value	0.981

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	XDH	22897	172	2.458	0.0311	No
2	RRM1	18163	443	1.598	0.0428	No
3	PDE6D	13897 3945	446	1.588	0.0688	No
4	POLR2E	3325 19699	848	1.057	0.0644	No
5	PDE4B	9543	957	0.993	0.0749	No
6	POLE	16755	1260	0.773	0.0713	No
7	ADCY9	22680	1362	0.708	0.0775	No
8	POLR2J	16672	1382	0.698	0.0879	No
9	FHIT	21920	1419	0.672	0.0970	No
10	POLR3A	21900	1533	0.612	0.1009	No
11	ENPP1	19804	1810	0.495	0.0941	No
12	NT5C2	3768 8052	1969	0.429	0.0927	No
13	POLR2I	12839	2080	0.387	0.0931	No
14	POLD4	12822	2108	0.380	0.0979	No
15	PDE4C	8481	2700	0.231	0.0697	No
16	ADCY6	22139 2283 8551	2802	0.213	0.0677	No
17	HPRT1	2655 24339 408	2870	0.203	0.0674	No
18	NME6	3139 19297	2935	0.195	0.0672	No
19	POLR2G	23753	3165	0.165	0.0575	No
20	AMPD1	5051	3221	0.159	0.0571	No
21	ECGF1	22160	3461	0.136	0.0465	No
22	NT5E	19360 18702	3552	0.126	0.0436	No
23	GDA	4764	3655	0.118	0.0401	No
24	GUCY1B3	15311	3659	0.118	0.0419	No
25	PDE4A	3037 19542 3083 3023	3793	0.109	0.0365	No
26	PKLR	1850 15545	3825	0.107	0.0365	No
27	GUCY1A3	7216 12245 15310	3878	0.104	0.0354	No
28	PDE7B	19807	3945	0.099	0.0335	No
29	ENTPD6	4496 2678	4289	0.082	0.0163	No
30	AK1	4363	4453	0.075	0.0087	No
31	PNPT1	20936	4812	0.063	-0.0096	No
32	NT5M	8345 4175	4869	0.062	-0.0116	No
33	NME7	926 4101 14070 3986 3946 931	5139	0.055	-0.0253	No
34	ENTPD8	12996	5324	0.051	-0.0344	No
35	AMPD3	4383 2110	5358	0.050	-0.0354	No
36	GMPR2	2711	5453	0.047	-0.0397	No
37	PDE8B	5756	5919	0.039	-0.0642	No
38	POLR2C	9750	6273	0.033	-0.0828	No
39	PDE9A	23301	6696	0.026	-0.1052	No
40	PDE1C	5235	6711	0.026	-0.1055	No
41	ADCY5	10312	6874	0.024	-0.1139	No
42	AK5	6042	6941	0.023	-0.1171	No
43	PDE10A	23387	6965	0.023	-0.1179	No
44	ALLC	21093 2130	7077	0.021	-0.1236	No
45	ADCY2	21412	7144	0.020	-0.1268	No
46	GUCY2C	1140 16954	7164	0.020	-0.1275	No
47	POLA1	24112	7186	0.020	-0.1283	No
48	PDE6G	20119	7506	0.016	-0.1453	No
49	ENTPD1	4495	7584	0.015	-0.1492	No
50	GUCY2F	24045	7880	0.012	-0.1650	No
51	POLR2B	16817	7994	0.011	-0.1709	No
52	ITPA	9193	8226	0.008	-0.1833	No
53	PDE11A	10805	8385	0.006	-0.1917	No
54	ADCY3	21329 894	9063	-0.001	-0.2283	No
55	ADCY8	22281	9222	-0.003	-0.2368	No
56	ADK	3302 3454 8555	9381	-0.004	-0.2453	No
57	POLE2	21053	9793	-0.008	-0.2674	No
58	ADCY4	2980 21818	10065	-0.011	-0.2819	No
59	PAPSS2	6258	10972	-0.020	-0.3306	No
60	RRM2B	6902 6903 11801	11033	-0.021	-0.3335	No
61	ENTPD3	19266	11767	-0.031	-0.3726	No
62	ENTPD2	8713	11794	-0.031	-0.3735	No
63	NPR2	16230	11798	-0.031	-0.3731	No
64	PDE6H	17257	12060	-0.035	-0.3867	No
65	AMPD2	1931 15197	12264	-0.038	-0.3970	No
66	POLR3K	12447 7372	12460	-0.041	-0.4069	No
67	ENTPD4	7449	12953	-0.050	-0.4327	No
68	AK3L1	8564	13139	-0.054	-0.4418	No
69	GUCY1A2	19580	13226	-0.056	-0.4456	No
70	ENPP3	19803	13530	-0.065	-0.4609	No
71	RRM2	5401 5400	13608	-0.067	-0.4640	No
72	POLR1D	3593 3658 16623	13620	-0.067	-0.4634	No
73	PDE1A	9541 5234	13638	-0.068	-0.4633	No
74	POLR1B	14857	13878	-0.077	-0.4749	No
75	CANT1	13304	13913	-0.078	-0.4755	No
76	GART	22543 1754	14175	-0.088	-0.4881	No
77	NT5C1B	21315	14402	-0.098	-0.4987	No
78	PRPS2	24003	14976	-0.134	-0.5275	No
79	PDE4D	10722 6235	15012	-0.136	-0.5272	No
80	NPR1	9480	15719	-0.220	-0.5618	No
81	POLR2A	5394	15739	-0.224	-0.5591	No
82	IMPDH1	17197 1131	15783	-0.231	-0.5576	No
83	APRT	8620	15948	-0.260	-0.5622	No
84	NT5C	20151	16079	-0.290	-0.5645	Yes
85	IMPDH2	10730	16083	-0.291	-0.5599	Yes
86	DGUOK	17099 1041	16105	-0.297	-0.5561	Yes
87	NUDT2	16239	16139	-0.303	-0.5529	Yes
88	PKM2	3642 9573	16260	-0.334	-0.5539	Yes
89	POLD3	17742	16285	-0.340	-0.5497	Yes
90	ADA	2703 14361	16439	-0.384	-0.5516	Yes
91	POLE4	12441	16649	-0.448	-0.5556	Yes
92	POLR1A	9749 5393	16667	-0.453	-0.5491	Yes
93	PDE7A	9544 1788	16673	-0.458	-0.5418	Yes
94	PDE5A	15431	16683	-0.460	-0.5347	Yes
95	POLR2K	9413	16723	-0.474	-0.5290	Yes
96	PAPSS1	15419	16763	-0.494	-0.5230	Yes
97	POLR3H	13460 8135	16779	-0.501	-0.5156	Yes
98	POLE3	7200	16807	-0.514	-0.5086	Yes
99	AK2	8563 2479 16073	16848	-0.535	-0.5020	Yes
100	NT5C3	17136	16967	-0.577	-0.4989	Yes
101	PDE2A	18170	16983	-0.583	-0.4901	Yes
102	PAICS	16820	16990	-0.585	-0.4809	Yes
103	GMPR	21651	17049	-0.609	-0.4740	Yes
104	NUDT9	7897	17087	-0.627	-0.4657	Yes
105	GUK1	20432	17167	-0.661	-0.4591	Yes
106	POLD2	20537	17321	-0.752	-0.4550	Yes
107	PDE3B	5236	17380	-0.788	-0.4452	Yes
108	GMPS	15578	17439	-0.831	-0.4346	Yes
109	POLA2	23988	17453	-0.841	-0.4215	Yes
110	ZNRD1	1491 22987	17463	-0.845	-0.4081	Yes
111	ADSL	4358	17553	-0.892	-0.3983	Yes
112	PDE8A	18202	17560	-0.895	-0.3839	Yes
113	POLR3B	12875	17628	-0.943	-0.3720	Yes
114	ADCY7	8552 448	17689	-0.991	-0.3590	Yes
115	PRIM1	19847	17717	-1.000	-0.3440	Yes
116	POLR2H	10888	17762	-1.025	-0.3295	Yes
117	DCK	16808	17883	-1.106	-0.3178	Yes
118	POLD1	17847	17890	-1.117	-0.2998	Yes
119	NME4	23065 1577	17983	-1.193	-0.2852	Yes
120	ENTPD5	4497	17993	-1.200	-0.2659	Yes
121	ATIC	14231 3968	18136	-1.404	-0.2505	Yes
122	PPAT	6081	18153	-1.431	-0.2279	Yes
123	NP	22027 9597 5273 5274	18241	-1.580	-0.2066	Yes
124	ADSSL1	21136 2087	18254	-1.591	-0.1811	Yes
125	NME2	9468	18261	-1.599	-0.1552	Yes
126	NME1	9467	18275	-1.635	-0.1290	Yes
127	NUDT5	15121	18369	-1.880	-0.1031	Yes
128	PRPS1	24233	18424	-2.091	-0.0717	Yes
129	RFC5	13005 7791	18605	-4.988	0.0006	Yes