Dataset | Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB |
Phenotype | phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB |
Upregulated in class | LMproB |
GeneSet | REACTOME_DIABETES_PATHWAYS |
Enrichment Score (ES) | -0.5816019 |
Normalized Enrichment Score (NES) | -1.5980545 |
Nominal p-value | 0.0 |
FDR q-value | 0.34375668 |
FWER p-Value | 0.841 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | IQGAP1 | 6619 | 228 | 2.181 | 0.0181 | No | ||
2 | CS | 19839 | 418 | 1.641 | 0.0308 | No | ||
3 | OGDH | 9502 1412 | 946 | 0.997 | 0.0162 | No | ||
4 | SSR2 | 15549 | 1076 | 0.914 | 0.0219 | No | ||
5 | COX6B1 | 4283 8479 | 1214 | 0.803 | 0.0257 | No | ||
6 | ETFB | 18279 | 1255 | 0.775 | 0.0344 | No | ||
7 | IGFBP5 | 4899 | 1322 | 0.728 | 0.0410 | No | ||
8 | RPS3 | 6549 11295 | 1418 | 0.673 | 0.0452 | No | ||
9 | NDUFS3 | 7553 12683 | 1439 | 0.661 | 0.0534 | No | ||
10 | RPS29 | 9754 | 1483 | 0.636 | 0.0599 | No | ||
11 | DLD | 2097 21090 | 1712 | 0.532 | 0.0550 | No | ||
12 | RPS5 | 18391 | 1719 | 0.529 | 0.0620 | No | ||
13 | NDUFA6 | 12473 | 1930 | 0.445 | 0.0569 | No | ||
14 | EXOC8 | 4161 | 1954 | 0.434 | 0.0617 | No | ||
15 | NDUFS4 | 9452 5157 3173 | 1957 | 0.433 | 0.0676 | No | ||
16 | NDUFA2 | 9450 | 1965 | 0.431 | 0.0733 | No | ||
17 | PLA2G7 | 23233 | 2351 | 0.312 | 0.0568 | No | ||
18 | RPS25 | 13270 | 2457 | 0.285 | 0.0551 | No | ||
19 | RPS15A | 6476 | 2521 | 0.271 | 0.0554 | No | ||
20 | RPL11 | 12450 | 2808 | 0.212 | 0.0429 | No | ||
21 | IGF1 | 3352 9156 3409 | 2811 | 0.211 | 0.0457 | No | ||
22 | KLF4 | 9230 4962 4963 | 2856 | 0.205 | 0.0462 | No | ||
23 | RPLP1 | 3010 | 2986 | 0.189 | 0.0419 | No | ||
24 | FAU | 8954 | 3142 | 0.168 | 0.0358 | No | ||
25 | NDUFS8 | 23950 | 3289 | 0.152 | 0.0300 | No | ||
26 | RPL37A | 9744 | 3372 | 0.144 | 0.0276 | No | ||
27 | NDUFA7 | 12347 | 3395 | 0.141 | 0.0284 | No | ||
28 | KCNJ11 | 17822 | 4041 | 0.093 | -0.0053 | No | ||
29 | RPL19 | 9736 | 4283 | 0.082 | -0.0172 | No | ||
30 | SLC2A2 | 15623 1880 1855 | 4540 | 0.072 | -0.0300 | No | ||
31 | COX7C | 8776 | 4584 | 0.071 | -0.0314 | No | ||
32 | GNAS | 9025 2963 2752 | 4797 | 0.064 | -0.0420 | No | ||
33 | SDHB | 2348 12566 14880 | 4828 | 0.063 | -0.0427 | No | ||
34 | RPS17 | 9753 | 5024 | 0.058 | -0.0525 | No | ||
35 | GLP1R | 23304 | 5259 | 0.052 | -0.0644 | No | ||
36 | COX8A | 8777 | 5335 | 0.050 | -0.0678 | No | ||
37 | PGK1 | 9557 5244 | 5417 | 0.048 | -0.0715 | No | ||
38 | KLK3 | 16337 | 5593 | 0.045 | -0.0804 | No | ||
39 | IGFALS | 9158 | 5605 | 0.045 | -0.0803 | No | ||
40 | IGFBP1 | 20948 | 6258 | 0.033 | -0.1152 | No | ||
41 | RPL4 | 7499 19411 | 6687 | 0.026 | -0.1380 | No | ||
42 | SDHA | 12436 | 7043 | 0.022 | -0.1569 | No | ||
43 | UQCRFS1 | 21499 | 7294 | 0.019 | -0.1702 | No | ||
44 | GCG | 14578 | 7323 | 0.018 | -0.1715 | No | ||
45 | PDX1 | 16621 | 7437 | 0.017 | -0.1774 | No | ||
46 | RPLP2 | 7401 | 7509 | 0.016 | -0.1810 | No | ||
47 | RPL27 | 9740 | 7642 | 0.015 | -0.1879 | No | ||
48 | SRP19 | 2004 12341 | 7655 | 0.014 | -0.1884 | No | ||
49 | FFAR1 | 10583 | 7879 | 0.012 | -0.2003 | No | ||
50 | NKX2-2 | 5176 | 7969 | 0.011 | -0.2050 | No | ||
51 | ADRA2A | 4355 | 8476 | 0.005 | -0.2323 | No | ||
52 | PFKFB1 | 9552 | 8573 | 0.004 | -0.2375 | No | ||
53 | RPL17 | 11429 6653 | 8584 | 0.004 | -0.2380 | No | ||
54 | NDUFB4 | 22596 7541 | 8667 | 0.003 | -0.2424 | No | ||
55 | EXOC5 | 8370 | 9466 | -0.005 | -0.2855 | No | ||
56 | EIF2S1 | 4658 | 9487 | -0.005 | -0.2865 | No | ||
57 | RPL39 | 12496 | 9626 | -0.006 | -0.2939 | No | ||
58 | NDUFB8 | 7418 | 9643 | -0.007 | -0.2947 | No | ||
59 | KIF5B | 4955 2031 | 10080 | -0.011 | -0.3182 | No | ||
60 | PFKFB2 | 4116 5242 | 10196 | -0.012 | -0.3242 | No | ||
61 | SYT5 | 17986 | 10282 | -0.013 | -0.3287 | No | ||
62 | RPL28 | 5392 | 10987 | -0.021 | -0.3665 | No | ||
63 | RPL18 | 450 5390 | 11188 | -0.023 | -0.3770 | No | ||
64 | SUCLG1 | 17409 1059 | 11204 | -0.023 | -0.3775 | No | ||
65 | NDUFC1 | 7287 12339 | 11560 | -0.028 | -0.3963 | No | ||
66 | RPS23 | 12352 | 11610 | -0.029 | -0.3986 | No | ||
67 | LEP | 17505 | 11702 | -0.030 | -0.4031 | No | ||
68 | RPS16 | 9752 | 11747 | -0.030 | -0.4051 | No | ||
69 | RAP1A | 8467 | 12046 | -0.035 | -0.4207 | No | ||
70 | ABCC8 | 9941 11649 | 12501 | -0.042 | -0.4447 | No | ||
71 | ATP5J | 880 22555 | 12528 | -0.042 | -0.4456 | No | ||
72 | COX6C | 8775 | 12673 | -0.045 | -0.4527 | No | ||
73 | SRP54 | 6282 | 13473 | -0.063 | -0.4952 | No | ||
74 | PCSK2 | 9537 5231 14824 | 13494 | -0.063 | -0.4954 | No | ||
75 | SEC61B | 12305 7266 | 13764 | -0.072 | -0.5089 | No | ||
76 | MBTPS1 | 18730 3809 3770 | 13875 | -0.077 | -0.5138 | No | ||
77 | NDUFC2 | 18183 | 13896 | -0.078 | -0.5138 | No | ||
78 | RPSA | 19270 4984 | 13981 | -0.081 | -0.5172 | No | ||
79 | IGFBP6 | 9161 | 14303 | -0.094 | -0.5333 | No | ||
80 | NDUFA4 | 9451 | 14472 | -0.102 | -0.5410 | No | ||
81 | NDUFB3 | 12362 | 14503 | -0.104 | -0.5412 | No | ||
82 | PRKAR2B | 5288 2107 | 14536 | -0.105 | -0.5414 | No | ||
83 | ERN1 | 8137 | 14637 | -0.111 | -0.5453 | No | ||
84 | RPL37 | 12502 7421 22521 | 14669 | -0.112 | -0.5454 | No | ||
85 | NDUFA11 | 12832 | 15107 | -0.145 | -0.5671 | No | ||
86 | RPL41 | 12611 | 15183 | -0.152 | -0.5690 | No | ||
87 | MMP2 | 18525 | 15210 | -0.154 | -0.5683 | No | ||
88 | CTSL1 | 4574 | 15269 | -0.160 | -0.5692 | No | ||
89 | CHRM3 | 21547 | 15339 | -0.168 | -0.5706 | No | ||
90 | ATP5G1 | 8636 | 15383 | -0.173 | -0.5705 | No | ||
91 | F2 | 14524 | 15389 | -0.174 | -0.5683 | No | ||
92 | RPS13 | 12633 | 15419 | -0.177 | -0.5674 | No | ||
93 | CPE | 18868 | 15466 | -0.184 | -0.5674 | No | ||
94 | NDUFB10 | 23084 | 15632 | -0.208 | -0.5734 | No | ||
95 | ATP5E | 14321 | 15715 | -0.218 | -0.5748 | No | ||
96 | ATP5F1 | 15212 | 15761 | -0.227 | -0.5741 | No | ||
97 | NDUFAB1 | 7667 | 15901 | -0.250 | -0.5781 | Yes | ||
98 | RPS3A | 9755 | 15917 | -0.254 | -0.5754 | Yes | ||
99 | RPS14 | 9751 | 15920 | -0.255 | -0.5719 | Yes | ||
100 | SRP72 | 16819 | 15964 | -0.263 | -0.5706 | Yes | ||
101 | RPL5 | 9746 | 15976 | -0.266 | -0.5675 | Yes | ||
102 | IGFBP4 | 20670 9160 | 16011 | -0.274 | -0.5655 | Yes | ||
103 | MDH2 | 9399 | 16019 | -0.277 | -0.5620 | Yes | ||
104 | SEC61G | 9795 | 16032 | -0.280 | -0.5587 | Yes | ||
105 | UQCRB | 12545 | 16041 | -0.281 | -0.5552 | Yes | ||
106 | RPS20 | 7438 | 16077 | -0.290 | -0.5531 | Yes | ||
107 | NDUFA9 | 12288 | 16091 | -0.292 | -0.5497 | Yes | ||
108 | NDUFB5 | 12277 | 16162 | -0.309 | -0.5492 | Yes | ||
109 | ATP5O | 22539 | 16182 | -0.314 | -0.5458 | Yes | ||
110 | RPS28 | 12009 | 16221 | -0.324 | -0.5434 | Yes | ||
111 | PKM2 | 3642 9573 | 16260 | -0.334 | -0.5408 | Yes | ||
112 | RPL18A | 13358 | 16304 | -0.347 | -0.5383 | Yes | ||
113 | RPS21 | 12356 | 16336 | -0.356 | -0.5350 | Yes | ||
114 | NFYA | 5172 | 16449 | -0.385 | -0.5357 | Yes | ||
115 | UQCR | 12382 | 16450 | -0.385 | -0.5303 | Yes | ||
116 | SRP14 | 9894 | 16465 | -0.388 | -0.5256 | Yes | ||
117 | HSPA5 | 9045 | 16516 | -0.400 | -0.5227 | Yes | ||
118 | ATP5B | 19846 | 16604 | -0.429 | -0.5215 | Yes | ||
119 | PRKCA | 20174 | 16682 | -0.460 | -0.5192 | Yes | ||
120 | ATP5A1 | 23505 | 16754 | -0.492 | -0.5162 | Yes | ||
121 | IDH3A | 19447 | 16815 | -0.517 | -0.5122 | Yes | ||
122 | DDOST | 16021 | 16820 | -0.520 | -0.5052 | Yes | ||
123 | COX4I1 | 18444 | 16850 | -0.535 | -0.4993 | Yes | ||
124 | COX6A1 | 8774 4553 | 16863 | -0.540 | -0.4924 | Yes | ||
125 | RPL8 | 22437 | 16925 | -0.560 | -0.4879 | Yes | ||
126 | VAMP2 | 20826 | 16932 | -0.562 | -0.4803 | Yes | ||
127 | UQCRC1 | 10259 | 17016 | -0.596 | -0.4765 | Yes | ||
128 | UQCRC2 | 18102 | 17116 | -0.641 | -0.4729 | Yes | ||
129 | CYCS | 8821 | 17152 | -0.657 | -0.4657 | Yes | ||
130 | RPS4X | 9756 | 17191 | -0.675 | -0.4583 | Yes | ||
131 | SEC11A | 12144 | 17213 | -0.689 | -0.4498 | Yes | ||
132 | ETFDH | 15313 | 17275 | -0.725 | -0.4430 | Yes | ||
133 | SSR4 | 24303 5519 | 17441 | -0.833 | -0.4403 | Yes | ||
134 | NDUFS5 | 9296 | 17442 | -0.833 | -0.4287 | Yes | ||
135 | NDUFB7 | 12429 | 17443 | -0.834 | -0.4170 | Yes | ||
136 | RPL14 | 19267 | 17467 | -0.846 | -0.4064 | Yes | ||
137 | ATP5C1 | 8635 | 17480 | -0.854 | -0.3952 | Yes | ||
138 | ATP5D | 19949 | 17558 | -0.895 | -0.3868 | Yes | ||
139 | SDHD | 19125 | 17616 | -0.937 | -0.3769 | Yes | ||
140 | COX7B | 7260 | 17622 | -0.940 | -0.3640 | Yes | ||
141 | ATF4 | 22417 2239 | 17706 | -0.997 | -0.3546 | Yes | ||
142 | NDUFS7 | 19946 | 17711 | -0.999 | -0.3408 | Yes | ||
143 | ATP5J2 | 12186 | 17904 | -1.129 | -0.3355 | Yes | ||
144 | NDUFA8 | 14605 | 17944 | -1.162 | -0.3214 | Yes | ||
145 | RPS2 | 9279 | 18035 | -1.253 | -0.3087 | Yes | ||
146 | RPS19 | 5398 | 18077 | -1.312 | -0.2926 | Yes | ||
147 | NDUFV1 | 23953 | 18079 | -1.321 | -0.2742 | Yes | ||
148 | SLC30A7 | 15186 | 18080 | -1.321 | -0.2558 | Yes | ||
149 | ATP5I | 8637 | 18103 | -1.354 | -0.2381 | Yes | ||
150 | PDHA1 | 24020 | 18104 | -1.355 | -0.2192 | Yes | ||
151 | COX5B | 4552 | 18163 | -1.440 | -0.2022 | Yes | ||
152 | RPL6 | 9747 | 18187 | -1.491 | -0.1826 | Yes | ||
153 | TPI1 | 5795 10212 | 18197 | -1.514 | -0.1620 | Yes | ||
154 | RPL38 | 12562 20606 7475 | 18235 | -1.575 | -0.1420 | Yes | ||
155 | IDH3G | 24132 | 18355 | -1.819 | -0.1230 | Yes | ||
156 | NDUFA10 | 7420 | 18478 | -2.265 | -0.0980 | Yes | ||
157 | NDUFS2 | 4089 13760 | 18485 | -2.303 | -0.0662 | Yes | ||
158 | RPS24 | 5399 | 18502 | -2.395 | -0.0336 | Yes | ||
159 | RPL27A | 11181 6467 18130 | 18549 | -2.846 | 0.0036 | Yes |