Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
| Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
| Upregulated in class | DMpreB |
| GeneSet | DNA_DEPENDENT_DNA_REPLICATION |
| Enrichment Score (ES) | 0.82213765 |
| Normalized Enrichment Score (NES) | 1.7882587 |
| Nominal p-value | 0.0 |
| FDR q-value | 4.4283646E-4 |
| FWER p-Value | 0.0010 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MSH2 | 23138 | 212 | 6.910 | 0.0635 | Yes | ||
| 2 | TIPIN | 3013 7258 | 292 | 6.279 | 0.1274 | Yes | ||
| 3 | GTPBP4 | 21548 | 311 | 6.171 | 0.1933 | Yes | ||
| 4 | RFC1 | 16527 | 335 | 5.989 | 0.2570 | Yes | ||
| 5 | ATR | 19349 | 388 | 5.589 | 0.3148 | Yes | ||
| 6 | MCM3 | 13991 | 390 | 5.583 | 0.3753 | Yes | ||
| 7 | MLH1 | 18982 | 440 | 5.336 | 0.4306 | Yes | ||
| 8 | RFC4 | 1735 22627 | 589 | 4.674 | 0.4733 | Yes | ||
| 9 | RFC3 | 12786 | 722 | 4.193 | 0.5117 | Yes | ||
| 10 | RPA1 | 20349 | 739 | 4.140 | 0.5557 | Yes | ||
| 11 | GMNN | 21513 | 848 | 3.827 | 0.5914 | Yes | ||
| 12 | ORC5L | 11173 3595 | 924 | 3.572 | 0.6261 | Yes | ||
| 13 | PMS2 | 16632 | 1085 | 3.105 | 0.6511 | Yes | ||
| 14 | PRIM1 | 19847 | 1169 | 2.930 | 0.6784 | Yes | ||
| 15 | MSH6 | 23137 5120 | 1249 | 2.764 | 0.7042 | Yes | ||
| 16 | MUTYH | 2400 7693 | 1296 | 2.645 | 0.7304 | Yes | ||
| 17 | CDT1 | 18437 | 1380 | 2.457 | 0.7525 | Yes | ||
| 18 | S100A11 | 9771 | 1585 | 2.144 | 0.7648 | Yes | ||
| 19 | CDK2AP1 | 8858 | 1602 | 2.119 | 0.7869 | Yes | ||
| 20 | POLG2 | 20180 | 1669 | 2.029 | 0.8054 | Yes | ||
| 21 | CDK2 | 3438 3373 19592 3322 | 1846 | 1.753 | 0.8149 | Yes | ||
| 22 | RPA2 | 2330 16057 | 2021 | 1.531 | 0.8221 | Yes | ||
| 23 | MSH3 | 5119 | 2814 | 0.718 | 0.7873 | No | ||
| 24 | MSH5 | 23010 1599 | 3230 | 0.429 | 0.7696 | No | ||
| 25 | RAD51 | 2897 14903 | 3710 | 0.271 | 0.7467 | No | ||
| 26 | ORC4L | 11172 6460 | 4035 | 0.208 | 0.7315 | No | ||
| 27 | GLI2 | 13859 | 4252 | 0.178 | 0.7218 | No | ||
| 28 | RAD17 | 21366 | 4283 | 0.175 | 0.7221 | No | ||
| 29 | PMS1 | 13958 | 4351 | 0.166 | 0.7203 | No | ||
| 30 | NF2 | 1222 5166 | 6068 | 0.064 | 0.6286 | No | ||
| 31 | CDC6 | 6221 6220 | 6125 | 0.063 | 0.6263 | No | ||
| 32 | NBN | 2485 16268 2408 | 6162 | 0.062 | 0.6250 | No | ||
| 33 | TFAM | 19739 3330 | 6619 | 0.051 | 0.6010 | No | ||
| 34 | POLA1 | 24112 | 9841 | 0.001 | 0.4275 | No | ||
| 35 | CDC45L | 22642 1752 | 9951 | -0.001 | 0.4217 | No | ||
| 36 | PURA | 9670 | 10425 | -0.006 | 0.3963 | No | ||
| 37 | EREG | 4679 16797 | 10638 | -0.009 | 0.3850 | No | ||
| 38 | GLI1 | 19605 | 11157 | -0.016 | 0.3572 | No | ||
| 39 | HMGB2 | 13594 | 11502 | -0.021 | 0.3389 | No | ||
| 40 | WRNIP1 | 21675 3161 | 13443 | -0.070 | 0.2352 | No | ||
| 41 | ABL1 | 2693 4301 2794 | 14050 | -0.106 | 0.2037 | No | ||
| 42 | ORC2L | 385 13949 | 14740 | -0.190 | 0.1687 | No | ||
| 43 | RAD9A | 913 3674 910 23958 | 14794 | -0.200 | 0.1680 | No | ||
| 44 | EXO1 | 14035 4135 | 15506 | -0.397 | 0.1340 | No | ||
| 45 | ORC1L | 327 16144 | 15837 | -0.579 | 0.1225 | No | ||
| 46 | REV3L | 20050 | 16103 | -0.827 | 0.1172 | No | ||
| 47 | POLB | 9599 | 16800 | -1.662 | 0.0978 | No |
