Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | WTpreB |
GeneSet | V$OCT1_B |
Enrichment Score (ES) | -0.67631 |
Normalized Enrichment Score (NES) | -1.8097165 |
Nominal p-value | 0.0 |
FDR q-value | 0.0059275064 |
FWER p-Value | 0.0030 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SERTAD4 | 13715 | 438 | 5.350 | 0.0060 | No | ||
2 | PPARGC1B | 9318 | 687 | 4.318 | 0.0166 | No | ||
3 | BLNK | 23681 3691 | 1758 | 1.877 | -0.0310 | No | ||
4 | CDK2 | 3438 3373 19592 3322 | 1846 | 1.753 | -0.0260 | No | ||
5 | CD86 | 1660 22601 | 1910 | 1.663 | -0.0201 | No | ||
6 | PIM2 | 5249 9564 9565 | 2296 | 1.182 | -0.0344 | No | ||
7 | E2F3 | 21500 8874 | 2367 | 1.098 | -0.0321 | No | ||
8 | TSGA14 | 17194 | 2465 | 1.013 | -0.0318 | No | ||
9 | NR1D1 | 4650 20258 949 | 2687 | 0.830 | -0.0391 | No | ||
10 | TBR1 | 83 | 2694 | 0.823 | -0.0349 | No | ||
11 | HIST2H2AC | 6650 | 2842 | 0.685 | -0.0390 | No | ||
12 | IFIT2 | 23880 | 2977 | 0.572 | -0.0431 | No | ||
13 | NR6A1 | 14596 | 3015 | 0.547 | -0.0421 | No | ||
14 | ATF7IP | 12028 13038 | 3369 | 0.363 | -0.0592 | No | ||
15 | TWIST1 | 21291 | 3381 | 0.360 | -0.0578 | No | ||
16 | EAF2 | 1727 8383 | 3558 | 0.311 | -0.0656 | No | ||
17 | UBE2S | 17979 | 3627 | 0.293 | -0.0677 | No | ||
18 | SRF | 22961 1597 | 3826 | 0.245 | -0.0771 | No | ||
19 | TMOD2 | 6946 | 3837 | 0.243 | -0.0762 | No | ||
20 | BCDO2 | 19124 | 3862 | 0.238 | -0.0762 | No | ||
21 | CDH13 | 4506 3826 | 4231 | 0.181 | -0.0952 | No | ||
22 | LRRTM4 | 17405 | 4236 | 0.181 | -0.0944 | No | ||
23 | OLIG3 | 20084 | 4338 | 0.168 | -0.0989 | No | ||
24 | SFRP2 | 15564 | 4360 | 0.164 | -0.0992 | No | ||
25 | COL25A1 | 8056 1837 1844 1915 13376 | 4366 | 0.164 | -0.0985 | No | ||
26 | BCL2 | 8651 3928 13864 4435 981 4062 13863 4027 | 4380 | 0.162 | -0.0983 | No | ||
27 | FES | 17779 3949 | 4400 | 0.160 | -0.0985 | No | ||
28 | PTHLH | 16931 | 4462 | 0.154 | -0.1009 | No | ||
29 | VSNL1 | 6527 | 4603 | 0.141 | -0.1077 | No | ||
30 | POU3F4 | 347 | 4618 | 0.139 | -0.1077 | No | ||
31 | SCOC | 3821 12106 | 4641 | 0.137 | -0.1081 | No | ||
32 | HOXA10 | 17145 989 | 4672 | 0.135 | -0.1090 | No | ||
33 | SOX2 | 9849 15612 | 4683 | 0.134 | -0.1088 | No | ||
34 | DLGAP4 | 2950 10461 | 4708 | 0.132 | -0.1094 | No | ||
35 | LHX6 | 9275 2914 | 5003 | 0.112 | -0.1247 | No | ||
36 | MGAT5B | 20584 11197 | 5056 | 0.109 | -0.1269 | No | ||
37 | HOXA13 | 9107 | 5070 | 0.109 | -0.1270 | No | ||
38 | LRCH4 | 10544 6090 | 5115 | 0.106 | -0.1288 | No | ||
39 | CDX2 | 16289 | 5116 | 0.106 | -0.1282 | No | ||
40 | THRA | 1447 10171 1406 | 5121 | 0.106 | -0.1279 | No | ||
41 | WNT6 | 5881 | 5277 | 0.097 | -0.1357 | No | ||
42 | TCF2 | 1395 20727 | 5292 | 0.096 | -0.1360 | No | ||
43 | NEUROD6 | 17138 | 5317 | 0.095 | -0.1367 | No | ||
44 | CDX4 | 24273 | 5718 | 0.076 | -0.1580 | No | ||
45 | CPD | 20344 4556 | 5726 | 0.076 | -0.1580 | No | ||
46 | MID1 | 5097 5098 | 5763 | 0.074 | -0.1595 | No | ||
47 | BDNF | 14926 2797 | 5766 | 0.074 | -0.1592 | No | ||
48 | RGL1 | 9723 4072 | 5894 | 0.070 | -0.1657 | No | ||
49 | SLC19A3 | 8152 | 5896 | 0.070 | -0.1654 | No | ||
50 | HOXB6 | 20688 | 6001 | 0.067 | -0.1707 | No | ||
51 | NRL | 9484 | 6218 | 0.060 | -0.1820 | No | ||
52 | RRM2B | 6902 6903 11801 | 6260 | 0.059 | -0.1839 | No | ||
53 | ALDH1A1 | 8569 | 6352 | 0.057 | -0.1886 | No | ||
54 | CRYZL1 | 1644 12385 | 6364 | 0.056 | -0.1888 | No | ||
55 | DNAH5 | 8470 | 6451 | 0.054 | -0.1932 | No | ||
56 | CYR61 | 9159 15145 9311 5024 | 6695 | 0.049 | -0.2061 | No | ||
57 | NRAS | 5191 | 6779 | 0.047 | -0.2104 | No | ||
58 | IRX4 | 11944 | 6813 | 0.046 | -0.2119 | No | ||
59 | KLF12 | 4960 2637 21732 9228 | 7086 | 0.040 | -0.2264 | No | ||
60 | SILV | 16130 | 7151 | 0.039 | -0.2297 | No | ||
61 | SLC1A2 | 5453 | 7238 | 0.038 | -0.2341 | No | ||
62 | PCYT1B | 24289 | 7396 | 0.035 | -0.2425 | No | ||
63 | LPL | 9283 5003 | 7564 | 0.032 | -0.2513 | No | ||
64 | STAG1 | 5520 9905 2987 | 7660 | 0.030 | -0.2563 | No | ||
65 | EPHB3 | 22816 | 8008 | 0.025 | -0.2750 | No | ||
66 | FBXO24 | 12918 3649 | 8108 | 0.023 | -0.2803 | No | ||
67 | PCDH20 | 5780 | 8316 | 0.020 | -0.2914 | No | ||
68 | LIPG | 23407 | 8382 | 0.019 | -0.2948 | No | ||
69 | FSTL5 | 10018 | 8526 | 0.017 | -0.3025 | No | ||
70 | MBIP | 21063 2072 | 8582 | 0.017 | -0.3054 | No | ||
71 | PRKG1 | 5289 | 8606 | 0.016 | -0.3065 | No | ||
72 | ITSN1 | 9196 | 8676 | 0.015 | -0.3102 | No | ||
73 | TBXAS1 | 17480 1105 | 8698 | 0.015 | -0.3112 | No | ||
74 | ALK | 8574 | 8962 | 0.012 | -0.3254 | No | ||
75 | FGF14 | 21716 3005 3463 | 9073 | 0.011 | -0.3313 | No | ||
76 | NRXN3 | 2153 5196 | 9166 | 0.010 | -0.3363 | No | ||
77 | FGF12 | 1723 22621 | 9206 | 0.009 | -0.3383 | No | ||
78 | SLC6A15 | 8335 3321 | 9209 | 0.009 | -0.3384 | No | ||
79 | PAX6 | 5223 | 9241 | 0.009 | -0.3400 | No | ||
80 | PRRX1 | 9595 5271 | 9264 | 0.008 | -0.3412 | No | ||
81 | ADORA2A | 8557 | 9558 | 0.004 | -0.3571 | No | ||
82 | GNB3 | 9027 | 9671 | 0.003 | -0.3631 | No | ||
83 | NXPH1 | 17524 | 9695 | 0.003 | -0.3644 | No | ||
84 | UPK3A | 22401 | 9731 | 0.002 | -0.3662 | No | ||
85 | TSC1 | 7235 | 9972 | -0.001 | -0.3793 | No | ||
86 | PRDM1 | 19775 3337 | 9987 | -0.001 | -0.3800 | No | ||
87 | NFIA | 16172 5170 | 10033 | -0.002 | -0.3824 | No | ||
88 | SYNPR | 22094 | 10206 | -0.003 | -0.3918 | No | ||
89 | LYN | 16281 | 10463 | -0.007 | -0.4056 | No | ||
90 | EHF | 4657 | 10541 | -0.008 | -0.4097 | No | ||
91 | RGS13 | 13811 | 10617 | -0.009 | -0.4138 | No | ||
92 | CNNM4 | 14273 | 10721 | -0.010 | -0.4193 | No | ||
93 | TCEAL1 | 24245 | 11044 | -0.015 | -0.4367 | No | ||
94 | SKIL | 15617 | 11169 | -0.017 | -0.4433 | No | ||
95 | SLC24A1 | 19080 | 11192 | -0.017 | -0.4444 | No | ||
96 | MRAS | 9409 | 11204 | -0.017 | -0.4449 | No | ||
97 | HOXC5 | 22340 | 11404 | -0.020 | -0.4556 | No | ||
98 | MITF | 17349 | 11903 | -0.028 | -0.4825 | No | ||
99 | CSF3 | 1394 20671 | 11910 | -0.028 | -0.4826 | No | ||
100 | GPR4 | 18364 | 12216 | -0.034 | -0.4990 | No | ||
101 | SATB2 | 5604 | 12242 | -0.035 | -0.5002 | No | ||
102 | KIF13A | 21475 | 12291 | -0.036 | -0.5026 | No | ||
103 | GPC4 | 24153 | 12457 | -0.040 | -0.5113 | No | ||
104 | POU2F3 | 9602 | 12488 | -0.041 | -0.5127 | No | ||
105 | CLCA3 | 6224 | 12492 | -0.041 | -0.5126 | No | ||
106 | CRISP1 | 22980 | 12500 | -0.041 | -0.5128 | No | ||
107 | SPRR2B | 9869 | 12547 | -0.043 | -0.5150 | No | ||
108 | GAB2 | 1821 18184 2025 | 12548 | -0.043 | -0.5148 | No | ||
109 | OTX2 | 9519 | 12559 | -0.043 | -0.5151 | No | ||
110 | SH3GL3 | 18201 | 12587 | -0.044 | -0.5163 | No | ||
111 | GUCA1A | 22952 | 12662 | -0.046 | -0.5201 | No | ||
112 | NRXN1 | 1581 1575 22875 | 12682 | -0.046 | -0.5209 | No | ||
113 | DPYSL3 | 10252 | 12753 | -0.048 | -0.5244 | No | ||
114 | LDB2 | 16538 4989 | 12850 | -0.050 | -0.5293 | No | ||
115 | HIST1H2AC | 6648 | 13181 | -0.060 | -0.5469 | No | ||
116 | LRRN1 | 17343 | 13353 | -0.067 | -0.5558 | No | ||
117 | SLITRK6 | 21724 | 13367 | -0.067 | -0.5561 | No | ||
118 | HPCAL4 | 16096 | 13476 | -0.072 | -0.5616 | No | ||
119 | KCTD6 | 22098 | 13481 | -0.072 | -0.5614 | No | ||
120 | CSMD3 | 10735 7938 | 13547 | -0.075 | -0.5645 | No | ||
121 | ASCL3 | 17681 | 13563 | -0.077 | -0.5649 | No | ||
122 | ADORA1 | 13831 | 13775 | -0.088 | -0.5759 | No | ||
123 | SP6 | 8178 13678 13679 | 13869 | -0.093 | -0.5804 | No | ||
124 | PIPOX | 20340 | 14001 | -0.102 | -0.5869 | No | ||
125 | PFKFB1 | 9552 | 14062 | -0.107 | -0.5896 | No | ||
126 | TLL2 | 23680 | 14287 | -0.128 | -0.6010 | No | ||
127 | NEUROG1 | 21446 | 14383 | -0.139 | -0.6054 | No | ||
128 | COL23A1 | 10696 | 14387 | -0.139 | -0.6048 | No | ||
129 | GPRC5B | 17662 | 14414 | -0.142 | -0.6054 | No | ||
130 | RAB26 | 11609 | 14453 | -0.146 | -0.6067 | No | ||
131 | KCNN3 | 15538 1913 | 14519 | -0.153 | -0.6093 | No | ||
132 | DMD | 24295 2647 | 14621 | -0.170 | -0.6139 | No | ||
133 | TRPM1 | 10846 474 9395 494 | 14718 | -0.187 | -0.6181 | No | ||
134 | GPM6A | 3834 10618 | 14806 | -0.202 | -0.6216 | No | ||
135 | FZD2 | 12179 | 14970 | -0.234 | -0.6292 | No | ||
136 | STAT4 | 14251 9907 | 15027 | -0.245 | -0.6309 | No | ||
137 | NR2C2 | 10216 | 15085 | -0.260 | -0.6325 | No | ||
138 | ETV1 | 4688 8925 8924 | 15473 | -0.378 | -0.6514 | No | ||
139 | HDAC9 | 21084 2131 | 15556 | -0.425 | -0.6535 | No | ||
140 | SESN3 | 19561 | 15821 | -0.567 | -0.6647 | No | ||
141 | PDE4D | 10722 6235 | 15934 | -0.668 | -0.6670 | No | ||
142 | EGR2 | 8886 | 16006 | -0.728 | -0.6668 | No | ||
143 | REL | 9716 | 16182 | -0.909 | -0.6713 | Yes | ||
144 | NEDD4 | 19384 3101 | 16197 | -0.925 | -0.6669 | Yes | ||
145 | SREBF2 | 5509 | 16231 | -0.963 | -0.6633 | Yes | ||
146 | HIST1H2BC | 12625 21696 | 16275 | -0.995 | -0.6601 | Yes | ||
147 | BAT2 | 23006 | 16430 | -1.134 | -0.6621 | Yes | ||
148 | NDNL2 | 17804 | 16432 | -1.135 | -0.6559 | Yes | ||
149 | HIST1H2AH | 11414 | 16447 | -1.152 | -0.6502 | Yes | ||
150 | PIK3CD | 9563 | 16730 | -1.548 | -0.6569 | Yes | ||
151 | HIST1H3C | 13633 | 16785 | -1.644 | -0.6507 | Yes | ||
152 | BIN3 | 21969 | 16811 | -1.682 | -0.6427 | Yes | ||
153 | ARPC5 | 12580 7487 | 16854 | -1.726 | -0.6353 | Yes | ||
154 | GFI1B | 14637 | 16881 | -1.743 | -0.6270 | Yes | ||
155 | ITPR3 | 9195 | 16893 | -1.758 | -0.6179 | Yes | ||
156 | POLM | 20538 | 16947 | -1.829 | -0.6105 | Yes | ||
157 | H3F3B | 4839 | 17030 | -1.944 | -0.6042 | Yes | ||
158 | KCTD12 | 6240 | 17076 | -2.022 | -0.5954 | Yes | ||
159 | MAP2K6 | 20614 1414 | 17087 | -2.043 | -0.5845 | Yes | ||
160 | SLC25A12 | 14562 | 17171 | -2.189 | -0.5768 | Yes | ||
161 | CSNK1E | 6570 2211 11332 | 17205 | -2.253 | -0.5661 | Yes | ||
162 | HIST1H2AB | 13652 | 17210 | -2.260 | -0.5537 | Yes | ||
163 | RHOB | 4411 | 17229 | -2.286 | -0.5420 | Yes | ||
164 | HIST1H2BB | 11417 | 17363 | -2.580 | -0.5348 | Yes | ||
165 | SH3BGRL | 24267 | 17437 | -2.706 | -0.5237 | Yes | ||
166 | CD79B | 20185 1309 | 17530 | -2.928 | -0.5124 | Yes | ||
167 | ZHX2 | 11842 | 17581 | -3.041 | -0.4982 | Yes | ||
168 | HIST1H2BM | 11425 | 17636 | -3.198 | -0.4833 | Yes | ||
169 | HIST1H2BK | 11423 | 17694 | -3.349 | -0.4678 | Yes | ||
170 | THRAP5 | 19701 | 17763 | -3.526 | -0.4518 | Yes | ||
171 | NFYB | 5173 | 17805 | -3.631 | -0.4338 | Yes | ||
172 | AXUD1 | 18967 | 17830 | -3.686 | -0.4146 | Yes | ||
173 | BTK | 24061 | 17851 | -3.733 | -0.3949 | Yes | ||
174 | SCML4 | 20042 | 17854 | -3.739 | -0.3742 | Yes | ||
175 | ESRRA | 23802 | 18014 | -4.270 | -0.3591 | Yes | ||
176 | HIST1H3B | 11406 | 18056 | -4.487 | -0.3363 | Yes | ||
177 | TCF12 | 10044 3125 | 18082 | -4.573 | -0.3122 | Yes | ||
178 | HIST2H2BE | 6651 | 18133 | -4.739 | -0.2886 | Yes | ||
179 | RRAS | 18256 | 18165 | -4.858 | -0.2632 | Yes | ||
180 | NOTCH1 | 14649 | 18176 | -4.903 | -0.2364 | Yes | ||
181 | PTEN | 5305 | 18200 | -4.996 | -0.2099 | Yes | ||
182 | FOXP1 | 4242 | 18274 | -5.385 | -0.1839 | Yes | ||
183 | ARHGAP4 | 9343 | 18368 | -5.919 | -0.1559 | Yes | ||
184 | VPREB3 | 19984 | 18430 | -6.427 | -0.1235 | Yes | ||
185 | ACBD4 | 20637 | 18468 | -6.970 | -0.0867 | Yes | ||
186 | RHOBTB2 | 3069 6373 10902 | 18507 | -7.411 | -0.0475 | Yes | ||
187 | DUSP6 | 19891 3399 | 18608 | -9.583 | 0.0004 | Yes |