Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | DMpreB |
GeneSet | V$E2F_Q6 |
Enrichment Score (ES) | 0.54243714 |
Normalized Enrichment Score (NES) | 1.349774 |
Nominal p-value | 0.011925043 |
FDR q-value | 0.40591472 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SNRPD1 | 23622 | 185 | 7.175 | 0.0204 | Yes | ||
2 | MSH2 | 23138 | 212 | 6.910 | 0.0482 | Yes | ||
3 | NASP | 2383 2387 6955 | 263 | 6.510 | 0.0731 | Yes | ||
4 | CDCA7 | 12437 | 293 | 6.274 | 0.0981 | Yes | ||
5 | KPNB1 | 20274 | 306 | 6.181 | 0.1236 | Yes | ||
6 | UNG | 10257 16744 | 315 | 6.124 | 0.1491 | Yes | ||
7 | NOLC1 | 7704 | 329 | 5.999 | 0.1738 | Yes | ||
8 | FANCD2 | 17326 464 | 350 | 5.936 | 0.1979 | Yes | ||
9 | MCM3 | 13991 | 390 | 5.583 | 0.2194 | Yes | ||
10 | DNMT1 | 19217 | 456 | 5.277 | 0.2382 | Yes | ||
11 | RQCD1 | 12205 | 475 | 5.201 | 0.2593 | Yes | ||
12 | MCM7 | 9372 3568 | 497 | 5.089 | 0.2797 | Yes | ||
13 | MCM2 | 17074 | 598 | 4.627 | 0.2939 | Yes | ||
14 | CDC25A | 8721 | 631 | 4.494 | 0.3112 | Yes | ||
15 | GSPT1 | 9046 | 684 | 4.328 | 0.3267 | Yes | ||
16 | MRPL40 | 22641 | 728 | 4.188 | 0.3421 | Yes | ||
17 | POLA2 | 23988 | 733 | 4.174 | 0.3596 | Yes | ||
18 | PHF5A | 22194 | 738 | 4.141 | 0.3769 | Yes | ||
19 | ACBD6 | 14089 | 743 | 4.124 | 0.3941 | Yes | ||
20 | PRPS1 | 24233 | 804 | 3.939 | 0.4076 | Yes | ||
21 | NCL | 5153 13899 | 818 | 3.882 | 0.4233 | Yes | ||
22 | GMNN | 21513 | 848 | 3.827 | 0.4379 | Yes | ||
23 | ACO2 | 8527 | 968 | 3.418 | 0.4460 | Yes | ||
24 | SMAD6 | 19083 | 1038 | 3.214 | 0.4558 | Yes | ||
25 | PCNA | 9535 | 1100 | 3.074 | 0.4656 | Yes | ||
26 | PPP1R8 | 15730 | 1138 | 2.994 | 0.4762 | Yes | ||
27 | HIRA | 4852 9090 | 1204 | 2.854 | 0.4848 | Yes | ||
28 | CDT1 | 18437 | 1380 | 2.457 | 0.4857 | Yes | ||
29 | NUP62 | 9497 | 1445 | 2.341 | 0.4922 | Yes | ||
30 | SUMO1 | 5826 3943 10247 | 1636 | 2.077 | 0.4907 | Yes | ||
31 | INSM1 | 14815 | 1670 | 2.029 | 0.4975 | Yes | ||
32 | EED | 17759 | 1687 | 1.998 | 0.5051 | Yes | ||
33 | HTF9C | 4886 1678 | 1702 | 1.969 | 0.5127 | Yes | ||
34 | ILF3 | 3110 3030 9176 | 1753 | 1.884 | 0.5179 | Yes | ||
35 | RRM2 | 5401 5400 | 1791 | 1.841 | 0.5237 | Yes | ||
36 | STMN1 | 9261 | 1819 | 1.798 | 0.5299 | Yes | ||
37 | POLD3 | 17742 | 1845 | 1.754 | 0.5359 | Yes | ||
38 | DNAJC11 | 2486 6068 | 1924 | 1.635 | 0.5386 | Yes | ||
39 | SFRS1 | 8492 | 2072 | 1.466 | 0.5369 | Yes | ||
40 | USP37 | 13923 | 2107 | 1.433 | 0.5411 | Yes | ||
41 | E2F3 | 21500 8874 | 2367 | 1.098 | 0.5317 | Yes | ||
42 | PHF13 | 15659 | 2372 | 1.093 | 0.5362 | Yes | ||
43 | SFRS7 | 22889 | 2416 | 1.053 | 0.5383 | Yes | ||
44 | CLSPN | 16079 11256 6530 | 2461 | 1.017 | 0.5402 | Yes | ||
45 | UXT | 5837 10267 | 2499 | 0.999 | 0.5424 | Yes | ||
46 | POLR2A | 5394 | 2654 | 0.858 | 0.5377 | No | ||
47 | SFRS2 | 9807 20136 | 2789 | 0.733 | 0.5336 | No | ||
48 | PAQR4 | 23105 | 3014 | 0.549 | 0.5238 | No | ||
49 | ARID4A | 2080 6215 | 3041 | 0.533 | 0.5246 | No | ||
50 | E2F7 | 19884 | 3187 | 0.447 | 0.5187 | No | ||
51 | WEE1 | 18127 | 3229 | 0.429 | 0.5183 | No | ||
52 | YBX2 | 20818 | 3538 | 0.316 | 0.5029 | No | ||
53 | HOXC10 | 22342 | 3555 | 0.312 | 0.5034 | No | ||
54 | KCND2 | 4941 17515 | 3623 | 0.295 | 0.5010 | No | ||
55 | RAD51 | 2897 14903 | 3710 | 0.271 | 0.4975 | No | ||
56 | PHC1 | 17013 | 3963 | 0.220 | 0.4848 | No | ||
57 | SLC38A1 | 22148 | 3975 | 0.218 | 0.4851 | No | ||
58 | MCM4 | 22655 1708 | 4196 | 0.186 | 0.4740 | No | ||
59 | ASXL2 | 7957 | 4207 | 0.184 | 0.4742 | No | ||
60 | SYNGR4 | 17825 | 4350 | 0.166 | 0.4672 | No | ||
61 | E2F1 | 14384 | 4565 | 0.144 | 0.4562 | No | ||
62 | SEMA6A | 23439 9802 | 4940 | 0.116 | 0.4365 | No | ||
63 | TREX2 | 24137 | 5519 | 0.085 | 0.4055 | No | ||
64 | PHF15 | 20467 8050 | 5571 | 0.083 | 0.4031 | No | ||
65 | RANBP1 | 9692 5357 | 5854 | 0.071 | 0.3882 | No | ||
66 | GRIA4 | 19249 | 5979 | 0.067 | 0.3817 | No | ||
67 | ZBTB4 | 13267 | 6030 | 0.066 | 0.3793 | No | ||
68 | CDC6 | 6221 6220 | 6125 | 0.063 | 0.3745 | No | ||
69 | PODN | 15811 | 6202 | 0.060 | 0.3706 | No | ||
70 | HNRPUL1 | 6118 17923 1608 10577 1345 | 6262 | 0.059 | 0.3677 | No | ||
71 | RBL1 | 14373 | 6291 | 0.058 | 0.3664 | No | ||
72 | PRKDC | 9617 22847 | 6336 | 0.057 | 0.3642 | No | ||
73 | SEMA5A | 22496 5423 | 6492 | 0.053 | 0.3561 | No | ||
74 | TYRO3 | 5811 | 6547 | 0.052 | 0.3534 | No | ||
75 | ATAD2 | 2268 2256 | 6586 | 0.051 | 0.3515 | No | ||
76 | SLC6A4 | 20770 | 6749 | 0.047 | 0.3430 | No | ||
77 | EPHB1 | 19024 | 6869 | 0.045 | 0.3367 | No | ||
78 | UFD1L | 22825 | 7359 | 0.035 | 0.3104 | No | ||
79 | PCSK1 | 21600 | 7368 | 0.035 | 0.3101 | No | ||
80 | HNRPD | 8645 | 7481 | 0.033 | 0.3042 | No | ||
81 | FBXO5 | 19830 | 7525 | 0.032 | 0.3020 | No | ||
82 | STAG1 | 5520 9905 2987 | 7660 | 0.030 | 0.2948 | No | ||
83 | MYH10 | 8077 | 7788 | 0.028 | 0.2881 | No | ||
84 | PRPF4B | 3208 5295 | 7901 | 0.026 | 0.2821 | No | ||
85 | SFRS10 | 9818 1722 5441 | 8002 | 0.025 | 0.2768 | No | ||
86 | TBX6 | 1993 18075 | 8478 | 0.018 | 0.2512 | No | ||
87 | STK35 | 14851 | 8658 | 0.016 | 0.2415 | No | ||
88 | MAZ | 1327 17623 | 8787 | 0.014 | 0.2347 | No | ||
89 | ADAMTS2 | 5706 20899 1356 | 9005 | 0.012 | 0.2230 | No | ||
90 | PAX6 | 5223 | 9241 | 0.009 | 0.2103 | No | ||
91 | HS6ST3 | 21933 | 9385 | 0.007 | 0.2026 | No | ||
92 | TOPBP1 | 10659 | 9405 | 0.006 | 0.2016 | No | ||
93 | NUP153 | 21474 | 9407 | 0.006 | 0.2015 | No | ||
94 | CDC45L | 22642 1752 | 9951 | -0.001 | 0.1721 | No | ||
95 | HCN3 | 4843 1763 | 10154 | -0.003 | 0.1612 | No | ||
96 | SP3 | 5483 | 10159 | -0.003 | 0.1610 | No | ||
97 | CASP8AP2 | 16253 | 10367 | -0.005 | 0.1498 | No | ||
98 | SLCO3A1 | 17796 4237 8430 | 10399 | -0.006 | 0.1482 | No | ||
99 | GABRB3 | 4747 | 10880 | -0.012 | 0.1222 | No | ||
100 | POLE2 | 21053 | 10899 | -0.013 | 0.1213 | No | ||
101 | IPO7 | 6130 | 11087 | -0.015 | 0.1112 | No | ||
102 | EZH2 | 1092 17163 | 11493 | -0.021 | 0.0894 | No | ||
103 | FMO4 | 13786 | 11581 | -0.023 | 0.0848 | No | ||
104 | DNAJC9 | 21912 | 12010 | -0.030 | 0.0617 | No | ||
105 | NRP2 | 5194 9486 5195 | 12343 | -0.038 | 0.0439 | No | ||
106 | RHD | 16042 | 12393 | -0.039 | 0.0414 | No | ||
107 | CBX5 | 22108 4485 | 12505 | -0.041 | 0.0356 | No | ||
108 | PVRL1 | 3006 19482 12211 7192 | 12855 | -0.050 | 0.0169 | No | ||
109 | TMPO | 5778 | 13368 | -0.067 | -0.0106 | No | ||
110 | NELL2 | 12006 7020 22151 | 13383 | -0.068 | -0.0110 | No | ||
111 | RPS6KA5 | 2076 21005 | 13512 | -0.073 | -0.0176 | No | ||
112 | JPH1 | 13994 | 13674 | -0.082 | -0.0260 | No | ||
113 | MCM8 | 14834 | 13711 | -0.084 | -0.0276 | No | ||
114 | ARHGAP6 | 24207 | 13898 | -0.095 | -0.0373 | No | ||
115 | KCNA6 | 664 16990 665 4938 | 13927 | -0.097 | -0.0384 | No | ||
116 | H2AFZ | 6957 | 14069 | -0.108 | -0.0456 | No | ||
117 | EFNA5 | 4655 8884 | 14410 | -0.142 | -0.0634 | No | ||
118 | GPRC5B | 17662 | 14414 | -0.142 | -0.0629 | No | ||
119 | DDB2 | 2721 2878 14525 2661 | 14421 | -0.143 | -0.0627 | No | ||
120 | DMD | 24295 2647 | 14621 | -0.170 | -0.0727 | No | ||
121 | AP4M1 | 3499 16656 | 14702 | -0.183 | -0.0763 | No | ||
122 | ERBB2IP | 3232 12234 | 14739 | -0.190 | -0.0774 | No | ||
123 | PPP1CC | 9609 5283 | 14815 | -0.203 | -0.0806 | No | ||
124 | HMGN2 | 9095 | 15229 | -0.297 | -0.1017 | No | ||
125 | ZCCHC8 | 3570 7696 | 15368 | -0.339 | -0.1078 | No | ||
126 | HNRPR | 13196 7909 2500 | 15460 | -0.375 | -0.1111 | No | ||
127 | ATF5 | 17843 | 15505 | -0.396 | -0.1118 | No | ||
128 | UGCGL1 | 6721 | 15672 | -0.475 | -0.1188 | No | ||
129 | CORT | 15669 2539 | 15707 | -0.497 | -0.1185 | No | ||
130 | MCM6 | 4000 13845 4119 | 15865 | -0.608 | -0.1245 | No | ||
131 | STAG2 | 5521 | 16122 | -0.850 | -0.1347 | No | ||
132 | BRMS1L | 21268 | 16232 | -0.966 | -0.1365 | No | ||
133 | HNRPA1 | 9103 4860 | 16286 | -0.999 | -0.1352 | No | ||
134 | CCNT1 | 22140 11607 | 16429 | -1.133 | -0.1381 | No | ||
135 | HIST1H2AH | 11414 | 16447 | -1.152 | -0.1341 | No | ||
136 | ING3 | 17514 1019 | 16667 | -1.449 | -0.1398 | No | ||
137 | FHOD1 | 18772 | 16792 | -1.656 | -0.1395 | No | ||
138 | ALDH6A1 | 21025 | 16891 | -1.754 | -0.1374 | No | ||
139 | USP52 | 3397 19841 | 16964 | -1.853 | -0.1335 | No | ||
140 | POLE4 | 12441 | 17259 | -2.349 | -0.1394 | No | ||
141 | CTCF | 18490 | 17307 | -2.434 | -0.1317 | No | ||
142 | POLD1 | 17847 | 17439 | -2.709 | -0.1273 | No | ||
143 | PIM1 | 23308 | 17500 | -2.869 | -0.1184 | No | ||
144 | HIST1H2BK | 11423 | 17694 | -3.349 | -0.1147 | No | ||
145 | HIST1H4A | 11590 | 17700 | -3.358 | -0.1007 | No | ||
146 | AK2 | 8563 2479 16073 | 17761 | -3.520 | -0.0891 | No | ||
147 | SOAT1 | 13797 | 17882 | -3.831 | -0.0793 | No | ||
148 | DCK | 16808 | 17923 | -3.959 | -0.0647 | No | ||
149 | PPM1D | 20721 | 18053 | -4.474 | -0.0528 | No | ||
150 | RAB11B | 9676 | 18106 | -4.643 | -0.0359 | No | ||
151 | MXD3 | 21455 | 18295 | -5.505 | -0.0228 | No | ||
152 | IL4I1 | 8971 | 18606 | -9.474 | 0.0005 | No |