Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | DMpreB |
GeneSet | V$E2F_Q4_01 |
Enrichment Score (ES) | 0.5695536 |
Normalized Enrichment Score (NES) | 1.4271429 |
Nominal p-value | 0.0033557047 |
FDR q-value | 0.550277 |
FWER p-Value | 0.993 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | IMPDH2 | 10730 | 85 | 8.592 | 0.0308 | Yes | ||
2 | PPRC1 | 23808 | 151 | 7.606 | 0.0586 | Yes | ||
3 | EIF5A | 11345 20379 6590 | 188 | 7.145 | 0.0860 | Yes | ||
4 | NASP | 2383 2387 6955 | 263 | 6.510 | 0.1088 | Yes | ||
5 | CDCA7 | 12437 | 293 | 6.274 | 0.1331 | Yes | ||
6 | KPNB1 | 20274 | 306 | 6.181 | 0.1579 | Yes | ||
7 | UNG | 10257 16744 | 315 | 6.124 | 0.1827 | Yes | ||
8 | RFC1 | 16527 | 335 | 5.989 | 0.2063 | Yes | ||
9 | MCM3 | 13991 | 390 | 5.583 | 0.2263 | Yes | ||
10 | IPO11 | 21353 | 445 | 5.329 | 0.2454 | Yes | ||
11 | DNMT1 | 19217 | 456 | 5.277 | 0.2665 | Yes | ||
12 | MCM7 | 9372 3568 | 497 | 5.089 | 0.2853 | Yes | ||
13 | ATP5G2 | 12610 | 588 | 4.682 | 0.2997 | Yes | ||
14 | MCM2 | 17074 | 598 | 4.627 | 0.3183 | Yes | ||
15 | CDC25A | 8721 | 631 | 4.494 | 0.3351 | Yes | ||
16 | KNTC1 | 16705 | 725 | 4.189 | 0.3473 | Yes | ||
17 | POLA2 | 23988 | 733 | 4.174 | 0.3641 | Yes | ||
18 | NUTF2 | 12632 7529 | 734 | 4.174 | 0.3813 | Yes | ||
19 | ACBD6 | 14089 | 743 | 4.124 | 0.3978 | Yes | ||
20 | NCL | 5153 13899 | 818 | 3.882 | 0.4098 | Yes | ||
21 | GMNN | 21513 | 848 | 3.827 | 0.4240 | Yes | ||
22 | HMGA1 | 23323 | 1003 | 3.313 | 0.4293 | Yes | ||
23 | SYT11 | 15285 | 1044 | 3.199 | 0.4403 | Yes | ||
24 | APRIN | 4145 | 1045 | 3.198 | 0.4534 | Yes | ||
25 | TIAM1 | 22547 | 1097 | 3.076 | 0.4633 | Yes | ||
26 | PCNA | 9535 | 1100 | 3.074 | 0.4759 | Yes | ||
27 | RPS19 | 5398 | 1114 | 3.041 | 0.4877 | Yes | ||
28 | PPP1R8 | 15730 | 1138 | 2.994 | 0.4988 | Yes | ||
29 | PRIM1 | 19847 | 1169 | 2.930 | 0.5092 | Yes | ||
30 | SUV39H1 | 24194 | 1202 | 2.857 | 0.5192 | Yes | ||
31 | PIK3R3 | 5248 | 1211 | 2.839 | 0.5305 | Yes | ||
32 | UCHL1 | 16834 | 1369 | 2.481 | 0.5322 | Yes | ||
33 | MELK | 2453 16227 | 1495 | 2.254 | 0.5347 | Yes | ||
34 | FANCC | 4712 | 1556 | 2.184 | 0.5405 | Yes | ||
35 | HTF9C | 4886 1678 | 1702 | 1.969 | 0.5407 | Yes | ||
36 | DLST | 8131 | 1734 | 1.908 | 0.5469 | Yes | ||
37 | STMN1 | 9261 | 1819 | 1.798 | 0.5497 | Yes | ||
38 | PIK3R4 | 19333 | 1855 | 1.740 | 0.5550 | Yes | ||
39 | YWHAQ | 10369 | 1863 | 1.733 | 0.5618 | Yes | ||
40 | DNAJC11 | 2486 6068 | 1924 | 1.635 | 0.5652 | Yes | ||
41 | RBBP4 | 5364 | 2042 | 1.502 | 0.5651 | Yes | ||
42 | SFRS1 | 8492 | 2072 | 1.466 | 0.5696 | Yes | ||
43 | E2F3 | 21500 8874 | 2367 | 1.098 | 0.5581 | No | ||
44 | UXT | 5837 10267 | 2499 | 0.999 | 0.5552 | No | ||
45 | SFRS2 | 9807 20136 | 2789 | 0.733 | 0.5425 | No | ||
46 | DAXX | 23290 | 2992 | 0.562 | 0.5339 | No | ||
47 | PAQR4 | 23105 | 3014 | 0.549 | 0.5350 | No | ||
48 | ARID4A | 2080 6215 | 3041 | 0.533 | 0.5358 | No | ||
49 | SFMBT1 | 12053 7050 | 3044 | 0.531 | 0.5379 | No | ||
50 | NCOA6 | 2876 14382 | 3151 | 0.461 | 0.5340 | No | ||
51 | E2F7 | 19884 | 3187 | 0.447 | 0.5340 | No | ||
52 | CASP2 | 8692 | 3192 | 0.445 | 0.5356 | No | ||
53 | WEE1 | 18127 | 3229 | 0.429 | 0.5354 | No | ||
54 | TNPO2 | 5608 | 3375 | 0.362 | 0.5290 | No | ||
55 | YBX2 | 20818 | 3538 | 0.316 | 0.5216 | No | ||
56 | HOXC10 | 22342 | 3555 | 0.312 | 0.5220 | No | ||
57 | KCND2 | 4941 17515 | 3623 | 0.295 | 0.5196 | No | ||
58 | RAD51 | 2897 14903 | 3710 | 0.271 | 0.5160 | No | ||
59 | SLC38A1 | 22148 | 3975 | 0.218 | 0.5026 | No | ||
60 | MCM4 | 22655 1708 | 4196 | 0.186 | 0.4915 | No | ||
61 | ASXL2 | 7957 | 4207 | 0.184 | 0.4917 | No | ||
62 | E2F1 | 14384 | 4565 | 0.144 | 0.4729 | No | ||
63 | HOXA9 | 17147 9109 1024 | 4614 | 0.139 | 0.4709 | No | ||
64 | TOP1 | 5790 5789 10210 | 4715 | 0.132 | 0.4660 | No | ||
65 | NEGR1 | 6806 11572 | 4984 | 0.113 | 0.4520 | No | ||
66 | MAP3K13 | 22814 | 5223 | 0.100 | 0.4395 | No | ||
67 | PHF15 | 20467 8050 | 5571 | 0.083 | 0.4210 | No | ||
68 | RANBP1 | 9692 5357 | 5854 | 0.071 | 0.4061 | No | ||
69 | SLBP | 9822 | 5857 | 0.071 | 0.4062 | No | ||
70 | CDC6 | 6221 6220 | 6125 | 0.063 | 0.3920 | No | ||
71 | NR3C2 | 18562 13798 | 6127 | 0.063 | 0.3922 | No | ||
72 | SALL1 | 18796 12207 | 6190 | 0.061 | 0.3891 | No | ||
73 | PODN | 15811 | 6202 | 0.060 | 0.3888 | No | ||
74 | PRKDC | 9617 22847 | 6336 | 0.057 | 0.3818 | No | ||
75 | SEMA5A | 22496 5423 | 6492 | 0.053 | 0.3736 | No | ||
76 | ATAD2 | 2268 2256 | 6586 | 0.051 | 0.3688 | No | ||
77 | SLC6A4 | 20770 | 6749 | 0.047 | 0.3602 | No | ||
78 | EPHB1 | 19024 | 6869 | 0.045 | 0.3540 | No | ||
79 | DPYSL2 | 3122 4561 8787 | 6945 | 0.043 | 0.3501 | No | ||
80 | UFD1L | 22825 | 7359 | 0.035 | 0.3278 | No | ||
81 | GATA3 | 9004 | 7429 | 0.034 | 0.3242 | No | ||
82 | HNRPD | 8645 | 7481 | 0.033 | 0.3216 | No | ||
83 | PCDH7 | 7029 3460 | 7483 | 0.033 | 0.3217 | No | ||
84 | FBXO5 | 19830 | 7525 | 0.032 | 0.3196 | No | ||
85 | STAG1 | 5520 9905 2987 | 7660 | 0.030 | 0.3125 | No | ||
86 | HIST1H1D | 4821 | 7823 | 0.027 | 0.3038 | No | ||
87 | LUC7L2 | 5313 5312 | 8013 | 0.025 | 0.2937 | No | ||
88 | PLK4 | 1870 1874 | 8253 | 0.021 | 0.2808 | No | ||
89 | CITED2 | 5118 14477 | 8285 | 0.021 | 0.2792 | No | ||
90 | ERG | 1686 8915 | 8403 | 0.019 | 0.2730 | No | ||
91 | MAZ | 1327 17623 | 8787 | 0.014 | 0.2523 | No | ||
92 | ADAMTS2 | 5706 20899 1356 | 9005 | 0.012 | 0.2406 | No | ||
93 | GLRA3 | 18617 | 9309 | 0.008 | 0.2242 | No | ||
94 | TOPBP1 | 10659 | 9405 | 0.006 | 0.2191 | No | ||
95 | CDC45L | 22642 1752 | 9951 | -0.001 | 0.1895 | No | ||
96 | EPHB2 | 4675 2440 8910 | 10347 | -0.005 | 0.1681 | No | ||
97 | BAI1 | 22459 | 10352 | -0.005 | 0.1680 | No | ||
98 | CASP8AP2 | 16253 | 10367 | -0.005 | 0.1672 | No | ||
99 | USP2 | 19480 3052 3043 | 10584 | -0.008 | 0.1556 | No | ||
100 | POLE2 | 21053 | 10899 | -0.013 | 0.1386 | No | ||
101 | IPO7 | 6130 | 11087 | -0.015 | 0.1285 | No | ||
102 | EZH2 | 1092 17163 | 11493 | -0.021 | 0.1067 | No | ||
103 | FMO4 | 13786 | 11581 | -0.023 | 0.1020 | No | ||
104 | RNF121 | 7952 373 | 12048 | -0.031 | 0.0769 | No | ||
105 | PEG3 | 5240 | 12236 | -0.035 | 0.0669 | No | ||
106 | TNFRSF19L | 11498 6727 6726 | 12325 | -0.037 | 0.0623 | No | ||
107 | NRP2 | 5194 9486 5195 | 12343 | -0.038 | 0.0616 | No | ||
108 | DCLRE1A | 23641 | 12480 | -0.041 | 0.0544 | No | ||
109 | CBX5 | 22108 4485 | 12505 | -0.041 | 0.0532 | No | ||
110 | PVRL1 | 3006 19482 12211 7192 | 12855 | -0.050 | 0.0345 | No | ||
111 | DIO3 | 19359 | 13055 | -0.056 | 0.0240 | No | ||
112 | TBX3 | 16723 | 13472 | -0.071 | 0.0017 | No | ||
113 | AP1S2 | 8423 4228 | 13489 | -0.072 | 0.0012 | No | ||
114 | RPS6KA5 | 2076 21005 | 13512 | -0.073 | 0.0003 | No | ||
115 | JPH1 | 13994 | 13674 | -0.082 | -0.0081 | No | ||
116 | KCNA6 | 664 16990 665 4938 | 13927 | -0.097 | -0.0214 | No | ||
117 | SLC16A2 | 24086 | 13972 | -0.100 | -0.0233 | No | ||
118 | BMP7 | 14324 | 14065 | -0.107 | -0.0279 | No | ||
119 | H2AFZ | 6957 | 14069 | -0.108 | -0.0276 | No | ||
120 | GPRC5B | 17662 | 14414 | -0.142 | -0.0456 | No | ||
121 | DDB2 | 2721 2878 14525 2661 | 14421 | -0.143 | -0.0454 | No | ||
122 | PCSK4 | 19696 3296 3394 18705 | 14570 | -0.160 | -0.0527 | No | ||
123 | DMD | 24295 2647 | 14621 | -0.170 | -0.0548 | No | ||
124 | AP4M1 | 3499 16656 | 14702 | -0.183 | -0.0583 | No | ||
125 | ERBB2IP | 3232 12234 | 14739 | -0.190 | -0.0595 | No | ||
126 | FANCG | 15904 | 14741 | -0.191 | -0.0588 | No | ||
127 | DMRT1 | 23899 | 15095 | -0.263 | -0.0768 | No | ||
128 | PTMA | 9657 | 15118 | -0.268 | -0.0769 | No | ||
129 | HMGN2 | 9095 | 15229 | -0.297 | -0.0816 | No | ||
130 | ERF | 4680 8914 | 15283 | -0.315 | -0.0832 | No | ||
131 | MYC | 22465 9435 | 15334 | -0.330 | -0.0846 | No | ||
132 | ZCCHC8 | 3570 7696 | 15368 | -0.339 | -0.0850 | No | ||
133 | KLF5 | 4456 | 15510 | -0.399 | -0.0909 | No | ||
134 | ETV4 | 20212 | 15513 | -0.403 | -0.0894 | No | ||
135 | ORC1L | 327 16144 | 15837 | -0.579 | -0.1045 | No | ||
136 | MCM6 | 4000 13845 4119 | 15865 | -0.608 | -0.1035 | No | ||
137 | STAG2 | 5521 | 16122 | -0.850 | -0.1138 | No | ||
138 | ATE1 | 388 17602 | 16199 | -0.926 | -0.1141 | No | ||
139 | BRMS1L | 21268 | 16232 | -0.966 | -0.1119 | No | ||
140 | ANP32E | 15500 | 16247 | -0.977 | -0.1086 | No | ||
141 | ABCF2 | 11338 6580 6579 | 16260 | -0.987 | -0.1052 | No | ||
142 | HNRPA1 | 9103 4860 | 16286 | -0.999 | -0.1025 | No | ||
143 | NDUFA11 | 12832 | 16348 | -1.042 | -0.1015 | No | ||
144 | FBXL20 | 13010 | 16688 | -1.488 | -0.1137 | No | ||
145 | MAP4K1 | 18313 | 16775 | -1.624 | -0.1117 | No | ||
146 | HRBL | 3452 16326 3614 | 16853 | -1.724 | -0.1088 | No | ||
147 | USP52 | 3397 19841 | 16964 | -1.853 | -0.1071 | No | ||
148 | NHLRC2 | 23828 | 17254 | -2.335 | -0.1131 | No | ||
149 | POLE4 | 12441 | 17259 | -2.349 | -0.1037 | No | ||
150 | MAT2A | 10553 10554 6099 | 17281 | -2.385 | -0.0950 | No | ||
151 | CTCF | 18490 | 17307 | -2.434 | -0.0863 | No | ||
152 | GPS2 | 12096 | 17482 | -2.830 | -0.0841 | No | ||
153 | AXUD1 | 18967 | 17830 | -3.686 | -0.0877 | No | ||
154 | DCK | 16808 | 17923 | -3.959 | -0.0764 | No | ||
155 | PPM1D | 20721 | 18053 | -4.474 | -0.0650 | No | ||
156 | RAB11B | 9676 | 18106 | -4.643 | -0.0487 | No | ||
157 | PPP1R9B | 20698 | 18242 | -5.266 | -0.0343 | No | ||
158 | MXD3 | 21455 | 18295 | -5.505 | -0.0145 | No | ||
159 | FBXO9 | 19058 3146 | 18531 | -7.726 | 0.0046 | No |