Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | DMpreB |
GeneSet | V$E2F_02 |
Enrichment Score (ES) | 0.5512171 |
Normalized Enrichment Score (NES) | 1.3798904 |
Nominal p-value | 0.010118044 |
FDR q-value | 0.32158026 |
FWER p-Value | 0.999 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | EIF4A1 | 8889 23719 | 80 | 8.676 | 0.0300 | Yes | ||
2 | SNRPD1 | 23622 | 185 | 7.175 | 0.0528 | Yes | ||
3 | MSH2 | 23138 | 212 | 6.910 | 0.0788 | Yes | ||
4 | NASP | 2383 2387 6955 | 263 | 6.510 | 0.1019 | Yes | ||
5 | CDCA7 | 12437 | 293 | 6.274 | 0.1252 | Yes | ||
6 | UNG | 10257 16744 | 315 | 6.124 | 0.1483 | Yes | ||
7 | NOLC1 | 7704 | 329 | 5.999 | 0.1714 | Yes | ||
8 | FANCD2 | 17326 464 | 350 | 5.936 | 0.1938 | Yes | ||
9 | MCM3 | 13991 | 390 | 5.583 | 0.2139 | Yes | ||
10 | FKBP5 | 23051 | 439 | 5.349 | 0.2325 | Yes | ||
11 | DNMT1 | 19217 | 456 | 5.277 | 0.2525 | Yes | ||
12 | RQCD1 | 12205 | 475 | 5.201 | 0.2721 | Yes | ||
13 | MCM7 | 9372 3568 | 497 | 5.089 | 0.2912 | Yes | ||
14 | MCM2 | 17074 | 598 | 4.627 | 0.3041 | Yes | ||
15 | AP1S1 | 3500 3453 16335 | 606 | 4.606 | 0.3220 | Yes | ||
16 | CDC25A | 8721 | 631 | 4.494 | 0.3385 | Yes | ||
17 | GSPT1 | 9046 | 684 | 4.328 | 0.3528 | Yes | ||
18 | MRPL40 | 22641 | 728 | 4.188 | 0.3671 | Yes | ||
19 | PHF5A | 22194 | 738 | 4.141 | 0.3830 | Yes | ||
20 | ACBD6 | 14089 | 743 | 4.124 | 0.3991 | Yes | ||
21 | PRPS1 | 24233 | 804 | 3.939 | 0.4115 | Yes | ||
22 | NCL | 5153 13899 | 818 | 3.882 | 0.4262 | Yes | ||
23 | GMNN | 21513 | 848 | 3.827 | 0.4397 | Yes | ||
24 | ACO2 | 8527 | 968 | 3.418 | 0.4468 | Yes | ||
25 | HMGA1 | 23323 | 1003 | 3.313 | 0.4581 | Yes | ||
26 | SMAD6 | 19083 | 1038 | 3.214 | 0.4690 | Yes | ||
27 | PCNA | 9535 | 1100 | 3.074 | 0.4779 | Yes | ||
28 | SUV39H1 | 24194 | 1202 | 2.857 | 0.4838 | Yes | ||
29 | HIRA | 4852 9090 | 1204 | 2.854 | 0.4950 | Yes | ||
30 | PRPS2 | 24003 | 1345 | 2.528 | 0.4974 | Yes | ||
31 | MAP3K7 | 16255 | 1398 | 2.420 | 0.5042 | Yes | ||
32 | NUP62 | 9497 | 1445 | 2.341 | 0.5110 | Yes | ||
33 | FANCC | 4712 | 1556 | 2.184 | 0.5137 | Yes | ||
34 | SUMO1 | 5826 3943 10247 | 1636 | 2.077 | 0.5177 | Yes | ||
35 | EED | 17759 | 1687 | 1.998 | 0.5229 | Yes | ||
36 | HTF9C | 4886 1678 | 1702 | 1.969 | 0.5299 | Yes | ||
37 | ILF3 | 3110 3030 9176 | 1753 | 1.884 | 0.5347 | Yes | ||
38 | RRM2 | 5401 5400 | 1791 | 1.841 | 0.5400 | Yes | ||
39 | STMN1 | 9261 | 1819 | 1.798 | 0.5456 | Yes | ||
40 | POLD3 | 17742 | 1845 | 1.754 | 0.5512 | Yes | ||
41 | SFRS1 | 8492 | 2072 | 1.466 | 0.5448 | No | ||
42 | USP37 | 13923 | 2107 | 1.433 | 0.5486 | No | ||
43 | E2F3 | 21500 8874 | 2367 | 1.098 | 0.5389 | No | ||
44 | MAPK6 | 19062 | 2402 | 1.062 | 0.5413 | No | ||
45 | SFRS7 | 22889 | 2416 | 1.053 | 0.5448 | No | ||
46 | CLSPN | 16079 11256 6530 | 2461 | 1.017 | 0.5464 | No | ||
47 | POLR2A | 5394 | 2654 | 0.858 | 0.5394 | No | ||
48 | MAPT | 9420 1347 | 2946 | 0.604 | 0.5261 | No | ||
49 | PAQR4 | 23105 | 3014 | 0.549 | 0.5246 | No | ||
50 | NR6A1 | 14596 | 3015 | 0.547 | 0.5268 | No | ||
51 | ARID4A | 2080 6215 | 3041 | 0.533 | 0.5275 | No | ||
52 | E2F7 | 19884 | 3187 | 0.447 | 0.5215 | No | ||
53 | MSH5 | 23010 1599 | 3230 | 0.429 | 0.5209 | No | ||
54 | YBX2 | 20818 | 3538 | 0.316 | 0.5055 | No | ||
55 | HOXC10 | 22342 | 3555 | 0.312 | 0.5059 | No | ||
56 | SYNCRIP | 3078 3035 3107 | 3939 | 0.225 | 0.4860 | No | ||
57 | GATA1 | 24196 | 3956 | 0.221 | 0.4860 | No | ||
58 | PHC1 | 17013 | 3963 | 0.220 | 0.4866 | No | ||
59 | MCM4 | 22655 1708 | 4196 | 0.186 | 0.4747 | No | ||
60 | ASXL2 | 7957 | 4207 | 0.184 | 0.4749 | No | ||
61 | SYNGR4 | 17825 | 4350 | 0.166 | 0.4679 | No | ||
62 | E2F1 | 14384 | 4565 | 0.144 | 0.4569 | No | ||
63 | SEMA6A | 23439 9802 | 4940 | 0.116 | 0.4371 | No | ||
64 | PHF15 | 20467 8050 | 5571 | 0.083 | 0.4033 | No | ||
65 | RANBP1 | 9692 5357 | 5854 | 0.071 | 0.3883 | No | ||
66 | GRIA4 | 19249 | 5979 | 0.067 | 0.3819 | No | ||
67 | ZBTB4 | 13267 | 6030 | 0.066 | 0.3794 | No | ||
68 | CDC6 | 6221 6220 | 6125 | 0.063 | 0.3746 | No | ||
69 | PODN | 15811 | 6202 | 0.060 | 0.3707 | No | ||
70 | HNRPUL1 | 6118 17923 1608 10577 1345 | 6262 | 0.059 | 0.3677 | No | ||
71 | RBL1 | 14373 | 6291 | 0.058 | 0.3664 | No | ||
72 | PRKDC | 9617 22847 | 6336 | 0.057 | 0.3643 | No | ||
73 | TYRO3 | 5811 | 6547 | 0.052 | 0.3531 | No | ||
74 | ATAD2 | 2268 2256 | 6586 | 0.051 | 0.3513 | No | ||
75 | HNRPA2B1 | 1187 7001 7000 1040 | 6854 | 0.045 | 0.3370 | No | ||
76 | EPHB1 | 19024 | 6869 | 0.045 | 0.3364 | No | ||
77 | PCSK1 | 21600 | 7368 | 0.035 | 0.3096 | No | ||
78 | HNRPD | 8645 | 7481 | 0.033 | 0.3036 | No | ||
79 | FBXO5 | 19830 | 7525 | 0.032 | 0.3014 | No | ||
80 | STAG1 | 5520 9905 2987 | 7660 | 0.030 | 0.2943 | No | ||
81 | MYH10 | 8077 | 7788 | 0.028 | 0.2875 | No | ||
82 | PRPF4B | 3208 5295 | 7901 | 0.026 | 0.2816 | No | ||
83 | SFRS10 | 9818 1722 5441 | 8002 | 0.025 | 0.2762 | No | ||
84 | CBX3 | 8705 4484 | 8059 | 0.024 | 0.2733 | No | ||
85 | TBX6 | 1993 18075 | 8478 | 0.018 | 0.2507 | No | ||
86 | POU4F1 | 21727 | 8564 | 0.017 | 0.2462 | No | ||
87 | STK35 | 14851 | 8658 | 0.016 | 0.2412 | No | ||
88 | MAZ | 1327 17623 | 8787 | 0.014 | 0.2343 | No | ||
89 | ADAMTS2 | 5706 20899 1356 | 9005 | 0.012 | 0.2226 | No | ||
90 | PAX6 | 5223 | 9241 | 0.009 | 0.2099 | No | ||
91 | GLRA3 | 18617 | 9309 | 0.008 | 0.2063 | No | ||
92 | HS6ST3 | 21933 | 9385 | 0.007 | 0.2023 | No | ||
93 | TOPBP1 | 10659 | 9405 | 0.006 | 0.2013 | No | ||
94 | PLAGL1 | 10372 3414 | 9975 | -0.001 | 0.1705 | No | ||
95 | HCN3 | 4843 1763 | 10154 | -0.003 | 0.1609 | No | ||
96 | SP3 | 5483 | 10159 | -0.003 | 0.1607 | No | ||
97 | NRK | 6559 | 10342 | -0.005 | 0.1508 | No | ||
98 | CASP8AP2 | 16253 | 10367 | -0.005 | 0.1495 | No | ||
99 | SLCO3A1 | 17796 4237 8430 | 10399 | -0.006 | 0.1479 | No | ||
100 | GABRB3 | 4747 | 10880 | -0.012 | 0.1219 | No | ||
101 | POLE2 | 21053 | 10899 | -0.013 | 0.1210 | No | ||
102 | IPO7 | 6130 | 11087 | -0.015 | 0.1109 | No | ||
103 | EZH2 | 1092 17163 | 11493 | -0.021 | 0.0891 | No | ||
104 | FMO4 | 13786 | 11581 | -0.023 | 0.0845 | No | ||
105 | DNAJC9 | 21912 | 12010 | -0.030 | 0.0614 | No | ||
106 | PEG3 | 5240 | 12236 | -0.035 | 0.0494 | No | ||
107 | RET | 17028 | 13319 | -0.066 | -0.0090 | No | ||
108 | TMPO | 5778 | 13368 | -0.067 | -0.0113 | No | ||
109 | NELL2 | 12006 7020 22151 | 13383 | -0.068 | -0.0118 | No | ||
110 | RPS6KA5 | 2076 21005 | 13512 | -0.073 | -0.0185 | No | ||
111 | KCNS2 | 4949 2232 | 13656 | -0.081 | -0.0259 | No | ||
112 | MCM8 | 14834 | 13711 | -0.084 | -0.0285 | No | ||
113 | TLE3 | 5767 19416 | 13855 | -0.092 | -0.0359 | No | ||
114 | ARHGAP6 | 24207 | 13898 | -0.095 | -0.0378 | No | ||
115 | KCNA6 | 664 16990 665 4938 | 13927 | -0.097 | -0.0389 | No | ||
116 | H2AFZ | 6957 | 14069 | -0.108 | -0.0461 | No | ||
117 | EFNA5 | 4655 8884 | 14410 | -0.142 | -0.0639 | No | ||
118 | GPRC5B | 17662 | 14414 | -0.142 | -0.0635 | No | ||
119 | DMD | 24295 2647 | 14621 | -0.170 | -0.0740 | No | ||
120 | AP4M1 | 3499 16656 | 14702 | -0.183 | -0.0776 | No | ||
121 | FANCG | 15904 | 14741 | -0.191 | -0.0789 | No | ||
122 | PTMA | 9657 | 15118 | -0.268 | -0.0982 | No | ||
123 | MYC | 22465 9435 | 15334 | -0.330 | -0.1086 | No | ||
124 | ZCCHC8 | 3570 7696 | 15368 | -0.339 | -0.1090 | No | ||
125 | HNRPR | 13196 7909 2500 | 15460 | -0.375 | -0.1125 | No | ||
126 | ATF5 | 17843 | 15505 | -0.396 | -0.1133 | No | ||
127 | UGCGL1 | 6721 | 15672 | -0.475 | -0.1204 | No | ||
128 | CORT | 15669 2539 | 15707 | -0.497 | -0.1203 | No | ||
129 | BRPF1 | 17332 | 15813 | -0.558 | -0.1237 | No | ||
130 | MCM6 | 4000 13845 4119 | 15865 | -0.608 | -0.1241 | No | ||
131 | RPS20 | 7438 | 15960 | -0.687 | -0.1265 | No | ||
132 | STAG2 | 5521 | 16122 | -0.850 | -0.1318 | No | ||
133 | BRMS1L | 21268 | 16232 | -0.966 | -0.1339 | No | ||
134 | CDC5L | 7746 7745 7744 | 16311 | -1.009 | -0.1341 | No | ||
135 | CCNT1 | 22140 11607 | 16429 | -1.133 | -0.1360 | No | ||
136 | HIST1H2AH | 11414 | 16447 | -1.152 | -0.1323 | No | ||
137 | ING3 | 17514 1019 | 16667 | -1.449 | -0.1384 | No | ||
138 | FHOD1 | 18772 | 16792 | -1.656 | -0.1386 | No | ||
139 | ALDH6A1 | 21025 | 16891 | -1.754 | -0.1369 | No | ||
140 | USP52 | 3397 19841 | 16964 | -1.853 | -0.1335 | No | ||
141 | SLC9A7 | 24177 | 16967 | -1.861 | -0.1262 | No | ||
142 | POLE4 | 12441 | 17259 | -2.349 | -0.1327 | No | ||
143 | POLD1 | 17847 | 17439 | -2.709 | -0.1317 | No | ||
144 | PIM1 | 23308 | 17500 | -2.869 | -0.1235 | No | ||
145 | HIST1H2BK | 11423 | 17694 | -3.349 | -0.1207 | No | ||
146 | HIST1H4A | 11590 | 17700 | -3.358 | -0.1077 | No | ||
147 | TRIM39 | 22994 | 17740 | -3.476 | -0.0960 | No | ||
148 | AK2 | 8563 2479 16073 | 17761 | -3.520 | -0.0832 | No | ||
149 | SOAT1 | 13797 | 17882 | -3.831 | -0.0745 | No | ||
150 | DCK | 16808 | 17923 | -3.959 | -0.0609 | No | ||
151 | PPM1D | 20721 | 18053 | -4.474 | -0.0502 | No | ||
152 | H2AFV | 1273 20531 | 18261 | -5.343 | -0.0402 | No | ||
153 | MXD3 | 21455 | 18295 | -5.505 | -0.0202 | No | ||
154 | IL4I1 | 8971 | 18606 | -9.474 | 0.0005 | No |