Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | DMpreB |
GeneSet | V$E2F1_Q6_01 |
Enrichment Score (ES) | 0.58248365 |
Normalized Enrichment Score (NES) | 1.4607793 |
Nominal p-value | 0.0 |
FDR q-value | 0.5214838 |
FWER p-Value | 0.954 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PPRC1 | 23808 | 151 | 7.606 | 0.0247 | Yes | ||
2 | MSH2 | 23138 | 212 | 6.910 | 0.0514 | Yes | ||
3 | NASP | 2383 2387 6955 | 263 | 6.510 | 0.0768 | Yes | ||
4 | CDCA7 | 12437 | 293 | 6.274 | 0.1024 | Yes | ||
5 | UNG | 10257 16744 | 315 | 6.124 | 0.1278 | Yes | ||
6 | NOLC1 | 7704 | 329 | 5.999 | 0.1530 | Yes | ||
7 | MCM3 | 13991 | 390 | 5.583 | 0.1739 | Yes | ||
8 | FKBP5 | 23051 | 439 | 5.349 | 0.1944 | Yes | ||
9 | DNMT1 | 19217 | 456 | 5.277 | 0.2164 | Yes | ||
10 | RQCD1 | 12205 | 475 | 5.201 | 0.2379 | Yes | ||
11 | MCM7 | 9372 3568 | 497 | 5.089 | 0.2588 | Yes | ||
12 | ATP5G2 | 12610 | 588 | 4.682 | 0.2742 | Yes | ||
13 | MCM2 | 17074 | 598 | 4.627 | 0.2937 | Yes | ||
14 | AP1S1 | 3500 3453 16335 | 606 | 4.606 | 0.3133 | Yes | ||
15 | CDC25A | 8721 | 631 | 4.494 | 0.3314 | Yes | ||
16 | GSPT1 | 9046 | 684 | 4.328 | 0.3473 | Yes | ||
17 | MRPL40 | 22641 | 728 | 4.188 | 0.3631 | Yes | ||
18 | POLA2 | 23988 | 733 | 4.174 | 0.3810 | Yes | ||
19 | PHF5A | 22194 | 738 | 4.141 | 0.3987 | Yes | ||
20 | ACBD6 | 14089 | 743 | 4.124 | 0.4163 | Yes | ||
21 | PRPS1 | 24233 | 804 | 3.939 | 0.4301 | Yes | ||
22 | NCL | 5153 13899 | 818 | 3.882 | 0.4462 | Yes | ||
23 | GMNN | 21513 | 848 | 3.827 | 0.4611 | Yes | ||
24 | ACO2 | 8527 | 968 | 3.418 | 0.4695 | Yes | ||
25 | PCNA | 9535 | 1100 | 3.074 | 0.4757 | Yes | ||
26 | RPS19 | 5398 | 1114 | 3.041 | 0.4881 | Yes | ||
27 | PPP1R8 | 15730 | 1138 | 2.994 | 0.4998 | Yes | ||
28 | SUV39H1 | 24194 | 1202 | 2.857 | 0.5088 | Yes | ||
29 | HIRA | 4852 9090 | 1204 | 2.854 | 0.5211 | Yes | ||
30 | FANCC | 4712 | 1556 | 2.184 | 0.5115 | Yes | ||
31 | SUMO1 | 5826 3943 10247 | 1636 | 2.077 | 0.5162 | Yes | ||
32 | SLC25A1 | 22645 | 1667 | 2.031 | 0.5234 | Yes | ||
33 | INSM1 | 14815 | 1670 | 2.029 | 0.5320 | Yes | ||
34 | EED | 17759 | 1687 | 1.998 | 0.5398 | Yes | ||
35 | HTF9C | 4886 1678 | 1702 | 1.969 | 0.5476 | Yes | ||
36 | ILF3 | 3110 3030 9176 | 1753 | 1.884 | 0.5530 | Yes | ||
37 | STMN1 | 9261 | 1819 | 1.798 | 0.5573 | Yes | ||
38 | POLD3 | 17742 | 1845 | 1.754 | 0.5635 | Yes | ||
39 | DNAJC11 | 2486 6068 | 1924 | 1.635 | 0.5664 | Yes | ||
40 | SFRS1 | 8492 | 2072 | 1.466 | 0.5647 | Yes | ||
41 | USP37 | 13923 | 2107 | 1.433 | 0.5691 | Yes | ||
42 | SIN3A | 5442 | 2148 | 1.383 | 0.5729 | Yes | ||
43 | AMD1 | 8583 | 2190 | 1.323 | 0.5764 | Yes | ||
44 | E2F3 | 21500 8874 | 2367 | 1.098 | 0.5716 | Yes | ||
45 | PHF13 | 15659 | 2372 | 1.093 | 0.5762 | Yes | ||
46 | CLSPN | 16079 11256 6530 | 2461 | 1.017 | 0.5758 | Yes | ||
47 | FAF1 | 2508 16137 8951 | 2490 | 1.001 | 0.5786 | Yes | ||
48 | UXT | 5837 10267 | 2499 | 0.999 | 0.5825 | Yes | ||
49 | CHD4 | 8418 17281 4225 | 2762 | 0.754 | 0.5715 | No | ||
50 | SFRS2 | 9807 20136 | 2789 | 0.733 | 0.5733 | No | ||
51 | PAQR4 | 23105 | 3014 | 0.549 | 0.5636 | No | ||
52 | NCOA6 | 2876 14382 | 3151 | 0.461 | 0.5582 | No | ||
53 | CASP2 | 8692 | 3192 | 0.445 | 0.5579 | No | ||
54 | WEE1 | 18127 | 3229 | 0.429 | 0.5578 | No | ||
55 | YBX2 | 20818 | 3538 | 0.316 | 0.5425 | No | ||
56 | HOXC10 | 22342 | 3555 | 0.312 | 0.5430 | No | ||
57 | RAD51 | 2897 14903 | 3710 | 0.271 | 0.5358 | No | ||
58 | PCDH10 | 5227 9534 1893 | 3757 | 0.260 | 0.5345 | No | ||
59 | SYNCRIP | 3078 3035 3107 | 3939 | 0.225 | 0.5256 | No | ||
60 | GATA1 | 24196 | 3956 | 0.221 | 0.5257 | No | ||
61 | MCM4 | 22655 1708 | 4196 | 0.186 | 0.5136 | No | ||
62 | ASXL2 | 7957 | 4207 | 0.184 | 0.5138 | No | ||
63 | SYNGR4 | 17825 | 4350 | 0.166 | 0.5069 | No | ||
64 | E2F1 | 14384 | 4565 | 0.144 | 0.4959 | No | ||
65 | CNOT3 | 6112 10565 6113 | 4624 | 0.139 | 0.4933 | No | ||
66 | HMGA2 | 4857 9098 3341 3444 | 5402 | 0.091 | 0.4516 | No | ||
67 | PHF15 | 20467 8050 | 5571 | 0.083 | 0.4429 | No | ||
68 | HR | 3622 9119 | 5698 | 0.077 | 0.4364 | No | ||
69 | RANBP1 | 9692 5357 | 5854 | 0.071 | 0.4283 | No | ||
70 | PODN | 15811 | 6202 | 0.060 | 0.4098 | No | ||
71 | HNRPUL1 | 6118 17923 1608 10577 1345 | 6262 | 0.059 | 0.4068 | No | ||
72 | RBL1 | 14373 | 6291 | 0.058 | 0.4056 | No | ||
73 | PRKDC | 9617 22847 | 6336 | 0.057 | 0.4034 | No | ||
74 | TYRO3 | 5811 | 6547 | 0.052 | 0.3923 | No | ||
75 | ATAD2 | 2268 2256 | 6586 | 0.051 | 0.3904 | No | ||
76 | IRX3 | 18793 | 6613 | 0.051 | 0.3893 | No | ||
77 | RB1CC1 | 4486 14299 | 6748 | 0.047 | 0.3822 | No | ||
78 | SYT6 | 13437 7042 12040 | 6823 | 0.046 | 0.3784 | No | ||
79 | ENPP1 | 19804 | 6838 | 0.046 | 0.3778 | No | ||
80 | UFD1L | 22825 | 7359 | 0.035 | 0.3498 | No | ||
81 | PCSK1 | 21600 | 7368 | 0.035 | 0.3495 | No | ||
82 | HNRPD | 8645 | 7481 | 0.033 | 0.3436 | No | ||
83 | FBXO5 | 19830 | 7525 | 0.032 | 0.3414 | No | ||
84 | RPL18 | 450 5390 | 7540 | 0.032 | 0.3408 | No | ||
85 | DHH | 4629 | 7589 | 0.031 | 0.3383 | No | ||
86 | STAG1 | 5520 9905 2987 | 7660 | 0.030 | 0.3347 | No | ||
87 | MYH10 | 8077 | 7788 | 0.028 | 0.3279 | No | ||
88 | TBX6 | 1993 18075 | 8478 | 0.018 | 0.2907 | No | ||
89 | STK35 | 14851 | 8658 | 0.016 | 0.2810 | No | ||
90 | MAZ | 1327 17623 | 8787 | 0.014 | 0.2742 | No | ||
91 | ADAMTS2 | 5706 20899 1356 | 9005 | 0.012 | 0.2624 | No | ||
92 | PAX6 | 5223 | 9241 | 0.009 | 0.2498 | No | ||
93 | TOPBP1 | 10659 | 9405 | 0.006 | 0.2409 | No | ||
94 | ATM | 2976 19115 | 9513 | 0.005 | 0.2352 | No | ||
95 | CDC45L | 22642 1752 | 9951 | -0.001 | 0.2115 | No | ||
96 | NPAT | 19452 6356 | 10031 | -0.002 | 0.2072 | No | ||
97 | HCN3 | 4843 1763 | 10154 | -0.003 | 0.2006 | No | ||
98 | FZD1 | 16923 | 10236 | -0.004 | 0.1963 | No | ||
99 | CASP8AP2 | 16253 | 10367 | -0.005 | 0.1892 | No | ||
100 | USP2 | 19480 3052 3043 | 10584 | -0.008 | 0.1776 | No | ||
101 | POLE2 | 21053 | 10899 | -0.013 | 0.1606 | No | ||
102 | REPS2 | 24018 | 11031 | -0.014 | 0.1536 | No | ||
103 | IPO7 | 6130 | 11087 | -0.015 | 0.1507 | No | ||
104 | MTSS1 | 5585 22285 | 11237 | -0.018 | 0.1427 | No | ||
105 | EZH2 | 1092 17163 | 11493 | -0.021 | 0.1289 | No | ||
106 | LRP1 | 9284 | 11848 | -0.027 | 0.1099 | No | ||
107 | DNAJC9 | 21912 | 12010 | -0.030 | 0.1013 | No | ||
108 | MGAT2 | 21256 | 12264 | -0.036 | 0.0877 | No | ||
109 | TNFRSF19L | 11498 6727 6726 | 12325 | -0.037 | 0.0846 | No | ||
110 | BMP2 | 14833 | 12361 | -0.038 | 0.0829 | No | ||
111 | GNG4 | 21706 | 12499 | -0.041 | 0.0757 | No | ||
112 | CBX5 | 22108 4485 | 12505 | -0.041 | 0.0756 | No | ||
113 | SPHK2 | 1217 1806 12155 | 13302 | -0.065 | 0.0327 | No | ||
114 | TMPO | 5778 | 13368 | -0.067 | 0.0295 | No | ||
115 | KCNS2 | 4949 2232 | 13656 | -0.081 | 0.0143 | No | ||
116 | TNF | 23004 | 13668 | -0.082 | 0.0141 | No | ||
117 | JPH1 | 13994 | 13674 | -0.082 | 0.0141 | No | ||
118 | MCM8 | 14834 | 13711 | -0.084 | 0.0126 | No | ||
119 | ACTN3 | 23967 8540 | 13826 | -0.090 | 0.0068 | No | ||
120 | ARHGAP6 | 24207 | 13898 | -0.095 | 0.0033 | No | ||
121 | EFNA5 | 4655 8884 | 14410 | -0.142 | -0.0237 | No | ||
122 | GPRC5B | 17662 | 14414 | -0.142 | -0.0233 | No | ||
123 | DDB2 | 2721 2878 14525 2661 | 14421 | -0.143 | -0.0230 | No | ||
124 | SMARCA1 | 24165 | 14638 | -0.172 | -0.0339 | No | ||
125 | AP4M1 | 3499 16656 | 14702 | -0.183 | -0.0366 | No | ||
126 | ERBB2IP | 3232 12234 | 14739 | -0.190 | -0.0377 | No | ||
127 | FANCG | 15904 | 14741 | -0.191 | -0.0369 | No | ||
128 | POU2F1 | 5275 3989 4065 4010 | 15082 | -0.259 | -0.0542 | No | ||
129 | PTMA | 9657 | 15118 | -0.268 | -0.0550 | No | ||
130 | HMGN2 | 9095 | 15229 | -0.297 | -0.0596 | No | ||
131 | ERF | 4680 8914 | 15283 | -0.315 | -0.0611 | No | ||
132 | MYC | 22465 9435 | 15334 | -0.330 | -0.0624 | No | ||
133 | HNRPR | 13196 7909 2500 | 15460 | -0.375 | -0.0676 | No | ||
134 | KLF5 | 4456 | 15510 | -0.399 | -0.0685 | No | ||
135 | NUMA1 | 18167 | 15573 | -0.432 | -0.0700 | No | ||
136 | SP1 | 9852 | 15654 | -0.467 | -0.0723 | No | ||
137 | ORC1L | 327 16144 | 15837 | -0.579 | -0.0797 | No | ||
138 | MCM6 | 4000 13845 4119 | 15865 | -0.608 | -0.0785 | No | ||
139 | STAG2 | 5521 | 16122 | -0.850 | -0.0887 | No | ||
140 | ATE1 | 388 17602 | 16199 | -0.926 | -0.0888 | No | ||
141 | BRMS1L | 21268 | 16232 | -0.966 | -0.0864 | No | ||
142 | HNRPA1 | 9103 4860 | 16286 | -0.999 | -0.0849 | No | ||
143 | CDC5L | 7746 7745 7744 | 16311 | -1.009 | -0.0818 | No | ||
144 | CCNT1 | 22140 11607 | 16429 | -1.133 | -0.0833 | No | ||
145 | HIST1H2AH | 11414 | 16447 | -1.152 | -0.0792 | No | ||
146 | PIK3CD | 9563 | 16730 | -1.548 | -0.0878 | No | ||
147 | MAP4K1 | 18313 | 16775 | -1.624 | -0.0832 | No | ||
148 | FHOD1 | 18772 | 16792 | -1.656 | -0.0769 | No | ||
149 | USP52 | 3397 19841 | 16964 | -1.853 | -0.0781 | No | ||
150 | SLC9A7 | 24177 | 16967 | -1.861 | -0.0702 | No | ||
151 | CTCF | 18490 | 17307 | -2.434 | -0.0780 | No | ||
152 | GADD45B | 19935 | 17545 | -2.955 | -0.0781 | No | ||
153 | HIST1H2BK | 11423 | 17694 | -3.349 | -0.0716 | No | ||
154 | TRIM39 | 22994 | 17740 | -3.476 | -0.0590 | No | ||
155 | AK2 | 8563 2479 16073 | 17761 | -3.520 | -0.0448 | No | ||
156 | PPM1D | 20721 | 18053 | -4.474 | -0.0412 | No | ||
157 | RAB11B | 9676 | 18106 | -4.643 | -0.0240 | No | ||
158 | MXD3 | 21455 | 18295 | -5.505 | -0.0103 | No | ||
159 | FLI1 | 4729 | 18427 | -6.398 | 0.0102 | No |