Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
| Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
| Upregulated in class | WTpreB |
| GeneSet | TCRPATHWAY |
| Enrichment Score (ES) | -0.7707665 |
| Normalized Enrichment Score (NES) | -1.6695101 |
| Nominal p-value | 0.0021978023 |
| FDR q-value | 0.025042688 |
| FWER p-Value | 0.139 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MAPK8 | 6459 | 1644 | 2.061 | -0.0573 | No | ||
| 2 | PTPN7 | 11500 | 2331 | 1.140 | -0.0770 | No | ||
| 3 | PPP3CA | 1863 5284 | 2520 | 0.993 | -0.0721 | No | ||
| 4 | HRAS | 4868 | 2610 | 0.906 | -0.0632 | No | ||
| 5 | CD3D | 19473 | 3849 | 0.241 | -0.1262 | No | ||
| 6 | SHC1 | 9813 9812 5430 | 3936 | 0.225 | -0.1275 | No | ||
| 7 | FYN | 3375 3395 20052 | 5072 | 0.109 | -0.1869 | No | ||
| 8 | CALM1 | 21184 | 6697 | 0.049 | -0.2736 | No | ||
| 9 | CD3E | 8714 | 8077 | 0.024 | -0.3475 | No | ||
| 10 | TRB@ | 1157 | 8532 | 0.017 | -0.3717 | No | ||
| 11 | SYT1 | 5565 | 8949 | 0.012 | -0.3939 | No | ||
| 12 | NFATC4 | 22002 | 10757 | -0.011 | -0.4910 | No | ||
| 13 | CD3G | 19139 | 11522 | -0.022 | -0.5318 | No | ||
| 14 | NFATC2 | 5168 2866 | 11816 | -0.027 | -0.5472 | No | ||
| 15 | PIK3R1 | 3170 | 12502 | -0.041 | -0.5834 | No | ||
| 16 | PLCG1 | 14753 | 12675 | -0.046 | -0.5920 | No | ||
| 17 | SOS1 | 5476 | 13046 | -0.056 | -0.6111 | No | ||
| 18 | PIK3CA | 9562 | 13540 | -0.075 | -0.6365 | No | ||
| 19 | LAT | 17643 | 14176 | -0.117 | -0.6689 | No | ||
| 20 | ZAP70 | 14271 4042 | 14538 | -0.156 | -0.6860 | No | ||
| 21 | FOS | 21202 | 14800 | -0.201 | -0.6970 | No | ||
| 22 | MAP2K1 | 19082 | 15318 | -0.325 | -0.7199 | No | ||
| 23 | LCK | 15746 | 15440 | -0.368 | -0.7209 | No | ||
| 24 | CALM2 | 8681 | 16368 | -1.071 | -0.7546 | Yes | ||
| 25 | RAC1 | 16302 | 16651 | -1.434 | -0.7481 | Yes | ||
| 26 | RASA1 | 10174 | 16815 | -1.689 | -0.7313 | Yes | ||
| 27 | MAPK3 | 6458 11170 | 16931 | -1.809 | -0.7101 | Yes | ||
| 28 | PPP3CB | 5285 | 16941 | -1.823 | -0.6830 | Yes | ||
| 29 | PPP3CC | 21763 | 16961 | -1.850 | -0.6561 | Yes | ||
| 30 | MAP2K4 | 20405 | 17051 | -1.981 | -0.6309 | Yes | ||
| 31 | CALM3 | 8682 | 17069 | -2.011 | -0.6014 | Yes | ||
| 32 | RAF1 | 17035 | 17131 | -2.125 | -0.5725 | Yes | ||
| 33 | PRKCA | 20174 | 17337 | -2.525 | -0.5454 | Yes | ||
| 34 | NFATC1 | 23398 1999 5167 9455 1985 1957 | 17449 | -2.738 | -0.5099 | Yes | ||
| 35 | GRB2 | 20149 | 17590 | -3.055 | -0.4713 | Yes | ||
| 36 | JUN | 15832 | 17687 | -3.335 | -0.4260 | Yes | ||
| 37 | NFATC3 | 5169 | 17772 | -3.544 | -0.3769 | Yes | ||
| 38 | NFKB1 | 15160 | 17789 | -3.591 | -0.3235 | Yes | ||
| 39 | NFKBIA | 21065 | 17838 | -3.699 | -0.2701 | Yes | ||
| 40 | RELA | 23783 | 17959 | -4.092 | -0.2147 | Yes | ||
| 41 | VAV1 | 23173 | 18136 | -4.751 | -0.1523 | Yes | ||
| 42 | PRKCB1 | 1693 9574 | 18292 | -5.486 | -0.0776 | Yes | ||
| 43 | MAP3K1 | 21348 | 18411 | -6.282 | 0.0110 | Yes |
