Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
| Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
| Upregulated in class | WTpreB |
| GeneSet | ST_P38_MAPK_PATHWAY |
| Enrichment Score (ES) | -0.76769584 |
| Normalized Enrichment Score (NES) | -1.6269678 |
| Nominal p-value | 0.0022727272 |
| FDR q-value | 0.030135408 |
| FWER p-Value | 0.319 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MAP3K7 | 16255 | 1398 | 2.420 | -0.0370 | No | ||
| 2 | MYEF2 | 5140 | 1677 | 2.014 | -0.0201 | No | ||
| 3 | MAPK12 | 2182 2215 22164 | 2007 | 1.545 | -0.0134 | No | ||
| 4 | MKNK2 | 3299 9392 | 3518 | 0.322 | -0.0896 | No | ||
| 5 | IL1R1 | 14264 3987 | 3542 | 0.316 | -0.0858 | No | ||
| 6 | SRF | 22961 1597 | 3826 | 0.245 | -0.0972 | No | ||
| 7 | HSPB1 | 4879 | 4020 | 0.211 | -0.1042 | No | ||
| 8 | AKT1 | 8568 | 4218 | 0.183 | -0.1119 | No | ||
| 9 | CREB5 | 10551 | 6052 | 0.065 | -0.2096 | No | ||
| 10 | MAPK13 | 23314 | 6568 | 0.052 | -0.2365 | No | ||
| 11 | MAPK11 | 2264 9618 22163 | 6872 | 0.045 | -0.2521 | No | ||
| 12 | EIF4E | 15403 1827 8890 | 7583 | 0.031 | -0.2898 | No | ||
| 13 | MAP3K10 | 3831 17916 | 8049 | 0.024 | -0.3144 | No | ||
| 14 | MAP3K7IP1 | 2193 2171 22419 | 8368 | 0.020 | -0.3312 | No | ||
| 15 | CDC42 | 4503 8722 4504 2465 | 10407 | -0.006 | -0.4408 | No | ||
| 16 | MAPKAPK5 | 16387 | 10496 | -0.007 | -0.4454 | No | ||
| 17 | MAP3K5 | 20079 11166 | 13364 | -0.067 | -0.5987 | No | ||
| 18 | ATF1 | 8634 4417 | 13485 | -0.072 | -0.6040 | No | ||
| 19 | MAP3K4 | 23126 | 13836 | -0.091 | -0.6214 | No | ||
| 20 | CREB1 | 3990 8782 4558 4093 | 14365 | -0.137 | -0.6476 | No | ||
| 21 | EEF2K | 18101 | 14842 | -0.208 | -0.6700 | No | ||
| 22 | NR2C2 | 10216 | 15085 | -0.260 | -0.6789 | No | ||
| 23 | MAP2K3 | 20856 | 16736 | -1.563 | -0.7430 | Yes | ||
| 24 | MAP2K4 | 20405 | 17051 | -1.981 | -0.7286 | Yes | ||
| 25 | MAP2K6 | 20614 1414 | 17087 | -2.043 | -0.6982 | Yes | ||
| 26 | MKNK1 | 2504 | 17183 | -2.207 | -0.6684 | Yes | ||
| 27 | CREB3 | 16231 | 17406 | -2.658 | -0.6383 | Yes | ||
| 28 | MAPK14 | 23313 | 17421 | -2.682 | -0.5967 | Yes | ||
| 29 | DUSP10 | 4003 14016 | 17669 | -3.295 | -0.5579 | Yes | ||
| 30 | NFKB1 | 15160 | 17789 | -3.591 | -0.5075 | Yes | ||
| 31 | DUSP1 | 23061 | 18109 | -4.651 | -0.4512 | Yes | ||
| 32 | MAP3K7IP2 | 19827 | 18113 | -4.662 | -0.3776 | Yes | ||
| 33 | TRAF6 | 5797 14940 | 18115 | -4.665 | -0.3040 | Yes | ||
| 34 | GADD45A | 17129 | 18299 | -5.514 | -0.2266 | Yes | ||
| 35 | MAPKAPK2 | 13838 | 18416 | -6.306 | -0.1332 | Yes | ||
| 36 | MAPK1 | 1642 11167 | 18592 | -9.104 | 0.0013 | Yes |
