Details for gene set HSA04660_T_CELL_RECEPTOR_SIGNALING

Table: GSEA Results Summary

Dataset	Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB
Phenotype	phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	HSA04660_T_CELL_RECEPTOR_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.67080677
Normalized Enrichment Score (NES)	-1.6474696
Nominal p-value	0.0026525198
FDR q-value	0.030807048
FWER p-Value	0.224

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PIK3CB	19030	626	4.520	0.0067	No
2	PDK1	14987	702	4.264	0.0409	No
3	PIK3R3	5248	1211	2.839	0.0389	No
4	MALT1	6274	1985	1.573	0.0112	No
5	CHUK	23665	2157	1.372	0.0143	No
6	PPP3CA	1863 5284	2520	0.993	0.0037	No
7	HRAS	4868	2610	0.906	0.0070	No
8	IKBKB	4907	2775	0.746	0.0048	No
9	CDK4	3424 19859	3277	0.401	-0.0186	No
10	VAV3	1774 1848 15443	3695	0.275	-0.0387	No
11	CD3D	19473	3849	0.241	-0.0448	No
12	PIK3R2	18850	3888	0.232	-0.0448	No
13	AKT1	8568	4218	0.183	-0.0609	No
14	IL4	9174	4886	0.119	-0.0958	No
15	FYN	3375 3395 20052	5072	0.109	-0.1048	No
16	ITK	4934	5197	0.102	-0.1106	No
17	CD4	16999	5252	0.099	-0.1126	No
18	PAK3	9528	5621	0.081	-0.1318	No
19	RASGRP1	5360 14476 9694	5625	0.080	-0.1312	No
20	IL5	20884 10220	6018	0.066	-0.1518	No
21	GRAP2	5113 9398	6102	0.063	-0.1557	No
22	AKT2	4365 4366	6728	0.048	-0.1890	No
23	NRAS	5191	6779	0.047	-0.1913	No
24	PAK1	9527	7590	0.031	-0.2347	No
25	IL10	14145 1510 1553 22902	7653	0.030	-0.2378	No
26	NCK1	9447 5152	7819	0.028	-0.2465	No
27	CD3E	8714	8077	0.024	-0.2601	No
28	RHOA	8624 4409 4410	8261	0.021	-0.2698	No
29	CD40LG	24330	8297	0.020	-0.2715	No
30	PIK3R5	11507	8444	0.019	-0.2792	No
31	IL2	15354	8580	0.017	-0.2864	No
32	CD28	14239 4092	8632	0.016	-0.2890	No
33	CD247	4498 8715	9036	0.011	-0.3106	No
34	NFKB2	23810	9535	0.005	-0.3375	No
35	PAK7	14417	9553	0.005	-0.3383	No
36	PPP3R2	9612	9858	0.001	-0.3547	No
37	ICOS	12013	10231	-0.004	-0.3748	No
38	CBLC	17938	10261	-0.004	-0.3763	No
39	CDC42	4503 8722 4504 2465	10407	-0.006	-0.3841	No
40	NFATC4	22002	10757	-0.011	-0.4028	No
41	CD3G	19139	11522	-0.022	-0.4439	No
42	PPP3R1	9611 489	11661	-0.024	-0.4511	No
43	CTLA4	14238	11696	-0.025	-0.4527	No
44	NFATC2	5168 2866	11816	-0.027	-0.4589	No
45	IKBKG	2570 2562 4908	11885	-0.028	-0.4623	No
46	PDCD1	13870	12086	-0.032	-0.4728	No
47	PIK3R1	3170	12502	-0.041	-0.4949	No
48	PLCG1	14753	12675	-0.046	-0.5037	No
49	CSF2	20454	12732	-0.047	-0.5063	No
50	SOS1	5476	13046	-0.056	-0.5227	No
51	PIK3CA	9562	13540	-0.075	-0.5487	No
52	TNF	23004	13668	-0.082	-0.5548	No
53	CD8B	4502 17418	13714	-0.084	-0.5565	No
54	NFAT5	3921 7037 12036	13961	-0.099	-0.5689	No
55	LAT	17643	14176	-0.117	-0.5794	No
56	LCP2	4988 9268	14508	-0.152	-0.5959	No
57	ZAP70	14271 4042	14538	-0.156	-0.5960	No
58	CBL	19154	14602	-0.166	-0.5979	No
59	NFKBIB	17906	14778	-0.198	-0.6056	No
60	FOS	21202	14800	-0.201	-0.6049	No
61	PRKCQ	2873 2831	14829	-0.205	-0.6046	No
62	VAV2	5848 2670	14978	-0.236	-0.6105	No
63	LCK	15746	15440	-0.368	-0.6321	No
64	IFNG	19869	15478	-0.380	-0.6307	No
65	PTPRC	5327 9662	15564	-0.428	-0.6314	No
66	PAK2	10310 5875	15938	-0.671	-0.6456	No
67	MAP3K8	23495	16016	-0.736	-0.6431	No
68	NCK2	9448	16530	-1.250	-0.6596	Yes
69	PAK4	17909	16640	-1.423	-0.6527	Yes
70	PIK3CD	9563	16730	-1.548	-0.6437	Yes
71	AKT3	13739 982	16769	-1.612	-0.6313	Yes
72	PPP3CB	5285	16941	-1.823	-0.6242	Yes
73	PPP3CC	21763	16961	-1.850	-0.6086	Yes
74	TEC	16514	17287	-2.394	-0.6047	Yes
75	SOS2	21049	17328	-2.499	-0.5845	Yes
76	NFATC1	23398 1999 5167 9455 1985 1957	17449	-2.738	-0.5664	Yes
77	CARD11	8436	17478	-2.819	-0.5427	Yes
78	GRB2	20149	17590	-3.055	-0.5213	Yes
79	JUN	15832	17687	-3.335	-0.4966	Yes
80	NFATC3	5169	17772	-3.544	-0.4694	Yes
81	NFKB1	15160	17789	-3.591	-0.4381	Yes
82	MAP3K14	11998	17837	-3.699	-0.4075	Yes
83	NFKBIA	21065	17838	-3.699	-0.3743	Yes
84	BCL10	15397	18081	-4.569	-0.3465	Yes
85	VAV1	23173	18136	-4.751	-0.3068	Yes
86	CBLB	5531 22734	18225	-5.154	-0.2654	Yes
87	KRAS	9247	18396	-6.150	-0.2195	Yes
88	PTPN6	17002	18561	-8.216	-0.1547	Yes
89	NFKBIE	23225 1556	18579	-8.741	-0.0773	Yes
90	PIK3CG	6635	18583	-8.846	0.0018	Yes