Details for gene set HSA04650_NATURAL_KILLER_CELL_MEDIATED

Table: GSEA Results Summary

Dataset	Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB
Phenotype	phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	HSA04650_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY
Enrichment Score (ES)	-0.65362924
Normalized Enrichment Score (NES)	-1.6295093
Nominal p-value	0.0
FDR q-value	0.034952547
FWER p-Value	0.305

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CD48	14051	548	4.836	0.0060	No
2	PIK3CB	19030	626	4.520	0.0352	No
3	HCST	6237	866	3.779	0.0501	No
4	PIK3R3	5248	1211	2.839	0.0524	No
5	CASP3	8693	1584	2.145	0.0481	No
6	FCER1G	13759	1625	2.092	0.0614	No
7	BID	17017 435	1954	1.590	0.0554	No
8	PPP3CA	1863 5284	2520	0.993	0.0322	No
9	HRAS	4868	2610	0.906	0.0341	No
10	VAV3	1774 1848 15443	3695	0.275	-0.0224	No
11	PIK3R2	18850	3888	0.232	-0.0311	No
12	SHC1	9813 9812 5430	3936	0.225	-0.0320	No
13	IFNA1	9147	4153	0.191	-0.0422	No
14	TNFRSF10B	21971 10205 5781 10204	4210	0.184	-0.0439	No
15	FYN	3375 3395 20052	5072	0.109	-0.0896	No
16	TNFSF10	15626	5420	0.090	-0.1077	No
17	IFNA7	9152	5600	0.082	-0.1167	No
18	NRAS	5191	6779	0.047	-0.1800	No
19	IFNA14	11917	7024	0.042	-0.1929	No
20	IFNA6	17749	7067	0.041	-0.1948	No
21	IFNB1	15846	7388	0.035	-0.2118	No
22	KIR3DL1	2611 6365	7433	0.034	-0.2140	No
23	IFNA2	9149	7465	0.033	-0.2154	No
24	PAK1	9527	7590	0.031	-0.2219	No
25	PIK3R5	11507	8444	0.019	-0.2678	No
26	SHC3	21465	8738	0.015	-0.2835	No
27	CD247	4498 8715	9036	0.011	-0.2994	No
28	PTPN11	5326 16391 9660	9360	0.007	-0.3168	No
29	KLRC1	9242	9547	0.005	-0.3268	No
30	PRF1	20011	9734	0.002	-0.3369	No
31	PPP3R2	9612	9858	0.001	-0.3435	No
32	SH2D1A	9810	10059	-0.002	-0.3543	No
33	NCR1	18409	10246	-0.004	-0.3643	No
34	SH2D1B	14061	10433	-0.006	-0.3743	No
35	RAC3	20561	10656	-0.009	-0.3862	No
36	NFATC4	22002	10757	-0.011	-0.3915	No
37	IFNA13	15844	11243	-0.018	-0.4176	No
38	KLRC3	16975	11351	-0.019	-0.4232	No
39	IFNA4	9150	11609	-0.023	-0.4369	No
40	PPP3R1	9611 489	11661	-0.024	-0.4395	No
41	NFATC2	5168 2866	11816	-0.027	-0.4476	No
42	PIK3R1	3170	12502	-0.041	-0.4843	No
43	GZMB	21810	12565	-0.043	-0.4873	No
44	PLCG1	14753	12675	-0.046	-0.4929	No
45	CSF2	20454	12732	-0.047	-0.4956	No
46	IFNAR1	22703	12857	-0.050	-0.5019	No
47	SOS1	5476	13046	-0.056	-0.5116	No
48	PIK3CA	9562	13540	-0.075	-0.5377	No
49	TNF	23004	13668	-0.082	-0.5439	No
50	KLRC2	9243	13960	-0.099	-0.5589	No
51	NFAT5	3921 7037 12036	13961	-0.099	-0.5582	No
52	IFNA5	9151	14080	-0.109	-0.5638	No
53	LAT	17643	14176	-0.117	-0.5680	No
54	LCP2	4988 9268	14508	-0.152	-0.5848	No
55	FASLG	13789	14511	-0.153	-0.5838	No
56	ZAP70	14271 4042	14538	-0.156	-0.5840	No
57	KLRK1	6544 16976 11281	14641	-0.173	-0.5883	No
58	FCGR3A	8960	14882	-0.215	-0.5996	No
59	MAP2K2	19933	14908	-0.221	-0.5994	No
60	VAV2	5848 2670	14978	-0.236	-0.6013	No
61	IFNAR2	22705 1699	15148	-0.277	-0.6084	No
62	MAP2K1	19082	15318	-0.325	-0.6152	No
63	LCK	15746	15440	-0.368	-0.6190	No
64	ITGAL	9187	15467	-0.377	-0.6176	No
65	IFNG	19869	15478	-0.380	-0.6154	No
66	FAS	23881 3750	15710	-0.499	-0.6242	No
67	ARAF	24367	16058	-0.778	-0.6372	No
68	KLRD1	17266	16214	-0.939	-0.6386	No
69	TYROBP	18302	16254	-0.981	-0.6335	No
70	IFNGR1	20083	16628	-1.403	-0.6433	Yes
71	RAC1	16302	16651	-1.434	-0.6339	Yes
72	PIK3CD	9563	16730	-1.548	-0.6267	Yes
73	ITGB2	19978	16756	-1.593	-0.6163	Yes
74	MAPK3	6458 11170	16931	-1.809	-0.6124	Yes
75	PPP3CB	5285	16941	-1.823	-0.5995	Yes
76	PPP3CC	21763	16961	-1.850	-0.5869	Yes
77	ICAM1	19545	17130	-2.122	-0.5803	Yes
78	RAF1	17035	17131	-2.125	-0.5647	Yes
79	SOS2	21049	17328	-2.499	-0.5569	Yes
80	PRKCA	20174	17337	-2.525	-0.5387	Yes
81	IFNGR2	9155 22702	17428	-2.696	-0.5237	Yes
82	NFATC1	23398 1999 5167 9455 1985 1957	17449	-2.738	-0.5046	Yes
83	SH3BP2	16874	17547	-2.956	-0.4881	Yes
84	GRB2	20149	17590	-3.055	-0.4678	Yes
85	PLCG2	18453	17743	-3.480	-0.4504	Yes
86	NFATC3	5169	17772	-3.544	-0.4258	Yes
87	ICAM2	20183	18035	-4.385	-0.4077	Yes
88	SYK	21636	18074	-4.548	-0.3762	Yes
89	VAV1	23173	18136	-4.751	-0.3445	Yes
90	PRKCB1	1693 9574	18292	-5.486	-0.3125	Yes
91	PTK2B	21776	18298	-5.513	-0.2722	Yes
92	KRAS	9247	18396	-6.150	-0.2321	Yes
93	RAC2	22217	18467	-6.932	-0.1848	Yes
94	PTPN6	17002	18561	-8.216	-0.1293	Yes
95	PIK3CG	6635	18583	-8.846	-0.0653	Yes
96	MAPK1	1642 11167	18592	-9.104	0.0013	Yes