Details for gene set HSA04630_JAK_STAT_SIGNALING

Table: GSEA Results Summary

Dataset	Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB
Phenotype	phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	HSA04630_JAK_STAT_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.6847562
Normalized Enrichment Score (NES)	-1.7523284
Nominal p-value	0.0
FDR q-value	0.012235333
FWER p-Value	0.018

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SOCS2	5694	607	4.603	-0.0008	No
2	PIK3CB	19030	626	4.520	0.0297	No
3	CCND1	4487 4488 8707 17535	915	3.583	0.0391	No
4	PIK3R3	5248	1211	2.839	0.0429	No
5	IL12RB1	3916 18582	2185	1.330	-0.0005	No
6	STAM2	7095 2845	2969	0.582	-0.0388	No
7	IL2RB	22219	3089	0.502	-0.0417	No
8	SOCS3	20131	3325	0.381	-0.0518	No
9	PIK3R2	18850	3888	0.232	-0.0806	No
10	IL6ST	4920	3953	0.221	-0.0825	No
11	IL21R	1398 18084	4027	0.210	-0.0850	No
12	IL6R	1862 4919	4109	0.198	-0.0880	No
13	IFNA1	9147	4153	0.191	-0.0890	No
14	AKT1	8568	4218	0.183	-0.0912	No
15	SPRED2	8539 4332	4238	0.180	-0.0909	No
16	SOCS4	7424	4371	0.163	-0.0969	No
17	CNTF	3741 8761 3680 3736	4532	0.147	-0.1046	No
18	IL15	18826 3801	4605	0.140	-0.1075	No
19	IL4	9174	4886	0.119	-0.1218	No
20	IL5RA	17051	5098	0.107	-0.1325	No
21	IFNE1	15842	5117	0.106	-0.1327	No
22	IL24	976 13841	5125	0.106	-0.1324	No
23	IL15RA	2899 2717 15118 2792	5164	0.104	-0.1337	No
24	IL22RA2	20082	5529	0.085	-0.1528	No
25	IFNA7	9152	5600	0.082	-0.1560	No
26	CNTFR	2515 15906	5689	0.077	-0.1602	No
27	SPRY4	23448	5960	0.068	-0.1744	No
28	IL5	20884 10220	6018	0.066	-0.1770	No
29	LIF	956 667 20960	6074	0.064	-0.1795	No
30	SPRED1	4331	6232	0.060	-0.1876	No
31	TPO	21092	6363	0.056	-0.1942	No
32	AKT2	4365 4366	6728	0.048	-0.2136	No
33	IFNA14	11917	7024	0.042	-0.2293	No
34	IFNA6	17749	7067	0.041	-0.2313	No
35	IL19	13839	7097	0.040	-0.2326	No
36	IL12RB2	17128	7245	0.038	-0.2402	No
37	IL13	20461	7270	0.037	-0.2413	No
38	SOCS7	5308 20679	7277	0.037	-0.2414	No
39	STAT5B	20222	7325	0.036	-0.2436	No
40	IFNB1	15846	7388	0.035	-0.2468	No
41	IFNA2	9149	7465	0.033	-0.2506	No
42	IL9	21444	7562	0.032	-0.2556	No
43	IL10	14145 1510 1553 22902	7653	0.030	-0.2603	No
44	OSMR	22333	7777	0.028	-0.2667	No
45	MPL	15780	8264	0.021	-0.2929	No
46	IFNK	11837	8442	0.019	-0.3023	No
47	PIK3R5	11507	8444	0.019	-0.3022	No
48	IL2	15354	8580	0.017	-0.3094	No
49	IL28RA	10823 16038	9192	0.009	-0.3424	No
50	TSLP	23604 1955	9354	0.007	-0.3511	No
51	PTPN11	5326 16391 9660	9360	0.007	-0.3513	No
52	IL20	13840	9807	0.001	-0.3754	No
53	GHR	22336	9880	0.000	-0.3793	No
54	IL9R	20505	10012	-0.001	-0.3864	No
55	IL22	11948	10124	-0.002	-0.3924	No
56	CBLC	17938	10261	-0.004	-0.3997	No
57	IL23R	17127	10287	-0.004	-0.4010	No
58	IL13RA2	24036	10387	-0.006	-0.4064	No
59	IL12B	20918	10475	-0.007	-0.4110	No
60	IL6	16895	10534	-0.008	-0.4141	No
61	IFNA13	15844	11243	-0.018	-0.4523	No
62	IL22RA1	16037	11339	-0.019	-0.4573	No
63	CTF1	18064	11419	-0.020	-0.4614	No
64	IFNA4	9150	11609	-0.023	-0.4715	No
65	IL13RA1	24361	11611	-0.023	-0.4714	No
66	EPO	8911	11716	-0.025	-0.4768	No
67	SPRY2	21725	11811	-0.027	-0.4817	No
68	CSF3	1394 20671	11910	-0.028	-0.4868	No
69	IL11	17981	12040	-0.031	-0.4936	No
70	PRL	21690	12257	-0.036	-0.5050	No
71	SPRY1	15606 1901	12336	-0.037	-0.5090	No
72	PIK3R1	3170	12502	-0.041	-0.5176	No
73	IL3	20453	12731	-0.047	-0.5296	No
74	CSF2	20454	12732	-0.047	-0.5293	No
75	IL7	4921	12845	-0.050	-0.5350	No
76	IFNAR1	22703	12857	-0.050	-0.5353	No
77	LEP	17505	12936	-0.052	-0.5391	No
78	IL21	12241	12989	-0.054	-0.5416	No
79	SOS1	5476	13046	-0.056	-0.5442	No
80	LIFR	22515 9277	13248	-0.063	-0.5546	No
81	PIK3CA	9562	13540	-0.075	-0.5699	No
82	IL23A	19598	13736	-0.085	-0.5798	No
83	EPOR	19204	13811	-0.089	-0.5832	No
84	LEPR	2531 2349	13955	-0.099	-0.5903	No
85	PIAS2	1948 5102	14002	-0.102	-0.5920	No
86	IFNA5	9151	14080	-0.109	-0.5954	No
87	SOCS5	1619 23141	14532	-0.155	-0.6188	No
88	CBL	19154	14602	-0.166	-0.6213	No
89	IL2RG	24096	14876	-0.214	-0.6346	No
90	STAT4	14251 9907	15027	-0.245	-0.6410	No
91	STAT6	19854 9909	15032	-0.245	-0.6395	No
92	JAK2	23893 9197 3706	15111	-0.267	-0.6419	No
93	STAT5A	20664	15113	-0.268	-0.6401	No
94	IFNAR2	22705 1699	15148	-0.277	-0.6400	No
95	CSF3R	8804 8803 2326 4565	15159	-0.279	-0.6386	No
96	MYC	22465 9435	15334	-0.330	-0.6457	No
97	IL3RA	22091	15419	-0.360	-0.6478	No
98	IFNG	19869	15478	-0.380	-0.6483	No
99	PRLR	9620 5291	15588	-0.437	-0.6511	No
100	CLCF1	12160 3742	15636	-0.458	-0.6505	No
101	CRLF2	16442	15974	-0.692	-0.6639	No
102	JAK3	9198 4936	16361	-1.051	-0.6774	Yes
103	PIAS3	15491 672 1906	16377	-1.079	-0.6707	Yes
104	TYK2	12058 19215	16487	-1.199	-0.6683	Yes
105	IFNGR1	20083	16628	-1.403	-0.6661	Yes
106	STAM	2912 15117	16701	-1.509	-0.6595	Yes
107	PIK3CD	9563	16730	-1.548	-0.6502	Yes
108	JAK1	15827	16753	-1.590	-0.6403	Yes
109	AKT3	13739 982	16769	-1.612	-0.6299	Yes
110	PIAS4	19681	16872	-1.733	-0.6233	Yes
111	CCND2	16987	17025	-1.937	-0.6181	Yes
112	IL10RB	9169	17058	-1.990	-0.6059	Yes
113	CISH	8743	17238	-2.298	-0.5996	Yes
114	IL4R	18085	17294	-2.402	-0.5859	Yes
115	SOS2	21049	17328	-2.499	-0.5702	Yes
116	CSF2RA	23631	17346	-2.540	-0.5535	Yes
117	IFNGR2	9155 22702	17428	-2.696	-0.5391	Yes
118	PIM1	23308	17500	-2.869	-0.5229	Yes
119	STAT2	19840	17576	-3.019	-0.5060	Yes
120	GRB2	20149	17590	-3.055	-0.4854	Yes
121	IL2RA	4918	17622	-3.145	-0.4652	Yes
122	SOCS1	4522	17793	-3.598	-0.4493	Yes
123	CCND3	4489 4490	17924	-3.962	-0.4287	Yes
124	CREBBP	22682 8783	17993	-4.203	-0.4031	Yes
125	PIAS1	7126	18015	-4.270	-0.3745	Yes
126	IL10RA	19137	18152	-4.805	-0.3484	Yes
127	CBLB	5531 22734	18225	-5.154	-0.3164	Yes
128	STAT1	3936 5524	18294	-5.505	-0.2817	Yes
129	BCL2L1	4440 2930 8652	18337	-5.711	-0.2442	Yes
130	IL12A	4913	18393	-6.118	-0.2046	Yes
131	STAT3	5525 9906	18455	-6.760	-0.1608	Yes
132	IL7R	9175 4922	18493	-7.252	-0.1123	Yes
133	PTPN6	17002	18561	-8.216	-0.0587	Yes
134	PIK3CG	6635	18583	-8.846	0.0018	Yes