Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | WTpreB |
GeneSet | HSA04060_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION |
Enrichment Score (ES) | -0.6227177 |
Normalized Enrichment Score (NES) | -1.6827825 |
Nominal p-value | 0.0 |
FDR q-value | 0.031199064 |
FWER p-Value | 0.109 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | VEGFB | 23800 | 466 | 5.246 | 0.0170 | No | ||
2 | ACVR2B | 19276 | 1034 | 3.224 | 0.0121 | No | ||
3 | CSF1 | 15202 | 1896 | 1.677 | -0.0212 | No | ||
4 | TGFB2 | 5743 | 2083 | 1.454 | -0.0195 | No | ||
5 | IL12RB1 | 3916 18582 | 2185 | 1.330 | -0.0143 | No | ||
6 | CCL27 | 5419 | 3066 | 0.520 | -0.0580 | No | ||
7 | IL2RB | 22219 | 3089 | 0.502 | -0.0551 | No | ||
8 | IL18R1 | 14263 | 3136 | 0.468 | -0.0538 | No | ||
9 | VEGFA | 22969 | 3350 | 0.369 | -0.0624 | No | ||
10 | ACVR1 | 4334 | 3479 | 0.334 | -0.0667 | No | ||
11 | IL1R1 | 14264 3987 | 3542 | 0.316 | -0.0675 | No | ||
12 | TNFSF18 | 10789 6290 | 3736 | 0.265 | -0.0759 | No | ||
13 | CCL22 | 18518 | 3739 | 0.264 | -0.0739 | No | ||
14 | CXCL9 | 5099 | 3833 | 0.243 | -0.0769 | No | ||
15 | TNFRSF17 | 22856 | 3890 | 0.232 | -0.0781 | No | ||
16 | IL1B | 14431 | 3902 | 0.230 | -0.0769 | No | ||
17 | IL6ST | 4920 | 3953 | 0.221 | -0.0778 | No | ||
18 | IL21R | 1398 18084 | 4027 | 0.210 | -0.0801 | No | ||
19 | CXCL12 | 9792 1182 1031 | 4034 | 0.208 | -0.0787 | No | ||
20 | IL6R | 1862 4919 | 4109 | 0.198 | -0.0811 | No | ||
21 | IFNA1 | 9147 | 4153 | 0.191 | -0.0819 | No | ||
22 | AMHR2 | 8487 22345 | 4184 | 0.188 | -0.0821 | No | ||
23 | TNFRSF10B | 21971 10205 5781 10204 | 4210 | 0.184 | -0.0819 | No | ||
24 | CNTF | 3741 8761 3680 3736 | 4532 | 0.147 | -0.0982 | No | ||
25 | IL15 | 18826 3801 | 4605 | 0.140 | -0.1010 | No | ||
26 | XCR1 | 18953 | 4639 | 0.137 | -0.1017 | No | ||
27 | PPBP | 16801 | 4650 | 0.136 | -0.1011 | No | ||
28 | TNFRSF21 | 8244 | 4660 | 0.135 | -0.1005 | No | ||
29 | TNFSF13 | 12806 | 4662 | 0.135 | -0.0995 | No | ||
30 | LTBR | 16993 | 4882 | 0.120 | -0.1104 | No | ||
31 | IL4 | 9174 | 4886 | 0.119 | -0.1096 | No | ||
32 | IL5RA | 17051 | 5098 | 0.107 | -0.1202 | No | ||
33 | IFNE1 | 15842 | 5117 | 0.106 | -0.1203 | No | ||
34 | IL24 | 976 13841 | 5125 | 0.106 | -0.1199 | No | ||
35 | IL1A | 4915 | 5163 | 0.104 | -0.1210 | No | ||
36 | IL15RA | 2899 2717 15118 2792 | 5164 | 0.104 | -0.1202 | No | ||
37 | TNFRSF8 | 2373 5784 | 5242 | 0.099 | -0.1236 | No | ||
38 | FLT3 | 16288 | 5395 | 0.091 | -0.1311 | No | ||
39 | TNFSF13B | 6291 10792 | 5403 | 0.091 | -0.1308 | No | ||
40 | TNFSF10 | 15626 | 5420 | 0.090 | -0.1309 | No | ||
41 | TGFBR2 | 2994 3001 10167 | 5527 | 0.085 | -0.1360 | No | ||
42 | IL22RA2 | 20082 | 5529 | 0.085 | -0.1354 | No | ||
43 | PDGFC | 7048 | 5584 | 0.083 | -0.1376 | No | ||
44 | IFNA7 | 9152 | 5600 | 0.082 | -0.1378 | No | ||
45 | CNTFR | 2515 15906 | 5689 | 0.077 | -0.1420 | No | ||
46 | CCL24 | 16342 | 5732 | 0.075 | -0.1436 | No | ||
47 | CCL17 | 18517 | 5758 | 0.074 | -0.1444 | No | ||
48 | CSF1R | 8800 23540 | 5829 | 0.072 | -0.1476 | No | ||
49 | IL8RA | 13925 | 5863 | 0.071 | -0.1488 | No | ||
50 | CCR2 | 19250 | 5881 | 0.070 | -0.1492 | No | ||
51 | IL5 | 20884 10220 | 6018 | 0.066 | -0.1561 | No | ||
52 | LIF | 956 667 20960 | 6074 | 0.064 | -0.1585 | No | ||
53 | CCL5 | 20320 | 6118 | 0.063 | -0.1604 | No | ||
54 | KIT | 16823 | 6209 | 0.060 | -0.1648 | No | ||
55 | TPO | 21092 | 6363 | 0.056 | -0.1726 | No | ||
56 | CCR8 | 19272 | 6470 | 0.054 | -0.1780 | No | ||
57 | CCL1 | 9787 | 6578 | 0.051 | -0.1834 | No | ||
58 | CCL8 | 20740 | 6834 | 0.046 | -0.1969 | No | ||
59 | IL1R2 | 14265 | 6982 | 0.042 | -0.2045 | No | ||
60 | IFNA14 | 11917 | 7024 | 0.042 | -0.2064 | No | ||
61 | IFNA6 | 17749 | 7067 | 0.041 | -0.2083 | No | ||
62 | IL19 | 13839 | 7097 | 0.040 | -0.2096 | No | ||
63 | IL12RB2 | 17128 | 7245 | 0.038 | -0.2173 | No | ||
64 | EDAR | 19764 | 7249 | 0.038 | -0.2171 | No | ||
65 | IL13 | 20461 | 7270 | 0.037 | -0.2179 | No | ||
66 | XCL1 | 13781 | 7333 | 0.036 | -0.2210 | No | ||
67 | IFNB1 | 15846 | 7388 | 0.035 | -0.2237 | No | ||
68 | CCR9 | 8753 | 7390 | 0.035 | -0.2234 | No | ||
69 | MET | 17520 | 7434 | 0.034 | -0.2255 | No | ||
70 | IFNA2 | 9149 | 7465 | 0.033 | -0.2269 | No | ||
71 | CXCL16 | 7251 | 7494 | 0.033 | -0.2281 | No | ||
72 | IL9 | 21444 | 7562 | 0.032 | -0.2315 | No | ||
73 | IL10 | 14145 1510 1553 22902 | 7653 | 0.030 | -0.2362 | No | ||
74 | IL8RB | 8752 4533 | 7743 | 0.029 | -0.2408 | No | ||
75 | OSMR | 22333 | 7777 | 0.028 | -0.2423 | No | ||
76 | TNFRSF9 | 10208 5785 | 7947 | 0.026 | -0.2513 | No | ||
77 | GDF5 | 4768 | 8006 | 0.025 | -0.2543 | No | ||
78 | KDR | 16509 | 8027 | 0.024 | -0.2551 | No | ||
79 | CCL7 | 20743 | 8113 | 0.023 | -0.2596 | No | ||
80 | CCL3 | 20317 | 8171 | 0.022 | -0.2625 | No | ||
81 | PDGFRA | 16824 | 8178 | 0.022 | -0.2626 | No | ||
82 | PDGFB | 22199 2311 | 8207 | 0.022 | -0.2640 | No | ||
83 | MPL | 15780 | 8264 | 0.021 | -0.2669 | No | ||
84 | IL17A | 14289 | 8269 | 0.021 | -0.2669 | No | ||
85 | CD40LG | 24330 | 8297 | 0.020 | -0.2682 | No | ||
86 | IL25 | 22014 | 8440 | 0.019 | -0.2758 | No | ||
87 | IFNK | 11837 | 8442 | 0.019 | -0.2757 | No | ||
88 | ACVR2A | 8542 | 8474 | 0.018 | -0.2772 | No | ||
89 | IL2 | 15354 | 8580 | 0.017 | -0.2828 | No | ||
90 | CCR1 | 18951 | 8644 | 0.016 | -0.2861 | No | ||
91 | CX3CL1 | 9791 | 8684 | 0.015 | -0.2881 | No | ||
92 | IL28RA | 10823 16038 | 9192 | 0.009 | -0.3156 | No | ||
93 | INHBC | 19603 | 9351 | 0.007 | -0.3241 | No | ||
94 | TSLP | 23604 1955 | 9354 | 0.007 | -0.3242 | No | ||
95 | TNFSF12 | 10209 | 9371 | 0.007 | -0.3250 | No | ||
96 | CXCL14 | 21445 7165 | 9382 | 0.007 | -0.3255 | No | ||
97 | CXCL10 | 16477 | 9536 | 0.005 | -0.3337 | No | ||
98 | TNFRSF25 | 2334 15983 | 9571 | 0.004 | -0.3355 | No | ||
99 | EDA2R | 6364 | 9593 | 0.004 | -0.3367 | No | ||
100 | TNFSF9 | 23175 | 9690 | 0.003 | -0.3418 | No | ||
101 | CCL11 | 20742 | 9713 | 0.002 | -0.3430 | No | ||
102 | IL20 | 13840 | 9807 | 0.001 | -0.3481 | No | ||
103 | GHR | 22336 | 9880 | 0.000 | -0.3520 | No | ||
104 | TNFRSF11B | 22296 | 9893 | 0.000 | -0.3526 | No | ||
105 | FLT1 | 3483 16287 | 9989 | -0.001 | -0.3578 | No | ||
106 | IL9R | 20505 | 10012 | -0.001 | -0.3590 | No | ||
107 | IL22 | 11948 | 10124 | -0.002 | -0.3650 | No | ||
108 | CXCL11 | 16478 | 10254 | -0.004 | -0.3720 | No | ||
109 | IL23R | 17127 | 10287 | -0.004 | -0.3737 | No | ||
110 | TNFSF15 | 15863 | 10316 | -0.005 | -0.3751 | No | ||
111 | CCL4 | 1362 20730 | 10317 | -0.005 | -0.3751 | No | ||
112 | IL12B | 20918 | 10475 | -0.007 | -0.3836 | No | ||
113 | CCR5 | 8754 4534 | 10515 | -0.007 | -0.3856 | No | ||
114 | IL6 | 16895 | 10534 | -0.008 | -0.3866 | No | ||
115 | HGF | 16916 | 10648 | -0.009 | -0.3926 | No | ||
116 | TNFRSF11A | 14167 | 10773 | -0.011 | -0.3993 | No | ||
117 | TNFSF8 | 15862 | 11049 | -0.015 | -0.4141 | No | ||
118 | CCL2 | 9788 | 11156 | -0.016 | -0.4197 | No | ||
119 | CXCL5 | 16802 | 11222 | -0.017 | -0.4231 | No | ||
120 | IFNA13 | 15844 | 11243 | -0.018 | -0.4241 | No | ||
121 | IL22RA1 | 16037 | 11339 | -0.019 | -0.4291 | No | ||
122 | CXCR3 | 24093 | 11362 | -0.019 | -0.4301 | No | ||
123 | CTF1 | 18064 | 11419 | -0.020 | -0.4330 | No | ||
124 | CXCL2 | 9790 | 11463 | -0.021 | -0.4352 | No | ||
125 | IFNA4 | 9150 | 11609 | -0.023 | -0.4429 | No | ||
126 | IL13RA1 | 24361 | 11611 | -0.023 | -0.4427 | No | ||
127 | EPO | 8911 | 11716 | -0.025 | -0.4482 | No | ||
128 | CSF3 | 1394 20671 | 11910 | -0.028 | -0.4584 | No | ||
129 | IL11 | 17981 | 12040 | -0.031 | -0.4652 | No | ||
130 | EGF | 15169 | 12130 | -0.033 | -0.4698 | No | ||
131 | CCR3 | 19251 | 12158 | -0.033 | -0.4710 | No | ||
132 | INHBB | 13858 | 12235 | -0.035 | -0.4748 | No | ||
133 | PRL | 21690 | 12257 | -0.036 | -0.4757 | No | ||
134 | IL18RAP | 14262 | 12314 | -0.037 | -0.4784 | No | ||
135 | CCL19 | 10773 | 12316 | -0.037 | -0.4782 | No | ||
136 | BMP2 | 14833 | 12361 | -0.038 | -0.4803 | No | ||
137 | IL17B | 12074 | 12533 | -0.042 | -0.4892 | No | ||
138 | IL3 | 20453 | 12731 | -0.047 | -0.4996 | No | ||
139 | CSF2 | 20454 | 12732 | -0.047 | -0.4992 | No | ||
140 | IL7 | 4921 | 12845 | -0.050 | -0.5049 | No | ||
141 | IFNAR1 | 22703 | 12857 | -0.050 | -0.5050 | No | ||
142 | NGFR | 5174 | 12928 | -0.052 | -0.5084 | No | ||
143 | LEP | 17505 | 12936 | -0.052 | -0.5084 | No | ||
144 | IL17RB | 21898 | 12980 | -0.053 | -0.5103 | No | ||
145 | CD70 | 22916 | 12982 | -0.053 | -0.5099 | No | ||
146 | IL21 | 12241 | 12989 | -0.054 | -0.5098 | No | ||
147 | CXCR6 | 19252 | 12992 | -0.054 | -0.5095 | No | ||
148 | CX3CR1 | 18965 | 13065 | -0.056 | -0.5129 | No | ||
149 | LTA | 23003 | 13223 | -0.062 | -0.5210 | No | ||
150 | LIFR | 22515 9277 | 13248 | -0.063 | -0.5218 | No | ||
151 | FLT4 | 20904 1461 | 13357 | -0.067 | -0.5271 | No | ||
152 | PDGFRB | 23539 | 13453 | -0.070 | -0.5317 | No | ||
153 | CXCL13 | 16789 | 13488 | -0.072 | -0.5330 | No | ||
154 | BMPR1B | 8661 15152 4451 | 13550 | -0.076 | -0.5357 | No | ||
155 | TNF | 23004 | 13668 | -0.082 | -0.5414 | No | ||
156 | IL23A | 19598 | 13736 | -0.085 | -0.5443 | No | ||
157 | EPOR | 19204 | 13811 | -0.089 | -0.5476 | No | ||
158 | CCL25 | 9789 3848 | 13851 | -0.092 | -0.5490 | No | ||
159 | CCL28 | 7156 | 13854 | -0.092 | -0.5484 | No | ||
160 | KITLG | 19889 3342 | 13917 | -0.096 | -0.5510 | No | ||
161 | LEPR | 2531 2349 | 13955 | -0.099 | -0.5522 | No | ||
162 | TNFRSF4 | 15954 | 14017 | -0.103 | -0.5547 | No | ||
163 | INHBE | 19604 | 14060 | -0.107 | -0.5561 | No | ||
164 | BMP7 | 14324 | 14065 | -0.107 | -0.5555 | No | ||
165 | BMPR2 | 14241 4081 | 14078 | -0.109 | -0.5552 | No | ||
166 | IFNA5 | 9151 | 14080 | -0.109 | -0.5544 | No | ||
167 | TNFRSF1B | 5782 2346 | 14121 | -0.111 | -0.5557 | No | ||
168 | IL1RAP | 1653 1676 4917 1748 1712 9173 | 14193 | -0.119 | -0.5586 | No | ||
169 | BMPR1A | 8660 4450 | 14253 | -0.124 | -0.5608 | No | ||
170 | CD27 | 16994 | 14310 | -0.131 | -0.5628 | No | ||
171 | CXCL1 | 9044 | 14353 | -0.136 | -0.5640 | No | ||
172 | FASLG | 13789 | 14511 | -0.153 | -0.5713 | No | ||
173 | AMH | 19939 | 14541 | -0.156 | -0.5716 | No | ||
174 | EDA | 24284 | 14588 | -0.164 | -0.5728 | No | ||
175 | TNFSF11 | 21745 | 14594 | -0.165 | -0.5717 | No | ||
176 | TNFSF4 | 14082 | 14614 | -0.169 | -0.5714 | No | ||
177 | TGFBR1 | 16213 10165 5745 | 14646 | -0.174 | -0.5717 | No | ||
178 | TNFSF14 | 1584 22914 | 14665 | -0.178 | -0.5712 | No | ||
179 | ACVR1B | 4335 22353 | 14699 | -0.182 | -0.5715 | No | ||
180 | CCR4 | 18978 | 14852 | -0.210 | -0.5781 | No | ||
181 | IL2RG | 24096 | 14876 | -0.214 | -0.5776 | No | ||
182 | EGFR | 1329 20944 | 15017 | -0.243 | -0.5833 | No | ||
183 | IFNAR2 | 22705 1699 | 15148 | -0.277 | -0.5881 | No | ||
184 | CSF3R | 8804 8803 2326 4565 | 15159 | -0.279 | -0.5864 | No | ||
185 | IL3RA | 22091 | 15419 | -0.360 | -0.5976 | No | ||
186 | CCR6 | 1505 23390 | 15424 | -0.361 | -0.5949 | No | ||
187 | TNFRSF1A | 1181 10206 | 15447 | -0.370 | -0.5931 | No | ||
188 | CD40 | 10207 2961 2968 5783 | 15468 | -0.377 | -0.5912 | No | ||
189 | IFNG | 19869 | 15478 | -0.380 | -0.5886 | No | ||
190 | PRLR | 9620 5291 | 15588 | -0.437 | -0.5910 | No | ||
191 | CLCF1 | 12160 3742 | 15636 | -0.458 | -0.5899 | No | ||
192 | FAS | 23881 3750 | 15710 | -0.499 | -0.5898 | No | ||
193 | VEGFC | 10286 | 15812 | -0.558 | -0.5908 | No | ||
194 | PF4 | 16800 | 15825 | -0.571 | -0.5869 | No | ||
195 | TGFB3 | 10161 | 15913 | -0.649 | -0.5863 | No | ||
196 | CRLF2 | 16442 | 15974 | -0.692 | -0.5840 | No | ||
197 | TNFRSF12A | 23107 | 16381 | -1.087 | -0.5973 | No | ||
198 | IFNGR1 | 20083 | 16628 | -1.403 | -0.5994 | No | ||
199 | IL10RB | 9169 | 17058 | -1.990 | -0.6067 | Yes | ||
200 | IL17RA | 4914 | 17107 | -2.088 | -0.5925 | Yes | ||
201 | CCR7 | 20254 | 17123 | -2.114 | -0.5762 | Yes | ||
202 | IL4R | 18085 | 17294 | -2.402 | -0.5661 | Yes | ||
203 | CSF2RA | 23631 | 17346 | -2.540 | -0.5484 | Yes | ||
204 | TNFRSF14 | 15650 | 17403 | -2.649 | -0.5301 | Yes | ||
205 | IFNGR2 | 9155 22702 | 17428 | -2.696 | -0.5097 | Yes | ||
206 | TNFRSF18 | 15955 2394 | 17541 | -2.946 | -0.4920 | Yes | ||
207 | IL2RA | 4918 | 17622 | -3.145 | -0.4710 | Yes | ||
208 | TGFB1 | 18332 | 17722 | -3.435 | -0.4487 | Yes | ||
209 | IL10RA | 19137 | 18152 | -4.805 | -0.4333 | Yes | ||
210 | IL18 | 9172 | 18223 | -5.139 | -0.3957 | Yes | ||
211 | IL12A | 4913 | 18393 | -6.118 | -0.3556 | Yes | ||
212 | TNFRSF13B | 7181 | 18436 | -6.508 | -0.3054 | Yes | ||
213 | IL7R | 9175 4922 | 18493 | -7.252 | -0.2500 | Yes | ||
214 | LTB | 23259 | 18518 | -7.565 | -0.1904 | Yes | ||
215 | TNFRSF19 | 21799 3033 | 18537 | -7.831 | -0.1282 | Yes | ||
216 | CXCR4 | 13844 | 18551 | -7.968 | -0.0647 | Yes | ||
217 | TNFRSF13C | 22191 | 18568 | -8.463 | 0.0026 | Yes |