Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
| Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
| Upregulated in class | DMpreB |
| GeneSet | HSA00260_GLYCINE_SERINE_AND_THREONINE_METABOLISM |
| Enrichment Score (ES) | 0.6858597 |
| Normalized Enrichment Score (NES) | 1.4382371 |
| Nominal p-value | 0.04029304 |
| FDR q-value | 0.30466682 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PHGDH | 10675 | 50 | 9.414 | 0.1459 | Yes | ||
| 2 | SHMT1 | 5431 | 52 | 9.353 | 0.2935 | Yes | ||
| 3 | SHMT2 | 3307 19601 | 169 | 7.348 | 0.4032 | Yes | ||
| 4 | GARS | 17438 | 189 | 7.134 | 0.5148 | Yes | ||
| 5 | PSAT1 | 23718 3704 | 262 | 6.524 | 0.6139 | Yes | ||
| 6 | TARS | 22325 8502 | 745 | 4.119 | 0.6529 | Yes | ||
| 7 | GCAT | 11234 | 1220 | 2.828 | 0.6720 | Yes | ||
| 8 | PEMT | 20423 | 1865 | 1.731 | 0.6647 | Yes | ||
| 9 | SARS2 | 5 | 2163 | 1.359 | 0.6702 | Yes | ||
| 10 | HSD3B7 | 4158 | 2240 | 1.254 | 0.6859 | Yes | ||
| 11 | CBS | 1550 23034 | 3065 | 0.520 | 0.6497 | No | ||
| 12 | AOC2 | 20658 1256 | 3437 | 0.345 | 0.6352 | No | ||
| 13 | CHKA | 23759 | 3895 | 0.231 | 0.6142 | No | ||
| 14 | SDS | 16722 3582 | 4373 | 0.163 | 0.5911 | No | ||
| 15 | SARDH | 9646 | 4518 | 0.149 | 0.5857 | No | ||
| 16 | CTH | 1938 15131 | 5768 | 0.074 | 0.5197 | No | ||
| 17 | ABP1 | 17455 4598 | 5870 | 0.070 | 0.5153 | No | ||
| 18 | AOC3 | 8595 | 6410 | 0.055 | 0.4872 | No | ||
| 19 | AGXT | 14178 | 6938 | 0.043 | 0.4595 | No | ||
| 20 | GLDC | 23701 | 7673 | 0.030 | 0.4205 | No | ||
| 21 | MAOB | 24182 2556 | 7858 | 0.027 | 0.4110 | No | ||
| 22 | BHMT | 4446 | 8266 | 0.021 | 0.3894 | No | ||
| 23 | GNMT | 22955 | 8635 | 0.016 | 0.3699 | No | ||
| 24 | GAMT | 19698 | 9070 | 0.011 | 0.3467 | No | ||
| 25 | MAOA | 9368 24374 | 9570 | 0.004 | 0.3199 | No | ||
| 26 | DMGDH | 21585 | 9976 | -0.001 | 0.2981 | No | ||
| 27 | RDH13 | 17989 | 11929 | -0.029 | 0.1935 | No | ||
| 28 | PSPH | 16362 | 13573 | -0.077 | 0.1063 | No | ||
| 29 | GATM | 14451 | 13842 | -0.091 | 0.0933 | No | ||
| 30 | PIPOX | 20340 | 14001 | -0.102 | 0.0864 | No | ||
| 31 | AMT | 322 | 14832 | -0.205 | 0.0449 | No | ||
| 32 | CHDH | 5766 3440 | 15115 | -0.268 | 0.0340 | No | ||
| 33 | RDH14 | 21314 | 15216 | -0.293 | 0.0332 | No | ||
| 34 | ALAS1 | 19013 | 15909 | -0.642 | 0.0061 | No | ||
| 35 | ALAS2 | 24229 | 15987 | -0.706 | 0.0131 | No | ||
| 36 | RDH12 | 21227 | 16021 | -0.740 | 0.0230 | No | ||
| 37 | DLD | 2097 21090 | 16216 | -0.942 | 0.0274 | No | ||
| 38 | CHKB | 4518 | 16391 | -1.091 | 0.0353 | No | ||
| 39 | RDH11 | 21031 | 18262 | -5.350 | 0.0191 | No |
