Details for gene set HSA00230_PURINE

Table: GSEA Results Summary

Dataset	Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB
Phenotype	phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB
Upregulated in class	DMpreB
GeneSet	HSA00230_PURINE_METABOLISM
Enrichment Score (ES)	0.70083237
Normalized Enrichment Score (NES)	1.7443814
Nominal p-value	0.0
FDR q-value	0.003628531
FWER p-Value	0.0050

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	POLR1B	14857	6	11.186	0.0391	Yes
2	ATIC	14231 3968	53	9.237	0.0692	Yes
3	NME2	9468	56	9.099	0.1012	Yes
4	POLD2	20537	74	8.897	0.1316	Yes
5	IMPDH2	10730	85	8.592	0.1614	Yes
6	NME1	9467	97	8.436	0.1905	Yes
7	ADA	2703 14361	120	7.997	0.2175	Yes
8	PPAT	6081	124	7.966	0.2455	Yes
9	NUDT5	15121	125	7.938	0.2735	Yes
10	NME4	23065 1577	152	7.602	0.2989	Yes
11	GART	22543 1754	159	7.447	0.3248	Yes
12	ADSL	4358	162	7.442	0.3509	Yes
13	PDE6D	13897 3945	165	7.397	0.3769	Yes
14	NME6	3139 19297	233	6.695	0.3969	Yes
15	APRT	8620	239	6.668	0.4201	Yes
16	POLE	16755	244	6.625	0.4433	Yes
17	PAICS	16820	249	6.605	0.4663	Yes
18	GUK1	20432	253	6.591	0.4894	Yes
19	POLE3	7200	332	5.993	0.5063	Yes
20	RRM1	18163	384	5.624	0.5234	Yes
21	ENTPD4	7449	400	5.540	0.5421	Yes
22	GMPS	15578	404	5.492	0.5613	Yes
23	NUDT9	7897	532	4.903	0.5717	Yes
24	POLR2H	10888	611	4.591	0.5837	Yes
25	RFC5	13005 7791	625	4.526	0.5990	Yes
26	NT5M	8345 4175	648	4.452	0.6135	Yes
27	POLR2J	16672	654	4.444	0.6289	Yes
28	POLR2K	9413	663	4.410	0.6440	Yes
29	POLA2	23988	733	4.174	0.6550	Yes
30	PRPS1	24233	804	3.939	0.6651	Yes
31	NUDT2	16239	819	3.881	0.6780	Yes
32	POLR1D	3593 3658 16623	1115	3.040	0.6728	Yes
33	PRIM1	19847	1169	2.930	0.6802	Yes
34	PRPS2	24003	1345	2.528	0.6797	Yes
35	POLR3A	21900	1425	2.378	0.6838	Yes
36	PDE8A	18202	1491	2.260	0.6883	Yes
37	NP	22027 9597 5273 5274	1516	2.233	0.6948	Yes
38	POLR2I	12839	1549	2.195	0.7008	Yes
39	RRM2	5401 5400	1791	1.841	0.6943	No
40	POLD3	17742	1845	1.754	0.6976	No
41	POLR3H	13460 8135	1925	1.634	0.6991	No
42	IMPDH1	17197 1131	2099	1.444	0.6948	No
43	POLR2E	3325 19699	2210	1.298	0.6935	No
44	POLR3B	12875	2435	1.040	0.6850	No
45	POLR2G	23753	2511	0.997	0.6845	No
46	PNPT1	20936	2595	0.927	0.6832	No
47	NT5C3	17136	2639	0.878	0.6840	No
48	POLR2A	5394	2654	0.858	0.6863	No
49	ECGF1	22160	2820	0.712	0.6799	No
50	PDE10A	23387	3336	0.375	0.6533	No
51	AK3L1	8564	3394	0.355	0.6515	No
52	NT5E	19360 18702	3579	0.307	0.6426	No
53	ADCY3	21329 894	3959	0.220	0.6229	No
54	AK5	6042	4304	0.172	0.6049	No
55	ENTPD6	4496 2678	4439	0.157	0.5982	No
56	POLR1A	9749 5393	4612	0.140	0.5894	No
57	PDE5A	15431	5219	0.100	0.5570	No
58	PDE6G	20119	5337	0.094	0.5510	No
59	GUCY1A3	7216 12245 15310	5506	0.086	0.5422	No
60	NME7	926 4101 14070 3986 3946 931	5919	0.069	0.5202	No
61	AMPD2	1931 15197	6237	0.059	0.5032	No
62	RRM2B	6902 6903 11801	6260	0.059	0.5022	No
63	ENTPD1	4495	6425	0.055	0.4936	No
64	ENTPD3	19266	6629	0.051	0.4828	No
65	ADCY4	2980 21818	6720	0.048	0.4781	No
66	ENTPD8	12996	6753	0.047	0.4765	No
67	ENPP1	19804	6838	0.046	0.4721	No
68	PDE8B	5756	7062	0.041	0.4602	No
69	PDE1A	9541 5234	7443	0.034	0.4398	No
70	GUCY1A2	19580	7787	0.028	0.4213	No
71	XDH	22897	7802	0.028	0.4206	No
72	ALLC	21093 2130	8129	0.023	0.4031	No
73	POLR3K	12447 7372	8351	0.020	0.3912	No
74	GUCY2F	24045	8435	0.019	0.3868	No
75	AK1	4363	8516	0.018	0.3825	No
76	NPR1	9480	9200	0.009	0.3456	No
77	ADK	3302 3454 8555	9399	0.006	0.3349	No
78	GUCY1B3	15311	9545	0.005	0.3271	No
79	GDA	4764	9794	0.001	0.3137	No
80	POLA1	24112	9841	0.001	0.3112	No
81	PDE9A	23301	10122	-0.002	0.2961	No
82	ITPA	9193	10239	-0.004	0.2898	No
83	GUCY2C	1140 16954	10819	-0.012	0.2585	No
84	POLE2	21053	10899	-0.013	0.2543	No
85	PAPSS2	6258	11225	-0.017	0.2368	No
86	ENPP3	19803	11280	-0.018	0.2339	No
87	ADCY2	21412	11356	-0.019	0.2299	No
88	ADCY5	10312	11746	-0.026	0.2090	No
89	AMPD3	4383 2110	11809	-0.027	0.2057	No
90	POLR2B	16817	11867	-0.028	0.2027	No
91	ADCY8	22281	12049	-0.031	0.1931	No
92	PDE4A	3037 19542 3083 3023	12616	-0.045	0.1626	No
93	PKLR	1850 15545	12650	-0.046	0.1610	No
94	PDE1C	5235	12780	-0.048	0.1542	No
95	AMPD1	5051	12804	-0.049	0.1531	No
96	POLR2C	9750	12998	-0.054	0.1429	No
97	ENTPD2	8713	13167	-0.060	0.1340	No
98	PDE11A	10805	13180	-0.060	0.1335	No
99	ADCY6	22139 2283 8551	13201	-0.061	0.1327	No
100	PDE7B	19807	13459	-0.071	0.1190	No
101	NPR2	16230	13552	-0.076	0.1143	No
102	PDE3B	5236	14073	-0.108	0.0866	No
103	PDE6H	17257	14320	-0.132	0.0737	No
104	NT5C1B	21315	14351	-0.135	0.0726	No
105	PKM2	3642 9573	14550	-0.157	0.0624	No
106	CANT1	13304	14576	-0.162	0.0617	No
107	PDE2A	18170	15025	-0.244	0.0383	No
108	GMPR2	2711	15528	-0.409	0.0126	No
109	PDE4B	9543	15644	-0.464	0.0080	No
110	PDE4C	8481	15712	-0.501	0.0061	No
111	HPRT1	2655 24339 408	15918	-0.652	-0.0027	No
112	PDE4D	10722 6235	15934	-0.668	-0.0011	No
113	FHIT	21920	16018	-0.738	-0.0030	No
114	ADCY9	22680	16343	-1.039	-0.0169	No
115	ADCY7	8552 448	16398	-1.096	-0.0159	No
116	PAPSS1	15419	16426	-1.129	-0.0134	No
117	GMPR	21651	16589	-1.333	-0.0175	No
118	DGUOK	17099 1041	16593	-1.342	-0.0129	No
119	NT5C	20151	16823	-1.699	-0.0193	No
120	NT5C2	3768 8052	17022	-1.933	-0.0232	No
121	ADSSL1	21136 2087	17188	-2.229	-0.0243	No
122	POLE4	12441	17259	-2.349	-0.0198	No
123	ZNRD1	1491 22987	17280	-2.385	-0.0124	No
124	ENTPD5	4497	17367	-2.586	-0.0080	No
125	POLD1	17847	17439	-2.709	-0.0023	No
126	AK2	8563 2479 16073	17761	-3.520	-0.0072	No
127	PDE7A	9544 1788	17861	-3.771	0.0007	No
128	DCK	16808	17923	-3.959	0.0114	No
129	POLD4	12822	18505	-7.381	0.0060	No