Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
| Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
| Upregulated in class | DMpreB |
| GeneSet | DNA_REPLICATION_REACTOME |
| Enrichment Score (ES) | 0.7661158 |
| Normalized Enrichment Score (NES) | 1.5971588 |
| Nominal p-value | 0.0037105752 |
| FDR q-value | 0.07684547 |
| FWER p-Value | 0.365 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | POLD2 | 20537 | 74 | 8.897 | 0.0667 | Yes | ||
| 2 | NACA | 9444 5147 | 205 | 6.962 | 0.1150 | Yes | ||
| 3 | ORC6L | 18539 | 227 | 6.751 | 0.1674 | Yes | ||
| 4 | POLE | 16755 | 244 | 6.625 | 0.2192 | Yes | ||
| 5 | RFC1 | 16527 | 335 | 5.989 | 0.2619 | Yes | ||
| 6 | MCM3 | 13991 | 390 | 5.583 | 0.3033 | Yes | ||
| 7 | PRIM2A | 13986 | 419 | 5.409 | 0.3448 | Yes | ||
| 8 | MCM7 | 9372 3568 | 497 | 5.089 | 0.3810 | Yes | ||
| 9 | MCM10 | 14694 | 573 | 4.728 | 0.4146 | Yes | ||
| 10 | RFC4 | 1735 22627 | 589 | 4.674 | 0.4509 | Yes | ||
| 11 | MCM2 | 17074 | 598 | 4.627 | 0.4872 | Yes | ||
| 12 | RFC5 | 13005 7791 | 625 | 4.526 | 0.5217 | Yes | ||
| 13 | RFC3 | 12786 | 722 | 4.193 | 0.5499 | Yes | ||
| 14 | POLA2 | 23988 | 733 | 4.174 | 0.5825 | Yes | ||
| 15 | RPA1 | 20349 | 739 | 4.140 | 0.6151 | Yes | ||
| 16 | GMNN | 21513 | 848 | 3.827 | 0.6397 | Yes | ||
| 17 | ORC5L | 11173 3595 | 924 | 3.572 | 0.6640 | Yes | ||
| 18 | RPA3 | 12667 | 963 | 3.441 | 0.6893 | Yes | ||
| 19 | MCM5 | 18564 | 1005 | 3.303 | 0.7133 | Yes | ||
| 20 | PCNA | 9535 | 1100 | 3.074 | 0.7326 | Yes | ||
| 21 | PRIM1 | 19847 | 1169 | 2.930 | 0.7522 | Yes | ||
| 22 | CDT1 | 18437 | 1380 | 2.457 | 0.7605 | Yes | ||
| 23 | POLD3 | 17742 | 1845 | 1.754 | 0.7494 | Yes | ||
| 24 | CDK2 | 3438 3373 19592 3322 | 1846 | 1.753 | 0.7633 | Yes | ||
| 25 | RPA2 | 2330 16057 | 2021 | 1.531 | 0.7661 | Yes | ||
| 26 | UBC | 14 14 10241 15 16 | 2761 | 0.757 | 0.7323 | No | ||
| 27 | UBB | 10240 | 3059 | 0.522 | 0.7205 | No | ||
| 28 | ORC3L | 6941 | 3209 | 0.437 | 0.7160 | No | ||
| 29 | UBA52 | 10239 | 3957 | 0.221 | 0.6775 | No | ||
| 30 | ORC4L | 11172 6460 | 4035 | 0.208 | 0.6750 | No | ||
| 31 | MCM4 | 22655 1708 | 4196 | 0.186 | 0.6679 | No | ||
| 32 | CDC6 | 6221 6220 | 6125 | 0.063 | 0.5646 | No | ||
| 33 | CDC45L | 22642 1752 | 9951 | -0.001 | 0.3587 | No | ||
| 34 | POLE2 | 21053 | 10899 | -0.013 | 0.3078 | No | ||
| 35 | ORC2L | 385 13949 | 14740 | -0.190 | 0.1026 | No | ||
| 36 | RPS27A | 13433 | 15293 | -0.318 | 0.0754 | No | ||
| 37 | ORC1L | 327 16144 | 15837 | -0.579 | 0.0508 | No | ||
| 38 | MCM6 | 4000 13845 4119 | 15865 | -0.608 | 0.0541 | No | ||
| 39 | CDC7 | 16765 3477 | 16851 | -1.722 | 0.0148 | No | ||
| 40 | POLD1 | 17847 | 17439 | -2.709 | 0.0047 | No | ||
| 41 | POLD4 | 12822 | 18505 | -7.381 | 0.0060 | No |
