Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
| Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
| Upregulated in class | DMpreB |
| GeneSet | REACTOME_PURINE_METABOLISM |
| Enrichment Score (ES) | 0.8046084 |
| Normalized Enrichment Score (NES) | 1.6844394 |
| Nominal p-value | 0.0017889087 |
| FDR q-value | 0.005830615 |
| FWER p-Value | 0.087 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ATIC | 14231 3968 | 53 | 9.237 | 0.0650 | Yes | ||
| 2 | NME2 | 9468 | 56 | 9.099 | 0.1318 | Yes | ||
| 3 | IMPDH2 | 10730 | 85 | 8.592 | 0.1935 | Yes | ||
| 4 | ATP5G1 | 8636 | 95 | 8.444 | 0.2551 | Yes | ||
| 5 | NME1 | 9467 | 97 | 8.436 | 0.3170 | Yes | ||
| 6 | ADA | 2703 14361 | 120 | 7.997 | 0.3746 | Yes | ||
| 7 | PPAT | 6081 | 124 | 7.966 | 0.4330 | Yes | ||
| 8 | GART | 22543 1754 | 159 | 7.447 | 0.4859 | Yes | ||
| 9 | ADSL | 4358 | 162 | 7.442 | 0.5405 | Yes | ||
| 10 | APRT | 8620 | 239 | 6.668 | 0.5854 | Yes | ||
| 11 | PAICS | 16820 | 249 | 6.605 | 0.6335 | Yes | ||
| 12 | GUK1 | 20432 | 253 | 6.591 | 0.6818 | Yes | ||
| 13 | RRM1 | 18163 | 384 | 5.624 | 0.7161 | Yes | ||
| 14 | GMPS | 15578 | 404 | 5.492 | 0.7555 | Yes | ||
| 15 | ATP5J2 | 12186 | 976 | 3.393 | 0.7497 | Yes | ||
| 16 | ATP5I | 8637 | 1084 | 3.109 | 0.7668 | Yes | ||
| 17 | ATP5O | 22539 | 1183 | 2.898 | 0.7828 | Yes | ||
| 18 | ATP5A1 | 23505 | 1292 | 2.659 | 0.7965 | Yes | ||
| 19 | NP | 22027 9597 5273 5274 | 1516 | 2.233 | 0.8010 | Yes | ||
| 20 | RRM2 | 5401 5400 | 1791 | 1.841 | 0.7997 | Yes | ||
| 21 | ATP5H | 12948 | 2079 | 1.460 | 0.7950 | Yes | ||
| 22 | IMPDH1 | 17197 1131 | 2099 | 1.444 | 0.8046 | Yes | ||
| 23 | ATP5J | 880 22555 | 2469 | 1.011 | 0.7922 | No | ||
| 24 | ATP5E | 14321 | 2497 | 0.999 | 0.7981 | No | ||
| 25 | ATP5F1 | 15212 | 2606 | 0.908 | 0.7989 | No | ||
| 26 | TXNRD1 | 19923 | 2783 | 0.740 | 0.7949 | No | ||
| 27 | ATP5D | 19949 | 3095 | 0.499 | 0.7818 | No | ||
| 28 | AMPD2 | 1931 15197 | 6237 | 0.059 | 0.6132 | No | ||
| 29 | XDH | 22897 | 7802 | 0.028 | 0.5292 | No | ||
| 30 | AK1 | 4363 | 8516 | 0.018 | 0.4910 | No | ||
| 31 | ADK | 3302 3454 8555 | 9399 | 0.006 | 0.4435 | No | ||
| 32 | AMPD3 | 4383 2110 | 11809 | -0.027 | 0.3141 | No | ||
| 33 | AMPD1 | 5051 | 12804 | -0.049 | 0.2609 | No | ||
| 34 | ATP5B | 19846 | 14988 | -0.238 | 0.1452 | No | ||
| 35 | ATP5C1 | 8635 | 15887 | -0.627 | 0.1014 | No | ||
| 36 | HPRT1 | 2655 24339 408 | 15918 | -0.652 | 0.1046 | No | ||
| 37 | DGUOK | 17099 1041 | 16593 | -1.342 | 0.0782 | No | ||
| 38 | NT5C2 | 3768 8052 | 17022 | -1.933 | 0.0694 | No | ||
| 39 | ADSSL1 | 21136 2087 | 17188 | -2.229 | 0.0769 | No |
