Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | DMpreB |
GeneSet | REACTOME_GENE_EXPRESSION |
Enrichment Score (ES) | 0.72053075 |
Normalized Enrichment Score (NES) | 1.7970748 |
Nominal p-value | 0.0 |
FDR q-value | 8.2068966E-4 |
FWER p-Value | 0.0010 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | EIF4A1 | 8889 23719 | 80 | 8.676 | 0.0246 | Yes | ||
2 | NUP43 | 20094 | 90 | 8.530 | 0.0525 | Yes | ||
3 | RARS | 20496 | 112 | 8.069 | 0.0783 | Yes | ||
4 | EEF1E1 | 21488 | 139 | 7.768 | 0.1027 | Yes | ||
5 | GARS | 17438 | 189 | 7.134 | 0.1239 | Yes | ||
6 | NUPL2 | 6072 | 203 | 6.986 | 0.1464 | Yes | ||
7 | ETF1 | 23467 | 265 | 6.495 | 0.1648 | Yes | ||
8 | NUP93 | 7762 | 280 | 6.335 | 0.1851 | Yes | ||
9 | CPSF1 | 22241 | 298 | 6.229 | 0.2050 | Yes | ||
10 | SFRS6 | 14751 | 326 | 6.012 | 0.2235 | Yes | ||
11 | U2AF1 | 8431 | 346 | 5.954 | 0.2423 | Yes | ||
12 | EIF2B1 | 16368 3458 | 368 | 5.739 | 0.2603 | Yes | ||
13 | RAE1 | 12395 | 381 | 5.644 | 0.2785 | Yes | ||
14 | RDBP | 6589 | 428 | 5.370 | 0.2939 | Yes | ||
15 | SNRPD2 | 8412 | 436 | 5.355 | 0.3114 | Yes | ||
16 | GTF2H3 | 5551 | 477 | 5.199 | 0.3265 | Yes | ||
17 | SF3B3 | 18746 | 507 | 5.015 | 0.3417 | Yes | ||
18 | RPL38 | 12562 20606 7475 | 515 | 4.983 | 0.3579 | Yes | ||
19 | SNRPF | 7645 | 541 | 4.871 | 0.3728 | Yes | ||
20 | EEF1G | 12480 | 547 | 4.848 | 0.3886 | Yes | ||
21 | EIF4G1 | 22818 | 582 | 4.708 | 0.4025 | Yes | ||
22 | RPS24 | 5399 | 584 | 4.691 | 0.4181 | Yes | ||
23 | POLR2H | 10888 | 611 | 4.591 | 0.4320 | Yes | ||
24 | LARS2 | 19255 | 629 | 4.507 | 0.4461 | Yes | ||
25 | SNRPG | 12622 | 632 | 4.487 | 0.4609 | Yes | ||
26 | POLR2J | 16672 | 654 | 4.444 | 0.4746 | Yes | ||
27 | RPS2 | 9279 | 710 | 4.232 | 0.4857 | Yes | ||
28 | SF3A3 | 16091 | 711 | 4.229 | 0.4998 | Yes | ||
29 | RPL14 | 19267 | 713 | 4.224 | 0.5138 | Yes | ||
30 | NARS | 23418 | 715 | 4.220 | 0.5278 | Yes | ||
31 | PHF5A | 22194 | 738 | 4.141 | 0.5404 | Yes | ||
32 | RPLP2 | 7401 | 825 | 3.870 | 0.5487 | Yes | ||
33 | SFRS3 | 5428 23312 | 850 | 3.817 | 0.5601 | Yes | ||
34 | MAGOH | 2386 16148 | 921 | 3.574 | 0.5682 | Yes | ||
35 | RPL27A | 11181 6467 18130 | 948 | 3.476 | 0.5784 | Yes | ||
36 | PRPF4 | 7655 12845 | 949 | 3.476 | 0.5900 | Yes | ||
37 | CSTF1 | 12515 | 954 | 3.455 | 0.6013 | Yes | ||
38 | RPS19 | 5398 | 1114 | 3.041 | 0.6028 | Yes | ||
39 | RPL4 | 7499 19411 | 1205 | 2.853 | 0.6074 | Yes | ||
40 | DNAJC8 | 12712 | 1329 | 2.559 | 0.6093 | Yes | ||
41 | GTF2H2 | 6236 | 1365 | 2.487 | 0.6157 | Yes | ||
42 | YBX1 | 5929 2389 | 1376 | 2.461 | 0.6233 | Yes | ||
43 | TCEB1 | 13995 | 1381 | 2.456 | 0.6313 | Yes | ||
44 | NUP62 | 9497 | 1445 | 2.341 | 0.6357 | Yes | ||
45 | CCNH | 7322 | 1482 | 2.274 | 0.6413 | Yes | ||
46 | POLR2I | 12839 | 1549 | 2.195 | 0.6451 | Yes | ||
47 | GTF2E2 | 18635 | 1569 | 2.165 | 0.6512 | Yes | ||
48 | PTBP1 | 5303 | 1596 | 2.132 | 0.6569 | Yes | ||
49 | PRPF8 | 20780 1371 | 1640 | 2.062 | 0.6615 | Yes | ||
50 | EIF5 | 5736 | 1642 | 2.062 | 0.6683 | Yes | ||
51 | RPL6 | 9747 | 1668 | 2.029 | 0.6737 | Yes | ||
52 | RNMT | 7501 | 1694 | 1.984 | 0.6790 | Yes | ||
53 | EIF2S2 | 7406 14383 | 1803 | 1.829 | 0.6792 | Yes | ||
54 | TH1L | 14715 | 1809 | 1.820 | 0.6850 | Yes | ||
55 | NUP160 | 14957 | 1842 | 1.755 | 0.6891 | Yes | ||
56 | EIF4B | 13279 7979 | 1871 | 1.716 | 0.6933 | Yes | ||
57 | RPS23 | 12352 | 1923 | 1.642 | 0.6960 | Yes | ||
58 | CCAR1 | 7454 | 1939 | 1.606 | 0.7006 | Yes | ||
59 | TBP | 671 1554 | 1943 | 1.603 | 0.7058 | Yes | ||
60 | RANBP2 | 20019 | 2017 | 1.536 | 0.7069 | Yes | ||
61 | SFRS1 | 8492 | 2072 | 1.466 | 0.7089 | Yes | ||
62 | SF3B2 | 23974 | 2176 | 1.345 | 0.7078 | Yes | ||
63 | POLR2E | 3325 19699 | 2210 | 1.298 | 0.7103 | Yes | ||
64 | ERCC3 | 23605 | 2238 | 1.255 | 0.7130 | Yes | ||
65 | SFRS9 | 16731 | 2268 | 1.221 | 0.7155 | Yes | ||
66 | TAF11 | 12733 | 2390 | 1.069 | 0.7126 | Yes | ||
67 | SFRS7 | 22889 | 2416 | 1.053 | 0.7147 | Yes | ||
68 | RARS2 | 16247 2490 2411 | 2503 | 0.998 | 0.7134 | Yes | ||
69 | NFX1 | 2475 | 2552 | 0.972 | 0.7140 | Yes | ||
70 | NUDT21 | 12665 | 2612 | 0.905 | 0.7138 | Yes | ||
71 | POLR2A | 5394 | 2654 | 0.858 | 0.7145 | Yes | ||
72 | SF3A2 | 19938 | 2677 | 0.837 | 0.7161 | Yes | ||
73 | EIF2B2 | 21204 | 2693 | 0.823 | 0.7180 | Yes | ||
74 | MED6 | 21028 | 2728 | 0.788 | 0.7188 | Yes | ||
75 | CCNC | 16263 | 2777 | 0.745 | 0.7187 | Yes | ||
76 | SFRS2 | 9807 20136 | 2789 | 0.733 | 0.7205 | Yes | ||
77 | SFRS5 | 9808 2062 | 2896 | 0.639 | 0.7169 | No | ||
78 | RPS15A | 6476 | 2968 | 0.585 | 0.7150 | No | ||
79 | TAF12 | 2537 16058 2338 | 3042 | 0.532 | 0.7128 | No | ||
80 | RPS3A | 9755 | 3073 | 0.515 | 0.7129 | No | ||
81 | EEF2 | 8881 4654 8882 | 3263 | 0.412 | 0.7041 | No | ||
82 | SNW1 | 7282 | 3362 | 0.365 | 0.7000 | No | ||
83 | RPL41 | 12611 | 3691 | 0.275 | 0.6832 | No | ||
84 | IARS | 4190 8361 8362 | 3823 | 0.247 | 0.6769 | No | ||
85 | YARS | 16071 | 3945 | 0.223 | 0.6711 | No | ||
86 | SUPT4H1 | 9938 | 3948 | 0.222 | 0.6717 | No | ||
87 | WARS | 2085 20984 | 3955 | 0.221 | 0.6721 | No | ||
88 | RPL8 | 22437 | 4060 | 0.205 | 0.6672 | No | ||
89 | GTF2H1 | 4069 18236 | 4080 | 0.203 | 0.6668 | No | ||
90 | SNRPB | 9842 5469 2736 | 4208 | 0.184 | 0.6606 | No | ||
91 | RPL27 | 9740 | 4251 | 0.178 | 0.6589 | No | ||
92 | TAF9 | 3213 8433 | 4594 | 0.141 | 0.6408 | No | ||
93 | DHX9 | 8845 4608 3948 | 4843 | 0.122 | 0.6278 | No | ||
94 | RPL19 | 9736 | 4895 | 0.119 | 0.6254 | No | ||
95 | EIF2S1 | 4658 | 4969 | 0.114 | 0.6219 | No | ||
96 | NUP35 | 12803 | 6597 | 0.051 | 0.5340 | No | ||
97 | GTF2A2 | 10654 | 6734 | 0.048 | 0.5268 | No | ||
98 | RPL18 | 450 5390 | 7540 | 0.032 | 0.4833 | No | ||
99 | EIF4E | 15403 1827 8890 | 7583 | 0.031 | 0.4811 | No | ||
100 | TAF4 | 14319 | 8745 | 0.015 | 0.4183 | No | ||
101 | TPR | 927 4255 | 8987 | 0.012 | 0.4053 | No | ||
102 | NUP153 | 21474 | 9407 | 0.006 | 0.3826 | No | ||
103 | RPL17 | 11429 6653 | 9669 | 0.003 | 0.3685 | No | ||
104 | CDK7 | 21365 | 9956 | -0.001 | 0.3530 | No | ||
105 | CCNT2 | 3993 13079 | 10873 | -0.012 | 0.3035 | No | ||
106 | POLR2B | 16817 | 11867 | -0.028 | 0.2498 | No | ||
107 | RPS13 | 12633 | 11876 | -0.028 | 0.2495 | No | ||
108 | RNPS1 | 9730 23361 | 12295 | -0.036 | 0.2270 | No | ||
109 | HARS | 23451 | 12413 | -0.039 | 0.2208 | No | ||
110 | EIF5B | 10391 5963 | 12946 | -0.053 | 0.1922 | No | ||
111 | POLR2C | 9750 | 12998 | -0.054 | 0.1896 | No | ||
112 | EPRS | 14014 | 13018 | -0.055 | 0.1887 | No | ||
113 | SNRPB2 | 5470 | 13068 | -0.056 | 0.1863 | No | ||
114 | RPS16 | 9752 | 14531 | -0.155 | 0.1076 | No | ||
115 | RPS5 | 18391 | 14818 | -0.203 | 0.0928 | No | ||
116 | SF3B1 | 13954 | 14840 | -0.208 | 0.0924 | No | ||
117 | RPL5 | 9746 | 14950 | -0.227 | 0.0872 | No | ||
118 | U2AF2 | 5813 5812 5814 | 15014 | -0.242 | 0.0846 | No | ||
119 | FAU | 8954 | 15042 | -0.247 | 0.0840 | No | ||
120 | RPS29 | 9754 | 15047 | -0.248 | 0.0846 | No | ||
121 | METTL3 | 21841 | 15104 | -0.265 | 0.0825 | No | ||
122 | SMC1A | 2572 24225 6279 10780 | 15233 | -0.298 | 0.0765 | No | ||
123 | SF3B4 | 22269 | 15268 | -0.309 | 0.0757 | No | ||
124 | FARS2 | 21666 | 15351 | -0.335 | 0.0724 | No | ||
125 | NUP54 | 11231 11232 6516 | 15488 | -0.387 | 0.0663 | No | ||
126 | RNGTT | 10769 2354 6272 | 15504 | -0.396 | 0.0668 | No | ||
127 | RPL28 | 5392 | 15723 | -0.504 | 0.0567 | No | ||
128 | RPL18A | 13358 | 15815 | -0.562 | 0.0536 | No | ||
129 | RPS21 | 12356 | 15832 | -0.577 | 0.0547 | No | ||
130 | RPLP1 | 3010 | 15852 | -0.591 | 0.0556 | No | ||
131 | RPS20 | 7438 | 15960 | -0.687 | 0.0521 | No | ||
132 | EIF4EBP1 | 8891 4661 | 15963 | -0.688 | 0.0543 | No | ||
133 | RPS28 | 12009 | 15976 | -0.693 | 0.0560 | No | ||
134 | RPL37A | 9744 | 15994 | -0.712 | 0.0574 | No | ||
135 | TXNL4A | 6567 11329 | 16111 | -0.840 | 0.0540 | No | ||
136 | RBM5 | 13507 3016 | 16304 | -1.004 | 0.0469 | No | ||
137 | RPL11 | 12450 | 16403 | -1.103 | 0.0453 | No | ||
138 | CCNT1 | 22140 11607 | 16429 | -1.133 | 0.0477 | No | ||
139 | GTF2B | 10489 | 16476 | -1.194 | 0.0492 | No | ||
140 | ELL | 18586 | 16902 | -1.772 | 0.0321 | No | ||
141 | AARS | 10630 6151 | 16973 | -1.862 | 0.0345 | No | ||
142 | SRRM1 | 6958 | 17048 | -1.978 | 0.0371 | No | ||
143 | TAF10 | 10785 | 17301 | -2.423 | 0.0315 | No | ||
144 | CD2BP2 | 17621 | 17506 | -2.877 | 0.0301 | No | ||
145 | SNRPA1 | 1373 18216 | 18588 | -8.994 | 0.0015 | No |