Dataset | Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB |
Phenotype | phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB |
Upregulated in class | WTpreB |
GeneSet | NETPATH_BCR |
Enrichment Score (ES) | -0.6711106 |
Normalized Enrichment Score (NES) | -1.7111392 |
Nominal p-value | 0.0 |
FDR q-value | 0.011120569 |
FWER p-Value | 0.086 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PTK2 | 22271 | 13 | 10.897 | 0.0410 | No | ||
2 | DOK3 | 3229 21451 | 207 | 6.945 | 0.0571 | No | ||
3 | CCNE1 | 17857 | 261 | 6.545 | 0.0792 | No | ||
4 | BAX | 17832 | 644 | 4.463 | 0.0757 | No | ||
5 | CYCS | 8821 | 744 | 4.120 | 0.0861 | No | ||
6 | MAP3K7 | 16255 | 1398 | 2.420 | 0.0600 | No | ||
7 | MAPK8 | 6459 | 1644 | 2.061 | 0.0547 | No | ||
8 | RPS6 | 9757 | 1729 | 1.922 | 0.0575 | No | ||
9 | BLNK | 23681 3691 | 1758 | 1.877 | 0.0631 | No | ||
10 | CDK2 | 3438 3373 19592 3322 | 1846 | 1.753 | 0.0651 | No | ||
11 | CHUK | 23665 | 2157 | 1.372 | 0.0536 | No | ||
12 | BCAR1 | 18741 | 2225 | 1.277 | 0.0549 | No | ||
13 | CCNA2 | 15357 | 2301 | 1.176 | 0.0553 | No | ||
14 | PPP3CA | 1863 5284 | 2520 | 0.993 | 0.0473 | No | ||
15 | IKBKB | 4907 | 2775 | 0.746 | 0.0365 | No | ||
16 | BCL2L11 | 2790 14861 | 3193 | 0.445 | 0.0156 | No | ||
17 | CDK4 | 3424 19859 | 3277 | 0.401 | 0.0127 | No | ||
18 | CDK6 | 16600 | 3557 | 0.311 | -0.0012 | No | ||
19 | PIK3R2 | 18850 | 3888 | 0.232 | -0.0182 | No | ||
20 | SHC1 | 9813 9812 5430 | 3936 | 0.225 | -0.0198 | No | ||
21 | AKT1 | 8568 | 4218 | 0.183 | -0.0343 | No | ||
22 | BCL2 | 8651 3928 13864 4435 981 4062 13863 4027 | 4380 | 0.162 | -0.0424 | No | ||
23 | FYN | 3375 3395 20052 | 5072 | 0.109 | -0.0793 | No | ||
24 | ITK | 4934 | 5197 | 0.102 | -0.0857 | No | ||
25 | CD5 | 23741 | 5231 | 0.100 | -0.0871 | No | ||
26 | ACTR3 | 13166 | 7078 | 0.041 | -0.1867 | No | ||
27 | MAPK4 | 23409 | 7547 | 0.032 | -0.2119 | No | ||
28 | NCK1 | 9447 5152 | 7819 | 0.028 | -0.2264 | No | ||
29 | PRKCE | 9575 | 7915 | 0.026 | -0.2314 | No | ||
30 | PTPN11 | 5326 16391 9660 | 9360 | 0.007 | -0.3095 | No | ||
31 | ACTR2 | 20523 | 9444 | 0.006 | -0.3139 | No | ||
32 | CDK7 | 21365 | 9956 | -0.001 | -0.3415 | No | ||
33 | LYN | 16281 | 10463 | -0.007 | -0.3689 | No | ||
34 | CR2 | 3942 13707 | 10585 | -0.008 | -0.3754 | No | ||
35 | RPS6KA1 | 15725 | 10766 | -0.011 | -0.3850 | No | ||
36 | PPP3R1 | 9611 489 | 11661 | -0.024 | -0.4333 | No | ||
37 | NFATC2 | 5168 2866 | 11816 | -0.027 | -0.4415 | No | ||
38 | IKBKG | 2570 2562 4908 | 11885 | -0.028 | -0.4451 | No | ||
39 | DOK1 | 17104 1018 1177 | 12045 | -0.031 | -0.4535 | No | ||
40 | DAPP1 | 11159 6445 6446 | 12268 | -0.036 | -0.4654 | No | ||
41 | PIK3R1 | 3170 | 12502 | -0.041 | -0.4778 | No | ||
42 | GAB2 | 1821 18184 2025 | 12548 | -0.043 | -0.4801 | No | ||
43 | PLCG1 | 14753 | 12675 | -0.046 | -0.4867 | No | ||
44 | SOS1 | 5476 | 13046 | -0.056 | -0.5065 | No | ||
45 | ATF2 | 4418 2759 | 13664 | -0.081 | -0.5396 | No | ||
46 | PRKD1 | 2074 21075 | 13724 | -0.084 | -0.5424 | No | ||
47 | CRK | 4559 1249 | 14137 | -0.112 | -0.5643 | No | ||
48 | PIP5K1C | 5250 19929 | 14327 | -0.132 | -0.5740 | No | ||
49 | CREB1 | 3990 8782 4558 4093 | 14365 | -0.137 | -0.5755 | No | ||
50 | LCP2 | 4988 9268 | 14508 | -0.152 | -0.5825 | No | ||
51 | ZAP70 | 14271 4042 | 14538 | -0.156 | -0.5835 | No | ||
52 | CBL | 19154 | 14602 | -0.166 | -0.5863 | No | ||
53 | PRKCQ | 2873 2831 | 14829 | -0.205 | -0.5977 | No | ||
54 | GSK3A | 405 | 14926 | -0.223 | -0.6021 | No | ||
55 | VAV2 | 5848 2670 | 14978 | -0.236 | -0.6039 | No | ||
56 | PDK2 | 20285 | 15084 | -0.259 | -0.6086 | No | ||
57 | RAPGEF1 | 4218 2860 | 15230 | -0.297 | -0.6153 | No | ||
58 | LCK | 15746 | 15440 | -0.368 | -0.6252 | No | ||
59 | CASP9 | 16001 2410 2458 | 15533 | -0.412 | -0.6286 | No | ||
60 | PTPRC | 5327 9662 | 15564 | -0.428 | -0.6286 | No | ||
61 | RPS6KB1 | 7815 1207 13040 | 15722 | -0.503 | -0.6351 | No | ||
62 | ITPR2 | 9194 | 15731 | -0.509 | -0.6336 | No | ||
63 | HCK | 14787 | 15979 | -0.695 | -0.6443 | No | ||
64 | REL | 9716 | 16182 | -0.909 | -0.6517 | No | ||
65 | CASP7 | 23826 | 16324 | -1.018 | -0.6555 | No | ||
66 | HDAC5 | 1480 20205 | 16350 | -1.042 | -0.6528 | No | ||
67 | RASGRP3 | 10767 | 16689 | -1.489 | -0.6654 | Yes | ||
68 | MAP4K1 | 18313 | 16775 | -1.624 | -0.6638 | Yes | ||
69 | RASA1 | 10174 | 16815 | -1.689 | -0.6595 | Yes | ||
70 | GTF2I | 16353 5491 9863 3280 3184 | 16882 | -1.744 | -0.6564 | Yes | ||
71 | MAPK3 | 6458 11170 | 16931 | -1.809 | -0.6520 | Yes | ||
72 | CCND2 | 16987 | 17025 | -1.937 | -0.6496 | Yes | ||
73 | PIK3AP1 | 23679 | 17040 | -1.963 | -0.6429 | Yes | ||
74 | TEC | 16514 | 17287 | -2.394 | -0.6470 | Yes | ||
75 | PRKCD | 21897 | 17290 | -2.395 | -0.6380 | Yes | ||
76 | SOS2 | 21049 | 17328 | -2.499 | -0.6304 | Yes | ||
77 | MAPK14 | 23313 | 17421 | -2.682 | -0.6252 | Yes | ||
78 | NFATC1 | 23398 1999 5167 9455 1985 1957 | 17449 | -2.738 | -0.6161 | Yes | ||
79 | CARD11 | 8436 | 17478 | -2.819 | -0.6069 | Yes | ||
80 | CD79B | 20185 1309 | 17530 | -2.928 | -0.5984 | Yes | ||
81 | SH3BP2 | 16874 | 17547 | -2.956 | -0.5880 | Yes | ||
82 | RB1 | 21754 | 17554 | -2.982 | -0.5769 | Yes | ||
83 | CRKL | 4560 | 17588 | -3.053 | -0.5670 | Yes | ||
84 | GRB2 | 20149 | 17590 | -3.055 | -0.5554 | Yes | ||
85 | GSK3B | 22761 | 17596 | -3.078 | -0.5439 | Yes | ||
86 | CD19 | 17640 | 17676 | -3.314 | -0.5355 | Yes | ||
87 | JUN | 15832 | 17687 | -3.335 | -0.5233 | Yes | ||
88 | CD22 | 17881 | 17755 | -3.507 | -0.5135 | Yes | ||
89 | NFATC3 | 5169 | 17772 | -3.544 | -0.5008 | Yes | ||
90 | CD79A | 18342 | 17804 | -3.629 | -0.4886 | Yes | ||
91 | NFKBIA | 21065 | 17838 | -3.699 | -0.4763 | Yes | ||
92 | BTK | 24061 | 17851 | -3.733 | -0.4627 | Yes | ||
93 | CD81 | 8719 | 17871 | -3.794 | -0.4492 | Yes | ||
94 | PTPN18 | 14279 | 17896 | -3.874 | -0.4357 | Yes | ||
95 | CCND3 | 4489 4490 | 17924 | -3.962 | -0.4220 | Yes | ||
96 | RELA | 23783 | 17959 | -4.092 | -0.4082 | Yes | ||
97 | SYK | 21636 | 18074 | -4.548 | -0.3969 | Yes | ||
98 | BCL10 | 15397 | 18081 | -4.569 | -0.3798 | Yes | ||
99 | HCLS1 | 22770 | 18104 | -4.641 | -0.3632 | Yes | ||
100 | LAT2 | 16351 | 18112 | -4.661 | -0.3458 | Yes | ||
101 | FCGR2B | 8959 | 18125 | -4.712 | -0.3284 | Yes | ||
102 | VAV1 | 23173 | 18136 | -4.751 | -0.3108 | Yes | ||
103 | WAS | 24193 | 18166 | -4.862 | -0.2938 | Yes | ||
104 | CBLB | 5531 22734 | 18225 | -5.154 | -0.2772 | Yes | ||
105 | GAB1 | 18828 | 18283 | -5.430 | -0.2595 | Yes | ||
106 | PTK2B | 21776 | 18298 | -5.513 | -0.2392 | Yes | ||
107 | PDPK1 | 23097 | 18324 | -5.661 | -0.2189 | Yes | ||
108 | CSK | 8805 | 18359 | -5.871 | -0.1983 | Yes | ||
109 | BLK | 3205 21791 | 18378 | -5.983 | -0.1764 | Yes | ||
110 | MAPKAPK2 | 13838 | 18416 | -6.306 | -0.1543 | Yes | ||
111 | NEDD9 | 3206 21483 | 18558 | -8.130 | -0.1308 | Yes | ||
112 | PTPN6 | 17002 | 18561 | -8.216 | -0.0995 | Yes | ||
113 | BCL6 | 22624 | 18580 | -8.747 | -0.0671 | Yes | ||
114 | CD72 | 8718 | 18585 | -8.914 | -0.0332 | Yes | ||
115 | MAPK1 | 1642 11167 | 18592 | -9.104 | 0.0013 | Yes |