Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$SRF_C |
Enrichment Score (ES) | -0.4308614 |
Normalized Enrichment Score (NES) | -1.2519673 |
Nominal p-value | 0.048600882 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | RRM1 | 4150433 | 581 | 1.872 | -0.0091 | No | ||
2 | RBBP7 | 430113 450450 2370309 | 748 | 1.701 | 0.0022 | No | ||
3 | HOXB4 | 540131 | 766 | 1.681 | 0.0214 | No | ||
4 | AKAP12 | 1450739 | 900 | 1.545 | 0.0326 | No | ||
5 | BCAS3 | 4050647 | 1209 | 1.234 | 0.0307 | No | ||
6 | MAPK14 | 5290731 | 1301 | 1.150 | 0.0395 | No | ||
7 | TPM3 | 670600 3170296 5670167 6650471 | 1548 | 0.998 | 0.0381 | No | ||
8 | CDC14A | 4050132 | 1639 | 0.950 | 0.0446 | No | ||
9 | CFL1 | 2340735 | 1650 | 0.941 | 0.0553 | No | ||
10 | EML4 | 5700373 | 1651 | 0.941 | 0.0665 | No | ||
11 | YWHAZ | 1230717 | 1828 | 0.828 | 0.0669 | No | ||
12 | ABL1 | 1050593 2030050 4010114 | 1898 | 0.789 | 0.0726 | No | ||
13 | SCOC | 610048 2230053 | 1945 | 0.761 | 0.0792 | No | ||
14 | MBNL1 | 2640762 7100048 | 2031 | 0.700 | 0.0829 | No | ||
15 | SLC25A4 | 2360519 | 2158 | 0.642 | 0.0838 | No | ||
16 | ERBB2IP | 580253 1090672 | 2205 | 0.621 | 0.0887 | No | ||
17 | FOXP1 | 6510433 | 2240 | 0.605 | 0.0941 | No | ||
18 | KRTCAP2 | 5220040 | 2372 | 0.553 | 0.0936 | No | ||
19 | PPP1R12A | 4070066 4590162 | 2404 | 0.543 | 0.0984 | No | ||
20 | USP52 | 3710215 6380133 | 2509 | 0.502 | 0.0988 | No | ||
21 | DNAJB4 | 380195 2760372 3940735 | 2574 | 0.481 | 0.1010 | No | ||
22 | LCP1 | 4280397 | 2587 | 0.475 | 0.1061 | No | ||
23 | VCL | 4120487 | 2812 | 0.405 | 0.0988 | No | ||
24 | PHF12 | 870400 3130687 | 3125 | 0.306 | 0.0855 | No | ||
25 | LTBP1 | 780035 2100746 2760402 3780551 6550184 6860193 | 3171 | 0.293 | 0.0866 | No | ||
26 | GADD45G | 2510142 | 3423 | 0.240 | 0.0758 | No | ||
27 | DUSP2 | 2370184 | 3442 | 0.235 | 0.0777 | No | ||
28 | SPAG7 | 4560524 | 3478 | 0.229 | 0.0785 | No | ||
29 | MYL7 | 2480541 | 3597 | 0.205 | 0.0746 | No | ||
30 | ROCK2 | 1780035 5720025 | 3640 | 0.199 | 0.0747 | No | ||
31 | AOC3 | 6840129 | 4743 | 0.086 | 0.0160 | No | ||
32 | EFHD1 | 4070358 | 5167 | 0.065 | -0.0061 | No | ||
33 | EGR2 | 3800403 | 5178 | 0.065 | -0.0059 | No | ||
34 | GPR20 | 6620601 | 5498 | 0.052 | -0.0226 | No | ||
35 | TRIM46 | 3520609 4590010 | 5532 | 0.051 | -0.0237 | No | ||
36 | FOSB | 1940142 | 5598 | 0.049 | -0.0267 | No | ||
37 | NR2F2 | 3170609 3310577 | 5628 | 0.048 | -0.0277 | No | ||
38 | STARD13 | 540722 | 5779 | 0.043 | -0.0353 | No | ||
39 | LIN28 | 6590672 | 5814 | 0.042 | -0.0366 | No | ||
40 | POPDC2 | 2030056 | 5857 | 0.041 | -0.0384 | No | ||
41 | TCF2 | 870338 5050632 | 5933 | 0.039 | -0.0420 | No | ||
42 | THBS1 | 4560494 430288 | 5939 | 0.039 | -0.0418 | No | ||
43 | ITGB6 | 2810068 4570332 | 5945 | 0.038 | -0.0416 | No | ||
44 | ACTR3 | 1400497 | 5984 | 0.037 | -0.0432 | No | ||
45 | PRKAB2 | 6980300 | 5987 | 0.037 | -0.0429 | No | ||
46 | MITF | 380056 | 6574 | 0.024 | -0.0744 | No | ||
47 | CRK | 1230162 4780128 | 6649 | 0.022 | -0.0781 | No | ||
48 | COL8A1 | 4590050 | 7002 | 0.015 | -0.0970 | No | ||
49 | SLC2A4 | 540441 | 7047 | 0.014 | -0.0992 | No | ||
50 | IL17B | 6940711 | 7434 | 0.008 | -0.1200 | No | ||
51 | KCNK3 | 2690372 | 7469 | 0.007 | -0.1218 | No | ||
52 | MYH11 | 7100273 | 7968 | -0.001 | -0.1487 | No | ||
53 | HOXD10 | 6100039 | 8242 | -0.006 | -0.1635 | No | ||
54 | RASD2 | 3360010 | 8245 | -0.006 | -0.1635 | No | ||
55 | KCNMB1 | 4760139 | 8306 | -0.006 | -0.1667 | No | ||
56 | MYL9 | 4210750 7050138 | 8443 | -0.009 | -0.1739 | No | ||
57 | HOXA5 | 6840026 | 8445 | -0.009 | -0.1739 | No | ||
58 | TAGLN | 6660280 | 8531 | -0.010 | -0.1784 | No | ||
59 | DIXDC1 | 6980435 | 8569 | -0.011 | -0.1802 | No | ||
60 | SLC7A1 | 2450193 2710241 | 8691 | -0.013 | -0.1866 | No | ||
61 | MYO1E | 3140504 | 9122 | -0.020 | -0.2097 | No | ||
62 | EGR4 | 3120750 | 9184 | -0.021 | -0.2127 | No | ||
63 | ACTA1 | 840538 | 9285 | -0.023 | -0.2179 | No | ||
64 | ASPA | 3290400 | 9578 | -0.028 | -0.2334 | No | ||
65 | FOSL1 | 430021 | 9630 | -0.029 | -0.2358 | No | ||
66 | MEIS1 | 1400575 | 10393 | -0.044 | -0.2765 | No | ||
67 | LPP | 1660541 | 10461 | -0.046 | -0.2796 | No | ||
68 | NKX2-2 | 4150731 | 10656 | -0.050 | -0.2895 | No | ||
69 | CNN1 | 510707 | 10741 | -0.052 | -0.2935 | No | ||
70 | NR4A1 | 6290161 | 10821 | -0.054 | -0.2971 | No | ||
71 | NPAS2 | 770670 | 10825 | -0.054 | -0.2966 | No | ||
72 | IER2 | 2030008 | 10975 | -0.058 | -0.3040 | No | ||
73 | SSH3 | 6290110 6650497 | 11049 | -0.060 | -0.3072 | No | ||
74 | DSTN | 3140592 | 11071 | -0.061 | -0.3076 | No | ||
75 | TANK | 1090020 2060458 2370400 | 11076 | -0.061 | -0.3071 | No | ||
76 | CALD1 | 1770129 1940397 | 11403 | -0.070 | -0.3239 | No | ||
77 | ITGA7 | 1230739 | 11512 | -0.073 | -0.3289 | No | ||
78 | TNNC1 | 1990575 | 11645 | -0.077 | -0.3351 | No | ||
79 | PLN | 3940132 | 11784 | -0.083 | -0.3416 | No | ||
80 | RASSF2 | 2480079 5720546 | 11794 | -0.083 | -0.3411 | No | ||
81 | CACNA1B | 1740010 5360593 | 11890 | -0.086 | -0.3452 | No | ||
82 | MYO1B | 770372 | 12152 | -0.097 | -0.3582 | No | ||
83 | CA3 | 870687 5890390 | 12159 | -0.097 | -0.3574 | No | ||
84 | TADA3L | 4210070 5720088 6660333 | 12236 | -0.100 | -0.3603 | No | ||
85 | HOXB5 | 2900538 | 12257 | -0.101 | -0.3602 | No | ||
86 | DMD | 1740041 3990332 | 12380 | -0.107 | -0.3655 | No | ||
87 | HOXA3 | 3610632 6020358 | 12646 | -0.121 | -0.3784 | No | ||
88 | DLL1 | 1770377 | 12872 | -0.134 | -0.3890 | No | ||
89 | RSU1 | 4850372 | 12932 | -0.138 | -0.3906 | No | ||
90 | SRD5A2 | 6840433 | 12982 | -0.141 | -0.3915 | No | ||
91 | MYLK | 4010600 7000364 | 13035 | -0.144 | -0.3926 | No | ||
92 | ITGB1BP2 | 6200129 | 13080 | -0.148 | -0.3933 | No | ||
93 | JPH2 | 940041 5860026 | 13108 | -0.150 | -0.3929 | No | ||
94 | STAT5B | 6200026 | 13123 | -0.151 | -0.3919 | No | ||
95 | FOXP2 | 3520561 4150372 4760524 | 13179 | -0.155 | -0.3930 | No | ||
96 | TGFB1I1 | 2060288 6550450 | 13285 | -0.163 | -0.3968 | No | ||
97 | SYNCRIP | 1690195 3140113 4670279 | 13338 | -0.167 | -0.3976 | No | ||
98 | MYO18B | 7100670 | 13350 | -0.168 | -0.3962 | No | ||
99 | ACTG2 | 4780180 | 13871 | -0.217 | -0.4218 | No | ||
100 | PLCB3 | 4670402 | 13955 | -0.227 | -0.4235 | No | ||
101 | ACVR1 | 6840671 | 13964 | -0.228 | -0.4213 | No | ||
102 | FOXE3 | 6900102 | 14018 | -0.234 | -0.4213 | No | ||
103 | SRF | 70139 2320039 | 14038 | -0.235 | -0.4196 | No | ||
104 | GGN | 1410528 4210082 5290170 | 14150 | -0.249 | -0.4226 | No | ||
105 | LMCD1 | 1740484 2190097 | 14224 | -0.260 | -0.4234 | No | ||
106 | GFPT2 | 2370129 | 14246 | -0.263 | -0.4214 | No | ||
107 | MRGPRF | 4780746 | 14252 | -0.264 | -0.4185 | No | ||
108 | NKX6-2 | 2450332 3120333 | 14266 | -0.266 | -0.4161 | No | ||
109 | LRP5 | 2100397 3170484 | 14478 | -0.295 | -0.4240 | No | ||
110 | COL1A2 | 380364 | 14606 | -0.319 | -0.4271 | Yes | ||
111 | DUSP6 | 5910286 7100070 | 14628 | -0.323 | -0.4243 | Yes | ||
112 | MAP1A | 4920576 | 14671 | -0.329 | -0.4227 | Yes | ||
113 | MATR3 | 1940170 5340278 | 14770 | -0.346 | -0.4239 | Yes | ||
114 | TITF1 | 3390554 4540292 | 14772 | -0.346 | -0.4198 | Yes | ||
115 | DVL3 | 360156 5390075 | 14939 | -0.380 | -0.4242 | Yes | ||
116 | ELAVL4 | 50735 3360086 5220167 | 14942 | -0.381 | -0.4198 | Yes | ||
117 | FOS | 1850315 | 14971 | -0.386 | -0.4167 | Yes | ||
118 | NR2F1 | 4120528 360402 | 14973 | -0.386 | -0.4121 | Yes | ||
119 | ACTB | 1660736 2030204 2060215 5050047 | 15190 | -0.433 | -0.4187 | Yes | ||
120 | EGR3 | 6940128 | 15198 | -0.434 | -0.4139 | Yes | ||
121 | MCAM | 5130270 6620577 | 15210 | -0.437 | -0.4092 | Yes | ||
122 | JUNB | 4230048 | 15452 | -0.504 | -0.4163 | Yes | ||
123 | POU3F4 | 870274 | 15540 | -0.535 | -0.4146 | Yes | ||
124 | CFL2 | 380239 6200368 | 15581 | -0.551 | -0.4102 | Yes | ||
125 | MRVI1 | 4810338 4850601 5900441 | 15642 | -0.573 | -0.4066 | Yes | ||
126 | CYR61 | 1240408 5290026 4120452 6550008 | 15866 | -0.650 | -0.4109 | Yes | ||
127 | SIPA1 | 5220687 | 15944 | -0.687 | -0.4069 | Yes | ||
128 | FGFRL1 | 6370047 | 16069 | -0.745 | -0.4047 | Yes | ||
129 | ANXA6 | 2190014 | 16137 | -0.771 | -0.3991 | Yes | ||
130 | PDLIM4 | 3990358 | 16138 | -0.772 | -0.3899 | Yes | ||
131 | TLE3 | 580040 4730121 | 16160 | -0.780 | -0.3817 | Yes | ||
132 | RHOJ | 6660176 | 16164 | -0.781 | -0.3725 | Yes | ||
133 | RUNDC1 | 2450037 | 16247 | -0.824 | -0.3671 | Yes | ||
134 | EMILIN2 | 70253 | 16321 | -0.857 | -0.3608 | Yes | ||
135 | ARHGAP1 | 2810010 5270064 | 16374 | -0.884 | -0.3531 | Yes | ||
136 | TOP1 | 770471 4060632 6650324 | 16558 | -0.968 | -0.3514 | Yes | ||
137 | TAZ | 7100193 | 16586 | -0.983 | -0.3412 | Yes | ||
138 | RGS3 | 60670 540736 1340180 1500369 3390735 4010131 4610402 6380114 | 16656 | -1.004 | -0.3329 | Yes | ||
139 | TUFT1 | 540047 2370010 | 16756 | -1.046 | -0.3258 | Yes | ||
140 | CAP1 | 2650278 | 16901 | -1.136 | -0.3200 | Yes | ||
141 | PFN1 | 6130132 | 16915 | -1.144 | -0.3070 | Yes | ||
142 | FHL2 | 1400008 | 16953 | -1.165 | -0.2951 | Yes | ||
143 | DAPK3 | 4590121 | 17230 | -1.344 | -0.2940 | Yes | ||
144 | CKM | 1450524 | 17235 | -1.346 | -0.2782 | Yes | ||
145 | KCTD15 | 2810735 | 17500 | -1.526 | -0.2742 | Yes | ||
146 | GRK6 | 1500053 | 17717 | -1.715 | -0.2654 | Yes | ||
147 | CNN2 | 2230433 5270446 | 17910 | -1.904 | -0.2531 | Yes | ||
148 | EGR1 | 4610347 | 17946 | -1.942 | -0.2318 | Yes | ||
149 | MUS81 | 6660184 | 17964 | -1.968 | -0.2092 | Yes | ||
150 | PDLIM7 | 4780136 | 17992 | -1.999 | -0.1868 | Yes | ||
151 | MYL6 | 60563 6100152 | 18078 | -2.094 | -0.1664 | Yes | ||
152 | DUSP10 | 2850673 3360064 | 18250 | -2.336 | -0.1477 | Yes | ||
153 | PNKP | 4610685 5720605 | 18253 | -2.346 | -0.1198 | Yes | ||
154 | ASB2 | 4760168 | 18396 | -2.652 | -0.0958 | Yes | ||
155 | ARPC4 | 2900056 | 18417 | -2.722 | -0.0644 | Yes | ||
156 | PADI2 | 2940092 6420136 | 18499 | -2.975 | -0.0332 | Yes | ||
157 | FLNA | 5390193 | 18554 | -3.307 | 0.0034 | Yes |